Myelodysplastic Syndrome associated TET2 mutations affect NK cell function and genome methylation von Boy, Maxime, Bisio, Valeria, Zhao, Lin-Pierre, Guidez, Fabien, Schell, Bérénice, Lereclus, Emilie, Henry, Guylaine, Villemonteix, Juliette, Rodrigues-Lima, Fernando, Gagne, Katia, Retiere, Christelle, Larcher, Lise, Kim, Rathana, Clappier, Emmanuelle, Sebert, Marie, Mekinian, Arsène, Fain, Olivier, Caignard, Anne, Espeli, Marion, Balabanian, Karl, Toubert, Antoine, Fenaux, Pierre, Ades, Lionel, Dulphy, Nicolas

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Distinct pattern of genomic breakpoints in CML and BCR::ABL1-positive ALL: analysis of 971 patients von Hovorkova, Lenka, Winkowska, Lucie, Skorepova, Justina, Krumbholz, Manuela, Benesova, Adela, Polivkova, Vaclava, Alten, Julia, Bardini, Michela, Meyer, Claus, Kim, Rathana, Trahair, Toby N, Clappier, Emmanuelle, Chiaretti, Sabina, Henderson, Michelle, Sutton, Rosemary, Sramkova, Lucie, Stary, Jan, Polakova, Katerina Machova, Marschalek, Rolf, Metzler, Markus, Cazzaniga, Giovanni, Cario, Gunnar, Trka, Jan, Zaliova, Marketa, Zuna, Jan

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Differential activation of basal and IL-7-induced PI3K/Akt/ mTOR and JAK/STAT5 signaling distinguishes pediatric from adult acute lymphoblastic leukemia von Fernandes, Marta B, Gomes, A Margarida, Oliveira, Mariana L, Caldas, Joana, Lúcio, Paulo, Kim, Rathana, Caye-Eude, Aurélie, Pereira, Filomena, De Sousa, Aida B, De Stefano, Alessia, Follo, Matilde Y, Soares, Maria V, Lacerda, João F, Desterro, Joana, Cavé, Hélène, Clappier, Emmanuelle, Duarte, Ximo, Ribeiro, Patrícia, Barata, João T

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Ikaros deficiency is associated with aggressive BCR-ABL1 B-cell precursor acute lymphoblastic leukemia independent of the lineage and developmental origin von Simand, Célestine, Keime, Céline, Cayé, Aurélie, Arfeuille, Chloé, Passet, Marie, Kim, Rathana, Cavé, Hélène, Clappier, Emmanuelle, Kastner, Philippe, Chan, Susan, Heizmann, Beate

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Allogeneic transplantation in acute myelogenous leukemia: a comprehensive single institution's experience von Socie, Gerard, Galimard, Jacques-Emmanuel, Raffoux, Emmanuel, Itzykson, Raphael, Debureaux, Pierre Edouard, Michonneau, David, Lengliné, Etienne, Robin, Marie, De Fontbrune, Flore Sicre, Sébert, Marie, Xhaard, Aliénor, Kim, Rathana, Couprie, Anne, Dhedin, Nathalie, Dragani, Matteo, Lemaire, Pierre, Larcher, Lise, Clappier, Emmanuelle, Boissel, Nicolas, Soulier, Jean, Dombret, Hervé, Fenaux, Pierre, De Latour, Régis Peffault, Adès, Lionel

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Lymphopenia confers poorer prognosis in Myelodysplastic Syndromes with very low and low IPSS-M von Fandrei, David, Huynh, Tony, Sébert, Marie, Aguinaga, Lorea, Bisio, Valeria, Kim, Rathana, Clappier, Emmanuelle, Espéli, Marion, Balabanian, Karl, Moins-Teisserenc, Hélène, Toubert, Antoine, Dulphy, Nicolas, Fenaux, Pierre, Adès, Lionel, Zhao, Lin-Pierre

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Hematopoietic differentiation at single-cell resolution in NPM1-mutated AML von Duchmann, Matthieu, Joudinaud, Romane, Boudry, Augustin, Pasanisi, Justine, Di Feo, Giuseppe, Kim, Rathana, Bucci, Maxime, Chauvel, Clémentine, Chat, Laureen, Larcher, Lise, Pacchiardi, Kim, Mathis, Stéphanie, Raffoux, Emmanuel, Adès, Lionel, Berthon, Céline, Clappier, Emmanuelle, Roumier, Christophe, Puissant, Alexandre, Preudhomme, Claude, Duployez, Nicolas, Itzykson, Raphaël

