Generation and characterization of iPSC-derived renal proximal tubule-like cells with extended stability von Chandrasekaran, Vidya, Carta, Giada, da Costa Pereira, Daniel, Gupta, Rajinder, Murphy, Cormac, Feifel, Elisabeth, Kern, Georg, Lechner, Judith, Cavallo, Anna Lina, Gupta, Shailesh, Caiment, Florian, Kleinjans, Jos C. S., Gstraunthaler, Gerhard, Jennings, Paul, Wilmes, Anja

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Performance in omics analyses of blood samples in long-term storage: opportunities for the exploitation of existing biobanks in environmental health research von Hebels, Dennie G A J, Georgiadis, Panagiotis, Keun, Hector C, Athersuch, Toby J, Vineis, Paolo, Vermeulen, Roel, Portengen, Lützen, Bergdahl, Ingvar A, Hallmans, Göran, Palli, Domenico, Bendinelli, Benedetta, Krogh, Vittorio, Tumino, Rosario, Sacerdote, Carlotta, Panico, Salvatore, Kleinjans, Jos C S, de Kok, Theo M C M, Smith, Martyn T, Kyrtopoulos, Soterios A

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Aflatoxin B1 induces persistent epigenomic effects in primary human hepatocytes associated with hepatocellular carcinoma von Rieswijk, Linda, Claessen, Sandra M.H, Bekers, Otto, Herwijnen, Marcel van, Theunissen, Daniël H.J, Jennen, Danyel G.J, de Kok, Theo M.C.M, Kleinjans, Jos C.S, van Breda, Simone G.J

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Comparison of statistical methods and the use of quality control samples for batch effect correction in human transcriptome data von Espín-Pérez, Almudena, Portier, Chris, Chadeau-Hyam, Marc, van Veldhoven, Karin, Kleinjans, Jos C S, de Kok, Theo M C M

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Transcriptomic and metabolomic data integration von Cavill, Rachel, Jennen, Danyel, Kleinjans, Jos, Briedé, Jacob Jan

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Classification of Hepatotoxicants Using HepG2 Cells: A Proof of Principle Study von Van den Hof, Wim F. P. M, Coonen, Maarten L. J, van Herwijnen, Marcel, Brauers, Karen, Wodzig, Will K. W. H, van Delft, Joost H. M, Kleinjans, Jos C. S

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New insights into the mechanisms underlying 5-fluorouracil-induced intestinal toxicity based on transcriptomic and metabolomic responses in human intestinal organoids von Rodrigues, Daniela, de Souza, Terezinha, Coyle, Luke, Di Piazza, Matteo, Herpers, Bram, Ferreira, Sofia, Zhang, Mian, Vappiani, Johanna, Sévin, Daniel C., Gabor, Attila, Lynch, Anthony, Chung, Seung-Wook, Saez-Rodriguez, Julio, Jennen, Danyel G. J., Kleinjans, Jos C. S., de Kok, Theo M.

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Epigenome-wide association study of adiposity and future risk of obesity-related diseases von Campanella, Gianluca, Gunter, Marc J., Polidoro, Silvia, Krogh, Vittorio, Palli, Domenico, Panico, Salvatore, Sacerdote, Carlotta, Tumino, Rosario, Fiorito, Giovanni, Guarrera, Simonetta, Iacoviello, Licia, Bergdahl, Ingvar A., Melin, Beatrice, Lenner, Per, de Kok, Theo M. C. M., Georgiadis, Panagiotis, Kleinjans, Jos C. S., Kyrtopoulos, Soterios A., Bueno-de-Mesquita, H. Bas, Lillycrop, Karen A., May, Anne M., Onland-Moret, N. Charlotte, Murray, Robert, Riboli, Elio, Verschuren, Monique, Lund, Eiliv, Mode, Nicolle, Sandanger, Torkjel M., Fiano, Valentina, Trevisan, Morena, Matullo, Giuseppe, Froguel, Philippe, Elliott, Paul, Vineis, Paolo, Chadeau-Hyam, Marc

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Rationale for Environmental Hygiene towards global protection of fetuses and young children from adverse lifestyle factors von Bourguignon, Jean-Pierre, Parent, Anne-Simone, Kleinjans, Jos C S, Nawrot, Tim S, Schoeters, Greet, Van Larebeke, Nicolas

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Toxicogenomics directory of chemically exposed human hepatocytes von Grinberg, Marianna, Stöber, Regina M., Edlund, Karolina, Rempel, Eugen, Godoy, Patricio, Reif, Raymond, Widera, Agata, Madjar, Katrin, Schmidt-Heck, Wolfgang, Marchan, Rosemarie, Sachinidis, Agapios, Spitkovsky, Dimitry, Hescheler, Jürgen, Carmo, Helena, Arbo, Marcelo D., van de Water, Bob, Wink, Steven, Vinken, Mathieu, Rogiers, Vera, Escher, Sylvia, Hardy, Barry, Mitic, Dragana, Myatt, Glenn, Waldmann, Tanja, Mardinoglu, Adil, Damm, Georg, Seehofer, Daniel, Nüssler, Andreas, Weiss, Thomas S., Oberemm, Axel, Lampen, Alfons, Schaap, Mirjam M., Luijten, Mirjam, van Steeg, Harry, Thasler, Wolfgang E., Kleinjans, Jos C. S., Stierum, Rob H., Leist, Marcel, Rahnenführer, Jörg, Hengstler, Jan G.

