Phyllodes Tumor of the Breast: Histopathologic Features, Differential Diagnosis, and Molecular/Genetic Updates von Zhang, Yanhong, Kleer, Celina G

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Poised Chromatin at the ZEB1 Promoter Enables Breast Cancer Cell Plasticity and Enhances Tumorigenicity von Chaffer, Christine L., Marjanovic, Nemanja D., Lee, Tony, Bell, George, Kleer, Celina G., Reinhardt, Ferenc, D’Alessio, Ana C., Young, Richard A., Weinberg, Robert A.

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Repression of E-cadherin by the polycomb group protein EZH2 in cancer von Cao, Q, Yu, J, Dhanasekaran, S M, Kim, J H, Mani, R-S, Tomlins, S A, Mehra, R, Laxman, B, Cao, X, Kleer, C G, Varambally, S, Chinnaiyan, A M

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Discoidin domain receptor tyrosine kinases: new players in cancer progression von Valiathan, Rajeshwari R., Marco, Marta, Leitinger, Birgit, Kleer, Celina G., Fridman, Rafael

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ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome von Ginestier, Christophe, Hur, Min Hee, Charafe-Jauffret, Emmanuelle, Monville, Florence, Dutcher, Julie, Brown, Marty, Jacquemier, Jocelyne, Viens, Patrice, Kleer, Celina G, Liu, Suling, Schott, Anne, Hayes, Dan, Birnbaum, Daniel, Wicha, Max S, Dontu, Gabriela

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Breast Cancer Stem Cells Are Regulated by Mesenchymal Stem Cells through Cytokine Networks von SULING LIU, GINESTIER, Christophe, JUNG, Younghun, DONTU, Gabriela, TAICHMAN, Russell, WICHA, Max S, OU, Sing J, CLOUTHIER, Shawn G, PATEL, Shivani H, MONVILLE, Florence, KORKAYA, Hasan, HEATH, Amber, DUTCHER, Julie, KLEER, Celina G

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Canonical Wnt signaling regulates Slug activity and links epithelial–mesenchymal transition with epigenetic Breast Cancer 1, Early Onset (BRCA1) repression von Wu, Zhao-Qiu, Li, Xiao-Yan, Hu, Casey Yuexian, Ford, Michael, Kleer, Celina G, Weiss, Stephen J

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EZH2 expands breast stem cells through activation of NOTCH1 signaling von Gonzalez, Maria E., Moore, Heather M., Li, Xin, Toy, Kathy A., Huang, Wei, Sabel, Michael S., Kidwell, Kelley M., Kleer, Celina G.

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Quantitative proteomic landscape of metaplastic breast carcinoma pathological subtypes and their relationship to triple-negative tumors von Djomehri, Sabra I., Gonzalez, Maria E., da Veiga Leprevost, Felipe, Tekula, Shilpa R., Chang, Hui-Yin, White, Marissa J., Cimino-Mathews, Ashley, Burman, Boris, Basrur, Venkatesha, Argani, Pedram, Nesvizhskii, Alexey I., Kleer, Celina G.

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p38-mediated phosphorylation at T367 induces EZH2 cytoplasmic localization to promote breast cancer metastasis von Anwar, Talha, Arellano-Garcia, Caroline, Ropa, James, Chen, Yu-Chih, Kim, Hong Sun, Yoon, Euisik, Grigsby, Sierrah, Basrur, Venkatesha, Nesvizhskii, Alexey I., Muntean, Andrew, Gonzalez, Maria E., Kidwell, Kelley M., Nikolovska-Coleska, Zaneta, Kleer, Celina G.

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Spatiotemporal analysis of glioma heterogeneity reveals COL1A1 as an actionable target to disrupt tumor progression von Comba, Andrea, Faisal, Syed M., Dunn, Patrick J., Argento, Anna E., Hollon, Todd C., Al-Holou, Wajd N., Varela, Maria Luisa, Zamler, Daniel B., Quass, Gunnar L., Apostolides, Pierre F., Abel, Clifford, Brown, Christine E., Kish, Phillip E., Kahana, Alon, Kleer, Celina G., Motsch, Sebastien, Castro, Maria G., Lowenstein, Pedro R.

