Hyperdynamic microtubules, cognitive deficits, and pathology are improved in tau transgenic mice with low doses of the microtubule-stabilizing agent BMS-241027 von Barten, Donna M, Fanara, Patrizia, Andorfer, Cathy, Hoque, Nina, Wong, P Y Anne, Husted, Kristofor H, Cadelina, Gregory W, Decarr, Lynn B, Yang, Ling, Liu, Victoria, Fessler, Chancy, Protassio, Joan, Riff, Timothy, Turner, Holly, Janus, Christopher G, Sankaranarayanan, Sethu, Polson, Craig, Meredith, Jere E, Gray, Gemma, Hanna, Amanda, Olson, Richard E, Kim, Soong-Hoon, Vite, Gregory D, Lee, Francis Y, Albright, Charles F

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Discovery of a Hydroxypyridinone APJ Receptor Agonist as a Clinical Candidate von Johnson, James A, Kim, Soong-Hoon, Jiang, Ji, Phillips, Monique, Schumacher, William A, Bostwick, Jeffrey S, Gargalovic, Peter S, Onorato, Joelle M, Luk, Chiuwa E, Generaux, Claudia, He, Yan, Chen, Xue-Qing, Xu, Carrie, Galella, Michael A, Wang, Tao, Gordon, David A, Wexler, Ruth R, Finlay, Heather J

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Structure-based design of potent and selective inhibitors of collagenase-3 (MMP-13) von Kim, Soong-Hoon, Pudzianowski, Andrew T., Leavitt, Kenneth J., Barbosa, Joseph, McDonnell, Patricia A., Metzler, William J., Rankin, Bruce M., Liu, Richard, Vaccaro, Wayne, Pitts, William

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Catalytic Ring-Closing Metathesis of Dienes: Application to the Synthesis of Eight-Membered Rings von Miller, Scott J, Kim, Soong-Hoon, Chen, Zhong-Ren, Grubbs, Robert H

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Identification of Reversible Small Molecule Inhibitors of Endothelial Lipase (EL) That Demonstrate HDL‑C Increase In Vivo von Tora, George, Kim, Soong-Hoon, Pi, Zulan, Johnson, James A, Jiang, Ji, Phillips, Monique, Lloyd, John, Abell, Lynn M, Lu, Hao, Locke, Gregory, Adam, Leonard P, Taylor, David S, Yin, Xiaohong, Behnia, Kamelia, Zhao, Lei, Yang, Richard, Basso, Michael, Caporuscio, Christian, Chen, Alice Ye, Liu, Eddie, Kirshgessner, Todd, Onorato, Joelle M, Ryan, Carol, Traeger, Sarah C, Gordon, David, Wexler, Ruth R, Finlay, Heather J

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Identification of substituted benzothiazole sulfones as potent and selective inhibitors of endothelial lipase von Kim, Soong-Hoon, Johnson, James A., Jiang, Ji, Parkhurst, Brandon, Phillips, Monique, Pi, Zulan, Qiao, Jennifer X., Tora, George, Ye Chen, Alice, Liu, Eddie, Yin, Xiaohong, Yang, Richard, Zhao, Lei, Taylor, David S., Basso, Michael, Behnia, Kamelia, Onorato, Joelle, Chen, Xue-Qing, Abell, Lynn M., Lu, Hao, Locke, Gregory, Caporuscio, Christian, Adam, Leonard P., Gordon, David, Wexler, Ruth R., Finlay, Heather J.

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Catalytic Ring Closing Metathesis of Dienynes: Construction of Fused Bicyclic Rings von Kim, Soong-Hoon, Bowden, Ned, Grubbs, Robert H

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New dual inhibitors of EGFR and HER2 protein tyrosine kinases von Fink, Brian E., Vite, Gregory D., Mastalerz, Harold, Kadow, John F., Kim, Soong-Hoon, Leavitt, Kenneth J., Du, Karen, Crews, Donald, Mitt, Toomas, Wong, Tai W., Hunt, John T., Vyas, Dolatrai M., Tokarski, John S.

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Corrigendum to “Identification of substituted benzothiazole sulfones as potent and selective inhibitors of endothelial lipase” [Bioorg. Med. Chem. Lett. 29 (2019) 1918–1921] von Kim, Soong-Hoon, Johnson, James A., Jiang, Ji, Parkhurst, Brandon, Phillips, Monique, Pi, Zulan, Qiao, Jennifer X., Tora, George, Ye Chen, Alice, Liu, Eddie, Yin, Xiaohong, Yang, Richard, Zhao, Lei, Taylor, David S., Basso, Michael, Behnia, Kamelia, Onorato, Joelle, Chen, Xue-Qing, Abell, Lynn M., Lu, Hao, Locke, Gregory, Caporuscio, Christian, Adam, Leonard P., Gordon, David, Wexler, Ruth R., Finlay, Heather J.

