INK4 Tumor Suppressor Proteins Mediate Resistance to CDK4/6 Kinase Inhibitors von Li, Qing, Jiang, Baishan, Guo, Jiaye, Shao, Hong, Del Priore, Isabella S, Chang, Qing, Kudo, Rei, Li, Zhiqiang, Razavi, Pedram, Liu, Bo, Boghossian, Andrew S, Rees, Matthew G, Ronan, Melissa M, Roth, Jennifer A, Donovan, Katherine A, Palafox, Marta, Reis-Filho, Jorge S, de Stanchina, Elisa, Fischer, Eric S, Rosen, Neal, Serra, Violeta, Koff, Andrew, Chodera, John D, Gray, Nathanael S, Chandarlapaty, Sarat

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ATRX is a regulator of therapy induced senescence in human cells von Kovatcheva, Marta, Liao, Will, Klein, Mary E., Robine, Nicolas, Geiger, Heather, Crago, Aimee M., Dickson, Mark A., Tap, William D., Singer, Samuel, Koff, Andrew

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Pilot study of bempegaldesleukin in combination with nivolumab in patients with metastatic sarcoma von D’Angelo, Sandra P., Richards, Allison L., Conley, Anthony P., Woo, Hyung Jun, Dickson, Mark A., Gounder, Mrinal, Kelly, Ciara, Keohan, Mary Louise, Movva, Sujana, Thornton, Katherine, Rosenbaum, Evan, Chi, Ping, Nacev, Benjamin, Chan, Jason E., Slotkin, Emily K., Kiesler, Hannah, Adamson, Travis, Ling, Lilan, Rao, Pavitra, Patel, Shreyaskumar, Livingston, Jonathan A., Singer, Samuel, Agaram, Narasimhan P., Antonescu, Cristina R., Koff, Andrew, Erinjeri, Joseph P., Hwang, Sinchun, Qin, Li-Xuan, Donoghue, Mark T. A., Tap, William D.

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A549 in-silico 1.0: A first computational model to simulate cell cycle dependent ion current modulation in the human lung adenocarcinoma von Langthaler, Sonja, Rienmueller, Theresa, Scheruebel, Susanne, Pelzmann, Brigitte, Shrestha, Niroj, Zorn-Pauly, Klaus, Schreibmayer, Wolfgang, Koff, Andrew, Baumgartner, Christian

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Cell-cycle inhibitors: three families united by a common cause von Vidal, Anxo, Koff, Andrew

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PDLIM7 and CDH18 regulate the turnover of MDM2 during CDK4/6 inhibitor therapy-induced senescence von Klein, Mary E., Dickson, Mark A., Antonescu, Cristina, Qin, Li-Xuan, Dooley, Scott J., Barlas, Afsar, Manova, Katia, Schwartz, Gary K., Crago, Aimee M., Singer, Samuel, Koff, Andrew, Tap, William D.

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MDM2 turnover and expression of ATRX determine the choice between quiescence and senescence in response to CDK4 inhibition von Kovatcheva, Marta, Liu, David D, Dickson, Mark A, Klein, Mary E, O'Connor, Rachael, Wilder, Fatima O, Socci, Nicholas D, Tap, William D, Schwartz, Gary K, Singer, Samuel, Crago, Aimee M, Koff, Andrew

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Phase 2 study of the CDK4 inhibitor abemaciclib in dedifferentiated liposarcoma von Dickson, Mark Andrew, Koff, Andrew, D'Angelo, Sandra P., Gounder, Mrinal M., Keohan, Mary Louise, Kelly, Ciara Marie, Chi, Ping, Antonescu, Cristina R., Landa, Jonathan, Qin, Li-Xuan, Crago, Aimee Marie, Singer, Samuel, Tap, William D.

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How to decrease p27Kip1 levels during tumor development von Koff, Andrew

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Hdm2- and proteasome-dependent turnover limits p21 accumulation during S phase von Ciznadija, Daniel, Zhu, Xin-Hua, Koff, Andrew

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Interweaving the Cell Cycle Machinery with Cell Differentiation von Miller, Jeffrey P., Yeh, Nancy, Vidal, Anxo, Koff, Andrew

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The p53 tumor suppressor protein is a critical regulator of hematopoietic stem cell behavior von Liu, Yan, Elf, Shannon E., Asai, Takashi, Miyata, Yasuhiko, Liu, Yuhui, Sashida, Goro, Huang, Gang, Di Giandomenico, Silvana, Koff, Andrew, Nimer, Stephen D.

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ZIC1 Overexpression Is Oncogenic in Liposarcoma von BRILL, Elliott, GOBBLE, Ryan, TAYLOR, Barry S, SANDER, Chris, KOFF, Andrew, SINGER, Samuel, ANGELES, Christina, LAGOS-QUINTANA, Mariana, CRAGO, Aimee, LAXA, Bernadette, DECAROLIS, Penelope, LEI ZHANG, ANTONESCU, Cristina, SOCCI, Nicholas D

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Misexpression of Cyclin B3 Leads to Aberrant Spermatogenesis von Refik-Rogers, Jale, Manova, Katia, Koff, Andrew

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CDK4/6 Inhibitors: The Mechanism of Action May Not Be as Simple as Once Thought von Klein, Mary E., Kovatcheva, Marta, Davis, Lara E., Tap, William D., Koff, Andrew

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Mechanistic understanding of the role of ATRX in senescence provides new insight for combinatorial therapies with CDK4 inhibitors von Kovatcheva, Marta, Klein, Mary E., Tap, William D., Koff, Andrew

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Enhanced growth of mice lacking the cyclin-dependent kinase inhibitor function of p27(Kip1) von Kiyokawa, H, Kineman, R D, Manova-Todorova, K O, Soares, V C, Hoffman, E S, Ono, M, Khanam, D, Hayday, A C, Frohman, L A, Koff, A

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A U-Rich Element in the 5′ Untranslated Region Is Necessary for the Translation of p27 mRNA von Millard, S. Sean, Vidal, Anxo, Markus, Maurice, Koff, Andrew

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Characterization and Expression of Mammalian Cyclin B3, a Prepachytene Meiotic Cyclin von Nguyen, T B, Manova, K, Capodieci, P, Lindon, C, Bottega, S, Wang, X, Refik-Rogers, J, Pines, J, Wolgemuth, D J, Koff, A

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p27 and Rb Are on Overlapping Pathways Suppressing Tumorigenesis in Mice von Park, Michele S., Rosai, Juan, Nguyen, Hai T., Capodieci, Paola, Cordon-Cardo, Carlos, Koff, Andrew

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