Key signaling pathways in the muscle‐invasive bladder carcinoma: Clinical markers for disease modeling and optimized treatment von Kiselyov, Alex, Bunimovich‐Mendrazitsky, Svetlana, Startsev, Vladimir

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Design of phosphodiesterase 4D (PDE4D) allosteric modulators for enhancing cognition with improved safety von Burgin, Alex B, Gurney, Mark E, Magnusson, Olafur T, Singh, Jasbir, Witte, Pam, Staker, Bart L, Bjornsson, Jon M, Thorsteinsdottir, Margret, Hrafnsdottir, Sigrun, Hagen, Timothy, Kiselyov, Alex S, Stewart, Lance J

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Synthesis and antiproliferative activity of conformationally restricted 1,2,3-triazole analogues of combretastatins in the sea urchin embryo model and against human cancer cell lin... von Demchuk, Dmitry V., Samet, Alexander V., Chernysheva, Natalia B., Ushkarov, Vladimir I., Stashina, Galina A., Konyushkin, Leonid D., Raihstat, Mikhail M., Firgang, Sergei I., Philchenkov, Alex A., Zavelevich, Michael P., Kuiava, Ludmila M., Chekhun, Vasyl F., Blokhin, Dmitry Yu, Kiselyov, Alex S., Semenova, Marina N., Semenov, Victor V.

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iMyoblasts for ex vivo and in vivo investigations of human myogenesis and disease modeling von Guo, Dongsheng, Daman, Katelyn, Chen, Jennifer Jc, Shi, Meng-Jiao, Yan, Jing, Matijasevic, Zdenka, Rickard, Amanda M, Bennett, Monica H, Kiselyov, Alex, Zhou, Haowen, Bang, Anne G, Wagner, Kathryn R, Maehr, René, King, Oliver D, Hayward, Lawrence J, Emerson, Jr, Charles P

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Sea Urchin Embryo Model As a Reliable in Vivo Phenotypic Screen to Characterize Selective Antimitotic Molecules. Comparative evaluation of Combretapyrazoles, -isoxazoles, -1,2,3-tr... von Semenova, Marina N, Demchuk, Dmitry V, Tsyganov, Dmitry V, Chernysheva, Natalia B, Samet, Alexander V, Silyanova, Eugenia A, Kislyi, Victor P, Maksimenko, Anna S, Varakutin, Alexander E, Konyushkin, Leonid D, Raihstat, Mikhail M, Kiselyov, Alex S, Semenov, Victor V

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Novel Long-Acting Oxytocin Analog with Increased Efficacy in Reducing Food Intake and Body Weight von Elfers, Clinton T, Blevins, James E, Salameh, Therese S, Lawson, Elizabeth A, Silva, David, Kiselyov, Alex, Roth, Christian L

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Polyalkoxybenzenes from Plants. 5. Parsley Seed Extract in Synthesis of Azapodophyllotoxins Featuring Strong Tubulin Destabilizing Activity in the Sea Urchin Embryo and Cell Cultur... von Semenova, Marina N, Kiselyov, Alex S, Tsyganov, Dmitry V, Konyushkin, Leonid D, Firgang, Sergei I, Semenov, Roman V, Malyshev, Oleg R, Raihstat, Mikhail M, Fuchs, Fabian, Stielow, Anne, Lantow, Margareta, Philchenkov, Alex A, Zavelevich, Michael P, Zefirov, Nikolay S, Kuznetsov, Sergei A, Semenov, Victor V

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Discovery of Leukotriene A4 Hydrolase Inhibitors Using Metabolomics Biased Fragment Crystallography von Davies, Douglas R, Mamat, Bjorn, Magnusson, Olafur T, Christensen, Jeff, Haraldsson, Magnus H, Mishra, Rama, Pease, Brian, Hansen, Erik, Singh, Jasbir, Zembower, David, Kim, Hidong, Kiselyov, Alex S, Burgin, Alex B, Gurney, Mark E, Stewart, Lance J

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Robust Reductions of Body Weight and Food Intake by an Oxytocin Analog in Rats von Elfers, Clinton T, Blevins, James E, Lawson, Elizabeth A, Pittner, Richard, Silva, David, Kiselyov, Alex, Roth, Christian L

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Benzimidazolyl-pyrazolo[3,4‑b]pyridinones, Selective Inhibitors of MOLT‑4 Leukemia Cell Growth and Sea Urchin Embryo Spiculogenesis: Target Quest von Lichitsky, Boris V, Komogortsev, Andrey N, Dudinov, Arkady A, Krayushkin, Mikhail M, Khodot, Evgenii N, Samet, Alexander V, Silyanova, Eugenia A, Konyushkin, Leonid D, Karpov, Alexei S, Gorses, Delphine, Radimerski, Thomas, Semenova, Marina N, Kiselyov, Alex S, Semenov, Victor V

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Synthesis of Antimitotic Polyalkoxyphenyl Derivatives of Combretastatin Using Plant Allylpolyalkoxybenzenes von Semenov, Victor V, Kiselyov, Alex S, Titov, Ilia Y, Sagamanova, Irina K, Ikizalp, Natalie N, Chernysheva, Natalia B, Tsyganov, Dmitry V, Konyushkin, Leonid D, Firgang, Sergei I, Semenov, Roman V, Karmanova, Irina B, Raihstat, Mikhail M, Semenova, Marina N

