Dll4-Notch signaling as a therapeutic target in tumor angiogenesis von Kuhnert, Frank, Kirshner, Jessica R, Thurston, Gavin

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Elesclomol induces cancer cell apoptosis through oxidative stress von Kirshner, Jessica R, He, Suqin, Balasubramanyam, Vishwasenani, Kepros, Jane, Yang, Chin-Yu, Zhang, Mei, Du, Zhenjian, Barsoum, James, Bertin, John

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In-silico discovery of cancer-specific peptide-HLA complexes for targeted therapy von Dhanik, Ankur, Kirshner, Jessica R, MacDonald, Douglas, Thurston, Gavin, Lin, Hsin C, Murphy, Andrew J, Zhang, Wen

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Translational findings for odronextamab: From preclinical research to a first‐in‐human study in patients with CD20+ B‐cell malignancies von Zhu, Min, Olson, Kara, Kirshner, Jessica R., Khaksar Toroghi, Masood, Yan, Hong, Haber, Lauric, Meagher, Craig, Flink, Dina M., Ambati, Srikanth R., Davis, John D., DiCioccio, A. Thomas, Smith, Eric J., Retter, Marc W.

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Bispecific Antibodies and Antibody-Drug Conjugates (ADCs) Bridging HER2 and Prolactin Receptor Improve Efficacy of HER2 ADCs von Andreev, Julian, Thambi, Nithya, Perez Bay, Andres E, Delfino, Frank, Martin, Joel, Kelly, Marcus P, Kirshner, Jessica R, Rafique, Ashique, Kunz, Arthur, Nittoli, Thomas, MacDonald, Douglas, Daly, Christopher, Olson, William, Thurston, Gavin

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A novel, native-format bispecific antibody triggering T-cell killing of B-cells is robustly active in mouse tumor models and cynomolgus monkeys von Smith, Eric J., Olson, Kara, Haber, Lauric J., Varghese, Bindu, Duramad, Paurene, Tustian, Andrew D., Oyejide, Adelekan, Kirshner, Jessica R., Canova, Lauren, Menon, Jayanthi, Principio, Jennifer, MacDonald, Douglas, Kantrowitz, Joel, Papadopoulos, Nicholas, Stahl, Neil, Yancopoulos, George D., Thurston, Gavin, Davis, Samuel

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Identification of TRAIL as an Interferon Regulatory Factor 3 Transcriptional Target von KIRSHNER, Jessica R, KARPOVA, Alla Y, KOPS, Maren, HOWLEY, Peter M

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Dll4 Blockade in Stromal Cells Mediates Antitumor Effects in Preclinical Models of Ovarian Cancer von Kuhnert, Frank, Chen, Guoying, Coetzee, Sandra, Thambi, Nithya, Hickey, Carlos, Shan, Jing, Kovalenko, Pavel, Noguera-Troise, Irene, Smith, Eric, Fairhurst, Jeanette, Andreev, Julian, Kirshner, Jessica R, Papadopoulos, Nicholas, Thurston, Gavin

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Antibody drug conjugates of cleavable amino-benzoyl-maytansinoids von Nittoli, Thomas, Delfino, Frank, Kelly, Marcus, Carosso, Serena, Markotan, Thomas, Kunz, Arthur, Chen, Zhaoyuan, Mao, Shu, Shan, Jing, Navarro, Elizabeth, Zhao, Feng, Makonnen, Sosina, Hickey, Carlos, Spink, Jan, Olson, William, Kirshner, Jessica R., Thurston, Gavin, Papadopoulos, Nicholas

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A PSMA-Targeting CD3 Bispecific Antibody Induces Antitumor Responses that Are Enhanced by 4-1BB Costimulation von Chiu, Danica, Tavare, Richard, Haber, Lauric, Aina, Olulanu H., Vazzana, Kristin, Ram, Priyanka, Danton, Makenzie, Finney, Jennifer, Jalal, Sumreen, Krueger, Pamela, Giurleo, Jason T., Ma, Dangshe, Smith, Eric, Thurston, Gavin, Kirshner, Jessica R., Crawford, Alison

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Antibody drug conjugates of cleavable amino-alkyl and aryl maytansinoids von Nittoli, Thomas, Kelly, Marcus P., Delfino, Frank, Rudge, John, Kunz, Arthur, Markotan, Thomas, Spink, Jan, Chen, Zhaoyuan, Shan, Jing, Navarro, Elizabeth, Tait, Michele, Provoncha, Kathleen, Giurleo, Jason, Zhao, Feng, Jiang, Xiaobo, Hylton, Donna, Makonnen, Sosina, Hickey, Carlos, Kirshner, Jessica R., Thurston, Gavin, Papadopoulos, Nicholas

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A BCMAxCD3 bispecific T cell–engaging antibody demonstrates robust antitumor efficacy similar to that of anti-BCMA CAR T cells von DiLillo, David J., Olson, Kara, Mohrs, Katja, Meagher, Thomas Craig, Bray, Kevin, Sineshchekova, Olga, Startz, Thomas, Kuhnert, Jessica, Retter, Marc W., Godin, Stephen, Sharma, Prachi, Delfino, Frank, Lin, John, Smith, Eric, Thurston, Gavin, Kirshner, Jessica R.

