Sulfhydration mediates neuroprotective actions of parkin von Vandiver, M. Scott, Paul, Bindu D., Xu, Risheng, Karuppagounder, Senthilkumar, Rao, Feng, Snowman, Adele M., Seok Ko, Han, Il Lee, Yun, Dawson, Valina L., Dawson, Ted M., Sen, Nilkantha, Snyder, Solomon H.

Volltext

Midbrain-like Organoids from Human Pluripotent Stem Cells Contain Functional Dopaminergic and Neuromelanin-Producing Neurons von Jo, Junghyun, Xiao, Yixin, Sun, Alfred Xuyang, Cukuroglu, Engin, Tran, Hoang-Dai, Göke, Jonathan, Tan, Zi Ying, Saw, Tzuen Yih, Tan, Cheng-Peow, Lokman, Hidayat, Lee, Younghwan, Kim, Donghoon, Ko, Han Seok, Kim, Seong-Oh, Park, Jae Hyeon, Cho, Nam-Joon, Hyde, Thomas M., Kleinman, Joel E., Shin, Joo Heon, Weinberger, Daniel R., Tan, Eng King, Je, Hyunsoo Shawn, Ng, Huck-Hui

Volltext

DJ-1 gene deletion reveals that DJ-1 is an atypical peroxiredoxin-like peroxidase von Andres-Mateos, Eva, Perier, Celine, Zhang, Li, Blanchard-Fillion, Beatrice, Greco, Todd M, Thomas, Bobby, Ko, Han Seok, Sasaki, Masayuki, Ischiropoulos, Harry, Przedborski, Serge, Dawson, Ted M, Dawson, Valina L

Volltext

Genetic Animal Models of Parkinson's Disease von Dawson, Ted M., Ko, Han Seok, Dawson, Valina L.

Volltext

Mitochondrial dysfunction and mitophagy defect triggered by heterozygous GBA mutations von Li, Hongyu, Ham, Ahrom, Ma, Thong Chi, Kuo, Sheng-Han, Kanter, Ellen, Kim, Donghoon, Ko, Han Seok, Quan, Yi, Sardi, Sergio Pablo, Li, Aiqun, Arancio, Ottavio, Kang, Un Jung, Sulzer, David, Tang, Guomei

Volltext

Block of A1 astrocyte conversion by microglia is neuroprotective in models of Parkinson’s disease von Yun, Seung Pil, Kam, Tae-In, Panicker, Nikhil, Kim, SangMin, Oh, Yumin, Park, Jong-Sung, Kwon, Seung-Hwan, Park, Yong Joo, Karuppagounder, Senthilkumar S., Park, Hyejin, Kim, Sangjune, Oh, Nayeon, Kim, Nayoung Alice, Lee, Saebom, Brahmachari, Saurav, Mao, Xiaobo, Lee, Jun Hee, Kumar, Manoj, An, Daniel, Kang, Sung-Ung, Lee, Yunjong, Lee, Kang Choon, Na, Dong Hee, Kim, Donghoon, Lee, Sang Hun, Roschke, Viktor V., Liddelow, Shane A., Mari, Zoltan, Barres, Ben A., Dawson, Valina L., Lee, Seulki, Dawson, Ted M., Ko, Han Seok

Volltext

PARIS (ZNF746) Repression of PGC-1α Contributes to Neurodegeneration in Parkinson's Disease von Shin, Joo-Ho, Ko, Han Seok, Kang, Hochul, Lee, Yunjong, Lee, Yun-Il, Pletinkova, Olga, Troconso, Juan C., Dawson, Valina L., Dawson, Ted M.

Volltext

Identification of Far Upstream Element-binding Protein-1 as an Authentic Parkin Substrate von Ko, Han Seok, Kim, Seong Who, Sriram, Sathya R., Dawson, Valina L., Dawson, Ted M.

Volltext

The c-Abl inhibitor, Nilotinib, protects dopaminergic neurons in a preclinical animal model of Parkinson's disease von Karuppagounder, Senthilkumar S., Brahmachari, Saurav, Lee, Yunjong, Dawson, Valina L., Dawson, Ted M., Ko, Han Seok

Volltext

Levodopa-Induced Dyskinesia in Parkinson's Disease: Pathogenesis and Emerging Treatment Strategies von Kwon, Destany K, Kwatra, Mohit, Wang, Jing, Ko, Han Seok

Volltext

Sulfhydration mediates neuroprotective actions of parkin von Vandiver, M. Scott, Paul, Bindu D., Xu, Risheng, Karuppagounder, Senthilkumar, Rao, Feng, Snowman, Adele M., Seok Ko, Han, Il Lee, Yun, Dawson, Valina L., Dawson, Ted M., Sen, Nilkantha, Snyder, Solomon H.