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Structure−Activity Relationship Studies Leading to the Identification of (2E)-3-[l-[(2,4-Dichlorophenyl)methyl]-5-fluoro-3-methyl-lH-indol-7-yl]-N-[(4,5-dichloro-2-thienyl)sulfonyl... von Singh, Jasbir, Zeller, Wayne, Zhou, Nian, Hategan, Georgeta, Mishra, Rama K, Polozov, Alex, Yu, Peng, Onua, Emmanuel, Zhang, Jun, Ramírez, José L, Sigthorsson, Gudmundur, Thorsteinnsdottir, Margret, Kiselyov, Alex. S, Zembower, David E, Andrésson, Thorkell, Gurney, Mark E

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Synthesis and anti-mitotic activity of 6,7-dihydro-4H-isothiazolo[4,5-b]pyridin-5-ones: In vivo and cell-based studies von Semenov, Victor V., Lichitsky, Boris V., Komogortsev, Andrey N., Dudinov, Arkady A., Krayushkin, Mikhail M., Konyushkin, Leonid D., Atamanenko, Olga P., Karmanova, Irina B., Strelenko, Yuri A., Shor, Boris, Semenova, Marina N., Kiselyov, Alex S.

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cis-Restricted 3‑Aminopyrazole Analogues of Combretastatins: Synthesis from Plant Polyalkoxybenzenes and Biological Evaluation in the Cytotoxicity and Phenotypic Sea Urchin Embryo... von Tsyganov, Dmitry V, Konyushkin, Leonid D, Karmanova, Irina B, Firgang, Sergei I, Strelenko, Yuri A, Semenova, Marina N, Kiselyov, Alex S, Semenov, Victor V

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Novel derivatives of 1,3,4-oxadiazoles are potent mitostatic agents featuring strong microtubule depolymerizing activity in the sea urchin embryo and cell culture assays von Kiselyov, Alex S., Semenova, Marina N., Chernyshova, Natalya B., Leitao, Andrei, Samet, Alexandr V., Kislyi, Konstantine A., Raihstat, Mikhail M., Oprea, Tudor, Lemcke, Heiko, Lantow, Margaréta, Weiss, Dieter G., Ikizalp, Nazli N., Kuznetsov, Sergei A., Semenov, Victor V.

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A facile synthesis and microtubule-destabilizing properties of 4-(1H-benzo[d]imidazol-2-yl)-furazan-3-amines von Stepanov, Andrei I., Astrat'ev, Alexander A., Sheremetev, Aleksei B., Lagutina, Nataliya K., Palysaeva, Nadezhda V., Tyurin, Aleksei Yu, Aleksandrova, Nataliya S., Sadchikova, Nataliya P., Suponitsky, Kyrill Yu, Atamanenko, Olga P., Konyushkin, Leonid D., Semenov, Roman V., Firgang, Sergei I., Kiselyov, Alex S., Semenova, Marina N., Semenov, Victor V.

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Efficient Synthesis of Glaziovianin A Isoflavone Series from Dill and Parsley Extracts and Their in Vitro/in Vivo Antimitotic Activity von Semenov, Victor V, Tsyganov, Dmitry V, Semenova, Marina N, Chuprov-Netochin, Roman N, Raihstat, Mikhail M, Konyushkin, Leonid D, Volynchuk, Polina B, Marusich, Elena I, Nazarenko, Vera V, Leonov, Sergey V, Kiselyov, Alex S

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Comparative in vivo evaluation of polyalkoxy substituted 4H-chromenes and oxa-podophyllotoxins as microtubule destabilizing agents in the phenotypic sea urchin embryo assay von Semenova, Marina N., Tsyganov, Dmitry V., Malyshev, Oleg R., Ershov, Oleg V., Bardasov, Ivan N., Semenov, Roman V., Kiselyov, Alex S., Semenov, Victor V.

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Discovery of 4-[(2S)-2-{[4-(4-Chlorophenoxy)phenoxy]methyl}-1-pyrrolidinyl]butanoic Acid (DG-051) as a Novel Leukotriene A4 Hydrolase Inhibitor of Leukotriene B4 Biosynthesis von Sandanayaka, Vincent, Mamat, Bjorn, Mishra, Rama K, Winger, Jennifer, Krohn, Michael, Zhou, Li-Ming, Keyvan, Monica, Enache, Livia, Sullins, David, Onua, Emmanuel, Zhang, Jun, Halldorsdottir, Gudrun, Sigthorsdottir, Heida, Thorlaksdottir, Audur, Sigthorsson, Gudmundur, Thorsteinnsdottir, Margret, Davies, Douglas R, Stewart, Lance J, Zembower, David E, Andresson, Thorkell, Kiselyov, Alex S, Singh, Jasbir, Gurney, Mark E

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Mathematical model for BCG-based treatment of type 1 diabetes von Lazebnik, Teddy, Bunimovich-Mendrazitsky, Svetlana, Kiselyov, Alex

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