Rapid single B cell antibody discovery using nanopens and structured light von Winters, Aaron, McFadden, Karyn, Bergen, John, Landas, Julius, Berry, Kelly A, Gonzalez, Anthony, Salimi-Moosavi, Hossein, Murawsky, Christopher M, Tagari, Philip, King, Chadwick T

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Discovery and bio-optimization of human antibody therapeutics using the XenoMouse® transgenic mouse platform von Foltz, Ian N., Gunasekaran, Kannan, King, Chadwick T.

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Molecular Insight into Recognition of the CGRPR Complex by Migraine Prevention Therapy Aimovig (Erenumab) von Garces, Fernando, Mohr, Christopher, Zhang, Li, Huang, Ching-Shin, Chen, Qing, King, Chadwick, Xu, Cen, Wang, Zhulun

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A fully human anti-hepcidin antibody modulates iron metabolism in both mice and nonhuman primates von Cooke, Keegan S., Hinkle, Beth, Salimi-Moosavi, Hossein, Foltz, Ian, King, Chadwick, Rathanaswami, Palaniswami, Winters, Aaron, Steavenson, Shirley, Begley, C. Glenn, Molineux, Graham, Sasu, Barbra J.

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proprotein convertase subtilisin/kexin type 9 neutralizing antibody reduces serum cholesterol in mice and nonhuman primates von Chan, Joyce C.Y, Piper, Derek E, Cao, Qiong, Liu, Dongming, King, Chadwick, Wang, Wei, Tang, Jie, Liu, Qiang, Higbee, Jared, Xia, Zhen, Di, Yongmei, Shetterly, Susan, Arimura, Ziva, Salomonis, Heather, Romanow, William G, Thibault, Stephen T, Zhang, Richard, Cao, Ping, Yang, Xiao-Ping, Yu, Timothy, Lu, Mei, Retter, Marc W, Kwon, Gayle, Henne, Kirk, Pan, Oscar, Tsai, Mei-Mei, Fuchslocher, Bryna, Yang, Evelyn, Zhou, Lei, Lee, Ki Jeong, Daris, Mark, Sheng, Jackie, Wang, Yan, Shen, Wenyan D, Yeh, Wen-Chen, Emery, Maurice, Walker, Nigel P.C, Shan, Bei, Schwarz, Margrit, Jackson, Simon M

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High-throughput screening of hybridoma supernatants using multiplexed fluorescent cell barcoding on live cells von Lu, Mei, Chan, Brian M., Schow, Peter W., Chang, Wesley S., King, Chadwick T.

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The high-resolution crystal structure of human LCAT1 von Piper, Derek E., Romanow, William G., Gunawardane, Ruwanthi N., Fordstrom, Preston, Masterman, Stephanie, Pan, Oscar, Thibault, Stephen T., Zhang, Richard, Meininger, David, Schwarz, Margrit, Wang, Zhulun, King, Chadwick, Zhou, Mingyue, Walker, NigelP.C.

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The high-resolution crystal structure of human LCAT von Piper, Derek E, Romanow, William G, Gunawardane, Ruwanthi N, Fordstrom, Preston, Masterman, Stephanie, Pan, Oscar, Thibault, Stephen T, Zhang, Richard, Meininger, David, Schwarz, Margrit, Wang, Zhulun, King, Chadwick, Zhou, Mingyue, Walker, Nigel P C

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Flow Cytometry-Based Epitope Binning Using Competitive Binding Profiles for the Characterization of Monoclonal Antibodies against Cellular and Soluble Protein Targets von Chan, Brian M., Badh, Anita, Berry, Kelly A., Grauer, Stephanie A., King, Chadwick T.

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Anti-PCSK9 Antibody Pharmacokinetics and Low-Density Lipoprotein-Cholesterol Pharmacodynamics in Nonhuman Primates Are Antigen Affinity–Dependent and Exhibit Limited Sensitivity to... von Henne, Kirk R., Ason, Brandon, Howard, Monique, Wang, Wei, Sun, Jeonghoon, Higbee, Jared, Tang, Jie, Matsuda, Katherine C., Xu, Ren, Zhou, Lei, Chan, Joyce C.Y., King, Chadwick, Piper, Derek E., Ketchem, Randal R., Michaels, Mark Leo, Jackson, Simon M., Retter, Marc W.

