Ligand-Induced Degradation of a CAR Permits Reversible Remote Control of CAR T Cell Activity In Vitro and In Vivo von Richman, Sarah A., Wang, Liang-Chuan, Moon, Edmund K., Khire, Uday R., Albelda, Steven M., Milone, Michael C.

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Ligand-Induced Degradation of a CAR Permits Reversible Remote Control of CAR T Cell Activity In Vitro and In Vivo von Richman, Sarah A., Wang, Liang-Chuan, Moon, Edmund K., Khire, Uday R., Albelda, Steven M., Milone, Michael C.

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Macrocyclic MEK1/2 inhibitor with efficacy in a mouse model of cardiomyopathy caused by lamin A/C gene mutation von Wu, Wei, Chordia, Mahendra D., Hart, Barry P., Kumarasinghe, E. Sathyajith, Ji, Min K., Bhargava, Ajay, Lawlor, Michael W., Shin, Ji-Yeon, Sera, Fusako, Homma, Shunichi, Muchir, Antoine, Khire, Uday R., Worman, Howard J.

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Quinazolinone Derivatives as Orally Available Ghrelin Receptor Antagonists for the Treatment of Diabetes and Obesity von Rudolph, Joachim, Esler, William P, O'Connor, Stephen, Coish, Philip D. G, Wickens, Philip L, Brands, Michael, Bierer, Donald E, Bloomquist, Brian T, Bondar, Georgiy, Chen, Libing, Chuang, Chih-Yuan, Claus, Thomas H, Fathi, Zahra, Fu, Wenlang, Khire, Uday R, Kristie, James A, Liu, Xiao-Gao, Lowe, Derek B, McClure, Andrea C, Michels, Martin, Ortiz, Astrid A, Ramsden, Philip D, Schoenleber, Robert W, Shelekhin, Tatiana E, Vakalopoulos, Alexandros, Tang, Weifeng, Wang, Lei, Yi, Lin, Gardell, Stephen J, Livingston, James N, Sweet, Laurel J, Bullock, William H

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Total Synthesis of the Polyene Macrolide Roflamycoin von Rychnovsky, Scott D, Khire, Uday R, Yang, Guang

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Omega-carboxypyridyl substituted ureas as Raf kinase inhibitors: SAR of the amide substituent von Khire, Uday R., Bankston, Donald, Barbosa, James, Brittelli, David R., Caringal, Yolanda, Carlson, Robert, Dumas, Jacques, Gane, Todd, Heald, Sarah L., Hibner, Barbara, Johnson, Jeffrey S., Katz, Michael E., Kennure, Nancy, Kingery-Wood, Jill, Lee, Wendy, Liu, Xiao-Gao, Lowinger, Timothy B., McAlexander, Ian, Monahan, Mary-Katherine, Natero, Reina, Renick, Joel, Riedl, Bernd, Rong, Hong, Sibley, Robert N., Smith, Roger A., Wolanin, Donald

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SAR of a novel ‘Anthranilamide Like’ series of VEGFR-2, multi protein kinase inhibitors for the treatment of cancer von Wickens, Philip, Kluender, Harold, Dixon, Julie, Brennan, Catherine, Achebe, Furahi, Bacchiocchi, Antonella, Bankston, Don, Bierer, Donald, Brands, Michael, Braun, Debbie, Brown, Melissa S., Chuang, Chih-Yuan, Dumas, Jacques, Enyedy, Istvan, Hofilena, Gloria, Hong, Zhenqiu, Housley, Tim, Jones, Benjamin, Khire, Uday, Kreiman, Charles, Kumarasinghe, Ellalahewage, Lowinger, Timothy, Ott-Morgan, Ronda, Perkins, Louise, Phillips, Barton, Schoenleber, Robert, Scott, William J., Sheeler, Ryan, Redman, Anikó, Sun, Xiuying, Taylor, Ian, Wang, Lei, Wilhelm, Scott, Zhang, Xiaomei, Zhang, Mingbao, Sullivan, Elizabeth, Carter, Christopher, Miglarese, Mark, Levy, Joan

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Prins Desymmetrization of a C 2-Symmetric Diol:  Application to the Synthesis of 17-Deoxyroflamycoin von Rychnovsky, Scott D, Yang, Guang, Hu, Yueqing, Khire, Uday R

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B-(.gamma.-(Trimethylsilyl)propargyl)diisopinocampheylborane: A New, Highly Efficient Reagent for the Enantioselective Propargylboration of Aldehydes. Synthesis of Trimethylsilyl-S... von Brown, Herbert C, Khire, Uday R, Narla, Gowriswari

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Abstract 736: Novel, potent MEK inhibitor CIP-1374 for the treatment of cancer von Chordia, Mahendra, Khire, Uday, Bhargava, Ajay

