Structure-Based Discovery of Novel Amide-Containing Nicotinamide Phosphoribosyltransferase (Nampt) Inhibitors von Zheng, Xiaozhang, Bauer, Paul, Baumeister, Timm, Buckmelter, Alexandre J, Caligiuri, Maureen, Clodfelter, Karl H, Han, Bingsong, Ho, Yen-Ching, Kley, Nikolai, Lin, Jian, Reynolds, Dominic J, Sharma, Geeta, Smith, Chase C, Wang, Zhongguo, Dragovich, Peter S, Gunzner-Toste, Janet, Liederer, Bianca M, Ly, Justin, O’Brien, Thomas, Oh, Angela, Wang, Leslie, Wang, Weiru, Xiao, Yang, Zak, Mark, Zhao, Guiling, Yuen, Po-wai, Bair, Kenneth W

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Structure-Based Identification of Ureas as Novel Nicotinamide Phosphoribosyltransferase (Nampt) Inhibitors von Zheng, Xiaozhang, Bauer, Paul, Baumeister, Timm, Buckmelter, Alexandre J, Caligiuri, Maureen, Clodfelter, Karl H, Han, Bingsong, Ho, Yen-Ching, Kley, Nikolai, Lin, Jian, Reynolds, Dominic J, Sharma, Geeta, Smith, Chase C, Wang, Zhongguo, Dragovich, Peter S, Oh, Angela, Wang, Weiru, Zak, Mark, Gunzner-Toste, Janet, Zhao, Guiling, Yuen, Po-wai, Bair, Kenneth W

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Induction of the growth inhibitor IGF-binding protein 3 by p53 von Buckbinder, Leonard, Talbott, Randy, Velasco-Miguel, Susana, Takenaka, Ivone, Faha, Barbara, Seizinger, Bernd R, Kley, Nikolai

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Discovery of potent and efficacious cyanoguanidine-containing nicotinamide phosphoribosyltransferase (Nampt) inhibitors von Zheng, Xiaozhang, Baumeister, Timm, Buckmelter, Alexandre J, Caligiuri, Maureen, Clodfelter, Karl H, Han, Bingsong, Ho, Yen-Ching, Kley, Nikolai, Lin, Jian, Reynolds, Dominic J, Sharma, Geeta, Smith, Chase C, Wang, Zhongguo, Dragovich, Peter S, Oh, Angela, Wang, Weiru, Zak, Mark, Wang, Yunli, Yuen, Po-Wai, Bair, Kenneth W

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PA26, a novel target of the p53 tumor suppressor and member of the GADD family of DNA damage and growth arrest inducible genes von VELASCO-MIGUEL, S, BUCKBINDER, L, JEAN, P, GELBERT, L, TALBOTT, R, LAIDLAW, J, SEIZINGER, B, KLEY, N

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p53 Regulates Insulin-Like Growth Factor-I (IGF-I) Receptor Expression and IGF-I-Induced Tyrosine Phosphorylation in an Osteosarcoma Cell Line: Interaction between p53 and Sp1 von Ohlsson, Claes, Kley, Nikolai, Werner, Haim, LeRoith, Derek

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A novel p53-inducible apoptogenic gene, PRG3, encodes a homologue of the apoptosis-inducing factor (AIF) von Ohiro, Yoichi, Garkavtsev, Igor, Kobayashi, Shinichiro, Sreekumar, Kodangattil R., Nantz, Regan, Higashikubo, Bryan T., Duffy, Shannon L., Higashikubo, Ryuji, Usheva, Anny, Gius, David, Kley, Nikolai, Horikoshi, Nobuo

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Regulation of the Sequence-specific DNA Binding Function of p53 by Protein Kinase C and Protein Phosphatases (∗) von Takenaka, Ivone, Morin, Francine, Seizinger, Bernd R., Kley, Nikolai

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Alternate choice of initiation codon produces a biologically active product of the von Hippel Lindau gene with tumor suppressor activity von BLANKENSHIP, C, NAGLICH, J. G, WHALEY, J. M, SEIZINGER, B, KLEY, N

