Design, Synthesis, Evaluation, and Structural Studies of C2-Symmetric Small Molecule Inhibitors of Programmed Cell Death-1/Programmed Death-Ligand 1 Protein-Protein Interaction von Basu, Subhadwip, Yang, Jeffrey, Xu, Bin, Magiera-Mularz, Katarzyna, Skalniak, Lukasz, Musielak, Bogdan, Kholodovych, Vladyslav, Holak, Tad A, Hu, Longqin

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Sugar-based amphiphilic nanoparticles arrest atherosclerosis in vivo von Lewis, Daniel R., Petersen, Latrisha K., York, Adam W., Zablocki, Kyle R., Joseph, Laurie B., Kholodovych, Vladyslav, Prud’homme, Robert K., Uhrich, Kathryn E., Moghe, Prabhas V.

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Requirement of Gamma-Carboxyglutamic Acid Modification and Phosphatidylserine Binding for the Activation of Tyro3, Axl, and Mertk Receptors by Growth Arrest-Specific 6 von Geng, Ke, Kumar, Sushil, Kimani, Stanley G, Kholodovych, Vladyslav, Kasikara, Canan, Mizuno, Kensaku, Sandiford, Oleta, Rameshwar, Pranela, Kotenko, Sergei V, Birge, Raymond B

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Genome assembly and geospatial phylogenomics of the bed bug Cimex lectularius von Rosenfeld, Jeffrey A., Reeves, Darryl, Brugler, Mercer R., Narechania, Apurva, Simon, Sabrina, Durrett, Russell, Foox, Jonathan, Shianna, Kevin, Schatz, Michael C., Gandara, Jorge, Afshinnekoo, Ebrahim, Lam, Ernest T., Hastie, Alex R., Chan, Saki, Cao, Han, Saghbini, Michael, Kentsis, Alex, Planet, Paul J., Kholodovych, Vladyslav, Tessler, Michael, Baker, Richard, DeSalle, Rob, Sorkin, Louis N., Kolokotronis, Sergios-Orestis, Siddall, Mark E., Amato, George, Mason, Christopher E.

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Mapping Soluble Guanylyl Cyclase and Protein Disulfide Isomerase Regions of Interaction von Heckler, Erin J, Kholodovych, Vladyslav, Jain, Mohit, Liu, Tong, Li, Hong, Beuve, Annie

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Human Pregnane X Receptor Antagonists and Agonists Define Molecular Requirements for Different Binding Sites von Ekins, Sean, Chang, Cheng, Mani, Sridhar, Krasowski, Matthew D, Reschly, Erica J, Iyer, Manisha, Kholodovych, Vladyslav, Ai, Ni, Welsh, William J, Sinz, Michael, Swaan, Peter W, Patel, Rachana, Bachmann, Kenneth

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Computational Discovery of Novel Low Micromolar Human Pregnane X Receptor Antagonists von Ekins, Sean, Kholodovych, Vladyslav, Ai, Ni, Sinz, Michael, Gal, Joseph, Gera, Lajos, Welsh, William J, Bachmann, Kenneth, Mani, Sridhar

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CD36‐Binding Amphiphilic Nanoparticles for Attenuation of α‐Synuclein‐Induced Microglial Activation von Zhao, Nanxia, Francis, Nicola L., Song, Shuang, Kholodovych, Vladyslav, Calvelli, Hannah R., Hoop, Cody L., Pang, Zhiping P., Baum, Jean, Uhrich, Kathryn E., Moghe, Prabhas V.

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Highly Chlorinated PCBs Inhibit the Human Xenobiotic Response Mediated by the Steroid and Xenobiotic Receptor (SXR) von Tabb, Michelle M., Kholodovych, Vladyslav, Grün, Felix, Zhou, Changcheng, Welsh, William J., Blumberg, Bruce

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The Major Human Pregnane X Receptor (PXR) Splice Variant, PXR.2, Exhibits Significantly Diminished Ligand-Activated Transcriptional Regulation von Lin, Yvonne S., Yasuda, Kazuto, Assem, Mahfoud, Cline, Cynthia, Barber, Joe, Li, Chia-Wei, Kholodovych, Vladyslav, Ai, Ni, Chen, J. Don, Welsh, William J., Ekins, Sean, Schuetz, Erin G.

