DCZ0415, a small‐molecule inhibitor targeting TRIP13, inhibits EMT and metastasis via inactivation of the FGFR4/STAT3 axis and the Wnt/β‐catenin pathway in colorectal cancer von Agarwal, Sumit, Afaq, Farrukh, Bajpai, Prachi, Kim, Hyung‐Gyoon, Elkholy, Amr, Behring, Michael, Chandrashekar, Darshan Shimoga, Diffalha, Sameer Al, Khushman, Moh’d, Sugandha, Shajan P., Varambally, Sooryanarayana, Manne, Upender

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TRIP13 promotes metastasis of colorectal cancer regardless of p53 and microsatellite instability status von Agarwal, Sumit, Behring, Michael, Kim, Hyung‐Gyoon, Chandrashekar, Darshan S., Chakravarthi, Balabhadrapatruni V. S. K., Gupta, Nirzari, Bajpai, Prachi, Elkholy, Amr, Al Diffalha, Sameer, Datta, Pran K., Heslin, Martin J., Varambally, Sooryanarayana, Manne, Upender

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Targeting of oncogenic AAA-ATPase TRIP13 reduces progression of pancreatic ductal adenocarcinoma von Afaq, Farrukh, Agarwal, Sumit, Bajpai, Prachi, Diffalha, Sameer Al, Kim, Hyung-Gyoon, Peter, Shajan, Khushman, Moh'd, Chauhan, Subhash C, Mukherjee, Priyabrata, Varambally, Sooryanarayana, Manne, Upender

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Targeting P4HA1 with a Small Molecule Inhibitor in a Colorectal Cancer PDX Model von Agarwal, Sumit, Behring, Michael, Kim, Hyung-Gyoon, Bajpai, Prachi, Chakravarthi, Balabhadrapatruni V.S.K., Gupta, Nirzari, Elkholy, Amr, Al Diffalha, Sameer, Varambally, Sooryanarayana, Manne, Upender

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Developing 3D Organoid Raft Cultures from Patient-Derived Xenografts as Rapid Models to Screen Efficacy of Experimental Therapeutics von Bajpai, Prachi, Banerjee, Nilam Sanjib, Moore, Dianne W, Kim, Hyung-Gyoon, Afaq, Farrukh, Contreras, Carlo M, Heslin, Martin J, Reddy, Vishnu B, Peter, Shajan, Varambally, Sooryanarayana, Al Diffalha, Sameer, Manne, Upender

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PAICS, a Purine Nucleotide Metabolic Enzyme, is Involved in Tumor Growth and the Metastasis of Colorectal Cancer von Agarwal, Sumit, Chakravarthi, Balabhadrapatruni V S K, Behring, Michael, Kim, Hyung-Gyoon, Chandrashekar, Darshan S, Gupta, Nirzari, Bajpai, Prachi, Elkholy, Amr, Balasubramanya, Sai A H, Hardy, Cherlene, Diffalha, Sameer Al, Varambally, Sooryanarayana, Manne, Upender

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Immunophenotype‐associated gene signature in ductal breast tumors varies by receptor subtype, but the expression of individual signature genes remains consistent von Behring, Michael, Ye, Yuanfan, Elkholy, Amr, Bajpai, Prachi, Agarwal, Sumit, Kim, Hyung‐Gyoon, Ojesina, Akinyemi I., Wiener, Howard W, Manne, Upender, Shrestha, Sadeep, Vazquez, Ana I.

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Comparative analysis of triple-negative breast cancer transcriptomics of Kenyan, African American and Caucasian Women von Saleh, Mansoor, Chandrashekar, Darshan Shimoga, Shahin, Sayed, Agarwal, Sumit, Kim, Hyung-Gyoon, Behring, Michael, Shaikh, Asim Jamal, Moloo, Zahir, Eltoum, Isam-Eldin A, Yates, Clayton, Varambally, Sooryanarayana, Manne, Upender

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PAICS, a De Novo Purine Biosynthetic Enzyme, Is Overexpressed in Pancreatic Cancer and Is Involved in Its Progression von Agarwal, Sumit, Chakravarthi, Balabhadrapatruni V.S.K., Kim, Hyung-Gyoon, Gupta, Nirzari, Hale, Kevin, Balasubramanya, Sai Akshaya Hodigere, Oliver, Patsy G., Thomas, Dafydd G., Eltoum, Isam-Eldin A., Buchsbaum, Donald J., Manne, Upender, Varambally, Sooryanarayana

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Ebf1-mediated down-regulation of Id2 and Id3 is essential for specification of the B cell lineage von Thal, Melissa A, Carvalho, Thiago L, He, Ti, Kim, Hyung-Gyoon, Gao, Hua, Hagman, James, Klug, Christopher A

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Molecular disparities in colorectal cancers of White Americans, Alabama African Americans, and Oklahoma American Indians von Yamada, Hiroshi Y., Xu, Chao, Jones, Kenneth L., O’Neill, Philip H., Venkateshwar, Madka, Chiliveru, Srikanth, Kim, Hyung-Gyoon, Doescher, Mark, Morris, Katherine T., Manne, Upender, Rao, Chinthalapally V.

