Diverse human astrocyte and microglial transcriptional responses to Alzheimer’s pathology von Smith, Amy M., Davey, Karen, Tsartsalis, Stergios, Khozoie, Combiz, Fancy, Nurun, Tang, See Swee, Liaptsi, Eirini, Weinert, Maria, McGarry, Aisling, Muirhead, Robert C. J., Gentleman, Steve, Owen, David R., Matthews, Paul M.

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A single nuclear transcriptomic characterisation of mechanisms responsible for impaired angiogenesis and blood-brain barrier function in Alzheimer’s disease von Tsartsalis, Stergios, Sleven, Hannah, Fancy, Nurun, Wessely, Frank, Smith, Amy M., Willumsen, Nanet, Cheung, To Ka Dorcas, Rokicki, Michal J., Chau, Vicky, Ifie, Eseoghene, Khozoie, Combiz, Ansorge, Olaf, Yang, Xin, Jenkyns, Marion H., Davey, Karen, McGarry, Aisling, Muirhead, Robert C. J., Debette, Stephanie, Jackson, Johanna S., Montagne, Axel, Owen, David R., Miners, J. Scott, Love, Seth, Webber, Caleb, Cader, M. Zameel, Matthews, Paul M.

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Cell Wall Perturbation Sensitizes Fungi to the Antimalarial Drug Chloroquine von ISLAHUDIN, Farida, KHOZOIE, Combiz, BATES, Steven, TING, Kang-Nee, PLEASS, Richard J, AVERY, Simon V

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The Antimalarial Drug Quinine Disrupts Tat2p-mediated Tryptophan Transport and Causes Tryptophan Starvation von Khozoie, Combiz, Pleass, Richard J., Avery, Simon V.

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Analysis of the peroxisome proliferator-activated receptor-β/δ (PPARβ/δ) cistrome reveals novel co-regulatory role of ATF4 von Khozoie, Combiz, Borland, Michael G, Zhu, Bokai, Baek, Songjoon, John, Sam, Hager, Gordon L, Shah, Yatrik M, Gonzalez, Frank J, Peters, Jeffrey M

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Peroxisome Proliferator-Activated Receptor β/δ Cross Talks with E2F and Attenuates Mitosis in HRAS-Expressing Cells von Zhu, Bokai, Khozoie, Combiz, Bility, Moses T., Ferry, Christina H., Blazanin, Nicholas, Glick, Adam B., Gonzalez, Frank J., Peters, Jeffrey M.

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Single‐nuclei RNA sequencing provides evidence for glial senescence in Alzheimer’s disease von Fancy, Nurun N, Smith, Amy, Tsartsalis, Stergios, Muirhead, Robert, Chau, Vicky, Davey, Karen, Mcgarry, Aisling, Khozoie, Combiz, Willumsen, Nanet, Zhang, Xiaowen, Jackson, Johanna, Matthews, Paul M, Jenkyns, Marion

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Characterisation of premature cell senescence in Alzheimer’s disease using single nuclear transcriptomics von Fancy, Nurun N., Smith, Amy M., Caramello, Alessia, Tsartsalis, Stergios, Davey, Karen, Muirhead, Robert C. J., McGarry, Aisling, Jenkyns, Marion H., Schneegans, Eleonore, Chau, Vicky, Thomas, Michael, Boulger, Sam, Cheung, To Ka Dorcas, Adair, Emily, Papageorgopoulou, Marianna, Willumsen, Nanet, Khozoie, Combiz, Gomez-Nicola, Diego, Jackson, Johanna S., Matthews, Paul M.

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Glial and neuronal mechanisms contributing to differential risks in TREM2 R47H and R62H variants in Alzheimer’s Disease von Fancy, Nurun N, Willumsen, Nanet, Tsartsalis, Stergios, Khozoie, Combiz, Mcgarry, Aisling, Muirhead, Robert, Schneegans, Eleonore, Davey, Karen, Chau, Vicky, Smith, Amy, Thomas, Michael, Scotton, William J., Hardy, John A., Huh, Dann, Jackson, Johanna, Matthews, Paul M

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Signalling pathways associated with impaired angiogenesis in Alzheimer’s Disease von Tsartsalis, Stergios, Sleven, Hannah, Fancy, Nurun N, Wessely, Frank, Willumsen, Nanet, Michal, Rokicki, Chau, Vicky, Ifie, Eseoghene, Khozoie, Combiz, Ansorge, Olaf, Owen, David R, Webber, Caleb, Jackson, Johanna, Cader, Zameel, Matthews, Paul M

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Efficacy of arginine depletion by ADI-PEG20 in an intracranial model of GBM von Przystal, Justyna Magdalena, Hajji, Nabil, Khozoie, Combiz, Renziehausen, Alexander, Zeng, Qingyu, Abaitua, Fernando, Hajitou, Amin, Suwan, Keittisak, Want, Elizabeth, Bomalaski, John, Szlosarek, Peter, O’Neill, Kevin, Crook, Tim, Syed, Nelofer

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PPARβ/δ promotes HRAS-induced senescence and tumor suppression by potentiating p-ERK and repressing p-AKT signaling von Zhu, B, Ferry, C H, Blazanin, N, Bility, M T, Khozoie, C, Kang, B-H, Glick, A B, Gonzalez, F J, Peters, J M

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EG-01EPIGENETIC INACTIVATION OF ARGININE BIOSYNTHESIS PATHWAY IN PAEDIATRIC HIGH GRADE GLIOMA von Channathodiyil, Prasanna, Kardooni, Hoda, Khozoie, Combiz, Nelofer, Syed, Darling, John, Morris, Mark, Warr, Tracy

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Stable over-expression of PPARβ/δ and PPARγ to examine receptor signaling in human HaCaT keratinocytes von Borland, Michael G., Khozoie, Combiz, Albrecht, Prajakta P., Zhu, Bokai, Lee, Christina, Lahoti, Tejas S., Gonzalez, Frank J., Peters, Jeffrey M.

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PPARβ/δ modulates ethanol-induced hepatic effects by decreasing pyridoxal kinase activity von Goudarzi, Maryam, Koga, Takayuki, Khozoie, Combiz, Mak, Tytus D, Kang, Boo-Hyon, Jr, Albert J. Fornace, Peters, Jeffrey M

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EG-01 EPIGENETIC INACTIVATION OF ARGININE BIOSYNTHESIS PATHWAY IN PAEDIATRIC HIGH GRADE GLIOMA von Channathodiyil, P., Kardooni, H., Khozoie, C., Nelofer, S., Darling, J., Morris, M., Warr, T.

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Supplemental_File_scflow_reports.zip von Khozoie, Combiz

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human_10x_imperial.zip von Combiz Khozoie

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ctd_v1.zip von Combiz Khozoie

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Abstract 2172: Anti-oncogenic role of peroxisome proliferator-activated receptor-α/β (PPARδ/α) involves inhibition of mitosis and regulation of Hras1-induced senescence von Zhu, Bokai, Khozoie, Combiz, Ferry, Christina H., Markell, Lauren M., Bility, Moses T., Blazanin, Nicholas, Glick, Adam B., Gonzalez, Frank J.

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