Volltext

Relative Sensitivity of Parkin and Other Cysteine-containing Enzymes to Stress-induced Solubility Alterations von Wong, Esther S.P., Tan, Jeanne M.M., Wang, Cheng, Zhang, Zhenshui, Tay, Shiam-Peng, Zaiden, Norazean, Ko, Han Seok, Dawson, Valina L., Dawson, Ted M., Lim, Kah-Leong

Volltext

PINK1-Dependent Recruitment of Parkin to Mitochondria in Mitophagy von Vives-Bauza, Cristofol, Zhou, Chun, Huang, Yong, Cui, Mei, de Vries, Rosa L. A., Kim, Jiho, May, Jessica, Tocilescu, Maja Aleksandra, Liu, Wencheng, Ko, Han Seok, Magrané, Jordi, Moore, Darren J., Dawson, Valina L., Grailhe, Regis, Dawson, Ted M., Li, Chenjian, Tieu, Kim, Przedborski, Serge, Snyder, Solomon H.

Volltext

Parthanatos mediates AIMP2-activated age-dependent dopaminergic neuronal loss von Lee, Yunjong, Karuppagounder, Senthilkumar S, Shin, Joo-Ho, Lee, Yun-Il, Ko, Han Seok, Swing, Debbie, Jiang, Haisong, Kang, Sung-Ung, Lee, Byoung Dae, Kang, Ho Chul, Kim, Donghoon, Tessarollo, Lino, Dawson, Valina L, Dawson, Ted M

Volltext

PINK1 Primes Parkin-Mediated Ubiquitination of PARIS in Dopaminergic Neuronal Survival von Lee, Yunjong, Stevens, Daniel A., Kang, Sung-Ung, Jiang, Haisong, Lee, Yun-Il, Ko, Han Seok, Scarffe, Leslie A., Umanah, George E., Kang, Hojin, Ham, Sangwoo, Kam, Tae-In, Allen, Kathleen, Brahmachari, Saurav, Kim, Jungwoo Wren, Neifert, Stewart, Yun, Seung Pil, Fiesel, Fabienne C., Springer, Wolfdieter, Dawson, Valina L., Shin, Joo-Ho, Dawson, Ted M.

Volltext

Robust kinase- and age-dependent dopaminergic and norepinephrine neurodegeneration in LRRK2 G2019S transgenic mice von Xiong, Yulan, Neifert, Stewart, Karuppagounder, Senthilkumar S., Liu, Qinfang, Stankowski, Jeannette N., Lee, Byoung Dae, Ko, Han Seok, Lee, Yunjong, Grima, Jonathan C., Mao, Xiaobo, Jiang, Haisong, Kang, Sung-Ung, Swing, Deborah A., Iacovitti, Lorraine, Tessarollo, Lino, Dawson, Ted M., Dawson, Valina L.

Volltext

Inhibitors of leucine-rich repeat kinase-2 protect against models of Parkinson's disease von Dawson, Valina L, Dawson, Ted M, Lee, Byoung Dae, Shin, Joo-Ho, VanKampen, Jackalina, Petrucelli, Leonard, West, Andrew B, Ko, Han Seok, Lee, Yun-Il, Maguire-Zeiss, Kathleen A, Bowers, William J, Federoff, Howard J

Volltext

Phosphorylation by the c-Abl protein tyrosine kinase inhibits parkin's ubiquitination and protective function von Ko, Han Seok, Lee, Yunjong, Shin, Joo-Ho, Karuppagounder, Senthilkumar S., Gadad, Bharathi Shrikanth, Koleske, Anthony J., Pletnikova, Olga, Troncoso, Juan C., Dawson, Valina L., Dawson, Ted M.

Volltext

Blocking microglial activation of reactive astrocytes is neuroprotective in models of Alzheimer's disease von Park, Jong-Sung, Kam, Tae-In, Lee, Saebom, Park, Hyejin, Oh, Yumin, Kwon, Seung-Hwan, Song, Jae-Jin, Kim, Donghoon, Kim, Hyunhee, Jhaldiyal, Aanishaa, Na, Dong Hee, Lee, Kang Choon, Park, Eun Ji, Pomper, Martin G, Pletnikova, Olga, Troncoso, Juan C, Ko, Han Seok, Dawson, Valina L, Dawson, Ted M, Lee, Seulki

Volltext

Iduna is a poly(ADP-ribose) (PAR)-dependent E3 ubiquitin ligase that regulates DNA damage von Kang, Ho Chul, Lee, Yun-Il, Shin, Joo-Ho, Andrabi, Shaida A, Chi, Zhikai, Gagné, Jean-Philippe, Lee, Yunjong, Ko, Han Seok, Lee, Byoung Dae, Poirier, Guy G, Dawson, Valina L, Dawson, Ted M

Volltext