Transcription Factor Inhibition: Lessons Learned and Emerging Targets von Chen, Andrew, Koehler, Angela N.

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Massively parallel pooled screening reveals genomic determinants of nanoparticle delivery von Boehnke, Natalie, Straehla, Joelle P, Safford, Hannah C, Kocak, Mustafa, Rees, Matthew G, Ronan, Melissa, Rosenberg, Danny, Adelmann, Charles H, Chivukula, Raghu R, Nabar, Namita, Berger, Adam G, Lamson, Nicholas G, Cheah, Jaime H, Li, Hojun, Roth, Jennifer A, Koehler, Angela N, Hammond, Paula T

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Small molecules of different origins have distinct distributions of structural complexity that correlate with protein-binding profiles von Clemons, Paul A., Bodycombe, Nicole E., Carrinski, Hyman A., Wilson, J. Anthony, Shamji, Alykhan F., Wagner, Bridget K., Koehler, Angela N., Schreiber, Stuart L.

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Nailing Down a Notoriously Elusive Cancer Target: Direct Inhibition of MYC by a Covalent Small Molecule von Henley, Matthew J., Doyle, Shelby K., Koehler, Angela N.

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Nuclear to cytoplasmic transport is a druggable dependency in MYC-driven hepatocellular carcinoma von Deutzmann, Anja, Sullivan, Delaney K., Dhanasekaran, Renumathy, Li, Wei, Chen, Xinyu, Tong, Ling, Mahauad-Fernandez, Wadie D., Bell, John, Mosley, Adriane, Koehler, Angela N., Li, Yulin, Felsher, Dean W.

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Advances in targeting ‘undruggable’ transcription factors with small molecules von Henley, Madeleine J., Koehler, Angela N.

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Binding Affinity and Kinetic Analysis of Targeted Small Molecule-Modified Nanoparticles von Tassa, Carlos, Duffner, Jay L, Lewis, Timothy A, Weissleder, Ralph, Schreiber, Stuart L, Koehler, Angela N, Shaw, Stanley Y

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A complex task? Direct modulation of transcription factors with small molecules von Koehler, Angela N

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Identifying the Proteins to Which Small-Molecule Probes and Drugs Bind in Cells von Ong, Shao-En, Schenone, Monica, Margolin, Adam A., Li, Xiaoyu, Do, Kathy, Doud, Mary K., Mani, D. R., Kuai, Letian, Wang, Xiang, Wood, John L., Tolliday, Nicola J., Koehler, Angela N., Marcaurelle, Lisa A., Golub, Todd R., Gould, Robert J., Schreiber, Stuart L., Carr, Steven A.

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Recent discoveries and applications involving small-molecule microarrays von Hong, Jiyoung A, Neel, Dylan V, Wassaf, Dina, Caballero, Francisco, Koehler, Angela N

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Quantifying structure and performance diversity for sets of small molecules comprising small-molecule screening collections von Clemons, Paul A, Wilson, J. Anthony, Dančík, Vlado, Muller, Sandrine, Carrinski, Hyman A, Wagner, Bridget K, Koehler, Angela N, Schreiber, Stuart L

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Addressing Transcriptional Dysregulation in Cancer through CDK9 Inhibition von Toure, Mohammed A., Koehler, Angela N.

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A Novel Small Molecule Activator of Nuclear Receptor SHP Inhibits HCC Cell Migration via Suppressing Ccl2 von Yang, Zhihong, Koehler, Angela N, Wang, Li

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Printing Small Molecules as Microarrays and Detecting Protein−Ligand Interactions en Masse von MacBeath, Gavin, Koehler, Angela N, Schreiber, Stuart L

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A pipeline for ligand discovery using small-molecule microarrays von Duffner, Jay L, Clemons, Paul A, Koehler, Angela N

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Chemical perturbation of an intrinsically disordered region of TFIID distinguishes two modes of transcription initiation von Zhang, Zhengjian, Boskovic, Zarko, Hussain, Mahmud M, Hu, Wenxin, Inouye, Carla, Kim, Han-Je, Abole, A Katherine, Doud, Mary K, Lewis, Timothy A, Koehler, Angela N, Schreiber, Stuart L, Tjian, Robert

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New opportunities to overcome T cell dysfunction: the role of transcription factors and how to target them von Wu, Bocheng, Koehler, Angela N., Westcott, Peter M.K.

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Discovery of an Inhibitor of a Transcription Factor Using Small Molecule Microarrays and Diversity-Oriented Synthesis von Koehler, Angela N, Shamji, Alykhan F, Schreiber, Stuart L

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A method for the covalent capture and screening of diverse small molecules in a microarray format von Koehler, Angela N, Bradner, James E, McPherson, Olivia M

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Roscovitine Inhibits EBNA1 Serine 393 Phosphorylation, Nuclear Localization, Transcription, and Episome Maintenance von KANG, Myung-Soo, EUN KYUNG LEE, SONI, Vishal, LEWIS, Timothy A, KOEHLER, Angela N, SRINIVASAN, Viswanathan, KIEFF, Elliott

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