Mechanisms for copper acquisition, distribution and regulation von Kim, Byung-Eun, Nevitt, Tracy, Thiele, Dennis J

Volltext

Elesclomol alleviates Menkes pathology and mortality by escorting Cu to cuproenzymes in mice von Guthrie, Liam M, Soma, Shivatheja, Yuan, Sai, Silva, Andres, Zulkifli, Mohammad, Snavely, Thomas C, Greene, Hannah Faith, Nunez, Elyssa, Lynch, Brogan, De Ville, Courtney, Shanbhag, Vinit, Lopez, Franklin R, Acharya, Arjun, Petris, Michael J, Kim, Byung-Eun, Gohil, Vishal M, Sacchettini, James C

Volltext

A Novel Role for Copper in Ras/Mitogen-Activated Protein Kinase Signaling von Turski, Michelle L., Brady, Donita C., Kim, Hyung J., Kim, Byung-Eun, Nose, Yasuhiro, Counter, Christopher M., Winge, Dennis R., Thiele, Dennis J.

Volltext

Organ-specific regulation of ATP7A abundance is coordinated with systemic copper homeostasis von Chun, Haarin, Catterton, Tracy, Kim, Heejeong, Lee, Jaekwon, Kim, Byung-Eun

Volltext

A new Caenorhabditis elegans model to study copper toxicity in Wilson disease von Catalano, Federico, O'Brien, Thomas J., Mekhova, Aleksandra A., Sepe, Lucia Vittoria, Elia, Mariantonietta, De Cegli, Rossella, Gallotta, Ivan, Santonicola, Pamela, Zampi, Giuseppina, Ilyechova, Ekaterina Y., Romanov, Aleksei A., Samuseva, Polina D., Salzano, Josephine, Petruzzelli, Raffaella, Polishchuk, Elena V., Indrieri, Alessia, Kim, Byung‐Eun, Brown, André E. X., Puchkova, Ludmila V., Di Schiavi, Elia, Polishchuk, Roman S.

Volltext

Ctr2 regulates biogenesis of a cleaved form of mammalian Ctr1 metal transporter lacking the copper- and cisplatin-binding ecto-domain von Öhrvik, Helena, Nose, Yasuhiro, Wood, L Kent, Kim, Byung-Eun, Gleber, Sophie-Charlotte, Ralle, Martina, Thiele, Dennis J

Volltext

Ctr1 drives intestinal copper absorption and is essential for growth, iron metabolism, and neonatal cardiac function von Nose, Yasuhiro, Kim, Byung-Eun, Thiele, Dennis J.

Volltext

An extracellular histidine-containing motif in the zinc transporter ZIP4 plays a role in zinc sensing and zinc-induced endocytosis in mammalian cells von Chun, Haarin, Korolnek, Tamara, Lee, Chul-Jin, Coyne, H. Jerome, Winge, Dennis R., Kim, Byung-Eun, Petris, Michael J.

Volltext

Mitochondrial dysfunction reactivates α-fetoprotein expression that drives copper-dependent immunosuppression in mitochondrial disease models von Jett, Kimberly A, Baker, Zakery N, Hossain, Amzad, Boulet, Aren, Cobine, Paul A, Ghosh, Sagnika, Ng, Philip, Yilmaz, Orhan, Barreto, Kris, DeCoteau, John, Mochoruk, Karen, Ioannou, George N, Savard, Christopher, Yuan, Sai, Abdalla, Osama Hmh, Lowden, Christopher, Kim, Byung-Eun, Cheng, Hai-Ying Mary, Battersby, Brendan J, Gohil, Vishal M, Leary, Scot C

Volltext

A Histidine-rich Cluster Mediates the Ubiquitination and Degradation of the Human Zinc Transporter, hZIP4, and Protects against Zinc Cytotoxicity von Mao, Xiaoqing, Kim, Byung-Eun, Wang, Fudi, Eide, David J., Petris, Michael J.

Volltext

The Function of ATPase Copper Transporter ATP7B in Intestine von Pierson, Hannah, Muchenditsi, Abigael, Kim, Byung-Eun, Ralle, Martina, Zachos, Nicholas, Huster, Dominik, Lutsenko, Svetlana

Volltext

The Mammalian Zip5 Protein Is a Zinc Transporter That Localizes to the Basolateral Surface of Polarized Cells von Wang, Fudi, Kim, Byung-Eun, Petris, Michael J., Eide, David J.

Volltext

Acrodermatitis enteropathica mutations affect transport activity, localization and zinc-responsive trafficking of the mouse ZIP4 zinc transporter von Wang, Fudi, Kim, Byung-Eun, Dufner-Beattie, Jodi, Petris, Michael J., Andrews, Glen, Eide, David J.

Volltext

Zinc-stimulated Endocytosis Controls Activity of the Mouse ZIP1 and ZIP3 Zinc Uptake Transporters von Fudi Wang, Jodi Dufner-Beattie, Byung-Eun Kim, Michael J. Petris, Glen Andrews, David J. Eide

Volltext

Phenotypic diversity of Menkes disease in mottled mice is associated with defects in localisation and trafficking of the ATP7A protein von Kim, Byung-Eun, Petris, Michael J

Volltext

CHCA-1 is a copper-regulated CTR1 homolog required for normal development, copper accumulation, and copper-sensing behavior in Caenorhabditis elegans von Yuan, Sai, Sharma, Anuj Kumar, Richart, Alexandria, Lee, Jaekwon, Kim, Byung-Eun

Volltext

Elesclomol restores mitochondrial function in genetic models of copper deficiency von Soma, Shivatheja, Latimer, Andrew J., Chun, Haarin, Vicary, Alison C., Timbalia, Shrishiv A., Boulet, Aren, Rahn, Jennifer J., Chan, Sherine S. L., Leary, Scot C., Kim, Byung-Eun, Gitlin, Jonathan D., Gohil, Vishal M.

Volltext

The Intestinal Copper Exporter CUA-1 Is Required for Systemic Copper Homeostasis in Caenorhabditis elegans von Chun, Haarin, Sharma, Anuj Kumar, Lee, Jaekwon, Chan, Jefferson, Jia, Shang, Kim, Byung-Eun

Volltext

Cardiac Copper Deficiency Activates a Systemic Signaling Mechanism that Communicates with the Copper Acquisition and Storage Organs von Kim, Byung-Eun, Turski, Michelle L., Nose, Yasuhiro, Casad, Michelle, Rockman, Howard A., Thiele, Dennis J.

Volltext

Copper-regulated Trafficking of the Menkes Disease Copper ATPase Is Associated with Formation of a Phosphorylated Catalytic Intermediate von Petris, Michael J, Voskoboinik, Ilia, Cater, Michael, Smith, Kathryn, Kim, Byung-Eun, Llanos, Roxana M, Strausak, Daniel, Camakaris, James, Mercer, Julian F B

Volltext