Tissue inhibitor of metalloproteinases (TIMP)‐1 creates a premetastatic niche in the liver through SDF‐1/CXCR4‐dependent neutrophil recruitment in mice von Seubert, Bastian, Grünwald, Barbara, Kobuch, Julia, Cui, Haissi, Schelter, Florian, Schaten, Susanne, Siveke, Jens T., Lim, Ngee H., Nagase, Hideaki, Simonavicius, Nicole, Heikenwalder, Mathias, Reinheckel, Thomas, Sleeman, Jonathan P., Janssen, Klaus‐Peter, Knolle, Percy A., Krüger, Achim

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Novel role for CRK adaptor proteins as essential components of SRC/FAK signaling for epithelial–mesenchymal transition and colorectal cancer aggressiveness von Franke, Fabian C., Slusarenko, Benjamin O., Engleitner, Thomas, Johannes, Widya, Laschinger, Melanie, Rad, Roland, Nitsche, Ulrich, Janssen, Klaus‐Peter

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High-mass-resolution MALDI mass spectrometry imaging of metabolites from formalin-fixed paraffin-embedded tissue von Ly, Alice, Buck, Achim, Balluff, Benjamin, Sun, Na, Gorzolka, Karin, Feuchtinger, Annette, Janssen, Klaus-Peter, Kuppen, Peter J K, van de Velde, Cornelis J H, Weirich, Gregor, Erlmeier, Franziska, Langer, Rupert, Aubele, Michaela, Zitzelsberger, Horst, McDonnell, Liam, Aichler, Michaela, Walch, Axel

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Mucinous and Signet-Ring Cell Colorectal Cancers Differ from Classical Adenocarcinomas in Tumor Biology and Prognosis von Nitsche, Ulrich, Zimmermann, Anina, Späth, Christoph, Müller, Tara, Maak, Matthias, Schuster, Tibor, Slotta-Huspenina, Julia, Käser, Samuel A, Michalski, Christoph W, Janssen, Klaus-Peter, Friess, Helmut, Rosenberg, Robert, Bader, Franz G

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Mitochondrial function controls intestinal epithelial stemness and proliferation von Berger, Emanuel, Rath, Eva, Yuan, Detian, Waldschmitt, Nadine, Khaloian, Sevana, Allgäuer, Michael, Staszewski, Ori, Lobner, Elena M., Schöttl, Theresa, Giesbertz, Pieter, Coleman, Olivia I., Prinz, Marco, Weber, Achim, Gerhard, Markus, Klingenspor, Martin, Janssen, Klaus-Peter, Heikenwalder, Mathias, Haller, Dirk

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The emerging and diverse roles of the SLy/SASH1‐protein family in health and disease—Overview of three multifunctional proteins von Jaufmann, Jennifer, Franke, Fabian Christoph, Sperlich, Andreas, Blumendeller, Carolin, Kloos, Isabel, Schneider, Barbara, Sasaki, Daisuke, Janssen, Klaus‐Peter, Beer‐Hammer, Sandra

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High-resolution MALDI-FT-ICR MS imaging for the analysis of metabolites from formalin-fixed, paraffin-embedded clinical tissue samples von Buck, Achim, Ly, Alice, Balluff, Benjamin, Sun, Na, Gorzolka, Karin, Feuchtinger, Annette, Janssen, Klaus-Peter, Kuppen, Peter JK, van de Velde, Cornelis JH, Weirich, Gregor, Erlmeier, Franziska, Langer, Rupert, Aubele, Michaela, Zitzelsberger, Horst, Aichler, Michaela, Walch, Axel

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Gut bacterial dysbiosis and instability is associated with the onset of complications and mortality in COVID-19 von Schult, David, Reitmeier, Sandra, Koyumdzhieva, Plamena, Lahmer, Tobias, Middelhoff, Moritz, Erber, Johanna, Schneider, Jochen, Kager, Juliane, Frolova, Marina, Horstmann, Julia, Fricke, Lisa, Steiger, Katja, Jesinghaus, Moritz, Janssen, Klaus-Peter, Protzer, Ulrike, Neuhaus, Klaus, Schmid, Roland M., Haller, Dirk, Quante, Michael

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Suppression of mutant Kirsten-RAS (KRASG12D)-driven pancreatic carcinogenesis by dual-specificity MAP kinase phosphatases 5 and 6 von Kidger, Andrew M., Saville, Mark K., Rushworth, Linda K., Davidson, Jane, Stellzig, Julia, Ono, Motoharu, Kuebelsbeck, Ludwig A., Janssen, Klaus-Peter, Holzmann, Bernhard, Morton, Jennifer P., Sansom, Owen J., Caunt, Christopher J., Keyse, Stephen M.

