A robust and adaptive framework for interaction testing in quantitative traits between multiple genetic loci and exposure variables von Hecker, Julian, Prokopenko, Dmitry, Moll, Matthew, Lee, Sanghun, Kim, Wonji, Qiao, Dandi, Voorhies, Kirsten, Kim, Woori, Vansteelandt, Stijn, Hobbs, Brian D, Cho, Michael H, Silverman, Edwin K, Lutz, Sharon M, DeMeo, Dawn L, Weiss, Scott T, Lange, Christoph

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Lack of Association between Oxytocin Receptor (OXTR) Gene Polymorphisms and Alexithymia: Evidence from Patients with Obsessive-Compulsive Disorder von Koh, Min Jung, Kim, Wonji, Kang, Jee In, Namkoong, Kee, Kim, Se Joo

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Family-based exome sequencing combined with linkage analyses identifies rare susceptibility variants of MUC4 for gastric cancer von Choi, Yoon Jin, Ohn, Jung Hun, Kim, Nayoung, Kim, Wonji, Park, Kyungtaek, Won, Sungho, Sael, Lee, Shin, Cheol Min, Lee, Sun Min, Lee, Sejoon, An, Hyun Joo, Jang, Dong Man, Han, Byung Woo, Lee, Hye Seung, Kang, Seung Joo, Kim, Joo Sung, Lee, Dong Ho

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Effect of 6p21 region on lung function is modified by smoking: a genome-wide interaction study von Park, Boram, An, Jaehoon, Kim, Wonji, Kang, Hae Yeon, Koh, Sang Baek, Oh, Bermseok, Jung, Keum Ji, Jee, Sun Ha, Kim, Woo Jin, Cho, Michael H., Silverman, Edwin K., Park, Taesung, Won, Sungho

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Machine learning models for predicting blood pressure phenotypes by combining multiple polygenic risk scores von Hrytsenko, Yana, Shea, Benjamin, Elgart, Michael, Kurniansyah, Nuzulul, Lyons, Genevieve, Morrison, Alanna C., Carson, April P., Haring, Bernhard, Mitchell, Braxton D., Psaty, Bruce M., Jaeger, Byron C., Gu, C. Charles, Kooperberg, Charles, Levy, Daniel, Lloyd-Jones, Donald, Choi, Eunhee, Brody, Jennifer A., Smith, Jennifer A., Rotter, Jerome I., Moll, Matthew, Fornage, Myriam, Simon, Noah, Castaldi, Peter, Casanova, Ramon, Chung, Ren-Hua, Kaplan, Robert, Loos, Ruth J. F., Kardia, Sharon L. R., Rich, Stephen S., Redline, Susan, Kelly, Tanika, O’Connor, Timothy, Zhao, Wei, Kim, Wonji, Guo, Xiuqing, Ida Chen, Yii-Der, Sofer, Tamar

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Evidence for shared genetic risk factors between lymphangioleiomyomatosis and pulmonary function von Farré, Xavier, Espín, Roderic, Baiges, Alexandra, Blommaert, Eline, Kim, Wonji, Giannikou, Krinio, Herranz, Carmen, Román, Antonio, Sáez, Berta, Casanova, Álvaro, Ancochea, Julio, Valenzuela, Claudia, Ussetti, Piedad, Laporta, Rosalía, Rodríguez-Portal, José A, van Moorsel, Coline H M, van der Vis, Joanne J, Quanjel, Marian J R, Tena-Garitaonaindia, Mireia, Sánchez de Medina, Fermín, Mateo, Francesca, Molina-Molina, María, Won, Sungho, Kwiatkowski, David J, de Cid, Rafael, Pujana, Miquel Angel

