The history and future of targeting cyclin-dependent kinases in cancer therapy von Asghar, Uzma, Witkiewicz, Agnieszka K., Turner, Nicholas C., Knudsen, Erik S.

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Metabolic Reprogramming of Pancreatic Cancer Mediated by CDK4/6 Inhibition Elicits Unique Vulnerabilities von Franco, Jorge, Balaji, Uthra, Freinkman, Elizaveta, Witkiewicz, Agnieszka K., Knudsen, Erik S.

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Retinoblastoma tumor suppressor pathway in breast cancer: prognosis, precision medicine, and therapeutic interventions von Witkiewicz, Agnieszka K, Knudsen, Erik S

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The Strange Case of CDK4/6 Inhibitors: Mechanisms, Resistance, and Combination Strategies von Knudsen, Erik S., Witkiewicz, Agnieszka K.

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Whole-exome sequencing of pancreatic cancer defines genetic diversity and therapeutic targets von Witkiewicz, Agnieszka K., McMillan, Elizabeth A., Balaji, Uthra, Baek, GuemHee, Lin, Wan-Chi, Mansour, John, Mollaee, Mehri, Wagner, Kay-Uwe, Koduru, Prasad, Yopp, Adam, Choti, Michael A., Yeo, Charles J., McCue, Peter, White, Michael A., Knudsen, Erik S.

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Tailoring to RB: tumour suppressor status and therapeutic response von Knudsen, Erik S, Knudsen, Karen E

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Oxidative stress in cancer associated fibroblasts drives tumor-stroma co-evolution: A new paradigm for understanding tumor metabolism, the field effect and genomic instability in c... von Martinez-Outschoorn, Ubaldo E., Balliet, Renee M., Rivadeneira, Dayana, Chiavarina, Barbara, Pavlides, Stephanos, Wang, Chenguang, Whitaker-Menezes, Diana, Daumer, Kristin, Lin, Zhao, Witkiewicz, Agnieszka, Flomenberg, Neal, Howell, Anthony, Pestell, Richard, Knudsen, Erik, Sotgia, Federica, Lisanti, Michael P.

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Microbial Degradation of Whole-Grain Complex Carbohydrates and Impact on Short-Chain Fatty Acids and Health von Bach Knudsen, Knud Erik

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Functional Determinants of Cell Cycle Plasticity and Sensitivity to CDK4/6 Inhibition von Kumarasamy, Vishnu, Vail, Paris, Nambiar, Ram, Witkiewicz, Agnieszka K, Knudsen, Erik S

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CDK4/6 inhibitors have potent activity in combination with pathway selective therapeutic agents in models of pancreatic cancer von Franco, Jorge, Witkiewicz, Agnieszka K, Knudsen, Erik S

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Therapeutically activating RB: reestablishing cell cycle control in endocrine therapy-resistant breast cancer von Thangavel, Chellappagounder, Dean, Jeffry L, Ertel, Adam, Knudsen, Karen E, Aldaz, C Marcelo, Witkiewicz, Agnieszka K, Clarke, Robert, Knudsen, Erik S

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Stratification of Pancreatic Ductal Adenocarcinoma: Combinatorial Genetic, Stromal, and Immunologic Markers von Knudsen, Erik S, Vail, Paris, Balaji, Uthra, Ngo, Hoai, Botros, Ihab W, Makarov, Vladimir, Riaz, Nadeem, Balachandran, Vinod, Leach, Steven, Thompson, Debrah M, Chan, Timothy A, Witkiewicz, Agnieszka K

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Impact of Diet-Modulated Butyrate Production on Intestinal Barrier Function and Inflammation von Bach Knudsen, Knud Erik, Lærke, Helle Nygaard, Hedemann, Mette Skou, Nielsen, Tina Skau, Ingerslev, Anne Krog, Gundelund Nielsen, Ditte Søvsø, Theil, Peter Kappel, Purup, Stig, Hald, Stine, Schioldan, Anne Grethe, Marco, Maria L, Gregersen, Søren, Hermansen, Kjeld

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MCT4 Defines a Glycolytic Subtype of Pancreatic Cancer with Poor Prognosis and Unique Metabolic Dependencies von Baek, GuemHee, Tse, Yan F., Hu, Zeping, Cox, Derek, Buboltz, Noah, McCue, Peter, Yeo, Charles J., White, Michael A., DeBerardinis, Ralph J., Knudsen, Erik S., Witkiewicz, Agnieszka K.

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Cancer takes many paths through G1/S von Knudsen, Erik S., Witkiewicz, Agnieszka K., Rubin, Seth M.

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Chemotherapy and CDK4/6 Inhibitors: Unexpected Bedfellows von Roberts, Patrick J, Kumarasamy, Vishnu, Witkiewicz, Agnieszka K, Knudsen, Erik S

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The meaning of p16(ink4a) expression in tumors: functional significance, clinical associations and future developments von Witkiewicz, Agnieszka K, Knudsen, Karen E, Dicker, Adam P, Knudsen, Erik S

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p27 allosterically activates cyclin-dependent kinase 4 and antagonizes palbociclib inhibition von Guiley, Keelan Z, Stevenson, Jack W, Lou, Kevin, Barkovich, Krister J, Kumarasamy, Vishnu, Wijeratne, Tilini U, Bunch, Katharine L, Tripathi, Sarvind, Knudsen, Erik S, Witkiewicz, Agnieszka K, Shokat, Kevan M, Rubin, Seth M

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Kinome-Wide RNA Interference Screen Reveals a Role for PDK1 in Acquired Resistance to CDK4/6 Inhibition in ER-Positive Breast Cancer von Jansen, Valerie M, Bhola, Neil E, Bauer, Joshua A, Formisano, Luigi, Lee, Kyung-Min, Hutchinson, Katherine E, Witkiewicz, Agnieszka K, Moore, Preston D, Estrada, Mónica Valéria, Sánchez, Violeta, Ericsson, Paula G, Sanders, Melinda E, Pohlmann, Paula R, Pishvaian, Michael J, Riddle, David A, Dugger, Teresa C, Wei, Wenyi, Knudsen, Erik S, Arteaga, Carlos L

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X‐ray free‐electron laser based dark‐field X‐ray microscopy: a simulation‐based study von Holstad, Theodor Secanell, Ræder, Trygve Magnus, Carlsen, Mads, Bergbäck Knudsen, Erik, Dresselhaus-Marais, Leora, Haldrup, Kristoffer, Simons, Hugh, Nielsen, Martin Meedom, Poulsen, Henning Friis

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