Wide application of a novel topoisomerase I inhibitor-based drug conjugation technology von Ogitani, Yusuke, Abe, Yuki, Iguchi, Takuma, Yamaguchi, Junko, Terauchi, Tomoko, Kitamura, Michiko, Goto, Koichi, Goto, Mayumi, Oitate, Masataka, Yukinaga, Hideo, Yabe, Yoshiyuki, Nakada, Takashi, Masuda, Takeshi, Morita, Koji, Agatsuma, Toshinori

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Datopotamab Deruxtecan, a Novel TROP2-directed Antibody-drug Conjugate, Demonstrates Potent Antitumor Activity by Efficient Drug Delivery to Tumor Cells von Okajima, Daisuke, Yasuda, Satoru, Maejima, Takanori, Karibe, Tsuyoshi, Sakurai, Ken, Aida, Tetsuo, Toki, Tadashi, Yamaguchi, Junko, Kitamura, Michiko, Kamei, Reiko, Fujitani, Tomomichi, Honda, Tomoyo, Shibutani, Tomoko, Muramatsu, Sumie, Nakada, Takashi, Goto, Riki, Takahashi, Shu, Yamaguchi, Miki, Hamada, Hirofumi, Noguchi, Yutaka, Murakami, Masato, Abe, Yuki, Agatsuma, Toshinori

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Novel anti-EPHA2 antibody, DS-8895a for cancer treatment von Hasegawa, Jun, Sue, Mayumi, Yamato, Michiko, Ichikawa, Junya, Ishida, Saori, Shibutani, Tomoko, Kitamura, Michiko, Wada, Teiji, Agatsuma, Toshinori

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Studies on novel HIF activators, A-503451s: II: biological activities of A-503451A von Kobayashi, Hideki, Ohyama, Takao, Kitamura-Miyazaki, Michiko, Hirota-Takahata, Yuki, Ando, Osamu

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Studies on novel HIF activators, A-503451s: I. Producing organism, fermentation, isolation and structural elucidation von Hirota-Takahata, Yuki, Kobayashi, Hideki, Kizuka, Masaaki, Ohyama, Takao, Kitamura-Miyazaki, Michiko, Suzuki, Yasuhiro, Fujiwara, Mie, Nakajima, Mutsuo, Ando, Osamu

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Identification and Therapeutic Targeting of GPR20, Selectively Expressed in Gastrointestinal Stromal Tumors, with DS-6157a, a First-in-Class Antibody-Drug Conjugate von Iida, Kenji, Abdelhamid Ahmed, Amr H, Nagatsuma, Akiko Kawano, Shibutani, Tomoko, Yasuda, Satoru, Kitamura, Michiko, Hattori, Chiharu, Abe, Manabu, Hasegawa, Jun, Iguchi, Takuma, Karibe, Tsuyoshi, Nakada, Takashi, Inaki, Koichiro, Kamei, Reiko, Abe, Yuki, Nomura, Taisei, Andersen, Jessica L, Santagata, Sandro, Hemming, Matthew L, George, Suzanne, Doi, Toshihiko, Ochiai, Atsushi, Demetri, George D, Agatsuma, Toshinori

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Abstract 2932: Datopotamab deruxtecan (Dato-DXd) enhances antitumor response to PD-1/PD-L1 inhibitors in TROP2-expressing tumors in mice von Okajima, Daisuke, Yasuda, Satoru, Suzuki, Takami, Kitamura, Michiko, Yamaguchi, Junko, Maejima, Takanori, Karibe, Tsuyoshi, Toki, Tadashi, Phillips, Penny, Agatsuma, Toshinori