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Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program von Taliun, Daniel, Kessler, Michael D., Carlson, Jedidiah, Taliun, Sarah A. Gagliano, Kang, Hyun Min, Pitsillides, Achilleas N., Emde, Anne-Katrin, Clarke, Wayne E., Shetty, Amol C., Wong, Quenna, Bobo, Dean M., Aguet, François, Albert, Christine, Aslibekyan, Stella, Barnard, John, Barr, R. Graham, Barwick, Lucas, Becker, Lewis C., Bielak, Lawrence F., Blangero, John, Bowden, Donald W., Burchard, Esteban G., Chalazan, Brandon, Chasman, Daniel I., Chen, Yii-Der Ida, Choi, Seung Hoan, Chung, Mina K., Curran, Joanne E., Daya, Michelle, Ellinor, Patrick T., Fatkin, Diane, Fingerlin, Tasha, Forer, Lukas, Franceschini, Nora, Germer, Soren, Gladwin, Mark T., Hall, Michael E., He, Jiang, Johnsen, Jill M., Johnson, Andrew D., Kardia, Sharon L. R., Klemmer, Robert, Kooperberg, Charles, Köttgen, Anna, Lange, Leslie A., Lin, Xihong, Lin, Keng-Han, Liu, Chunyu, Loos, Ruth J. F., Gerszten, Robert, Lunetta, Kathryn L., Mak, Angel C. Y., Manichaikul, Ani, Manning, Alisa K., Mathias, Rasika A., McManus, David D., McGarvey, Stephen T., Meigs, James B., Minear, Mollie A., Mitchell, Braxton D., Mohanty, Sanghamitra, Montasser, May E., Montgomery, Courtney, Morrison, Alanna C., Murabito, Joanne M., Natale, Andrea, Nelson, Sarah C., Palmer, Nicholette D., Pankratz, Nathan, Peyser, Patricia A., Post, Wendy S., Psaty, Bruce M., Rao, D. C., Reiner, Alexander P., Roden, Dan, Rotter, Jerome I., Schoenherr, Sebastian, Seo, Jeong-Sun, Sheu, Wayne H., Smith, Nicholas L., Smith, Jennifer A., Stilp, Adrienne M., Telen, Marilyn, Thornton, Timothy A., Tracy, Russell P., Van Den Berg, David J., Vasan, Ramachandran S., Vrieze, Scott, Weng, Lu-Chen, Zhao, Xutong, Boerwinkle, Eric, Gibbs, Richard, Rich, Stephen S., Silverman, Edwin K., Qasba, Pankaj, Gan, Weiniu, Zöllner, Sebastian, Wilson, James G., Laurie, Cathy C., Jaquish, Cashell E.

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Heritability estimation of dichotomous phenotypes using a liability threshold model on ascertained family‐based samples von Kim, Wonji, Kwak, Soo Heon, Won, Sungho

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CFTR variants are associated with chronic bronchitis in smokers von Saferali, Aabida, Qiao, Dandi, Kim, Wonji, Raraigh, Karen, Levy, Hara, Diaz, Alejandro A., Cutting, Garry R., Cho, Michael H., Hersh, Craig P.

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Prenatal exposure to persistent organic pollutants and methylation of LINE-1 and imprinted genes in placenta: A CHECK cohort study von Kim, Sujin, Cho, Yoon Hee, Lee, Inae, Kim, Wonji, Won, Sungho, Ku, Ja-Lok, Moon, Hyo-Bang, Park, Jeongim, Kim, Sungkyoon, Choi, Gyuyeon, Choi, Kyungho

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Colocalization analysis of 3' UTR alternative polyadenylation quantitative trait loci reveals novel mechanisms underlying associations with lung function von Saferali, Aabida, Kim, Wonji, Xu, Zhonghui, Chase, Robert P, Cho, Michael H, Laederach, Alain, Castaldi, Peter J, Hersh, Craig P

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Improving Disease Prediction by Incorporating Family Disease History in Risk Prediction Models with Large-Scale Genetic Data von Gim, Jungsoo, Kim, Wonji, Kwak, Soo Heon, Choi, Hosik, Park, Changyi, Park, Kyong Soo, Kwon, Sunghoon, Park, Taesung, Won, Sungho

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C FTR variants are associated with chronic bronchitis in smokers von Saferali, Aabida, Qiao, Dandi, Kim, Wonji, Raraigh, Karen, Levy, Hara, Diaz, Alejandro A, Cutting, Garry R, Cho, Michael H, Hersh, Craig P

