Generation and characterization of iPSC-derived renal proximal tubule-like cells with extended stability von Chandrasekaran, Vidya, Carta, Giada, da Costa Pereira, Daniel, Gupta, Rajinder, Murphy, Cormac, Feifel, Elisabeth, Kern, Georg, Lechner, Judith, Cavallo, Anna Lina, Gupta, Shailesh, Caiment, Florian, Kleinjans, Jos C. S., Gstraunthaler, Gerhard, Jennings, Paul, Wilmes, Anja

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Comparison of statistical methods and the use of quality control samples for batch effect correction in human transcriptome data von Espín-Pérez, Almudena, Portier, Chris, Chadeau-Hyam, Marc, van Veldhoven, Karin, Kleinjans, Jos C S, de Kok, Theo M C M

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Classification of Hepatotoxicants Using HepG2 Cells: A Proof of Principle Study von Van den Hof, Wim F. P. M, Coonen, Maarten L. J, van Herwijnen, Marcel, Brauers, Karen, Wodzig, Will K. W. H, van Delft, Joost H. M, Kleinjans, Jos C. S

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Application of high-throughput sequencing to circulating microRNAs reveals novel biomarkers for drug-induced liver injury von Krauskopf, Julian, Caiment, Florian, Claessen, Sandra M, Johnson, Kent J, Warner, Roscoe L, Schomaker, Shelli J, Burt, Deborah A, Aubrecht, Jiri, Kleinjans, Jos C

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New insights into the mechanisms underlying 5-fluorouracil-induced intestinal toxicity based on transcriptomic and metabolomic responses in human intestinal organoids von Rodrigues, Daniela, de Souza, Terezinha, Coyle, Luke, Di Piazza, Matteo, Herpers, Bram, Ferreira, Sofia, Zhang, Mian, Vappiani, Johanna, Sévin, Daniel C., Gabor, Attila, Lynch, Anthony, Chung, Seung-Wook, Saez-Rodriguez, Julio, Jennen, Danyel G. J., Kleinjans, Jos C. S., de Kok, Theo M.

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Short-term exposure to traffic-related air pollution reveals a compound-specific circulating miRNA profile indicating multiple disease risks von Krauskopf, Julian, van Veldhoven, Karin, Chadeau-Hyam, Marc, Vermeulen, Roel, Carrasco-Turigas, Glòria, Nieuwenhuijsen, Mark, Vineis, Paolo, de Kok, Theo M., Kleinjans, Jos C.

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Rationale for Environmental Hygiene towards global protection of fetuses and young children from adverse lifestyle factors von Bourguignon, Jean-Pierre, Parent, Anne-Simone, Kleinjans, Jos C S, Nawrot, Tim S, Schoeters, Greet, Van Larebeke, Nicolas

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Serum microRNA signatures as "liquid biopsies" for interrogating hepatotoxic mechanisms and liver pathogenesis in human von Krauskopf, Julian, de Kok, Theo M, Schomaker, Shelli J, Gosink, Mark, Burt, Deborah A, Chandler, Patricia, Warner, Roscoe L, Johnson, Kent J, Caiment, Florian, Kleinjans, Jos C, Aubrecht, Jiri

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Nuclear and Mitochondrial DNA Methylation Patterns Induced by Valproic Acid in Human Hepatocytes von Wolters, Jarno E. J, van Breda, Simone G. J, Caiment, Florian, Claessen, Sandra M, de Kok, Theo M. C. M, Kleinjans, Jos C. S

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MicroRNA profile for health risk assessment: Environmental exposure to persistent organic pollutants strongly affects the human blood microRNA machinery von Krauskopf, Julian, de Kok, Theo M., Hebels, Dennie G., Bergdahl, Ingvar A., Johansson, Anders, Spaeth, Florentin, Kiviranta, Hannu, Rantakokko, Panu, Kyrtopoulos, Soterios A., Kleinjans, Jos C.