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Specific Interactions between the Viral Coreceptor CXCR4 and the Biguanide-Based Compound NB325 Mediate Inhibition of Human Immunodeficiency Virus Type 1 Infection von THAKKAR, Nina, PIRRONE, Vanessa, PASSIC, Shendra, WEI ZHU, KHOLODOVYCH, Vladyslav, WELSH, William, RANDO, Robert F, LABIB, Mohamed E, WIGDAHL, Brian, KREBS, Fred C

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Persistent Interactions between Biguanide-Based Compound NB325 and CXCR4 Result in Prolonged Inhibition of Human Immunodeficiency Virus Type 1 Infection von THAKKAR, Nina, PIRRONE, Vanessa, KREBS, Fred C, PASSIC, Shendra, KEOGAN, Shawn, WEI ZHU, KHOLODOVYCH, Vladyslav, WELSH, William, RANDO, Robert, LABIB, Mohamed, WIGDAHL, Brian

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The tumor neomatrix component fibrillin-1 (FBN1) is a druggable oncologically relevant target: Proof-of-principle in vitro using an FDA-approved medicine as pioneer inhibitor of pr... von Cracchiolo, Isabel, Singh, Sukhwinder, Sandev, Angela, Cracchiolo, Bernadette, Hanauske, Axel-Rainer, Kholodovych, Vladyslav, Hanauske-Abel, Hartmut

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Self-assembled Cationic Amphiphiles as Antimicrobial Peptides Mimics: Role of Hydrophobicity, Linkage Type, and Assembly State von Zhang, Yingyue, Algburi, Ammar, Wang, Ning, Kholodovych, Vladyslav, Oh, Drym O, Chikindas, Michael, Uhrich, Kathryn E

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Guanylyl cyclase sensitivity to nitric oxide is protected by a thiol oxidation-driven interaction with thioredoxin-1 von Huang, Can, Alapa, Maryam, Shu, Ping, Nagarajan, Narayani, Wu, Changgong, Sadoshima, Junichi, Kholodovych, Vladyslav, Li, Hong, Beuve, Annie

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Design, synthesis, and evaluation of l-cystine diamides as l-cystine crystallization inhibitors for cystinuria von Yang, Yanhui, Albanyan, Haifa, Lee, Sumi, Aloysius, Herve, Liang, Jian-Jie, Kholodovych, Vladyslav, Sahota, Amrik, Hu, Longqin

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Carbohydrate-derived amphiphilic macromolecules: a biophysical structural characterization and analysis of binding behaviors to model membranes von Martin, Adriana A T, Tomasini, Michael, Kholodovych, Vladyslav, Gu, Li, Sommerfeld, Sven Daniel, Uhrich, Kathryn E, Murthy, N Sanjeeva, Welsh, William J, Moghe, Prabhas V

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Online chemical modeling environment (OCHEM): web platform for data storage, model development and publishing of chemical information von Sushko, Iurii, Novotarskyi, Sergii, Körner, Robert, Pandey, Anil Kumar, Rupp, Matthias, Teetz, Wolfram, Brandmaier, Stefan, Abdelaziz, Ahmed, Prokopenko, Volodymyr V., Tanchuk, Vsevolod Y., Todeschini, Roberto, Varnek, Alexandre, Marcou, Gilles, Ertl, Peter, Potemkin, Vladimir, Grishina, Maria, Gasteiger, Johann, Schwab, Christof, Baskin, Igor I., Palyulin, Vladimir A., Radchenko, Eugene V., Welsh, William J., Kholodovych, Vladyslav, Chekmarev, Dmitriy, Cherkasov, Artem, Aires-de-Sousa, Joao, Zhang, Qing-You, Bender, Andreas, Nigsch, Florian, Patiny, Luc, Williams, Antony, Tkachenko, Valery, Tetko, Igor V.

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Identification of novel S-nitrosation sites in soluble guanylyl cyclase, the nitric oxide receptor von Beuve, Annie, Wu, Changgong, Cui, Chuanlong, Liu, Tong, Jain, Mohit Raja, Huang, Can, Yan, Lin, Kholodovych, Vladyslav, Li, Hong

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Human Lutropin (hLH) and Choriogonadotropin (CG) Are Assembled by Different Pathways von Bernard, Michael P., Lin, Win, Kholodovych, Vladyslav, Moyle, William R.

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