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Catalytic Ring Closing Metathesis of Dienynes:  Construction of Fused Bicyclic [ n . m.0] Rings von Kim, Soong-Hoon, Zuercher, William J, Bowden, Ned B, Grubbs, Robert H

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Synthesis, Structure Proof, and Biological Activity of Epothilone Cyclopropanes von Johnson, James, Kim, Soong-Hoon, Bifano, Marc, DiMarco, John, Fairchild, Craig, Gougoutas, Jack, Lee, Francis, Long, Byron, Tokarski, John, Vite, Gregory

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Novel pyrrolo[2,1- f][1,2,4]triazin-4-amines: Dual inhibitors of EGFR and HER2 protein tyrosine kinases von Fink, Brian E., Norris, Derek, Mastalerz, Harold, Chen, Ping, Goyal, Bindu, Zhao, Yufen, Kim, Soong-Hoon, Vite, Gregory D., Lee, Francis Y., Zhang, Hongjian, Oppenheimer, Simone, Tokarski, John S., Wong, Tai W., Gavai, Ashvinikumar V.

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Regioselective synthesis of folate receptor-targeted agents derived from epothilone analogs and folic acid von Vlahov, Iontcho R., Vite, Gregory D., Kleindl, Paul J., Wang, Yu, Santhapuram, Hari Krishna R., You, Fei, Howard, Stephen J., Kim, Soong-Hoon, Lee, Francis F.Y., Leamon, Christopher P.

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Discovery and Preclinical Evaluation of [4-[[1-(3-fluorophenyl)methyl]-1H-indazol-5-ylamino]-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl]carbamic Acid, (3S)-3-Morpholinylmethyl Ester... von Gavai, Ashvinikumar V, Fink, Brian E, Fairfax, David J, Martin, Gregory S, Rossiter, Lana M, Holst, Christian L, Kim, Soong-Hoon, Leavitt, Kenneth J, Mastalerz, Harold, Han, Wen-Ching, Norris, Derek, Goyal, Bindu, Swaminathan, Shankar, Patel, Bharat, Mathur, Arvind, Vyas, Dolatrai M, Tokarski, John S, Yu, Chiang, Oppenheimer, Simone, Zhang, Hongjian, Marathe, Punit, Fargnoli, Joseph, Lee, Francis Y, Wong, Tai W, Vite, Gregory D

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Discovery of low nanomolar non-hydroxamate inhibitors of tumor necrosis factor-α converting enzyme (TACE) von Duan, James J.-W., Chen, Lihua, Lu, Zhonghui, Jiang, Bin, Asakawa, Naoyuki, Sheppeck, James E., Liu, Rui-Qin, Covington, Maryanne B., Pitts, William, Kim, Soong-Hoon, Decicco, Carl P.

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Design, synthesis, functional and structural characterization of an inhibitor of N-acetylneuraminate-9-phosphate phosphatase: Observation of extensive dynamics in an enzyme/inhibit... von Kim, Soong-Hoon, Constantine, Keith L., Duke, Gerald J., Goldfarb, Valentina, Hunt, John T., Johnson, Stephen, Kish, Kevin, Klei, Herbert E., McDonnell, Patricia A., Metzler, William J., Mueller, Luciano, Poss, Michael A., Fairchild, Craig R., Bhide, Rajeev S.

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Discovery of (R)-7-Cyano-2,3,4,5-tetrahydro-1-(1H-imidazol-4-ylmethyl)-3- (phenylmethyl)-4-(2-thienylsulfonyl)-1H-1,4-benzodiazepine (BMS-214662), a Farnesyltransferase Inhibitor w... von Hunt, John T, Ding, Charles Z, Batorsky, Roberta, Bednarz, Mark, Bhide, Rajeev, Cho, Young, Chong, Saeho, Chao, Sam, Gullo-Brown, Johnni, Guo, Peng, Kim, Soong Hoon, Lee, Francis Y. F, Leftheris, Katerina, Miller, Arthur, Mitt, Toomas, Patel, Manorama, Penhallow, Becky A, Ricca, Carol, Rose, William C, Schmidt, Robert, Slusarchyk, William A, Vite, Gregory, Manne, Veeraswamy

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Identification of 2-amino-5-(thioaryl)thiazoles as inhibitors of nerve growth factor receptor TrkA von Kim, Soong-Hoon, Tokarski, John S., Leavitt, Kenneth J., Fink, Brian E., Salvati, Mark E., Moquin, Robert, Obermeier, Mary T., Trainor, George L., Vite, Gregory G., Stadnick, Linda K., Lippy, Jonathan S., You, Dan, Lorenzi, Matthew V., Chen, Ping

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Synthesis, Chromatographic Purification, and Isolation of Epothilone–Folic Acid Conjugate BMS-753493 von Kim, Soong-Hoon, de Mas, Nuria, Parlanti, Luca, Lyngberg, Olav K, Ströhlein, Guido, Guo, Zhenrong, Dambalas, Konstantinos, Rosso, Victor W, Yang, Bing-Shiou, Girard, Kevin P, Manaloto, Zerene A, D’Arasmo, Germano, Frigerio, Riccardo E, Wang, Wei, Lu, Xujin, Bolgar, Mark S, Gokhale, Madhushree, Thakur, Ajit B

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Synthesis and Biological Activity of Novel Epothilone Aziridines von Regueiro-Ren, Alicia, Borzilleri, Robert M, Zheng, Xiaoping, Kim, Soong-Hoon, Johnson, James A, Fairchild, Craig R, Lee, Francis Y. F, Long, Byron H, Vite, Gregory D

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