Disordered methionine metabolism in MTAP/CDKN2A-deleted cancers leads to dependence on PRMT5 von Mavrakis, Konstantinos J., McDonald, E. Robert, Schlabach, Michael R., Billy, Eric, Hoffman, Gregory R., deWeck, Antoine, Ruddy, David A., Venkatesan, Kavitha, Yu, Jianjun, McAllister, Gregg, Stump, Mark, deBeaumont, Rosalie, Ho, Samuel, Yue, Yingzi, Liu, Yue, Yan-Neale, Yan, Yang, Guizhi, Lin, Fallon, Yin, Hong, Gao, Hui, Kipp, D. Randal, Zhao, Songping, McNamara, Joshua T., Sprague, Elizabeth R., Zheng, Bing, Lin, Ying, Cho, Young Shin, Gu, Justin, Crawford, Kenneth, Ciccone, David, Vitari, Alberto C., Lai, Albert, Capka, Vladimir, Hurov, Kristen, Porter, Jeffery A., Tallarico, John, Mickanin, Craig, Lees, Emma, Pagliarini, Raymond, Keen, Nicholas, Schmelzle, Tobias, Hofmann, Francesco, Stegmeier, Frank, Sellers, William R.

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Geology and Physical Properties Investigations by the InSight Lander von Golombek, M., Grott, M., Kargl, G., Andrade, J., Marshall, J., Warner, N., Teanby, N. A., Ansan, V., Hauber, E., Voigt, J., Lichtenheldt, R., Knapmeyer-Endrun, B., Daubar, I. J., Kipp, D., Muller, N., Lognonné, P., Schmelzbach, C., Banfield, D., Trebi-Ollennu, A., Maki, J., Kedar, S., Mimoun, D., Murdoch, N., Piqueux, S., Delage, P., Pike, W. T., Charalambous, C., Lorenz, R., Fayon, L., Lucas, A., Rodriguez, S., Morgan, P., Spiga, A., Panning, M., Spohn, T., Smrekar, S., Gudkova, T., Garcia, R., Giardini, D., Christensen, U., Nicollier, T., Sollberger, D., Robertsson, J., Ali, K., Kenda, B., Banerdt, W. B.

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Selection of the Mars Science Laboratory Landing Site von Golombek, M., Grant, J., Kipp, D., Vasavada, A., Kirk, R., Fergason, R., Bellutta, P., Calef, F., Larsen, K., Katayama, Y., Huertas, A., Beyer, R., Chen, A., Parker, T., Pollard, B., Lee, S., Sun, Y., Hoover, R., Sladek, H., Grotzinger, J., Welch, R., Noe Dobrea, E., Michalski, J., Watkins, M.

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Selection of the InSight Landing Site von Golombek, M., Kipp, D., Warner, N., Daubar, I. J., Fergason, R., Kirk, R. L., Beyer, R., Huertas, A., Piqueux, S., Putzig, N. E., Campbell, B. A., Morgan, G. A., Charalambous, C., Pike, W. T., Gwinner, K., Calef, F., Kass, D., Mischna, M., Ashley, J., Bloom, C., Wigton, N., Hare, T., Schwartz, C., Gengl, H., Redmond, L., Trautman, M., Sweeney, J., Grima, C., Smith, I. B., Sklyanskiy, E., Lisano, M., Benardini, J., Smrekar, S., Lognonné, P., Banerdt, W. B.

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Identification of GDC-1971 (RLY-1971), a SHP2 Inhibitor Designed for the Treatment of Solid Tumors von Taylor, Alexander M., Williams, Bret R., Giordanetto, Fabrizio, Kelley, Elizabeth H., Lescarbeau, André, Shortsleeves, Kelley, Tang, Yong, Walters, W. Patrick, Arrazate, Alfonso, Bowman, Christine, Brophy, Erin, Chan, Emily W., Deshmukh, Gauri, Greisman, Jack B., Hunsaker, Thomas L., Kipp, D. Randal, Saenz Lopez-Larrocha, Pablo, Maddalo, Danilo, Martin, Iain J., Maragakis, Paul, Merchant, Mark, Murcko, Mark, Nisonoff, Hunter, Nguyen, Vi, Nguyen, Vy, Orozco, Olivia, Owen, Christopher, Pierce, Levi, Schmidt, Molly, Shaw, David E., Smith, Sherri, Therrien, Eric, Tran, John C., Watters, Jim, Waters, Nigel J., Wilbur, Jeremy, Willmore, Lindsay