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Interferon-inducible CXC-chemokines are crucial immune modulators and survival predictors in colorectal cancer von Kistner, Larissa, Doll, Dietrich, Holtorf, Anne, Nitsche, Ulrich, Janssen, Klaus-Peter

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The Colorectal Cancer Lipidome: Identification of a Robust Tumor-Specific Lipid Species Signature von Ecker, Josef, Benedetti, Elisa, Kindt, Alida S.D., Höring, Marcus, Perl, Markus, Machmüller, Andrea Christel, Sichler, Anna, Plagge, Johannes, Wang, Yuting, Zeissig, Sebastian, Shevchenko, Andrej, Burkhardt, Ralph, Krumsiek, Jan, Liebisch, Gerhard, Janssen, Klaus-Peter

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Mammalian target of rapamycin (mTOR) orchestrates the defense program of innate immune cells von Schmitz, Frank, Heit, Antje, Dreher, Stefan, Eisenächer, Katharina, Mages, Jörg, Haas, Tobias, Krug, Anne, Janssen, Klaus-Peter, Kirschning, Carsten J, Wagner, Hermann

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Gut microbiota modulate T cell trafficking into human colorectal cancer von Cremonesi, Eleonora, Governa, Valeria, Garzon, Jesus Francisco Glaus, Mele, Valentina, Amicarella, Francesca, Muraro, Manuele Giuseppe, Trella, Emanuele, Galati-Fournier, Virginie, Oertli, Daniel, Däster, Silvio Raffael, Droeser, Raoul A, Weixler, Benjamin, Bolli, Martin, Rosso, Raffaele, Nitsche, Ulrich, Khanna, Nina, Egli, Adrian, Keck, Simone, Slotta-Huspenina, Julia, Terracciano, Luigi M, Zajac, Paul, Spagnoli, Giulio Cesare, Eppenberger-Castori, Serenella, Janssen, Klaus-Peter, Borsig, Lubor, Iezzi, Giandomenica

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Daple is a novel non-receptor GEF required for trimeric G protein activation in Wnt signaling von Aznar, Nicolas, Midde, Krishna K, Dunkel, Ying, Lopez-Sanchez, Inmaculada, Pavlova, Yelena, Marivin, Arthur, Barbazán, Jorge, Murray, Fiona, Nitsche, Ulrich, Janssen, Klaus-Peter, Willert, Karl, Goel, Ajay, Abal, Miguel, Garcia-Marcos, Mikel, Ghosh, Pradipta

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Investigation of Schwann cells at neoplastic cell sites before the onset of cancer invasion von Demir, Ihsan Ekin, Boldis, Alexandra, Pfitzinger, Paulo L, Teller, Steffen, Brunner, Eva, Klose, Natascha, Kehl, Timo, Maak, Matthias, Lesina, Marina, Laschinger, Melanie, Janssen, Klaus-Peter, Algül, Hana, Friess, Helmut, Ceyhan, Güralp O

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MALDI‑2 Mass Spectrometry and Immunohistochemistry Imaging of Gb3Cer, Gb4Cer, and Further Glycosphingolipids in Human Colorectal Cancer Tissue von Bien, Tanja, Perl, Markus, Machmüller, Andrea C, Nitsche, Ulrich, Conrad, Anja, Johannes, Ludger, Müthing, Johannes, Soltwisch, Jens, Janssen, Klaus-Peter, Dreisewerd, Klaus

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Gut microbiota promote liver regeneration through hepatic membrane phospholipid biosynthesis von Yin, Yuhan, Sichler, Anna, Ecker, Josef, Laschinger, Melanie, Liebisch, Gerhard, Höring, Marcus, Basic, Marijana, Bleich, André, Zhang, Xue-Jun, Kübelsbeck, Ludwig, Plagge, Johannes, Scherer, Emely, Wohlleber, Dirk, Wang, Jianye, Wang, Yang, Steffani, Marcella, Stupakov, Pavel, Gärtner, Yasmin, Lohöfer, Fabian, Mogler, Carolin, Friess, Helmut, Hartmann, Daniel, Holzmann, Bernhard, Hüser, Norbert, Janssen, Klaus-Peter

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APC and Oncogenic KRAS Are Synergistic in Enhancing Wnt Signaling in Intestinal Tumor Formation and Progression von Janssen, Klaus–Peter, Alberici, Paola, Fsihi, Hafida, Gaspar, Claudia, Breukel, Cor, Franken, Patrick, Rosty, Christophe, Abal, Miguel, El Marjou, Fatima, Smits, Ron, Louvard, Daniel, Fodde, Riccardo, Robine, Sylvie

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Activated ATF6 Induces Intestinal Dysbiosis and Innate Immune Response to Promote Colorectal Tumorigenesis von Coleman, Olivia I., Lobner, Elena M., Bierwirth, Sandra, Sorbie, Adam, Waldschmitt, Nadine, Rath, Eva, Berger, Emanuel, Lagkouvardos, Ilias, Clavel, Thomas, McCoy, Kathleen D., Weber, Achim, Heikenwalder, Mathias, Janssen, Klaus-Peter, Haller, Dirk

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Cancer cells induce interleukin-22 production from memory CD4⁺ T cells via interleukin-1 to promote tumor growth von Voigt, Cornelia, May, Peter, Gottschlich, Adrian, Markota, Anamarija, Wenk, Daniel, Gerlach, Inga, Voigt, Sebastian, Stathopoulos, Georgios T., Arendt, Kristina A. M., Heise, Constanze, Rataj, Felicitas, Janssen, Klaus-Peter, Königshoff, Melanie, Winter, Hauke, Himsl, Isabelle, Thasler, Wolfgang E., Schnurr, Max, Rothenfußer, Simon, Endres, Stefan, Kobold, Sebastian

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