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A multiparametric niche-like drug screening platform in acute myeloid leukemia von Dal Bello, Reinaldo, Pasanisi, Justine, Joudinaud, Romane, Duchmann, Matthieu, Pardieu, Bryann, Ayaka, Paolo, Di Feo, Giuseppe, Sodaro, Gaetano, Chauvel, Clémentine, Kim, Rathana, Vasseur, Loic, Chat, Laureen, Ling, Frank, Pacchiardi, Kim, Vaganay, Camille, Berrou, Jeannig, Benaksas, Chaima, Boissel, Nicolas, Braun, Thorsten, Preudhomme, Claude, Dombret, Hervé, Raffoux, Emmanuel, Fenouille, Nina, Clappier, Emmanuelle, Adès, Lionel, Puissant, Alexandre, Itzykson, Raphael

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P319: IL7‐RECEPTOR EXPRESSION IS FREQUENT IN T‐CELL ACUTE LYMPHOBLASTIC LEUKEMIA AND PREDICTS SENSITIVITY TO JAK‐INHIBITION von Courtois, Lucien, Cabannes‐Hamy, Aurélie, Kim, Rathana, Delecourt, Marine, Pinton, Antoine, Charbonnier, Guillaume, Feroul, Melanie, Smith, Charlotte, Tueur, Giulia, Pivert, Cecile, Balducci, Estelle, Simonin, Mathieu, Spicuglia, Salvatore, Boissel, Nicolas, Andrieu, Guillaume, Asnafi, Vahid, Rousselot, Philippe, Lhermitte, Ludovic

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A "foamy" mastocytosis case von Kim, Rathana, Lhermitte, Ludovic

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P315: TP53 ALTERATIONS AND MRD REFINE PROGNOSIS OF ADULT KMT2A‐REARRANGED B‐ALL von Kim, Rathana, Bergugnat, Hugo, Pasquier, Florence, Raffoux, Emmanuel, Larcher, Lise, Passet, Marie, Pastoret, Cedric, Nathalie, Grardel, Asnafi, Vahid, Delabesse, Eric, Caye‐Eude, Aurélie, Meyer, Claus, Masrschalek, Rolf, Thiebaut‐Bertrand, Anne, Balsat, Marie, Escoffre, Martine, Blum, Sabine, Baumann, Michael, Banos, Anne, Straetmans, Nicole, Pilar Gallego Hernanz, Maria, Chalandon, Yves, Graux, Carlos, Leguay, Thibaut, Hunault, Mathilde, Huguet, Françoise, Lhéritier, Véronique, Soulier, Jean, Boissel, Nicolas, Clappier, Emmanuelle

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Prognostic impact of DDX41 germline mutations in intensively treated acute myeloid leukemia patients: an ALFA-FILO study von Duployez, Nicolas, Largeaud, Laëtitia, Duchmann, Matthieu, Kim, Rathana, Rieunier, Julie, Lambert, Juliette, Bidet, Audrey, Larcher, Lise, Lemoine, Jean, Delhommeau, François, Hirsch, Pierre, Fenwarth, Laurène, Kosmider, Olivier, Decroocq, Justine, Bouvier, Anne, Le Bris, Yannick, Ochmann, Marlène, Santagostino, Alberto, Adès, Lionel, Fenaux, Pierre, Thomas, Xavier, Micol, Jean-Baptiste, Gardin, Claude, Itzykson, Raphael, Soulier, Jean, Clappier, Emmanuelle, Recher, Christian, Preudhomme, Claude, Pigneux, Arnaud, Dombret, Hervé, Delabesse, Eric, Sébert, Marie

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UBA1 Variations in Neutrophilic Dermatosis Skin Lesions of Patients With VEXAS Syndrome von Zakine, Eve, Schell, Bérénice, Battistella, Maxime, Vignon-Pennamen, Marie-Dominique, Chasset, François, Mahévas, Thibault, Cordoliani, Florence, Adès, Lionel, Sébert, Marie, Delaleu, Jérémie, Jachiet, Marie, Lepelletier, Clémence, Lemaire, Pierre, Chauvel, Clémentine, Dhouaieb, Bedis, Kim, Rathana, Cassius, Charles, Georgin-Lavialle, Sophie, Mekinian, Arsène, Bagot, Martine, Braun, Thorsten, Rousset, Laurie, Begon, Edouard, de Masson, Adèle, Fenaux, Pierre, Clappier, Emmanuelle, Bouaziz, Jean-David

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Clinical, pathological, and molecular features of myelodysplasia cutis von Delaleu, Jérémie, Kim, Rathana, Zhao, Lin-Pierre, de Masson, Adèle, Vignon-Pennamen, Marie-Dominique, Cassius, Charles, Ram-Wolff, Caroline, Bagot, Martine, Clappier, Emmanuelle, Adès, Lionel, Sebert, Marie, Bouaziz, Jean-David, Fenaux, Pierre, Battistella, Maxime

