Altered islet prohormone processing: a cause or consequence of diabetes? von Ramzy, Adam, Kieffer, Timothy J

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Closing in on Mass Production of Mature Human Beta Cells von Kieffer, Timothy J.

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Glucagon-like peptide-1: glucose homeostasis and beyond von Cho, Young Min, Fujita, Yukihiro, Kieffer, Timothy J

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Enrichment of human embryonic stem cell‐derived NKX6.1‐expressing pancreatic progenitor cells accelerates the maturation of insulin‐secreting cells in vivo von Rezania, Alireza, Bruin, Jennifer E., Xu, Jean, Narayan, Kavitha, Fox, Jessica K., O'Neil, John J., Kieffer, Timothy J.

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The glucoregulatory actions of leptin von D'Souza, Anna M, Neumann, Ursula H, Glavas, Maria M, Kieffer, Timothy J

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Targeting the glucagon receptor family for diabetes and obesity therapy von Cho, Young Min, Merchant, Catherine E, Kieffer, Timothy J

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Human Pluripotent Stem Cells to Model Islet Defects in Diabetes von Balboa, Diego, Iworima, Diepiriye G, Kieffer, Timothy J

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Reduced Insulin Production Relieves Endoplasmic Reticulum Stress and Induces β Cell Proliferation von Szabat, Marta, Page, Melissa M., Panzhinskiy, Evgeniy, Skovsø, Søs, Mojibian, Majid, Fernandez-Tajes, Juan, Bruin, Jennifer E., Bround, Michael J., Lee, Jason T.C., Xu, Eric E., Taghizadeh, Farnaz, O’Dwyer, Shannon, van de Bunt, Martijn, Moon, Kyung-Mee, Sinha, Sunita, Han, Jun, Fan, Yong, Lynn, Francis C., Trucco, Massimo, Borchers, Christoph H., Foster, Leonard J., Nislow, Corey, Kieffer, Timothy J., Johnson, James D.

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Protocol development to further differentiate and transition stem cell-derived pancreatic progenitors from a monolayer into endocrine cells in suspension culture von Braam, Mitchell J. S., Zhao, Jia, Liang, Shenghui, Ida, Shogo, Kloostra, Nick K., Iworima, Diepiriye G., Tang, Mei, Baker, Robert K., Quiskamp, Nina, Piret, James M., Kieffer, Timothy J.

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Initial cell seeding density influences pancreatic endocrine development during in vitro differentiation of human embryonic stem cells von Gage, Blair K, Webber, Travis D, Kieffer, Timothy J

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FGF21-Mediated Improvements in Glucose Clearance Require Uncoupling Protein 1 von Kwon, Michelle M., O’Dwyer, Shannon M., Baker, Robert K., Covey, Scott D., Kieffer, Timothy J.

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The Impact of Different Implantation Sites and Sex on the Differentiation of Human Pancreatic Endoderm Cells Into Insulin-Secreting Cells In Vivo von Saber, Nelly, Ellis, Cara E, Iworima, Diepiriye G, Baker, Robert K, Rezania, Alireza, Kieffer, Timothy J

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The Role of ARX in Human Pancreatic Endocrine Specification von Gage, Blair K, Asadi, Ali, Baker, Robert K, Webber, Travis D, Wang, Rennian, Itoh, Masayuki, Hayashi, Masaharu, Miyata, Rie, Akashi, Takumi, Kieffer, Timothy J

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PDX1+ cell budding morphogenesis in a stem cell-derived islet spheroid system von Zhao, Jia, Liang, Shenghui, Cen, Haoning Howard, Li, Yanjun, Baker, Robert K., Ruprai, Balwinder, Gao, Guang, Zhang, Chloe, Ren, Huixia, Tang, Chao, Chen, Liangyi, Liu, Yanmei, Lynn, Francis C., Johnson, James D., Kieffer, Timothy J.

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Differentiation of human pluripotent stem cells into β-cells: Potential and challenges von Quiskamp, Nina, Dr, Bruin, Jennifer E., Dr, Kieffer, Timothy J., Dr

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Accelerated Maturation of Human Stem Cell-Derived Pancreatic Progenitor Cells into Insulin-Secreting Cells in Immunodeficient Rats Relative to Mice von Bruin, Jennifer E., Asadi, Ali, Fox, Jessica K., Erener, Suheda, Rezania, Alireza, Kieffer, Timothy J.

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Dietary Fructose Reduces Circulating Insulin and Leptin, Attenuates Postprandial Suppression of Ghrelin, and Increases Triglycerides in Women von Teff, Karen L., Elliott, Sharon S., Tschöp, Matthias, Kieffer, Timothy J., Rader, Daniel, Heiman, Mark, Townsend, Raymond R., Keim, Nancy L., D’Alessio, David, Havel, Peter J.

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Process parameter development for the scaled generation of stem cell‐derived pancreatic endocrine cells von Iworima, Diepiriye G., Rieck, Sebastian, Kieffer, Timothy J.

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Revisiting Proinsulin Processing: Evidence That Human β-Cells Process Proinsulin With Prohormone Convertase (PC) 1/3 but Not PC2 von Ramzy, Adam, Asadi, Ali, Kieffer, Timothy J

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Metabolic switching, growth kinetics and cell yields in the scalable manufacture of stem cell-derived insulin-producing cells von Iworima, Diepiriye G, Baker, Robert K, Ellis, Cara, Sherwood, Chris, Zhan, Lisa, Rezania, Alireza, Piret, James M, Kieffer, Timothy J

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