A new dimension to the Barker hypothesis: Low birthweight and susceptibility to renal disease von Hoy, Wendy E., Rees, Megan, Kile, Emma, Mathews, John D., Wang, Zhiqiang

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The multidimensional nature of renal disease: Rates and associations of albuminuria in an Australian Aboriginal community von Hoy, Wendy E., Mathews, John D., Mccredie, David A., Pugsley, David J., Hayhurst, Beverly G., Rees, Megan, Kile, Emma, Walker, Kate A., Wang, Zhiqiang

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Towards an epidemiologic definition of renal disease: Rates and associations of albuminuria in a high-risk Australian Aboriginal community von HOY, Wendy E, MATHEWS, John D, WANG, Zhiqiang, McCredie, David A, HAYHURST, Beverly G, PUGSLEY, David J, NORMAN, Robert J, McFarlane, Robert, REES, Megan, KILE, Emma, WALKER, Kate

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Two distinct pathways regulate platelet phosphatidylserine exposure and procoagulant function von Schoenwaelder, Simone M., Yuan, Yuping, Josefsson, Emma C., White, Michael J., Yao, Yu, Mason, Kylie D., O'Reilly, Lorraine A., Henley, Katya J., Ono, Akiko, Hsiao, Sarah, Willcox, Abbey, Roberts, Andrew W., Huang, David C.S., Salem, Hatem H., Kile, Benjamin T., Jackson, Shaun P.

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Platelet production proceeds independently of the intrinsic and extrinsic apoptosis pathways von Josefsson, Emma C., Burnett, Deborah L., Lebois, Marion, Debrincat, Marlyse A., White, Michael J., Henley, Katya J., Lane, Rachael M., Moujalled, Diane, Preston, Simon P., O’Reilly, Lorraine A., Pellegrini, Marc, Metcalf, Donald, Strasser, Andreas, Kile, Benjamin T.

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The Dendritic Cell Receptor Clec9A Binds Damaged Cells via Exposed Actin Filaments von Zhang, Jian-Guo, Czabotar, Peter E., Policheni, Antonia N., Caminschi, Irina, San Wan, Soo, Kitsoulis, Susie, Tullett, Kirsteen M., Robin, Adeline Y., Brammananth, Rajini, van Delft, Mark F., Lu, Jinhua, O'Reilly, Lorraine A., Josefsson, Emma C., Kile, Benjamin T., Chin, Wei Jin, Mintern, Justine D., Olshina, Maya A., Wong, Wilson, Baum, Jake, Wright, Mark D., Huang, David C.S., Mohandas, Narla, Coppel, Ross L., Colman, Peter M., Nicola, Nicos A., Shortman, Ken, Lahoud, Mireille H.

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Expansion of the neonatal platelet mass is achieved via an extension of platelet lifespan von Liu, Zhi-Jian, Hoffmeister, Karin M., Hu, Zhongbo, Mager, Donald E., Ait-Oudhia, Sihem, Debrincat, Marlyse A., Pleines, Irina, Josefsson, Emma C., Kile, Benjamin T., Italiano, Joseph, Ramsey, Haley, Grozovsky, Renata, Veng-Pedersen, Peter, Chavda, Chaitanya, Sola-Visner, Martha

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A lineage of diploid platelet-forming cells precedes polyploid megakaryocyte formation in the mouse embryo von Potts, Kathryn S., Sargeant, Tobias J., Markham, John F., Shi, Wei, Biben, Christine, Josefsson, Emma C., Whitehead, Lachlan W., Rogers, Kelly L., Liakhovitskaia, Anna, Smyth, Gordon K., Kile, Benjamin T., Medvinsky, Alexander, Alexander, Warren S., Hilton, Douglas J., Taoudi, Samir

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Bcl-xL–inhibitory BH3 mimetics can induce a transient thrombocytopathy that undermines the hemostatic function of platelets von Schoenwaelder, Simone M., Jarman, Kate E., Gardiner, Elizabeth E., Hua, My, Qiao, Jianlin, White, Michael J., Josefsson, Emma C., Alwis, Imala, Ono, Akiko, Willcox, Abbey, Andrews, Robert K., Mason, Kylie D., Salem, Hatem H., Huang, David C.S., Kile, Benjamin T., Roberts, Andrew W., Jackson, Shaun P.

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Deciphering the molecular and biologic processes that mediate histone deacetylase inhibitor–induced thrombocytopenia von Bishton, Mark J., Harrison, Simon J., Martin, Benjamin P., McLaughlin, Nicole, James, Chloé, Josefsson, Emma C., Henley, Katya J., Kile, Benjamin T., Prince, H. Miles, Johnstone, Ricky W.

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Megakaryocytes possess a functional intrinsic apoptosis pathway that must be restrained to survive and produce platelets von Josefsson, Emma C, James, Chloé, Henley, Katya J, Debrincat, Marlyse A, Rogers, Kelly L, Dowling, Mark R, White, Michael J, Kruse, Elizabeth A, Lane, Rachael M, Ellis, Sarah, Nurden, Paquita, Mason, Kylie D, O'Reilly, Lorraine A, Roberts, Andrew W, Metcalf, Donald, Huang, David C S, Kile, Benjamin T

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Proapoptotic Bak and Bax guard against fatal systemic and organ-specific autoimmune disease von Mason, Kylie D., Lin, Ann, Robb, Lorraine, Josefsson, Emma C., Henley, Katya J., Gray, Daniel H. D., Kile, Benjamin T., Roberts, Andrew W., Strasser, Andreas, Huang, David C. S., Waring, Paul, O'Reilly, Lorraine A.