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Longitudinal Association Between Muscle Loss and Mortality in Ever Smokers von Make, Barry, Dransfield, Mark T., Young, Kendra, Kinney, Greg, San Jose Estepar, Raul, Cummings, Sara, Make, Barry J., Nabbosa, Juliet, Port, Emily, Stepp, Lori, Beaty, Terri, Curtis, Jeffrey L., Hokanson, John E., Lynch, David A., Anderson, Gary, Gan, Weiniu, Viviano, Lisa M., Tal-Singer, Ruth, Baraghoshi, David, Knowles, Ruthie, Czizik, Annika, Lutz, Sharon M., Young, Kendra A., Cho, Michael, Castaldi, Peter J., Kim, Wonji, Ghosh, Auyon, Hobbs, Brian, Kim, Woori, McGeachie, Michael, Moll, Matthew, Qiao, Dandi, Fain, Sean B., Hoffman, Eric A., Humphries, Stephen, Judy, Philip F., Stefanie Mason, Alex Kluiber, Poynton, Clare, Steiner, Robert M., van Beek, Edwin, Ginneken, Bram van, van Rikxoort, Eva, Washko, George R., John E. Hokanson, Co-Chair, Watts, Shandi, Han, MeiLan, Regan, Elizabeth, Anzueto, Antonio, Bailey, William C., Criner, Gerard J., Kinney, Greg, Sprenger, Kim, Lambert, Allison, Oates, Gabriela, Jacobson, Francine, McCormack, Meredith C., van Beek, Edwin JR, Zhang, Jingzhou, Li, Yisha, Lowe, Katherine E., Wilson, Ava, Baldomero, Adrienne, O’Brien, James, Wise, Robert A., Eakin, Michelle, Henkle, Ben, Iyer, Anand, McEvoy, Charlene, Yohannes, Abebaw, Hobbs, Brian D., Monaco, Thomas, Jacobson, Francine L., Maguire, Cherie, Barr, R. Graham, Almonte, Casandra, Gomez Blum, Maria Lorena, McAdams, H. Page, Brown, Robert, Budoff, Matt, Calmelat, Robert, Indelicato, Renee Love, Soriano, April, Baldomero, Arianne, Bell, Brian, Deconcini, Miranda, Loes, Linda, Flenaugh, Eric L., Abson, Kema, Gebrekristos, Hirut, Johnson, Priscilla, Finigan, Jay, Andries, Nicole, D’Alonzo, Gilbert, Marchetti, Nathaniel, Satti, Aditi, McClain, Anny, Gil, Marissa, Martineau, Amber, Reston, Tara, Laroia, Archana

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Causes of and Clinical Features Associated with Death in Tobacco Cigarette Users by Lung Function Impairment von Labaki, Wassim W, Gu, Tian, Murray, Susan, Curtis, Jeffrey L, Wells, J Michael, Bhatt, Surya P, Bon, Jessica, Diaz, Alejandro A, Hersh, Craig P, Wan, Emily S, Kim, Victor, Beaty, Terri H, Hokanson, John E, Bowler, Russell P, Arenberg, Douglas A, Kazerooni, Ella A, Martinez, Fernando J, Silverman, Edwin K, Crapo, James D, Make, Barry J, Regan, Elizabeth A, Han, MeiLan K

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Alpha-1 Antitrypsin MZ Heterozygosity Is an Endotype of Chronic Obstructive Pulmonary Disease von Ghosh, Auyon J, Hobbs, Brian D, Moll, Matthew, Saferali, Aabida, Boueiz, Adel, Yun, Jeong H, Sciurba, Frank, Barwick, Lucas, Limper, Andrew H, Flaherty, Kevin, Criner, Gerard, Brown, Kevin K, Wise, Robert, Martinez, Fernando J, Lomas, David, Castaldi, Peter J, Carey, Vincent J, DeMeo, Dawn L, Cho, Michael H, Silverman, Edwin K, Hersh, Craig P

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Pulmonary Arterial Pruning and Longitudinal Change in Percent Emphysema and Lung Function: The Genetic Epidemiology of COPD Study von Pistenmaa, Carrie L, Nardelli, P, Ash, S Y, Come, C E, Diaz, A A, Rahaghi, F N, Barr, R G, Young, K A, Kinney, G L, Simmons, J P, Wade, R C, Wells, J M, Hokanson, J E, Washko, G R, San José Estépar, R

