Molecular and cellular mechanisms of tooth development, homeostasis and repair von Yu, Tingsheng, Klein, Ophir D

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Activation of fetal-like molecular programs during regeneration in the intestine and beyond von Viragova, Sara, Li, Dong, Klein, Ophir D.

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Diverse progenitor cells preserve salivary gland ductal architecture after radiation-induced damage von May, Alison J, Cruz-Pacheco, Noel, Emmerson, Elaine, Gaylord, Eliza A, Seidel, Kerstin, Nathan, Sara, Muench, Marcus O, Klein, Ophir D, Knox, Sarah M

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Opposing Activities of Notch and Wnt Signaling Regulate Intestinal Stem Cells and Gut Homeostasis von Tian, Hua, Biehs, Brian, Chiu, Cecilia, Siebel, Christian W., Wu, Yan, Costa, Mike, de Sauvage, Frederic J., Klein, Ophir D.

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Sox2+ Stem Cells Contribute to All Epithelial Lineages of the Tooth via Sfrp5+ Progenitors von Juuri, Emma, Saito, Kan, Ahtiainen, Laura, Seidel, Kerstin, Tummers, Mark, Hochedlinger, Konrad, Klein, Ophir D., Thesleff, Irma, Michon, Frederic

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Editorial overview: How to generate and maintain organs–organoids, regeneration, and beyond von Klein, Ophir D., Nishinakamura, Ryuichi

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Harnessing synthetic biology to engineer organoids and tissues von Trentesaux, Coralie, Yamada, Toshimichi, Klein, Ophir D, Lim, Wendell A

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In vitro patterning of pluripotent stem cell-derived intestine recapitulates in vivo human development von Tsai, Yu-Hwai, Nattiv, Roy, Dedhia, Priya H, Nagy, Melinda S, Chin, Alana M, Thomson, Matthew, Klein, Ophir D, Spence, Jason R

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Feedback regulation of RTK signaling in development von Neben, Cynthia L., Lo, Megan, Jura, Natalia, Klein, Ophir D.

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Secretion of Shh by a Neurovascular Bundle Niche Supports Mesenchymal Stem Cell Homeostasis in the Adult Mouse Incisor von Zhao, Hu, Feng, Jifan, Seidel, Kerstin, Shi, Songtao, Klein, Ophir, Sharpe, Paul, Chai, Yang

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Engineering synthetic morphogen systems that can program multicellular patterning von Toda, Satoshi, McKeithan, Wesley L, Hakkinen, Teemu J, Lopez, Pilar, Klein, Ophir D, Lim, Wendell A

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Parasitic helminths induce fetal-like reversion in the intestinal stem cell niche von Nusse, Ysbrand M., Savage, Adam K., Marangoni, Pauline, Rosendahl-Huber, Axel K. M., Landman, Tyler A., de Sauvage, Frederic J., Locksley, Richard M., Klein, Ophir D.

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Dental cell type atlas reveals stem and differentiated cell types in mouse and human teeth von Krivanek, Jan, Soldatov, Ruslan A., Kastriti, Maria Eleni, Chontorotzea, Tatiana, Herdina, Anna Nele, Petersen, Julian, Szarowska, Bara, Landova, Marie, Matejova, Veronika Kovar, Holla, Lydie Izakovicova, Kuchler, Ulrike, Zdrilic, Ivana Vidovic, Vijaykumar, Anushree, Balic, Anamaria, Marangoni, Pauline, Klein, Ophir D., Neves, Vitor C. M., Yianni, Val, Sharpe, Paul T., Harkany, Tibor, Metscher, Brian D., Bajénoff, Marc, Mina, Mina, Fried, Kaj, Kharchenko, Peter V., Adameyko, Igor

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Precise modulation of transcription factor levels identifies features underlying dosage sensitivity von Naqvi, Sahin, Kim, Seungsoo, Hoskens, Hanne, Matthews, Harold S., Spritz, Richard A., Klein, Ophir D., Hallgrímsson, Benedikt, Swigut, Tomek, Claes, Peter, Pritchard, Jonathan K., Wysocka, Joanna

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A large pool of actively cycling progenitors orchestrates self-renewal and injury repair of an ectodermal appendage von Sharir, Amnon, Marangoni, Pauline, Zilionis, Rapolas, Wan, Mian, Wald, Tomas, Hu, Jimmy K., Kawaguchi, Kyogo, Castillo-Azofeifa, David, Epstein, Leo, Harrington, Kyle, Pagella, Pierfrancesco, Mitsiadis, Thimios, Siebel, Christian W., Klein, Allon M., Klein, Ophir D.

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Myosin II mediates Shh signals to shape dental epithelia via control of cell adhesion and movement von Du, Wei, Verma, Adya, Ye, Qianlin, Du, Wen, Lin, Sandy, Yamanaka, Atsushi, Klein, Ophir D, Hu, Jimmy K

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In vitro generation of human pluripotent stem cell derived lung organoids von Dye, Briana R, Hill, David R, Ferguson, Michael A H, Tsai, Yu-Hwai, Nagy, Melinda S, Dyal, Rachel, Wells, James M, Mayhew, Christopher N, Nattiv, Roy, Klein, Ophir D, White, Eric S, Deutsch, Gail H, Spence, Jason R

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A reserve stem cell population in small intestine renders Lgr5-positive cells dispensable von Tian, Hua, Biehs, Brian, Warming, Søren, Leong, Kevin G., Rangell, Linda, Klein, Ophir D., de Sauvage, Frederic J.

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Inhibition of Wnt signaling by Wise (Sostdc1) and negative feedback from Shh controls tooth number and patterning von Ahn, Youngwook, Sanderson, Brian W, Klein, Ophir D, Krumlauf, Robb

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Quantitative Clonal Analysis and Single-Cell Transcriptomics Reveal Division Kinetics, Hierarchy, and Fate of Oral Epithelial Progenitor Cells von Jones, Kyle B., Furukawa, Sachiko, Marangoni, Pauline, Ma, Hongfang, Pinkard, Henry, D’Urso, Rebecca, Zilionis, Rapolas, Klein, Allon M., Klein, Ophir D.

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