Phase III dose selection of marzeptacog alfa (activated) informed by population pharmacokinetic modeling: A novel hemostatic drug von Faraj, Alan, Knudsen, Tom, Desai, Shraddha, Neuman, Linda, Blouse, Grant E., Simonsson, Ulrika S. H.

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Model‐informed pediatric dose selection of marzeptacog alfa (activated): An exposure matching strategy von Faraj, Alan, Wijk, Rob C., Neuman, Linda, Desai, Shraddha, Blouse, Grant E., Knudsen, Tom, Simonsson, Ulrika S. H.

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Subcutaneous Marzeptacog Alfa (Activated) Versus Intravenous rFVIIa for Treatment of Episodic Bleeding in FVIII Deficient Hemophilia a Rats von Knudsen, Tom, Johansen, Peter, Reckless, Jill, Desai, Shraddha, Blouse, Grant E.

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Subcutaneous Marzeptacog Alfa (Activated) for On‐Demand Treatment of Bleeding Events in Subjects With Hemophilia A or B With Inhibitors von Faraj, Alan, Nyberg, Joakim, Blouse, Grant E., Knudsen, Tom, Simonsson, Ulrika S. H.

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The Crimson 1 Study: A Phase 3 Study to Evaluate the Efficacy and Safety of Subcutaneous Marzeptocog Alfa (activated) for on-Demand Treatment and Control of Bleeding Episodes in Su... von Neuman, Linda, Desai, Shraddha, Knudsen, Tom, Del Greco, Frank, Levy, Howard

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Phase 1/2 Study to Evaluate the Pharmacokinetics, Pharmacodynamics, Safety, and Efficacy of Marzeptacog Alfa (activated) in the Treatment of Episodic Bleeding in Subjects with Inhe... von Neuman, Linda, Desai, Shraddha, Del Greco, Frank, Knudsen, Tom, Levy, Howard

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The Combination of Marzeptacog Alfa (Activated) or Eptacog Alfa (Activated) with Emicizumab Appears Comparable As Assessed By the Thrombin Generation Test in Hemophilia a Plasma von Knudsen, Tom, Kumar, Brajesh, Del Greco, Frank, Neuman, Linda, Levy, Howard, Blouse, Grant E.

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Fast Onset of Action of Subcutaneously Administered Marzeptacog Alfa (Activated) Supports on-Demand Treatment in Hemophilia a Mice von Del Greco, Frank, Neuman, Linda, Levy, Howard, Reckless, Jill, Knudsen, Tom, Blouse, Grant E.

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Model-Based Interspecies Scaling for Predicting Human Pharmacokinetics of CB 4332, a Complement Factor I Protein von Ayoun Alsoud, Rami, Le Moan, Natacha, Holten-Andersen, Lars, Knudsen, Tom, Lennernäs, Hans, Simonsson, Ulrika S.H.

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Model-Informed Support of Dose Selection for Prophylactic Treatment with Dalcinonacog Alfa in Adult and Paediatric Hemophilia B Patients von Faraj, Alan, Le Moan, Natacha, Gorina, Eduard, Blouse, Grant E., Knudsen, Tom, Simonsson, Ulrika S. H.

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Tail Vein Transection Bleeding Model in Fully Anesthetized Hemophilia A Mice von Carol Illa, Ariadna, Baumgarten, Sarah, Danielsen, Dennis, Larsen, Karin, Elm, Torben, Johansen, Peter B., Knudsen, Tom, Lauritzen, Brian, Tranholm, Mikael, Ley, Carsten D.

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The Effect of Prophylactic Recombinant Factor IX and Glycopegylated Factor IX to Normalize Articular Wound Healing Following Hemarthrosis Examined in Hemophilia B Mice von Sun, Junjiang, Livingston, Eric, Knudsen, Tom, Monroe, Dougald M., Ezban, Mirella, Bateman, Ted, Monahan, Paul E.

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Prophylactic administration of glycoPEGylated factor IX provides protection and joint outcome superior to recombinant factor IX after induced joint bleeding von Sun, Junjiang, Livingston, Eric W., Broberg, Mie L., Johansen, Peter B., Ley, Carsten D., Knudsen, Tom, Ezban, Mirella, Bateman, Ted, Monahan, Paul E., Taves, Sarah

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Tail Vein Transection Bleeding Model in Fully Anesthetized Hemophilia A Mice von Carol Illa, Ariadna, Baumgarten, Sarah, Danielsen, Dennis, Larsen, Karin, Elm, Torben, Johansen, Peter B., Knudsen, Tom, Lauritzen, Brian, Tranholm, Mikael, Ley, Carsten D.

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Prediction of human pharmacokinetics of activated recombinant factor VII and B-domain truncated factor VIII from animal population pharmacokinetic models of haemophilia von Larsen, Malte Selch, Juul, Rasmus Vestergaard, Groth, Andreas Velsing, Simonsson, Ulrika S.H., Kristensen, Annemarie T., Knudsen, Tom, Agersø, Henrik, Kreilgaard, Mads

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Absence of functional compensation between coagulation factor VIII and plasminogen in double-knockout mice von Stagaard, Rikke, Ley, Carsten Dan, Almholt, Kasper, Olsen, Lisbeth Høier, Knudsen, Tom, Flick, Matthew J.

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Characterization of canine coagulation factor VII and its complex formation with tissue factor: canine–human cross‐species compatibility von KNUDSEN, T., KRISTENSEN, A. T., SØRENSEN, B. B., OLSEN, O. H., STENNICKE, H. R., PETERSEN, L. C.

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High expression of MHC I in the tibialis anterior muscle of a paraplegic patient von Hartkopp, Andreas, Andersen, Jesper L., Harridge, Stephen D.R., Crone, Clarissa, Gruschy‐Knudsen, Tom, Kjær, Michael, Masao, Mizuno, Ratkevicius, Aivaras, Quistorff, Bjørn, Zhou, Shi, Biering‐Sørensen, Fin

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Development of a flow cytometric assay for detection of coated platelets in dogs and evaluation of binding of coated platelets to recombinant human coagulation factor VIIa von Knudsen, Tom, Kjalke, Marianne, Tranholm, Mikael, Nichols, Timothy C, Jensen, Asger L, Kristensen, Annemarie T

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Canine specific ELISA for coagulation factor VII von Knudsen, Tom, Kjelgaard-Hansen, Mads, Tranholm, Mikael, Wiinberg, Bo, Clausen, Jes T., Hansen, Jens Jacob, Nichols, Timothy C., Kjalke, Marianne, Jensen, Asger L., Kristensen, Annemarie T.

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