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Microbiome diversity in African American, European American, and Egyptian colorectal cancer patients von Elkholy, Amr, Avuthu, Nagavardhini, Abdalla, Mohammed, Behring, Michael, Bajpai, Prachi, Kim, Hyung-Gyoon, Header, Doaa, Abo Elwafa, Reham AH, Saed, Hesham, Embaby, Amira, El-Nikhely, Nefertiti, Obuya, Sarah, Mohamed, Mostafa, Badawy, Ahmed Ashour, Nawar, Ahmed, Afaq, Farrukh, Rogers, Laura Q., Bae, Sejong, Shikany, James M., Bateman, Lori Brand, Fouad, Mona, Saleh, Mansoor, Samuel, Temesgen, Varambally, Sooryanarayana, Guda, Chittibabu, Arafat, Waleed, Manne, Upender

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BZW2 Inhibition Reduces Colorectal Cancer Growth and Metastasis von Agarwal, Sumit, Afaq, Farrukh, Bajpai, Prachi, Behring, Michael, Kim, Hyung-Gyoon, Varambally, Amith, Chandrashekar, Darshan S, Peter, Shajan, Diffalha, Sameer Al, Khushman, Moh'd, Seeber, Andreas, Varambally, Sooryanarayana, Manne, Upender

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Combination of dual JAK/HDAC inhibitor with regorafenib synergistically reduces tumor growth, metastasis, and regorafenib-induced toxicity in colorectal cancer von Bajpai, Prachi, Agarwal, Sumit, Afaq, Farrukh, Al Diffalha, Sameer, Chandrashekar, Darshan S, Kim, Hyung-Gyoon, Shelton, Abigail, Miller, C Ryan, Singh, Santosh K, Singh, Rajesh, Varambally, Sooryanarayana, Nagaraju, Ganji Purnachandra, Manne, Ashish, Paluri, Ravi, Khushman, Moh'd, Manne, Upender

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The ETS family transcription factor PU.1 is necessary for the maintenance of fetal liver hematopoietic stem cells von Kim, Hyung-Gyoon, de Guzman, Cristina G., Swindle, C. Scott, Cotta, Claudiu V., Gartland, Larry, Scott, Edward W., Klug, Christopher A.

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Identification of Distinct Heterogenic Subtypes and Molecular Signatures Associated with African Ancestry in Triple Negative Breast Cancer Using Quantified Genetic Ancestry Models... von Davis, Melissa, Martini, Rachel, Newman, Lisa, Elemento, Olivier, White, Jason, Verma, Akanksha, Datta, Indrani, Adrianto, Indra, Chen, Yalei, Gardner, Kevin, Kim, Hyung-Gyoon, Colomb, Windy D, Eltoum, Isam-Eldin, Frost, Andra R, Grizzle, William E, Sboner, Andrea, Manne, Upender, Yates, Clayton

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Inactivation of Smad4 accelerates Kras(G12D)-mediated pancreatic neoplasia von Kojima, Kyoko, Vickers, Selwyn M, Adsay, N Volkan, Jhala, Nirag C, Kim, Hyung-Gyoon, Schoeb, Trenton R, Grizzle, William E, Klug, Christopher A

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A signature of Prevotella copri and Faecalibacterium prausnitzii depletion, and a link with bacterial glutamate degradation in the Kenyan colorectal cancer patients von Obuya, Sarah, Elkholy, Amr, Avuthu, Nagavardhini, Behring, Michael, Bajpai, Prachi, Agarwal, Sumit, Kim, Hyung-Gyoon, El-Nikhely, Nefertiti, Akinyi, Pamela, Orwa, James, Afaq, Farrukh, Abdalla, Mohammed, Michael, Anwar, Farouk, Mohamed, Bateman, Lori Brand, Fouad, Mona, Saleh, Mansoor, Guda, Chittibabu, Manne, Upender, Arafat, Waleed

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Absence of inhibition of cutaneous wound healing in mice by oral doxycycline von Hebda, Patricia A., Whaley, Diana, Kim, Hyung-Gyoon, Wells, Alan

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Distinct classes of c-Kit–activating mutations differ in their ability to promote RUNX1-ETO–associated acute myeloid leukemia von Nick, Heidi J., Kim, Hyung-Gyoon, Chang, Chia-Wei, Harris, Kevin W., Reddy, Vishnu, Klug, Christopher A.

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