Nelfinavir Inhibits the TCF11/Nrf1-Mediated Proteasome Recovery Pathway in Multiple Myeloma von Fassmannová, Dominika, Sedlák, František, Sedláček, Jindřich, Špička, Ivan, Grantz Šašková, Klára

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DDI2 protease controls embryonic development and inflammation via TCF11/NRF1 von Nedomova, Monika, Haberecht-Müller, Stefanie, Möller, Sophie, Venz, Simone, Prochazkova, Michaela, Prochazka, Jan, Sedlak, Frantisek, Chawengsaksophak, Kallayanee, Hammer, Elke, Kasparek, Petr, Adamek, Michael, Sedlacek, Radislav, Konvalinka, Jan, Krüger, Elke, Grantz Saskova, Klara

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Lipid Nanoparticles for Broad‐Spectrum Nucleic Acid Delivery von Hejdankova, Zuzana, Vanek, Vaclav, Sedlak, Frantisek, Prochazka, Jan, Diederichs, Audrey, Kereïche, Sami, Novotna, Barbora, Budesinsky, Milos, Birkus, Gabriel, Grantz Saskova, Klara, Cigler, Petr

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The yeast proteases Ddi1 and Wss1 are both involved in the DNA replication stress response von Svoboda, Michal, Konvalinka, Jan, Trempe, Jean-François, Grantz Saskova, Klara

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GS-8374, a Prototype Phosphonate-Containing Inhibitor of HIV-1 Protease, Effectively Inhibits Protease Mutants with Amino Acid Insertions von Grantz Šašková, Klára, Kozíšek, Milan, Stray, Kirsten, de Jong, Dorien, Rezáová, Pavlína, Brynda, Jirí, van Maarseveen, Noortje M, Nijhuis, Monique, Cihlár, Tomáš, Konvalinka, Jan

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Thermodynamic and structural analysis of HIV protease resistance to darunavir – analysis of heavily mutated patient‐derived HIV‐1 proteases von Kožíšek, Milan, Lepšík, Martin, Grantz Šašková, Klára, Brynda, Jiří, Konvalinka, Jan, Řezáčová, Pavlína

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Design of HIV Protease Inhibitors Based on Inorganic Polyhedral Metallacarboranes von Řezáčová, Pavlína, Pokorná, Jana, Brynda, Jiří, Kožíšek, Milan, Cígler, Petr, Lepšík, Martin, Fanfrlík, Jindřich, Řezáč, Jan, Grantz Šašková, Klára, Sieglová, Irena, Plešek, Jaromír, Šícha, Václav, Grüner, Bohumír, Oberwinkler, Heike, Sedláček’, Juraj, Kräusslich, Hans-Georg, Hobza, Pavel, Král, Vladimír, Konvalinka, Jan

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Inorganic Polyhedral Metallacarborane Inhibitors of HIV Protease: A New Approach to Overcoming Antiviral Resistance von Kožíšek, Milan, Cígler, Petr, Lepšík, Martin, Fanfrlík, Jindřich, Řezáčová, Pavlína, Brynda, Jiří, Pokorná, Jana, Plešek, Jaromír, Grüner, Bohumír, Grantz Šašková, Klára, Václavíková, Jana, Král, Vladimír, Konvalinka, Jan

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Specific Inhibitors of HIV Capsid Assembly Binding to the C‑Terminal Domain of the Capsid Protein: Evaluation of 2‑Arylquinazolines as Potential Antiviral Compounds von Machara, Aleš, Lux, Vanda, Kožíšek, Milan, Grantz Šašková, Klára, Štěpánek, Ondřej, Kotora, Martin, Parkan, Kamil, Pávová, Marcela, Glass, Bärbel, Sehr, Peter, Lewis, Joe, Müller, Barbara, Kräusslich, Hans-Georg, Konvalinka, Jan

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Mutations in HIV-1 gag and pol Compensate for the Loss of Viral Fitness Caused by a Highly Mutated Protease von Kozísek, Milan, Henke, Sandra, Sasková, Klára Grantz, Jacobs, Graeme Brendon, Schuch, Anita, Buchholz, Bernd, Müller, Viktor, Kräusslich, Hans-Georg, Rezácová, Pavlína, Konvalinka, Jan, Bodem, Jochen

