Targeting MYC in cancer therapy: RNA processing offers new opportunities von Koh, Cheryl M, Sabò, Arianna, Guccione, Ernesto

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Therapeutic Targeting of RNA Splicing Catalysis through Inhibition of Protein Arginine Methylation von Fong, Jia Yi, Pignata, Luca, Goy, Pierre-Alexis, Kawabata, Kimihito Cojin, Lee, Stanley Chun-Wei, Koh, Cheryl M., Musiani, Daniele, Massignani, Enrico, Kotini, Andriana G., Penson, Alex, Wun, Cheng Mun, Shen, Yudao, Schwarz, Megan, Low, Diana HP, Rialdi, Alexander, Ki, Michelle, Wollmann, Heike, Mzoughi, Slim, Gay, Florence, Thompson, Christine, Hart, Timothy, Barbash, Olena, Luciani, Genna M., Szewczyk, Magdalena M., Wouters, Bas J., Delwel, Ruud, Papapetrou, Eirini P., Barsyte-Lovejoy, Dalia, Arrowsmith, Cheryl H., Minden, Mark D., Jin, Jian, Melnick, Ari, Bonaldi, Tiziana, Abdel-Wahab, Omar, Guccione, Ernesto

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Nuclear MYC protein overexpression is an early alteration in human prostate carcinogenesis von Gurel, Bora, Iwata, Tsuyoshi, M Koh, Cheryl, Jenkins, Robert B, Lan, Fusheng, Van Dang, Chi, Hicks, Jessica L, Morgan, James, Cornish, Toby C, Sutcliffe, Siobhan, Isaacs, William B, Luo, Jun, De Marzo, Angelo M

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GRHL2-miR-200-ZEB1 maintains the epithelial status of ovarian cancer through transcriptional regulation and histone modification von Chung, Vin Yee, Tan, Tuan Zea, Tan, Ming, Wong, Meng Kang, Kuay, Kuee Theng, Yang, Zhe, Ye, Jieru, Muller, Julius, Koh, Cheryl M., Guccione, Ernesto, Thiery, Jean Paul, Huang, Ruby Yun-Ju

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Preparation of Cells for Microscopy using Cytospin von Koh, Cheryl M.

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MYC overexpression induces prostatic intraepithelial neoplasia and loss of Nkx3.1 in mouse luminal epithelial cells von Iwata, Tsuyoshi, Schultz, Denise, Hicks, Jessica, Hubbard, Gretchen K, Mutton, Laura N, Lotan, Tamara L, Bethel, Carlise, Lotz, Matthew T, Yegnasubramanian, Srinivasan, Nelson, William G, Dang, Chi V, Xu, MengMeng, Anele, Uzoma, Koh, Cheryl M, Bieberich, Charles J, De Marzo, Angelo M

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Alterations in Nucleolar Structure and Gene Expression Programs in Prostatic Neoplasia Are Driven by the MYC Oncogene von Koh, Cheryl M, Gurel, Bora, Sutcliffe, Siobhan, Aryee, Martin J, Schultz, Denise, Iwata, Tsuyoshi, Uemura, Motohide, Zeller, Karen I, Anele, Uzoma, Zheng, Qizhi, Hicks, Jessica L, Nelson, William G, Dang, Chi V, Yegnasubramanian, Srinivasan, De Marzo, Angelo M

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Preparation of Cells for Microscopy using Chamber Slides and Coverslips von Koh, Cheryl M.

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MYC regulates the core pre-mRNA splicing machinery as an essential step in lymphomagenesis von Koh, Cheryl M., Bezzi, Marco, Low, Diana H. P., Ang, Wei Xia, Teo, Shun Xie, Gay, Florence P. H., Al-Haddawi, Muthafar, Tan, Soo Yong, Osato, Motomi, Sabò, Arianna, Amati, Bruno, Wee, Keng Boon, Guccione, Ernesto

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Telomerase regulates MYC-driven oncogenesis independent of its reverse transcriptase activity von Koh, Cheryl M, Khattar, Ekta, Leow, Shi Chi, Liu, Chia Yi, Muller, Julius, Ang, Wei Xia, Li, Yinghui, Franzoso, Guido, Li, Shang, Guccione, Ernesto, Tergaonkar, Vinay