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Discovery and Clinical Proof-of-Concept of RLY-2608, a First-in-Class Mutant-Selective Allosteric PI3Kα Inhibitor That Decouples Antitumor Activity from Hyperinsulinemia von Varkaris, Andreas, Pazolli, Ermira, Gunaydin, Hakan, Wang, Qi, Pierce, Levi, Boezio, Alessandro A, Bulku, Artemisa, DiPietro, Lucian, Fridrich, Cary, Frost, Adam, Giordanetto, Fabrizio, Hamilton, Erika P, Harris, Katherine, Holliday, Michael, Hunter, Tamieka L, Iskandar, Amanda, Ji, Yongli, Larivée, Alexandre, LaRochelle, Jonathan R, Lescarbeau, André, Llambi, Fabien, Lormil, Brenda, Mader, Mary M, Mar, Brenton G, Martin, Iain, McLean, Thomas H, Michelsen, Klaus, Pechersky, Yakov, Puente-Poushnejad, Erika, Raynor, Kevin, Rogala, Dipali, Samadani, Ramin, Schram, Alison M, Shortsleeves, Kelley, Swaminathan, Sweta, Tajmir, Shahein, Tan, Gege, Tang, Yong, Valverde, Roberto, Wehrenberg, Bryan, Wilbur, Jeremy, Williams, Bret R, Zeng, Hongtao, Zhang, Hanmo, Walters, W Patrick, Wolf, Beni B, Shaw, David E, Bergstrom, Donald A, Watters, James, Fraser, James S, Fortin, Pascal D, Kipp, D Randal

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Mass-Dependent Bond Vibrational Dynamics Influence Catalysis by HIV-1 Protease von Kipp, D. Randal, Silva, Rafael G, Schramm, Vern L

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Suppression of in Vivo β-Amyloid Peptide Toxicity by Overexpression of the HSP-16.2 Small Chaperone Protein von Fonte, Virginia, Kipp, D. Randal, Yerg, John, Merin, David, Forrestal, Margaret, Wagner, Eileen, Roberts, Christine M., Link, Christopher D.

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Analysis of Local Slopes at the InSight Landing Site on Mars von Fergason, R. L., Kirk, R. L., Cushing, G., Galuszka, D. M., Golombek, M. P., Hare, T. M., Howington-Kraus, E., Kipp, D. M., Redding, B. L.

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Transition states of native and drug-resistant HIV-1 protease are the same von Kipp, D. Randal, Hirschi, Jennifer S, Wakata, Aya, Goldstein, Harris, Schramm, Vern L

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Enzyme-Dependent Lysine Deprotonation in EZH2 Catalysis von Kipp, D. Randal, Quinn, Christopher M, Fortin, Pascal D

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Constrained Bonding Environment in the Michaelis Complex of Trypanosoma cruzi Uridine Phosphorylase von Silva, Rafael G, Kipp, D. Randal, Schramm, Vern L

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PET-CT confirmed complete remission and MRD negativity in mantle cell lymphoma patients treated with R-hyper-CVAD results in excellent outcome in the absence of autologous stem cel... von Htet, S., Lane, S., Kipp, D., Rose, H., Campbell, P.

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P720: PROACTIVE DASATINIB DOSE REDUCTION IN THE ALLG CML 12 DIRECT STUDY BASED ON TROUGH LEVELS MINIMISE TOXICITY AND PRESERVE EFFICACY von Yeung, D., Grigg, A., Shanmuganathan, N., Soltenbeck, A., White, D., Branford, S., Viiala, N., Rowlings, P., Mills, A., Shortt, J., Tiley, C., Ross, D., Kipp, D., Harrup, R., Cunningham, I., Kwan, J., Eek, R., Mutsando, H., Tan, K.‐S., Burbury, K., Wright, M., Hughes, T.

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Long-Term Outcomes of Patients with Localized Rectal Cancer Treated with Chemoradiation or Radiotherapy Alone Because of Medical Inoperability or Patient Refusal von Lim, L, Chao, M, Shapiro, J, Millar, J L, Kipp, D, Rezo, A, Fong, A, Jones, I T, McLaughlin, S, Gibbs, P

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Gastroparesis with multiple sclerosis von Raghav, S, Kipp, D, Watson, J, Spring, W

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Mars Science Laboratory entry, descent, and landing system von Steltzner, A., Kipp, D., Chen, A., Burkhart, D., Guernsey, C., Mendeck, G., Mitcheltree, R., Powell, R., Rivellini, T., San Martin, M., Way, D.

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Scurvy results in decreased collagen synthesis and bone density in the guinea pig animal model von KIPP, D. E, MCELVAIN, M, KIMMEL, D. B, AKHTER, M. P, ROBINSON, R. G, LUKERT, B. P

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Acute Pancreatitis with an Ongoing Pancreatic Duct Leak Complicated by Refractory Pleural Effusion: A Case Report von Khiatah, Bashar, Huynh, Thatcher, Frugoli, Amanda, Lyche, Kip D.

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The Novolactone Natural Product Disrupts the Allosteric Regulation of Hsp70 von Hassan, A. Quamrul, Kirby, Christina A., Zhou, Wenlai, Schuhmann, Tim, Kityk, Roman, Kipp, D. Randal, Baird, Jason, Chen, Jinyun, Chen, Yaoyu, Chung, Franklin, Hoepfner, Dominic, Movva, N. Rao, Pagliarini, Raymond, Petersen, Frank, Quinn, Christopher, Quinn, Douglas, Riedl, Ralph, Schmitt, Esther K., Schitter, Anne, Stams, Travis, Studer, Christian, Fortin, Pascal D., Mayer, Matthias P., Sadlish, Heather

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