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Evaluation of recombinant monoclonal antibody SVmab1 binding to Na V1.7 target sequences and block of human Na V1.7 currents von Liu, Dong, Tseng, Mandy, Epstein, Linda F, Green, Lydia, Chan, Brian, Soriano, Brian, Lim, Desiree, Pan, Oscar, Murawsky, Christopher M, King, Chadwick T, Moyer, Bryan D

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Therapeutic Antibody Targeting Tumor- and Osteoblastic Niche-Derived Jagged1 Sensitizes Bone Metastasis to Chemotherapy von Zheng, Hanqiu, Bae, Yangjin, Kasimir-Bauer, Sabine, Tang, Rebecca, Chen, Jin, Ren, Guangwen, Yuan, Min, Esposito, Mark, Li, Wenyang, Wei, Yong, Shen, Minhong, Zhang, Lanjing, Tupitsyn, Nikolai, Pantel, Klaus, King, Chadwick, Sun, Jan, Moriguchi, Jodi, Jun, Helen Toni, Coxon, Angela, Lee, Brendan, Kang, Yibin

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Discovery and bio-optimization of human antibody therapeutics using the XenoMouse super( registered ) transgenic mouse platform von Foltz, Ian N, Gunasekaran, Kannan, King, Chadwick T

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Antibody‐mediated neutralization of autocrine Gas6 inhibits the growth of pancreatic ductal adenocarcinoma tumors in vivo von Moody, Gordon, Belmontes, Brian, Masterman, Stephanie, Wang, Wei, King, Chadwick, Murawsky, Chris, Tsuruda, Trace, Liu, Shuying, Radinsky, Robert, Beltran, Pedro J.

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Molecular Mechanism of Hepcidin-Mediated Ferroportin Internalization Requires Ferroportin Lysines, Not Tyrosines or JAK-STAT von Ross, Sandra L., Tran, Lynn, Winters, Aaron, Lee, Ki-Jeong, Plewa, Cherylene, Foltz, Ian, King, Chadwick, Miranda, Les P., Allen, Jennifer, Beckman, Holger, Cooke, Keegan S., Moody, Gordon, Sasu, Barbra J., Nemeth, Elizabeta, Ganz, Tomas, Molineux, Graham, Arvedson, Tara L.

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Discovery of the Migraine Prevention Therapeutic Aimovig (Erenumab), the First FDA-Approved Antibody against a G‑Protein-Coupled Receptor von King, Chadwick Terence, Gegg, Colin V, Hu, Sylvia Nai-Yu, Sen Lu, Hsieng, Chan, Brian M, Berry, Kelly A, Brankow, David W, Boone, Tom J, Kezunovic, Nebojsa, Kelley, Matt R, Shi, Licheng, Xu, Cen

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Development and characterization of a human antibody reference panel against erythropoietin suitable for the standardization of ESA immunogenicity testing von Mytych, Daniel T., Barger, Troy E., King, Chadwick, Grauer, Stephanie, Haldankar, Raj, Hsu, Eric, Wu, Michelle Min, Shiwalkar, Mukta, Sanchez, Sergio, Kuck, Andrew, Civoli, Francesca, Sun, Jilin, Swanson, Steven J.

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Abstract 5158: Generation of a fully human Gas6 neutralizing antibody with anti-tumor activity in vivo von Moody, Gordon E., Belmontes, Brian, King, Chadwick, Liu, Shuying, Masterman, Stephanie, Murawsky, Chris, Tsuruda, Trace, Wang, Wei, Radinsky, Robert, Beltran, Pedro J.

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Abstract 558: Targeting tumour heparanase activity using fully human monoclonal antibodies von Rathanaswami, Palaniswami, Pan, Oscar, Ross, Sarah, King, Chadwick, Foltz, Ian N., Elvin, Paul

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Drosophila heterochromatin protein 1 (HP1)/origin recognition complex (ORC) protein is associated with HP1 and ORC and functions in heterochromatin-induced silencing von Shareef, M M, King, C, Damaj, M, Badagu, R, Huang, D W, Kellum, R

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