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Increased mitochondrial ROS formation by acetaminophen in human hepatic cells is associated with gene expression changes suggesting disruption of the mitochondrial electron transpo... von Jiang, Jian, Briedé, Jacob J., Jennen, Danyel G.J., Van Summeren, Anke, Saritas-Brauers, Karen, Schaart, Gert, Kleinjans, Jos C.S., de Kok, Theo M.C.M.

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Integrating SNPs-based genetic risk factor with blood epigenomic response of differentially arsenic-exposed rural subjects reveals disease-associated signaling pathways von Rehman, Muhammad Yasir Abdur, Briedé, Jacco Jan, van Herwijnen, Marcel, Krauskopf, Julian, Jennen, Danyel G.J., Malik, Riffat Naseem, Kleinjans, Jos C.S.

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Unravelling Mechanisms of Doxorubicin-Induced Toxicity in 3D Human Intestinal Organoids von Rodrigues, Daniela, Coyle, Luke, Füzi, Barbara, Ferreira, Sofia, Jo, Heeseung, Herpers, Bram, Chung, Seung-Wook, Fisher, Ciarán, Kleinjans, Jos C S, Jennen, Danyel, de Kok, Theo M

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Acute changes in DNA methylation in relation to 24 h personal air pollution exposure measurements: A panel study in four European countries von Mostafavi, Nahid, Vermeulen, Roel, Ghantous, Akram, Hoek, Gerard, Probst-Hensch, Nicole, Herceg, Zdenko, Tarallo, Sonia, Naccarati, Alessio, Kleinjans, Jos C.S., Imboden, Medea, Jeong, Ayoung, Morley, David, Amaral, Andre F.S., van Nunen, Erik, Gulliver, John, Chadeau-Hyam, Marc, Vineis, Paolo, Vlaanderen, Jelle

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Short-term transcriptome and microRNAs responses to exposure to different air pollutants in two population studies von Espín-Pérez, Almudena, Krauskopf, Julian, Chadeau-Hyam, Marc, van Veldhoven, Karin, Chung, Fan, Cullinan, Paul, Piepers, Jolanda, van Herwijnen, Marcel, Kubesch, Nadine, Carrasco-Turigas, Glòria, Nieuwenhuijsen, Mark, Vineis, Paolo, Kleinjans, Jos C.S., de Kok, Theo M.C.M.

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Small RNA Sequencing of Aqueous Humor and Plasma in Patients With Primary Open-Angle Glaucoma von Hubens, Wouter H. G., Krauskopf, Julian, Beckers, Henny J. M., Kleinjans, Jos C. S., Webers, Carroll A. B., Gorgels, Theo G. M. F.

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Identifying novel transcript biomarkers for hepatocellular carcinoma (HCC) using RNA-Seq datasets and machine learning von Gupta, Rajinder, Kleinjans, Jos, Caiment, Florian

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Comparing in vitro human liver models to in vivo human liver using RNA-Seq von Gupta, Rajinder, Schrooders, Yannick, Hauser, Duncan, van Herwijnen, Marcel, Albrecht, Wiebke, ter Braak, Bas, Brecklinghaus, Tim, Castell, Jose V., Elenschneider, Leroy, Escher, Sylvia, Guye, Patrick, Hengstler, Jan G., Ghallab, Ahmed, Hansen, Tanja, Leist, Marcel, Maclennan, Richard, Moritz, Wolfgang, Tolosa, Laia, Tricot, Tine, Verfaillie, Catherine, Walker, Paul, van de Water, Bob, Kleinjans, Jos, Caiment, Florian

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Comparison of HepG2 and HepaRG by Whole-Genome Gene Expression Analysis for the Purpose of Chemical Hazard Identification von Jennen, Danyel G. J., Magkoufopoulou, Christina, Ketelslegers, Hans B., van Herwijnen, Marcel H. M., Kleinjans, Jos C. S., van Delft, Joost H. M.

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Nuclear and Mitochondrial DNA Methylation Patterns Induced by Valproic Acid in Human Hepatocytes von Wolters, Jarno E. J, van Breda, Simone G. J, Caiment, Florian, Claessen, Sandra M, de Kok, Theo M. C. M, Kleinjans, Jos C. S

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