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Abstract C026: DS-1062a, a novel TROP2-targeting antibody-drug conjugate with a novel DNA topoisomerase I inhibitor DXd, demonstrates potent antitumor activity in preclinical model... von Okajima, Daisuke, Yamaguchi, Junko, Kitamura, Michiko, Kamei, Reiko, Maejima, Takanori, Shibutani, Tomoko, Yasuda, Satoru, Toki, Tadashi, Karibe, Tsuyoshi, Fujitani, Tomomichi, Nakada, Takashi, Goto, Riki, Noguchi, Yutaka, Abe, Yuki, Agatsuma, Toshinori

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Abstract 5181: Therapeutic targeting of GPR20, selectively expressed in gastrointestinal stromal tumor (GIST), with DS-6157a, an antibody-drug conjugate (ADC) von Iida, Kenji, Abdelhamid, Amr H., Nagatsuma, Akiko Kawano, Shibutani, Tomoko, Yasuda, Satoru, Kitamura, Michiko, Hattori, Chiharu, Abe, Manabu, Hasegawa, Jun, Iguchi, Takuma, Karibe, Tsuyoshi, Nakada, Takashi, Inaki, Koichiro, Kamei, Reiko, Abe, Yuki, Andersen, Jessica L., Santagata, Sandro, Hemming, Matthew L., George, Suzanne, Doi, Toshihiko, Ochiai, Atsushi, Demetri, George D., Agatsuma, Toshinori

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Preclinical efficacy studies of DS-1062a, a novel TROP2-targeting antibody-drug conjugate with a novel DNA topoisomerase I inhibitor DXd von Okajima, Daisuke, Yasuda, Satoru, Yokouchi, Yusuke, Fujitani, Tomomichi, Sakurai, Ken, Yamaguchi, Junko, Kitamura, Michiko, Terauchi, Tomoko, Shibutani, Tomoko, Aida, Tetsuo, Nakada, Takashi, Tokuhiro, Shinya, Toki, Tadashi, Noguchi, Yutaka, Abe, Yuki, Agatsuma, Toshinori

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COMBINATION OF ANTIBODY-PYRROLOBENZODIAZEPINE DERIVATIVE CONJUGATE AND PARP INHIBITOR von KITAMURA, Michiko, HARADA, Naoya

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Studies on novel HIF activators, A-503451sII: biological activities of A-503451A von Kobayashi, Hideki, Ohyama, Takao, Kitamura-Miyazaki, Michiko, Hirota-Takahata, Yuki, Ando, Osamu

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COMBINATION OF ANTIBODY-PYRROLOBENZODIAZEPINE DERIVATIVE CONJUGATE AND PARP INHIBITOR von KITAMURA, Michiko, HARADA, Naoya

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Studies on novel HIF activators, A-503451s.I. Producing organism, fermentation, isolation and structural elucidation von Hirota-Takahata, Yuki, Kobayashi, Hideki, Kizuka, Masaaki, Ohyama, Takao, Kitamura-Miyazaki, Michiko, Suzuki, Yasuhiro, Fujiwara, Mie, Nakajima, Mutsuo, Ando, Osamu

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COMBINATION OF ANTIBODY-PYRROLOBENZODIAZEPINE DERIVATIVE CONJUGATE AND PARP INHIBITOR von KITAMURA, Michiko, HARADA, Naoya

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COMBINATION OF ANTIBODY-PYRROLOBENZODIAZEPINE DERIVATIVE CONJUGATE AND PARP INHIBITOR von HARADA, NAOYA, KITAMURA, MICHIKO

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TWI841715B von HARADA, NAOYA, KITAMURA, MICHIKO

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Combinação de conjugado de anticorpo-derivado de pirrolobenzodiazepina e inibidor de parp von KITAMURA MICHIKO, HARADA NAOYA

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COMBINATION OF ANTIBODY-PYRROLOBENZODIAZEPINE DERIVATIVE CONJUGATE AND PARP INHIBITOR von KITAMURA MICHIKO, HARATA NAOYA

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Combination of antibody-pyrrolobenzodiazepine derivative conjugate and parp inhibitor von HARADA, NAOYA, KITAMURA, MICHIKO

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