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Single-trait and multi-trait genome-wide association analyses identify novel loci for blood pressure in African-ancestry populations von Liang, Jingjing, Le, Thu H, Edwards, Digna R Velez, Tayo, Bamidele O, Gaulton, Kyle J, Smith, Jennifer A, Lu, Yingchang, Jensen, Richard A, Chen, Guanjie, Yanek, Lisa R, Schwander, Karen, Tajuddin, Salman M, Sofer, Tamar, Kim, Wonji, Kayima, James, McKenzie, Colin A, Fox, Ervin, Nalls, Michael A, Young, J Hunter, Sun, Yan V, Lane, Jacqueline M, Cechova, Sylvia, Zhou, Jie, Tang, Hua, Fornage, Myriam, Musani, Solomon K, Wang, Heming, Lee, Juyoung, Adeyemo, Adebowale, Dreisbach, Albert W, Forrester, Terrence, Chu, Pei-Lun, Cappola, Anne, Evans, Michele K, Morrison, Alanna C, Martin, Lisa W, Wiggins, Kerri L, Hui, Qin, Zhao, Wei, Jackson, Rebecca D, Ware, Erin B, Faul, Jessica D, Reiner, Alex P, Bray, Michael, Denny, Joshua C, Mosley, Thomas H, Palmas, Walter, Guo, Xiuqing, Papanicolaou, George J, Penman, Alan D, Polak, Joseph F, Rice, Kenneth, Taylor, Ken D, Boerwinkle, Eric, Bottinger, Erwin P, Liu, Kiang, Risch, Neil, Hunt, Steven C, Kooperberg, Charles, Zonderman, Alan B, Laurie, Cathy C, Becker, Diane M, Cai, Jianwen, Loos, Ruth J F, Psaty, Bruce M, Weir, David R, Kardia, Sharon L R, Arnett, Donna K, Won, Sungho, Edwards, Todd L, Redline, Susan, Cooper, Richard S, Rao, D C, Rotter, Jerome I, Rotimi, Charles, Levy, Daniel, Chakravarti, Aravinda, Zhu, Xiaofeng, Franceschini, Nora

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A genome-wide association study implicates NR2F2 in lymphangioleiomyomatosis pathogenesis von Kim, Wonji, Giannikou, Krinio, Dreier, John R, Lee, Sanghun, Tyburczy, Magdalena E, Silverman, Edwin K, Radzikowska, Elżbieta, Wu, Shulin, Wu, Chin-Lee, Henske, Elizabeth P, Hunninghake, Gary, Carel, Havi, Roman, Antonio, Pujana, Miquel Angel, Moss, Joel, Won, Sungho, Kwiatkowski, David J

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Whole genome sequence analysis of pulmonary function and COPD in 19,996 multi-ethnic participants von Zhao, Xutong, Qiao, Dandi, Yang, Chaojie, Kasela, Silva, Kim, Wonji, Ma, Yanlin, Shrine, Nick, Batini, Chiara, Sofer, Tamar, Taliun, Sarah A. Gagliano, Sakornsakolpat, Phuwanat, Balte, Pallavi P., Prokopenko, Dmitry, Yu, Bing, Lange, Leslie A., Dupuis, Josée, Cade, Brian E., Lee, Jiwon, Gharib, Sina A., Daya, Michelle, Laurie, Cecelia A., Ruczinski, Ingo, Cupples, L. Adrienne, Loehr, Laura R., Bartz, Traci M., Morrison, Alanna C., Psaty, Bruce M., Vasan, Ramachandran S., Wilson, James G., Taylor, Kent D., Durda, Peter, Johnson, W. Craig, Cornell, Elaine, Guo, Xiuqing, Liu, Yongmei, Tracy, Russell P., Ardlie, Kristin G., Aguet, François, VanDenBerg, David J., Papanicolaou, George J., Rotter, Jerome I., Barnes, Kathleen C., Jain, Deepti, Nickerson, Deborah A., Muzny, Donna M., Metcalf, Ginger A., Doddapaneni, Harshavardhan, Dugan-Perez, Shannon, Gupta, Namrata, Gabriel, Stacey, Rich, Stephen S., O’Connor, George T., Redline, Susan, Reed, Robert M., Laurie, Cathy C., Daviglus, Martha L., Preudhomme, Liana K., Burkart, Kristin M., Kaplan, Robert C., Wain, Louise V., Tobin, Martin D., London, Stephanie J., Lappalainen, Tuuli, Oelsner, Elizabeth C., Abecasis, Goncalo R., Silverman, Edwin K., Barr, R. Graham, Cho, Michael H., Manichaikul, Ani

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