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Preclinical Activity of the Novel Anti-Prolactin Receptor (PRLR) Antibody-Drug Conjugate REGN2878-DM1 in PRLR-Positive Breast Cancers von Kelly, Marcus P, Hickey, Carlos, Makonnen, Sosina, Coetzee, Sandra, Jalal, Sumreen, Wang, Yu, Delfino, Frank, Shan, Jing, Potocky, Terra B, Chatterjee, Ishita, Andreev, Julian, Kunz, Arthur, D'Souza, Christopher, Giurleo, Jason T, Nittoli, Thomas, Trail, Pamela A, Thurston, Gavin, Kirshner, Jessica R

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Preclinical PET imaging with the novel human antibody 89 Zr-DFO-REGN3504 sensitively detects PD-L1 expression in tumors and normal tissues von Kelly, Marcus P, Makonnen, Sosina, Hickey, Carlos, Arnold, T Cody, Giurleo, Jason T, Tavaré, Richard, Danton, Makenzie, Granados, Christian, Chatterjee, Ishita, Dudgeon, Drew, Retter, Marc W, Ma, Dangshe, Olson, William C, Thurston, Gavin, Kirshner, Jessica R

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Transcriptional Activation by the Product of Open Reading Frame 50 of Kaposi’s Sarcoma-Associated Herpesvirus Is Required for Lytic Viral Reactivation in B Cells von Lukac, D M, Kirshner, J R, Ganem, D

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Immuno-PET Monitoring of Lymphocytes Using the CD8-Specific Antibody REGN5054 von Tavaré, Richard, Danton, Makenzie, Giurleo, Jason T, Makonnen, Sosina, Hickey, Carlos, Arnold, Tomas C, Kelly, Marcus P, Fredriksson, Fanny, Bruestle, Karina, Hermann, Aynur, Ullman, Erica, Edelmann, Kurt H, Potocky, Terra, Dudgeon, Drew, Bhatt, Nikunj B, Doubrovin, Mikhail, Barry, Thomas, Kyratsous, Christos A, Gurer, Cagan, Tu, Naxin, Gartner, Hans, Murphy, Andrew, Macdonald, Lynn E, Popke, Jon, Mintz, Akiva, Griesemer, Adam, Olson, William C, Thurston, Gavin, Ma, Dangshe, Kirshner, Jessica R

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Reactivation of Kaposi's Sarcoma-Associated Herpesvirus Infection from Latency by Expression of the ORF 50 Transactivator, a Homolog of the EBV R Protein von Lukac, David M., Renne, Rolf, Kirshner, Jessica R., Ganem, Don

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ImmunoPET Imaging of Endogenous and Transfected Prolactin Receptor Tumor Xenografts von Cheal, Sarah M, Ruan, Shutian, Veach, Darren R, Longo, Valerie A, Punzalan, Blesida J, Wu, Jiong, Fung, Edward K, Kelly, Marcus P, Kirshner, Jessica R, Giurleo, Jason T, Ehrlich, George, Han, Amy Q, Thurston, Gavin, Olson, William C, Zanzonico, Pat B, Larson, Steven M, Carrasquillo, Jorge A

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DNA Binding by Kaposi's Sarcoma-Associated Herpesvirus Lytic Switch Protein Is Necessary for Transcriptional Activation of Two Viral Delayed Early Promoters von Lukac, D M, Garibyan, L, Kirshner, J R, Palmeri, D, Ganem, D

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Ongoing Dll4‐Notch signaling is required for T‐cell homeostasis in the adult thymus von Billiard, Fabienne, Kirshner, Jessica R., Tait, Michelle, Danave, Amanda, Taheri, Sean, Zhang, Wen, Waite, Janelle C., Olson, Kara, Chen, Guoying, Coetzee, Sandra, Hylton, Donna, Murphy, Andrew J., Yancopoulos, George D., Thurston, Gavin, Skokos, Dimitris

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