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Quantitative proteomics reveals neuronal ubiquitination of Rngo/Ddi1 and several proteasomal subunits by Ube3a, accounting for the complexity of Angelman syndrome von Ramirez, Juanma, Lectez, Benoit, Osinalde, Nerea, Sivá, Monika, Elu, Nagore, Aloria, Kerman, Procházková, Michaela, Perez, Coralia, Martínez-Hernández, Jose, Barrio, Rosa, Šašková, Klára Grantz, Arizmendi, Jesus M, Mayor, Ugo

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Structural studies of the yeast DNA damage-inducible protein Ddi1 reveal domain architecture of this eukaryotic protein family von Trempe, Jean-François, Šašková, Klára Grantz, Sivá, Monika, Ratcliffe, Colin D. H., Veverka, Václav, Hoegl, Annabelle, Ménade, Marie, Feng, Xin, Shenker, Solomon, Svoboda, Michal, Kožíšek, Milan, Konvalinka, Jan, Gehring, Kalle

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Human DNA-Damage-Inducible 2 Protein Is Structurally and Functionally Distinct from Its Yeast Ortholog von Sivá, Monika, Svoboda, Michal, Veverka, Václav, Trempe, Jean-François, Hofmann, Kay, Kožíšek, Milan, Hexnerová, Rozálie, Sedlák, František, Belza, Jan, Brynda, Jiří, Šácha, Pavel, Hubálek, Martin, Starková, Jana, Flaisigová, Iva, Konvalinka, Jan, Šašková, Klára Grantz

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Structure-Aided Design of Novel Inhibitors of HIV Protease Based on a Benzodiazepine Scaffold von Schimer, Jiří, Cígler, Petr, Veselý, Jan, Grantz Šašková, Klára, Lepšík, Martin, Brynda, Jiří, Řezáčová, Pavlína, Kožíšek, Milan, Císařová, Ivana, Oberwinkler, Heike, Kraeusslich, Hans-Georg, Konvalinka, Jan

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Molecular Characterization of Clinical Isolates of Human Immunodeficiency Virus Resistant to the Protease Inhibitor Darunavir von SASKOVA, Klara Grantz, KOZISEK, Milan, REZACOVA, Pavlina, BRYNDA, Jirí, YASHINA, Tatyana, KAGAN, Ron M, KONVALINKA, Jan

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Ninety-Nine Is Not Enough: Molecular Characterization of Inhibitor-Resistant Human Immunodeficiency Virus Type 1 Protease Mutants with Insertions in the Flap Region von KOZISEK, Milan, GRANTZ SASKOVA, Klara, REZACOVA, Pavlina, BRYNDA, Jiri, VAN MAARSEVEEN, Noortje M, DE JONG, Dorien, BOUCHER, Charles A, KAGAN, Ron M, NIJHUIS, Monique, KONVALINKA, Jan

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Enzymatic and structural analysis of the I47A mutation contributing to the reduced susceptibility to HIV protease inhibitor lopinavir von Šašková, Klára Grantz, Kožíšek, Milan, Lepšík, Martin, Brynda, Jiří, Řezáčová, Pavlína, Václavíková, Jana, Kagan, Ron M., Machala, Ladislav, Konvalinka, Jan

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Capturing a dynamically interacting inhibitor by paramagnetic NMR spectroscopy von Srb, Pavel, Svoboda, Michal, Benda, Ladislav, Lepšík, Martin, Tarábek, Ján, Šícha, Václav, Grüner, Bohumír, Grantz-Šašková, Klára, Brynda, Jiří, Řezáčová, Pavlína, Konvalinka, Jan, Veverka, Václav

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Potent inhibition of drug-resistant HIV protease variants by monoclonal antibodies von Bartoňová, Vanda, Král, Vlastimil, Sieglová, Irena, Brynda, Jiří, Fábry, Milan, Hořejší, Magdalena, Kožíšek, Milan, Šašková, Klára Grantz, Konvalinka, Jan, Sedláček, Juraj, Řezáčová, Pavlína

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Backbone super(1)H, super(13)C, and super(15)N NMR assignment for the inactive form of the retroviral protease of the murine intracisternal A-type particle, inMIA-14 PR von Motackova, Veronika, Kubickova, Monika, Kozisek, Milan, Saskova, Klara Grantz, Svec, Martin, idek, Lukas, Sklenar, Vladimir

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