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Inhibition of Macrophage Migration Inhibitory Factor by a Chimera of Two Allosteric Binders von Cirillo, Pier F, Asojo, Oluwatoyin A, Khire, Uday, Lee, Yashang, Mootien, Sara, Hegan, Peter, Sutherland, Alan G, Peterson-Roth, Elizabeth, Ledizet, Michel, Koski, Raymond A, Anthony, Karen G

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First International Conference on RASopathies and Neurofibromatoses in Asia: Identification and advances of new therapeutics von Rauen, Katherine A., Alsaegh, Abeer, Ben‐Shachar, Shay, Berman, Yemima, Blakeley, Jaishri, Cordeiro, Isabel, Elgersma, Ype, Evans, D. Gareth, Fisher, Michael J., Frayling, Ian M., George, Joshi, Huson, Susan M., Kerr, Bronwyn, Khire, Uday, Korf, Bruce, Legius, Eric, Messiaen, Ludwine, van Minkelen, Rick, Nampoothiri, Sheela, Ngeow, Joanne, Parada, Luis F., Phadke, Shubha, Pillai, Ashok, Plotkin, Scott R., Puri, Ratna, Raji, Anup, Ramesh, Vijaya, Ratner, Nancy, Shankar, Suma P., Sharda, Sheetal, Tambe, Anant, Vikkula, Miikka, Widemann, Brigitte C., Wolkenstein, Pierre, Upadhyaya, Meena

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Organoboranes for Synthesis. 15. B-Allenyl-9-BBN: A Highly Regiospecific and Chemoselective Reagent for Allenylboration of Representative Carbonyl Compounds, Leading to Homoproparg... von Brown, Herbert C, Khire, Uday R, Narla, Gowriswari, Racherla, Uday S

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Abstract 5470: Potent MEK inhibitor CIP-137401: Preclinical studies von Khire, Uday R., Bhargava, Ajay, Hart, Barry, Chordia, Mahendra D.

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First International Conference on RASopathies and Neurofibromatoses in Asia: Identification and advances of new therapeutics von Rauen, Katherine A, Alsaegh, Abeer, Ben-Shachar, Shay, Berman, Yemima, Blakeley, Jaishri, Cordeiro, Isabel, Elgersma, Ype, Evans, D. Gareth, Fisher, Michael J, Frayling, Ian M, George, Joshi, Huson, Susan M, Kerr, Bronwyn, Khire, Uday, Korf, Bruce, Legius, Eric, Messiaen, Ludwine, van Minkelen, Rick, Nampoothiri, Sheela, Ngeow, Joanne, Parada, Luis F, Phadke, Shubha, Pillai, Ashok, Plotkin, Scott R, Puri, Ratna, Raji, Anup, Ramesh, Vijaya, Ratner, Nancy, Shankar, Suma P, Sharda, Sheetal, Tambe, Anant, Vikkula, Miikka, Widemann, Brigitte C, Wolkenstein, Pierre, Upadhyaya, Meena

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Prins Desymmetrization of a C(2)-Symmetric Diol: Application to the Synthesis of 17-Deoxyroflamycoin von Rychnovsky, Scott D., Yang, Guang, Hu, Yueqing, Khire, Uday R.

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Prins Desymmetrization of a C2-Symmetric Diol:  Application to the Synthesis of 17-Deoxyroflamycoin von RYCHNOVSKY, Scott D., YANG, Guang, HU, Yueqing, KHIRE, Uday R.

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Convergent synthesis of a polyol chain with 4-acetoxy-1,3-dioxanes using a 1,1-bis((trimethylsilyl)methyl)ethene linchpin von Rychnovsky, Scott D., Fryszman, Olga, Khire, Uday R.

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Synthesis and pharmacological characterization of a potent, orally active p38 kinase inhibitor von Dumas, Jacques, Hatoum-Mokdad, Holia, Sibley, Robert N, Smith, Roger A, Scott, William J, Khire, Uday, Lee, Wendy, Wood, Jill, Wolanin, Donald, Cooley, Jeffrey, Bankston, Donald, Redman, Aniko M, Schoenleber, Robert, Caringal, Yolanda, Gunn, David, Romero, Romulo, Osterhout, Martin, Paulsen, Holger, Housley, Timothy J, Wilhelm, Scott M, Pirro, John, Chien, Du-Shieng, Ranges, Gerald E, Shrikhande, Alka, Muzsi, Andrew, Bortolon, Elizabeth, Wakefield, Jean, Gianpaolo Ostravage, Cynthia, Bhargava, Ajay, Chau, Thuy

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NOVEL MEK INHIBITORS, USEFUL IN THE TREATMENT OF DISEASES von KHIRE, UDAY R, CHORDIA, MAHENDRA DEVICHAND

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