Discovery of 3‑Pyridyl Isoindolin-1-one Derivatives as Potent, Selective, and Orally Active Aldosterone Synthase (CYP11B2) Inhibitors von Liu, Yongfu, Wu, Jun, Zhou, Mingwei, Chen, Wenming, Li, Dongbo, Wang, Zhanguo, Hornsperger, Benoit, Aebi, Johannes D, Märki, Hans-Peter, Kuhn, Bernd, Wang, Lisha, Kuglstatter, Andreas, Benz, Jörg, Müller, Stephan, Hochstrasser, Remo, Ottaviani, Giorgio, Xin, Jian, Kirchner, Stephan, Mohr, Susanne, Verry, Philippe, Riboulet, William, Shen, Hong C, Mayweg, Alexander V, Amrein, Kurt, Tan, Xuefei

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Computational toxicology in drug development von Muster, Wolfgang, Breidenbach, Alexander, Fischer, Holger, Kirchner, Stephan, Müller, Lutz, Pähler, Axel

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Cardiac Safety of Kinase Inhibitors – Improving Understanding and Prediction of Liabilities in Drug Discovery Using Human Stem Cell-Derived Models von Ziegler, Ricarda, Häusermann, Fabian, Kirchner, Stephan, Polonchuk, Liudmila

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Report from the in vitro micronucleus assay working group von Kirsch-Volders, Micheline, Sofuni, Toshio, Aardema, Marilyn, Albertini, Silvio, Eastmond, David, Fenech, Michael, Ishidate, Motoi, Kirchner, Stephan, Lorge, Elisabeth, Morita, Takeshi, Norppa, Hannu, Surrallés, Jordi, Vanhauwaert, Annelies, Wakata, Akihiro

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Identification of a kinase profile that predicts chromosome damage induced by small molecule kinase inhibitors von Olaharski, Andrew J, Gonzaludo, Nina, Bitter, Hans, Goldstein, David, Kirchner, Stephan, Uppal, Hirdesh, Kolaja, Kyle

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Mouse Lymphoma Thymidine Kinase Gene Mutation Assay: International Workshop on Genotoxicity Tests Workgroup Report—Plymouth, UK 2002 von Moore, Martha M, Honma, Masamitsu, Clements, Julie, Bolcsfoldi, George, Cifone, Maria, Delongchamp, Robert, Fellows, Michael, Gollapudi, Bhaskar, Jenkinson, Peter, Kirby, Paul, Kirchner, Stephan, Muster, Wolfgang, Myhr, Brian, O’Donovan, Michael, Oliver, Jo, Omori, Takashi, Ouldelhkim, Marie-Claude, Pant, Kamala, Preston, Robert, Riach, Colin, San, Richard, Stankowski, Leon F, Thakur, Ajit, Wakuri, Shinobu, Yoshimura, Isao

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Comparison of different cytotoxicity measures for the in vitro micronucleus test (MNVit) in L5178Y tk +/− cells: Summary of 4 compounds (Mitomycin C, Cyclophosphamide, Colchicine a... von Kirchner, Stephan, Zeller, Andreas

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Specific Correction of Alternative Survival Motor Neuron 2 Splicing by Small Molecules: Discovery of a Potential Novel Medicine To Treat Spinal Muscular Atrophy von Ratni, Hasane, Karp, Gary M, Weetall, Marla, Naryshkin, Nikolai A, Paushkin, Sergey V, Chen, Karen S, McCarthy, Kathleen D, Qi, Hongyan, Turpoff, Anthony, Woll, Matthew G, Zhang, Xiaoyan, Zhang, Nanjing, Yang, Tianle, Dakka, Amal, Vazirani, Priya, Zhao, Xin, Pinard, Emmanuel, Green, Luke, David-Pierson, Pascale, Tuerck, Dietrich, Poirier, Agnes, Muster, Wolfgang, Kirchner, Stephan, Mueller, Lutz, Gerlach, Irene, Metzger, Friedrich

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Comparison of different cytotoxicity measures for the in vitro micronucleus test (MNVit) in L5178Y tk^sup +/-^ cells: Summary of 4 compounds (Mitomycin C, Cyclophosphamide, Colchic... von Kirchner, Stephan, Zeller, Andreas

