Dose-ranging evaluation of intravitreal siRNA PF-04523655 for diabetic macular edema (the DEGAS study) von Nguyen, Quan Dong, Schachar, Ronald A, Nduaka, Chudy I, Sperling, Marvin, Basile, Anthony S, Klamerus, Karen J, Chi-Burris, Katherine, Yan, Eric, Paggiarino, Dario A, Rosenblatt, Irit, Aitchison, Roger, Erlich, Shai S

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Evaluation of the siRNA PF-04523655 versus Ranibizumab for the Treatment of Neovascular Age-related Macular Degeneration (MONET Study) von Nguyen, Quan Dong, MD, MSc, Schachar, Ronald A., MD, PhD, Nduaka, Chudy I., DVM, PhD, Sperling, Marvin, MD, Klamerus, Karen J., PharmD, Chi-Burris, Katherine, MPH, Yan, Eric, PhD, Paggiarino, Dario A., MD, Rosenblatt, Irit, MD, Aitchison, Roger, MS, Erlich, Shai S., PhD

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Pharmacokinetics, metabolism, and excretion of [14C]axitinib, a vascular endothelial growth factor receptor tyrosine kinase inhibitor, in humans von Smith, Bill J, Pithavala, Yazdi, Bu, Hai-Zhi, Kang, Ping, Hee, Brian, Deese, Alan J, Pool, William F, Klamerus, Karen J, Wu, Ellen Y, Dalvie, Deepak K

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Effect of food on the pharmacokinetics of sunitinib malate (SU11248), a multi-targeted receptor tyrosine kinase inhibitor: results from a phase I study in healthy subjects von Bello, Carlo L, Sherman, Laurie, Zhou, Jihao, Verkh, Lev, Smeraglia, John, Mount, Janessa, Klamerus, Karen J

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Pharmacokinetics of Lorlatinib After Single and Multiple Dosing in Patients with Anaplastic Lymphoma Kinase (ALK)-Positive Non-Small Cell Lung Cancer: Results from a Global Phase I... von Chen, Joseph, O’Gorman, Melissa T., James, Lee P., Klamerus, Karen J., Mugundu, Ganesh, Pithavala, Yazdi K.

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Clinical Pharmacology of Axitinib von Chen, Ying, Tortorici, Michael A., Garrett, May, Hee, Brian, Klamerus, Karen J., Pithavala, Yazdi K.

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The effect of tafamidis on the QTc interval in healthy subjects von Klamerus, Karen J., Watsky, Eric, Moller, Robert, Wang, Ronnie, Riley, Steve

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Impact of Acid‐Reducing Agents on the Pharmacokinetics of Palbociclib, a Weak Base With pH‐Dependent Solubility, With Different Food Intake Conditions von Sun, Wan, Klamerus, Karen J., Yuhas, Lisa M., Pawlak, Sylvester, Plotka, Anna, O'Gorman, Melissa, Kirkovsky, Leonid, Kosa, Maha, Wang, Diane

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Tofacitinib (CP-690,550), a Janus Kinase Inhibitor for Dry Eye Disease: Results from a Phase 1/2 Trial von SHIAO HUI, NICHOLS, Kelly K, KLAMERUS, Karen J, LI, JimZ, MIN ZHANG, FOULKS, Gary N

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Tofacitinib (CP-690,550), a Janus Kinase Inhibitor for Dry Eye Disease von Liew, Shiao Hui (Melissa), MBBS, MRCOphth, Nichols, Kelly K., OD, PhD, Klamerus, Karen J., PharmD, Li, Jim Z., PhD, Zhang, Min, MS, Foulks, Gary N., MD, FACS

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Effect of ketoconazole on the pharmacokinetics of axitinib in healthy volunteers von Pithavala, Yazdi K., Tong, Warren, Mount, Janessa, Rahavendran, Sadayappan V., Garrett, May, Hee, Brian, Selaru, Paulina, Sarapa, Nenad, Klamerus, Karen J.

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Evaluation of the effect of food on the pharmacokinetics of axitinib in healthy volunteers von Pithavala, Yazdi K., Chen, Ying, Toh, Melvin, Selaru, Paulina, LaBadie, Robert R., Garrett, May, Hee, Brian, Mount, Janessa, Ni, Grace, Klamerus, Karen J., Tortorici, Michael A.

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Integrating disease progression models, non-clinical pharmacokinetic data and treatment response endpoints to optimize intravitreal dosing regimens von BASILE, Anthony S, JOHNSON, Theodore R, KLAMERUS, Karen J, DUO ZHOU, SULTAN, Marla B, AMANTEA, Mike, NICKENS, Dana J

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Evaluation of the potential interaction between tofacitinib and drugs that undergo renal tubular secretion using metformin, an in vivo marker of renal organic cation transporter 2 von Klamerus, Karen J., Alvey, Christine, Li, Lei, Feng, Bo, Wang, Rong, Kaplan, Irina, Shi, Haihong, Dowty, Martin E., Krishnaswami, Sriram

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Introduction of a Composite Parameter to the Pharmacokinetics of Venlafaxine and its Active O-Desmethyl Metabolite von Klamerus, Karen J., Moloney, Kathleen, Rudolph, Richard L., Sisenwine, Samuel F., Jusko, William J., Chiang, Soong T.

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The effect of tafamidis on the QT c interval in healthy subjects von Klamerus, Karen J., Watsky, Eric, Moller, Robert, Wang, Ronnie, Riley, Steve

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Safety and efficacy of lorlatinib (PF-06463922) from the dose-escalation component of a study in patients with advanced ALK+ or ROS1+ non-small cell lung cancer (NSCLC) von Solomon, Benjamin J., Bauer, Todd Michael, Felip, Enriqueta, Besse, Benjamin, James, Leonard Philip, Clancy, Jill S., Klamerus, Karen J., Martini, Jean-Francois, Abbattista, Antonello, Shaw, Alice Tsang

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A Pharmacokinetic and Pharmacodynamic Study of the Potential Drug Interaction between Tasosartan and Atenolol in Patients with Stage 1 and 2 Essential Hypertension von Andrawis, Nabil S., Battle, Michele M., Klamerus, Karen J., Burghart, Peter H., Neefe, Lynne, Weinryb, Ira, Mayer, Philip, Abernethy, Darrell B.

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Disposition of Intravenous Amiodarone in Subjects with Normal and Impaired Renal Function von Ujhelyi, Michael R., Klamerus, Karen J., Vadiei, Kiumars, O'Rangers, Eleanor, Izard, Mark, Neefe, D. Lynne, Zimmerman, James J., Chow, Moses S. S.

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Pharmacokinetics of Intravenous Amiodarone in Patients with Impaired Left Ventricular Function von Vadiei, Kiumars, O'Rangers, Eleanor A., Klamerus, Karen J., Kluger, Jeffrey, Kazierad, David J., Leese, Philip T., Chow, Moses S., Zimmerman, James J.

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