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Abstract 629: Delivering type I interferon to dendritic cells empowers tumor eradication and immune combination treatments von Tavernier, Jan H., Cauwels, Anje, Lint, Sandra Van, Paul, Franciane, Garcin, Geneviève, Parys, Alexander Van, Kley, Nikolai, Uzé, Gilles

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The Bloom syndrome protein interacts and cooperates with p53 in regulation of transcription and cell growth control von GARKAVTSEV, Igor V, KLEY, Nikolai, GRIGORIAN, Irina A, GUDKOV, Andrei V

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Exon scanning for mutation of the NF2 gene in schwannomas von Jacoby, Lee B., MacCollin, Mia, Louls, David N., Mohney, Trina, Rublo, Mari-Paz, Pulaski, Karen, Trofatter, James A., Kley, Nikolai, Seizinger, Bernd, Ramesh, Vijaya, Gusella, James F.

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The p53 Tumor Suppressor Targets a Novel Regulator of G Protein Signaling von Buckbinder, Leonard, Velasco-Miguel, Susana, Chen, Yan, Xu, Ningzhi, Talbott, Randy, Gelbert, Larry, Gao, Jizong, Seizinger, Bernd R., Gutkind, J. Silvio, Kley, Nikolai

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Identification of amides derived from 1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid as potent inhibitors of human nicotinamide phosphoribosyltransferase (NAMPT) von Zheng, Xiaozhang, Bair, Kenneth W., Bauer, Paul, Baumeister, Timm, Bowman, Krista K., Buckmelter, Alexandre J., Caligiuri, Maureen, Clodfelter, Karl H., Feng, Yezhen, Han, Bingsong, Ho, Yen-Ching, Kley, Nikolai, Li, Hong, Liang, Xiaorong, Liederer, Bianca M., Lin, Jian, Ly, Justin, O’Brien, Thomas, Oeh, Jason, Oh, Angela, Reynolds, Dominic J., Sampath, Deepak, Sharma, Geeta, Skelton, Nicholas, Smith, Chase C., Tremayne, Jarrod, Wang, Leslie, Wang, Weiru, Wang, Zhongguo, Wu, Hongxing, Wu, Jiansheng, Xiao, Yang, Yang, Guangxing, Yuen, Po-wai, Zak, Mark, Dragovich, Peter S.

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Discovery of potent and efficacious urea-containing nicotinamide phosphoribosyltransferase (NAMPT) inhibitors with reduced CYP2C9 inhibition properties von Gunzner-Toste, Janet, Zhao, Guiling, Bauer, Paul, Baumeister, Timm, Buckmelter, Alexandre J., Caligiuri, Maureen, Clodfelter, Karl H., Fu, Bang, Han, Bingsong, Ho, Yen-Ching, Kley, Nikolai, Liang, Xiaorong, Liederer, Bianca M., Lin, Jian, Mukadam, Sophie, O’Brien, Thomas, Oh, Angela, Reynolds, Dominic J., Sharma, Geeta, Skelton, Nicholas, Smith, Chase C., Sodhi, Jasleen, Wang, Weiru, Wang, Zhongguo, Xiao, Yang, Yuen, Po-wai, Zak, Mark, Zhang, Lei, Zheng, Xiaozhang, Bair, Kenneth W., Dragovich, Peter S.

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SIRP1a TARGETED CHIMERIC PROTEINS AND USES THEREOF von KLEY, Nikolai, TAVERNIER, Jan

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TARGETED THERAPEUTIC AGENTS AND USES THEREOF von KLEY, Nikolai, TAVERNIER, Jan

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SIRP1α targeted chimeric proteins and uses thereof von Tavernier, Jan, Kley, Nikolai

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TARGETED THERAPEUTIC AGENTS AND USES THEREOF von KLEY, Nikolai, TAVERNIER, Jan

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The von Hippel-Lindau Tumor Suppressor Protein Is Required for Proper Assembly of an Extracellular Fibronectin Matrix von Ohh, Michael, Yauch, Robert L., Lonergan, Kim M., Whaley, Jean M., Stemmer-Rachamimov, Anat O., Louis, David N., Gavin, Brian J., Kley, Nikolai, Kaelin, William G., Iliopoulos, Othon

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