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How to reduce false positive results when undertaking in vitro genotoxicity testing and thus avoid unnecessary follow-up animal tests: Report of an ECVAM Workshop von Kirkland, David, Pfuhler, Stefan, Tweats, David, Aardema, Marilyn, Corvi, Raffaella, Darroudi, Firouz, Elhajouji, Azeddine, Glatt, Hansruedi, Hastwell, Paul, Hayashi, Makoto, Kasper, Peter, Kirchner, Stephan, Lynch, Anthony, Marzin, Daniel, Maurici, Daniela, Meunier, Jean-Roc, Müller, Lutz, Nohynek, Gerhard, Parry, James, Parry, Elizabeth, Thybaud, Veronique, Tice, Ray, van Benthem, Jan, Vanparys, Philippe, White, Paul

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Comparison of different cytotoxicity measures for the in vitro micronucleus test (MNVit) in L5178Y tk+/- cells: Summary of 4 compounds (Mitomycin C, Cyclophosphamide, Colchicine an... von KIRCHNER, Stephan, ZELLER, Andreas

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Using Ovality to Predict Nonmutagenic, Orally Efficacious Pyridazine Amides as Cell Specific Spleen Tyrosine Kinase Inhibitors von Lucas, Matthew C, Bhagirath, Niala, Chiao, Eric, Goldstein, David M, Hermann, Johannes C, Hsu, Pei-Yuan, Kirchner, Stephan, Kennedy-Smith, Joshua J, Kuglstatter, Andreas, Lukacs, Christine, Menke, John, Niu, Linghao, Padilla, Fernando, Peng, Ying, Polonchuk, Liudmila, Railkar, Aruna, Slade, Michelle, Soth, Michael, Xu, Daigen, Yadava, Preeti, Yee, Calvin, Zhou, Mingyan, Liao, Cheng

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Corrigendum to “Report from the in vitro micronucleus assay working group” [Mutat. Res. 540 (2003) 153–163] von Kirsch-Volders, Micheline, Sofuni, Toshio, Aardema, Marilyn, Albertini, Silvio, Eastmond, David, Fenech, Michael, Ishidate, Motoi, Kirchner, Stephan, Lorge, Elisabeth, Morita, Takeshi, Norppa, Hannu, Surrallés, Jordi, Vanhauwaert, Annelies, Wakata, Akihiro

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Evaluation of the GreenScreen GADD45α-GFP indicator assay with non-proprietary and proprietary compounds von Olaharski, Andrew, Albertini, Silvio, Kirchner, Stephan, Platz, Stefan, Uppal, Hirdesh, Lin, Henry, Kolaja, Kyle

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Orally active aminopyridines as inhibitors of tetrameric fructose-1,6-bisphosphatase von Hebeisen, Paul, Haap, Wolfgang, Kuhn, Bernd, Mohr, Peter, Wessel, Hans Peter, Zutter, Ulrich, Kirchner, Stephan, Ruf, Armin, Benz, Jörg, Joseph, Catherine, Alvarez-Sánchez, Rubén, Gubler, Marcel, Schott, Brigitte, Benardeau, Agnes, Tozzo, Effie, Kitas, Eric

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The mechanism of the solute-induced chain interdigitation in phosphatidylcholine vesicles and characterization of the isothermal phase transitions by means of dynamic light scatter... von Nagel, Norbert E., Cevc, Gregor, Kirchner, Stephan

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Identification of a Kinase Profile that Predicts Chromosome Damage Induced by Small Molecule Kinase Inhibitors: e1000446 von Olaharski, Andrew J, Gonzaludo, Nina, Bitter, Hans, Goldstein, David, Kirchner, Stephan, Uppal, Hirdesh, Kolaja, Kyle

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Response to “Genotoxic carcinogen or not genotoxic carcinogen? That is the question. Additional analysis of data from Olaharski et al.” von Olaharski, Andrew, Kolaja, Kyle, Albertini, Silvio, Uppal, Hirdesh, Lin, Henry, Kirchner, Stephan, Platz, Stefan

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Evaluation of the GreenScreen GADD45a-GFP indicator assay with non-proprietary and proprietary compounds von OLAHARSKI, Andrew, ALBERTINI, Silvio, KIRCHNER, Stephan, PLATZ, Stefan, UPPAL, Hirdesh, LIN, Henry, KOLAJA, Kyle

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Suppression of mutagenic activity of a series of 5HT2C receptor agonists by the incorporation of a gem-dimethyl group: SAR using the Ames test and a DNA unwinding assay von Albertini, Silvio, Bös, Michael, Gocke, Elmar, Kirchner, Stephan, Muster, Wolfgang, Wichmann, Jϋrgen

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