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Antisense oligonucleotide-mediated MDM4 exon 6 skipping impairs tumor growth von Dewaele, Michael, Tabaglio, Tommaso, Willekens, Karen, Bezzi, Marco, Teo, Shun Xie, Low, Diana H P, Koh, Cheryl M, Rambow, Florian, Fiers, Mark, Rogiers, Aljosja, Radaelli, Enrico, Al-Haddawi, Muthafar, Tan, Soo Yong, Hermans, Els, Amant, Frederic, Yan, Hualong, Lakshmanan, Manikandan, Koumar, Ratnacaram Chandrahas, Lim, Soon Thye, Derheimer, Frederick A, Campbell, Robert M, Bonday, Zahid, Tergaonkar, Vinay, Shackleton, Mark, Blattner, Christine, Marine, Jean-Christophe, Guccione, Ernesto

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Myc enforces overexpression of EZH2 in early prostatic neoplasia via transcriptional and post-transcriptional mechanisms von Koh, Cheryl M, Iwata, Tsuyoshi, Zheng, Qizhi, Bethel, Carlise, Yegnasubramanian, Srinivasan, De Marzo, Angelo M

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Discovery and Optimization of the First ATP Competitive Type-III c‑MET Inhibitor von Michaelides, Iacovos N., Collie, Gavin W., Börjesson, Ulf, Vasalou, Christina, Alkhatib, Omar, Barlind, Louise, Cheung, Tony, Dale, Ian L., Embrey, Kevin J., Hennessy, Edward J., Khurana, Puneet, Koh, Cheryl M., Lamb, Michelle L., Liu, Jianming, Moss, Thomas A., O’Neill, Daniel J., Phillips, Christopher, Shaw, Joseph, Snijder, Arjan, Storer, R. Ian, Stubbs, Christopher J., Han, Fujin, Li, Chengzhi, Qiao, Jingchuan, Sun, Dong-Qing, Wang, Jingwen, Wang, Peng, Yang, Wenzhen

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MYC and Prostate Cancer von Koh, Cheryl M, Bieberich, Charles J, Dang, Chi V, Nelson, William G, Yegnasubramanian, Srinivasan, De Marzo, Angelo M

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PRDM15 is a key regulator of metabolism critical to sustain B-cell lymphomagenesis von Mzoughi, Slim, Fong, Jia Yi, Papadopoli, David, Koh, Cheryl M., Hulea, Laura, Pigini, Paolo, Di Tullio, Federico, Andreacchio, Giuseppe, Hoppe, Michal Marek, Wollmann, Heike, Low, Diana, Caldez, Matias J., Peng, Yanfen, Torre, Denis, Zhao, Julia N., Uchenunu, Oro, Varano, Gabriele, Motofeanu, Corina-Mihaela, Lakshmanan, Manikandan, Teo, Shun Xie, Wun, Cheng Mun, Perini, Giovanni, Tan, Soo Yong, Ong, Chee Bing, Al-Haddawi, Muthafar, Rajarethinam, Ravisankar, Hue, Susan Swee-Shan, Lim, Soon Thye, Ong, Choon Kiat, Huang, Dachuan, Ng, Siok-Bian, Bernstein, Emily, Hasson, Dan, Wee, Keng Boon, Kaldis, Philipp, Jeyasekharan, Anand, Dominguez-sola, David, Topisirovic, Ivan, Guccione, Ernesto

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Structural and Molecular Insight into Resistance Mechanisms of First Generation cMET Inhibitors von Collie, Gavin W, Koh, Cheryl M, O’Neill, Daniel J, Stubbs, Christopher J, Khurana, Puneet, Eddershaw, Alice, Snijder, Arjan, Mauritzson, Fredrik, Barlind, Louise, Dale, Ian L, Shaw, Joseph, Phillips, Christopher, Hennessy, Edward J, Cheung, Tony, Narvaez, Ana J

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Molecular alterations in prostate cancer as diagnostic, prognostic, and therapeutic targets von Gurel, Bora, Iwata, Tsuyoshi, Koh, Cheryl M, Yegnasubramanian, Srinivasan, Nelson, William G, De Marzo, Angelo M

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Treatment with riboflavin and ultraviolet light prevents alloimmunization to platelet transfusions and cardiac transplants von ASANO, Hiroshi, LEE, Chih-Yuan, FOX-TALBOT, Karen, KOH, Cheryl M, ERDINC, Melek M, MARSCHNER, Susanne, KEIL, Shawn, GOODRICH, Raymond P, BALDWIN, William M

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Iron-responsive degradation of iron-regulatory protein 1 does not require the Fe-S cluster von Clarke, Stephen L, Vasanthakumar, Aparna, Anderson, Sheila A, Pondarré, Corinne, Koh, Cheryl M, Deck, Kathryn M, Pitula, Joseph S, Epstein, Charles J, Fleming, Mark D, Eisenstein, Richard S

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Isolation of Genomic DNA from Mammalian Cells von Koh, Cheryl M.

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