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EZH2 Is a Marker of Aggressive Breast Cancer and Promotes Neoplastic Transformation of Breast Epithelial Cells von Kleer, Celina G., Cao, Qi, Varambally, Sooryanarayana, Shen, Ronglai, Ota, Ichiro, Tomlins, Scott A., Ghosh, Debashis, Richard G. A. B. Sewalt, Otte, Arie P., Hayes, Daniel F., Sabel, Michael S., Livant, Donna, Weiss, Stephen J., Rubin, Mark A., Chinnaiyan, Arul M.

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An Absence of Stromal Caveolin-1 Expression Predicts Early Tumor Recurrence and Poor Clinical Outcome in Human Breast Cancers von Witkiewicz, Agnieszka K, Dasgupta, Abhijit, Sotgia, Federica, Mercier, Isabelle, Pestell, Richard G, Sabel, Michael, Kleer, Celina G, Brody, Jonathan R, Lisanti, Michael P

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HER2 Drives Luminal Breast Cancer Stem Cells in the Absence of HER2 Amplification: Implications for Efficacy of Adjuvant Trastuzumab von ITHIMAKIN, Suthinee, DAY, Kathleen C, HALL, Christopher L, PALANISAMY, Nallasivam, HEATH, Amber N, TAWAKKOL, Nader, LUTHER, Tahra K, CLOUTHIER, Shawn G, CHADWICK, Whitney A, DAY, Mark L, KLEER, Celina G, THOMAS, Dafydd G, MALIK, Fayaz, HAYES, Daniel F, KORKAYA, Hasan, WICHA, Max S, QIN ZEN, DAWSEY, Scott J, BERSANO-BEGEY, Tom F, QURAISHI, Ahmed A, IGNATOSKI, Kathleen Woods, DAIGNAULT, Stephanie, DAVIS, April

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Downregulation of EZH2 decreases growth of estrogen receptor-negative invasive breast carcinoma and requires BRCA1 von Gonzalez, M E, Li, X, Toy, K, DuPrie, M, Ventura, A C, Banerjee, M, Ljungman, M, Merajver, S D, Kleer, C G

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Metaplastic breast carcinomas are enriched in markers of tumor-initiating cells and epithelial to mesenchymal transition von Zhang, Yanhong, Toy, Kathy A, Kleer, Celina G

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Mesenchymal Stem/Stromal Cell Engulfment Reveals Metastatic Advantage in Breast Cancer von Chen, Yu-Chih, Gonzalez, Maria E., Burman, Boris, Zhao, Xintao, Anwar, Talha, Tran, Mai, Medhora, Natasha, Hiziroglu, Ayse B., Lee, Woncheol, Cheng, Yu-Heng, Choi, Yehyun, Yoon, Euisik, Kleer, Celina G.

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CDK2-mediated site-specific phosphorylation of EZH2 drives and maintains triple-negative breast cancer von Nie, Lei, Wei, Yongkun, Zhang, Fei, Hsu, Yi-Hsin, Chan, Li-Chuan, Xia, Weiya, Ke, Baozhen, Zhu, Cihui, Deng, Rong, Tang, Jun, Yao, Jun, Chu, Yu-Yi, Zhao, Xixi, Han, Ye, Hou, Junwei, Huo, Longfei, Ko, How-Wen, Lin, Wan-Chi, Yamaguchi, Hirohito, Hsu, Jung-Mao, Yang, Yi, Pan, Dean N., Hsu, Jennifer L., Kleer, Celina G., Davidson, Nancy E., Hortobagyi, Gabriel N., Hung, Mien-Chie

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BRCA1 regulates human mammary stem/progenitor cell fate von Liu, Suling, Ginestier, Christophe, Charafe-Jauffret, Emmanuelle, Foco, Hailey, Kleer, Celina G, Merajver, Sofia D, Dontu, Gabriela, Wicha, Max S

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Functionally recurrent rearrangements of the MAST kinase and Notch gene families in breast cancer von Robinson, Dan R, Kalyana-Sundaram, Shanker, Wu, Yi-Mi, Shankar, Sunita, Cao, Xuhong, Ateeq, Bushra, Asangani, Irfan A, Iyer, Matthew, Maher, Christopher A, Grasso, Catherine S, Lonigro, Robert J, Quist, Michael, Siddiqui, Javed, Mehra, Rohit, Jing, Xiaojun, Giordano, Thomas J, Sabel, Michael S, Kleer, Celina G, Palanisamy, Nallasivam, Natrajan, Rachael, Lambros, Maryou B, Reis-Filho, Jorge S, Kumar-Sinha, Chandan, Chinnaiyan, Arul M

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