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Performance in omics analyses of blood samples in long-term storage: opportunities for the exploitation of existing biobanks in environmental health research von Hebels, Dennie G A J, Georgiadis, Panagiotis, Keun, Hector C, Athersuch, Toby J, Vineis, Paolo, Vermeulen, Roel, Portengen, Lützen, Bergdahl, Ingvar A, Hallmans, Göran, Palli, Domenico, Bendinelli, Benedetta, Krogh, Vittorio, Tumino, Rosario, Sacerdote, Carlotta, Panico, Salvatore, Kleinjans, Jos C S, de Kok, Theo M C M, Smith, Martyn T, Kyrtopoulos, Soterios A

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Unravelling Mechanisms of Doxorubicin-Induced Toxicity in 3D Human Intestinal Organoids von Rodrigues, Daniela, Coyle, Luke, Füzi, Barbara, Ferreira, Sofia, Jo, Heeseung, Herpers, Bram, Chung, Seung-Wook, Fisher, Ciarán, Kleinjans, Jos C S, Jennen, Danyel, de Kok, Theo M

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Aflatoxin B1 induces persistent epigenomic effects in primary human hepatocytes associated with hepatocellular carcinoma von Rieswijk, Linda, Claessen, Sandra M.H, Bekers, Otto, Herwijnen, Marcel van, Theunissen, Daniël H.J, Jennen, Danyel G.J, de Kok, Theo M.C.M, Kleinjans, Jos C.S, van Breda, Simone G.J

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Comparison of HepG2 and HepaRG by Whole-Genome Gene Expression Analysis for the Purpose of Chemical Hazard Identification von Jennen, Danyel G. J., Magkoufopoulou, Christina, Ketelslegers, Hans B., van Herwijnen, Marcel H. M., Kleinjans, Jos C. S., van Delft, Joost H. M.

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Epigenetic mechanisms underlying arsenic-associated lung carcinogenesis von van Breda, Simone G. J., Claessen, Sandra M. H., Lo, Ken, van Herwijnen, Marcel, Brauers, Karen J. J., Lisanti, Sofia, Theunissen, Daniël H. J., Jennen, Danyel G. J., Gaj, Stan, de Kok, Theo M. C. M., Kleinjans, Jos C. S.

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Increased mitochondrial ROS formation by acetaminophen in human hepatic cells is associated with gene expression changes suggesting disruption of the mitochondrial electron transpo... von Jiang, Jian, Briedé, Jacob J., Jennen, Danyel G.J., Van Summeren, Anke, Saritas-Brauers, Karen, Schaart, Gert, Kleinjans, Jos C.S., de Kok, Theo M.C.M.

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Toxicogenomics directory of chemically exposed human hepatocytes von Grinberg, Marianna, Stöber, Regina M., Edlund, Karolina, Rempel, Eugen, Godoy, Patricio, Reif, Raymond, Widera, Agata, Madjar, Katrin, Schmidt-Heck, Wolfgang, Marchan, Rosemarie, Sachinidis, Agapios, Spitkovsky, Dimitry, Hescheler, Jürgen, Carmo, Helena, Arbo, Marcelo D., van de Water, Bob, Wink, Steven, Vinken, Mathieu, Rogiers, Vera, Escher, Sylvia, Hardy, Barry, Mitic, Dragana, Myatt, Glenn, Waldmann, Tanja, Mardinoglu, Adil, Damm, Georg, Seehofer, Daniel, Nüssler, Andreas, Weiss, Thomas S., Oberemm, Axel, Lampen, Alfons, Schaap, Mirjam M., Luijten, Mirjam, van Steeg, Harry, Thasler, Wolfgang E., Kleinjans, Jos C. S., Stierum, Rob H., Leist, Marcel, Rahnenführer, Jörg, Hengstler, Jan G.

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Application of toxicogenomics to study mechanisms of genotoxicity and carcinogenicity von Ellinger-Ziegelbauer, Heidrun, Aubrecht, Jiri, Kleinjans, Jos C., Ahr, Hans-Juergen

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A Transcriptomic Approach to Elucidate the Mechanisms of Gefitinib-Induced Toxicity in Healthy Human Intestinal Organoids von Rodrigues, Daniela, Herpers, Bram, Ferreira, Sofia, Jo, Heeseung, Fisher, Ciarán, Coyle, Luke, Chung, Seung-Wook, Kleinjans, Jos C S, Jennen, Danyel G J, de Kok, Theo M

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Proteomics investigations of drug-induced hepatotoxicity in HepG2 cells von Van Summeren, Anke, Renes, Johan, Bouwman, Freek G, Noben, Jean-Paul, van Delft, Joost H M, Kleinjans, Jos C S, Mariman, Edwin C M

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