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IL-7 receptor expression is frequent in T-cell acute lymphoblastic leukemia and predicts sensitivity to JAK inhibition von Courtois, Lucien, Cabannes-Hamy, Aurélie, Kim, Rathana, Delecourt, Marine, Pinton, Antoine, Charbonnier, Guillaume, Feroul, Mélanie, Smith, Charlotte, Tueur, Giulia, Pivert, Cécile, Balducci, Estelle, Simonin, Mathieu, Angel, Laure Hélène, Spicuglia, Salvatore, Boissel, Nicolas, Andrieu, Guillaume P., Asnafi, Vahid, Rousselot, Philippe, Lhermitte, Ludovic

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IL7-receptor expression is frequent in T-cell acute lymphoblastic leukemia and predicts sensitivity to JAK-inhibition von Courtois, Lucien, Cabannes-Hamy, Aurelie, Kim, Rathana, Delecourt, Marine, Pinton, Antoine, Charbonnier, Guillaume, Féroul, Mélanie, Smith, Charlotte, Tueur, Giulia, Pivert, Cecile, Balducci, Estelle, Simonin, Mathieu, Angel, Laure Hélène, Spicuglia, Salvatore, Boissel, Nicolas, Andrieu, Guillaume P, Asnafi, Vahid, Rousselot, Philippe, Lhermitte, Ludovic

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Fractionated Inotuzumab Ozogamicin Combined with Low-Intensity Chemotherapy in Older Patients with Newly Diagnosed CD22+ Philadelphia Chromosome (Ph)-Negative B-Cell Precursor (BCP... von Chevallier, Patrice, Leguay, Thibault, KIM, Rathana, Delord, Marc, Doubek, Michael, Huguet, Francoise, Cabannes-Hamy, Aurelie, Wartiovaara-Kautto, Ulla, Saillard, Colombe, Raffoux, Emmanuel, Cluzeau, Thomas, Lepretre, Stephane, Balsat, Marie, Berceanu, Anna, Boissel, Nicolas, Gardin, Claude, Clappier, Emmanuelle, Dombret, Herve, Rousselot, Philippe

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Prevalence of UBA1 mutations in MDS/CMML patients with systemic inflammatory and auto-immune disease von Zhao, Lin-Pierre, Schell, Berenice, Sébert, Marie, Kim, Rathana, Lemaire, Pierre, Boy, Maxime, Mathis, Stephanie, Larcher, Lise, Chauvel, Clémentine, Dhouaieb, Mohamed Bedis, Bisio, Valéria, Preudhomme, Claude, Marceau-Renaut, Alice, Itzykson, Raphaël, Mekinian, Arsène, Fain, Olivier, Toubert, Antoine, Fenaux, Pierre, Dulphy, Nicolas, Clappier, Emmanuelle, Adès, Lionel

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Minimal residual disease quantification in ovarian tissue collected from patients in complete remission of acute leukemia von Chevillon, Florian, Clappier, Emmanuelle, Arfeuille, Chloé, Cayuela, Jean-Michel, Dalle, Jean Hugues, Kim, Rathana, Caye-Eude, Aurélie, Chalas, Céline, Abdo, Chrystelle, Drouineaud, Véronique, Peffault de Latour, Régis, Alcantara, Marion, Uzunov, Madalina, Degaud, Michael, Meignin, Véronique, Dombret, Hervé, Boissel, Nicolas, Poirot, Catherine, Dhédin, Nathalie

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Genetic alterations and MRD refine risk assessment for KMT2A-rearranged B-cell precursor ALL in adults: a GRAALL study von Kim, Rathana, Bergugnat, Hugo, Pastoret, Cédric, Pasquier, Florence, Raffoux, Emmanuel, Larcher, Lise, Passet, Marie, Grardel, Nathalie, Delabesse, Eric, Kubetzko, Susanne, Caye-Eude, Aurélie, Meyer, Claus, Marschalek, Rolf, Lafage-Pochitaloff, Marine, Thiebaut-Bertrand, Anne, Balsat, Marie, Escoffre-Barbe, Martine, Blum, Sabine, Baumann, Michael, Banos, Anne, Straetmans, Nicole, Gallego-Hernanz, Maria-Pilar, Chalandon, Yves, Graux, Carlos, Soulier, Jean, Leguay, Thibaut, Hunault, Mathilde, Huguet, Françoise, Lhéritier, Véronique, Dombret, Hervé, Boissel, Nicolas, Clappier, Emmanuelle

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