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The EMT modulator SNAI1 contributes to AML pathogenesis via its interaction with LSD1 von Carmichael, Catherine L., Wang, Jueqiong, Nguyen, Thao, Kolawole, Oluseyi, Benyoucef, Aissa, De Mazière, Charlotte, Milne, Anna R., Samuel, Sona, Gillinder, Kevin, Hediyeh-zadeh, Soroor, Vo, Anh N.Q., Huang, Yizhou, Knezevic, Kathy, McInnes, William R.L., Shields, Benjamin J., Mitchell, Helen, Ritchie, Matthew E., Lammens, Tim, Lintermans, Beatrice, Van Vlierberghe, Pieter, Wong, Nicholas C., Haigh, Katharina, Thoms, Julie A.I., Toulmin, Emma, Curtis, David J., Oxley, Ethan P., Dickins, Ross A., Beck, Dominik, Perkins, Andrew, McCormack, Matthew P., Davis, Melissa J., Berx, Geert, Zuber, Johannes, Pimanda, John E., Kile, Benjamin T., Goossens, Steven, Haigh, Jody J.

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Apoptotic Ablation of Platelets Reduces Atherosclerosis in Mice With Diabetes von Lee, Man K.S., Kraakman, Michael J., Dragoljevic, Dragana, Hanssen, Nordin M.J., Flynn, Michelle C., Al-Sharea, Annas, Sreejit, Gopalkrishna, Bertuzzo-Veiga, Camilla, Cooney, Olivia D., Baig, Fatima, Morriss, Elizabeth, Cooper, Mark E., Josefsson, Emma C., Kile, Benjamin T., Nagareddy, Prabhakara R., Murphy, Andrew J.

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Dual requirement for the ETS transcription factors Fli-1 and Erg in hematopoietic stem cells and the megakaryocyte lineage von Kruse, Elizabeth A, Loughran, Stephen J, Baldwin, Tracey M, Josefsson, Emma C, Ellis, Sarah, Watson, Dennis K, Nurden, Paquita, Metcalf, Donald, Hilton, Douglas J, Alexander, Warren S, Kile, Benjamin T

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Recipient BCL2 inhibition and NK cell ablation form part of a reduced intensity conditioning regime that improves allo-bone marrow transplantation outcomes von Jiao, Yuhao, Davis, Joanne E., Rautela, Jai, Carrington, Emma M., Ludford-Menting, Mandy J., Goh, Wilford, Delconte, Rebecca B., Souza-Fonseca-Guimaraes, Fernando, Koldej, Rachel, Gray, Daniel, Huang, David, Kile, Ben T., Lew, Andrew M., Ritchie, David S., Huntington, Nicholas D.

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Intrinsic apoptosis circumvents the functional decline of circulating platelets but does not cause the storage lesion von Pleines, Irina, Lebois, Marion, Gangatirkar, Pradnya, Au, Amanda E., Lane, Rachael M., Henley, Katya J., Kauppi, Maria, Corbin, Jason, Cannon, Ping, Bernardini, Jonathan, Alwis, Imala, Jarman, Kate E., Ellis, Sarah, Metcalf, Donald, Jackson, Shaun P., Schoenwaelder, Simone M., Kile, Benjamin T., Josefsson, Emma C.

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A missense mutation in the MLKL brace region promotes lethal neonatal inflammation and hematopoietic dysfunction von Hildebrand, Joanne M., Kauppi, Maria, Majewski, Ian J., Liu, Zikou, Cox, Allison J., Miyake, Sanae, Petrie, Emma J., Silk, Michael A., Li, Zhixiu, Tanzer, Maria C., Brumatti, Gabriela, Young, Samuel N., Hall, Cathrine, Garnish, Sarah E., Corbin, Jason, Stutz, Michael D., Di Rago, Ladina, Gangatirkar, Pradnya, Josefsson, Emma C., Rigbye, Kristin, Anderton, Holly, Rickard, James A., Tripaydonis, Anne, Sheridan, Julie, Scerri, Thomas S., Jackson, Victoria E., Czabotar, Peter E., Zhang, Jian-Guo, Varghese, Leila, Allison, Cody C., Pellegrini, Marc, Tannahill, Gillian M., Hatchell, Esme C., Willson, Tracy A., Stockwell, Dina, de Graaf, Carolyn A., Collinge, Janelle, Hilton, Adrienne, Silke, Natasha, Spall, Sukhdeep K., Chau, Diep, Athanasopoulos, Vicki, Metcalf, Donald, Laxer, Ronald M., Bassuk, Alexander G., Darbro, Benjamin W., Fiatarone Singh, Maria A., Vlahovich, Nicole, Hughes, David, Kozlovskaia, Maria, Ascher, David B., Warnatz, Klaus, Venhoff, Nils, Thiel, Jens, Biben, Christine, Blum, Stefan, Reveille, John, Hildebrand, Michael S., Vinuesa, Carola G., McCombe, Pamela, Brown, Matthew A., Kile, Benjamin T., McLean, Catriona, Bahlo, Melanie, Masters, Seth L., Nakano, Hiroyasu, Ferguson, Polly J., Murphy, James M., Alexander, Warren S., Silke, John

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A model for studying the hemostatic consumption or destruction of platelets von Dowling, Mark R, Josefsson, Emma C, Henley, Katya J, Kile, Benjamin T, Hodgkin, Philip D

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Caspase-9 mediates the apoptotic death of megakaryocytes and platelets, but is dispensable for their generation and function von White, Michael J., Schoenwaelder, Simone M., Josefsson, Emma C., Jarman, Kate E., Henley, Katya J., James, Chloé, Debrincat, Marlyse A., Jackson, Shaun P., Huang, David C.S., Kile, Benjamin T.

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