Targeted therapy of esophageal squamous cell carcinoma: the NRF2 signaling pathway as target von Ma, Shaohua, Paiboonrungruan, Chorlada, Yan, Tiansheng, Williams, Kevin P., Major, M. Ben, Chen, Xiaoxin Luke

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Identification of Novel GANT61 Analogs with Activity in Hedgehog Functional Assays and GLI1-Dependent Cancer Cells von Abu Rabe, Dina, Chdid, Lhoucine, Lamson, David R, Laudeman, Christopher P, Tarpley, Michael, Elsayed, Naglaa, Smith, Ginger R, Zheng, Weifan, Dixon, Maria S, Williams, Kevin P

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Identification of a DYRK1A-mediated phosphorylation site within the nuclear localization sequence of the hedgehog transcription factor GLI1 von Ehe, Ben K., Lamson, David R., Tarpley, Michael, Onyenwoke, Rob U., Graves, Lee M., Williams, Kevin P.

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Unveiling the antiglioblastoma potential of harmicens, harmine and ferrocene hybrids von Poje, Goran, Šakić, Davor, Marinović, Marina, You, Jiangyang, Tarpley, Michael, Williams, Kevin P., Golub, Nikolina, Dernovšek, Jaka, Tomašič, Tihomir, Bešić, Erim, Rajić, Zrinka

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Literature-Wide Association Studies (LWAS) for a Rare Disease: Drug Repurposing for Inflammatory Breast Cancer von Ji, Xiaojia, Jin, Chunming, Dong, Xialan, Dixon, Maria S, Williams, Kevin P, Zheng, Weifan

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Applying a Gene Reversal Rate Computational Methodology to Identify Drugs for a Rare Cancer: Inflammatory Breast Cancer von Ji, Xiaojia, Williams, Kevin P, Zheng, Weifan

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Small molecule screen identifies pyrimethamine as an inhibitor of NRF2-driven esophageal hyperplasia von Paiboonrungruang, Chorlada, Xiong, Zhaohui, Lamson, David, Li, Yahui, Bowman, Brittany, Chembo, Julius, Huang, Caizhi, Li, Jianying, Livingston, Eric W., Frank, Jon E., Chen, Vivian, Li, Yong, Weissman, Bernard, Yuan, Hong, Williams, Kevin P., Ben Major, M., Chen, Xiaoxin

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Adaptive stress response genes associated with breast cancer subtypes and survival outcomes reveal race-related differences von Al Abo, Muthana, Gearhart-Serna, Larisa, Van Laere, Steven, Freedman, Jennifer A., Patierno, Steven R., Hwang, Eun-Sil Shelley, Krishnamurthy, Savitri, Williams, Kevin P., Devi, Gayathri R.

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Optimization and validation of a DYRK1A TR-FRET assay for high-throughput screening von Tarpley, Michael, Caligan, Thomas B., Onyenwoke, Rob U., Williams, Kevin P.

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Data supporting a pilot high-throughput screen of a drug library for identification of DYRK1A inhibitors and high-content imaging analysis of identified harmine analogs von Tarpley, Michael, Oladapo, Helen, Caligan, Thomas B., Onyenwoke, Rob U., Williams, Kevin P.

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Perspectives on Inflammatory Breast Cancer (IBC) Research, Clinical Management and Community Engagement from the Duke IBC Consortium von Devi, Gayathri R, Hough, Holly, Barrett, Nadine, Cristofanilli, Massimo, Overmoyer, Beth, Spector, Neil, Ueno, Naoto T, Woodward, Wendy, Kirkpatrick, John, Vincent, Benjamin, Williams, Kevin P, Finley, Charlotte, Duff, Brandi, Worthy, Valarie, McCall, Shannon, Hollister, Beth A, Palmer, Greg, Force, Jeremy, Westbrook, Kelly, Fayanju, Oluwadamilola, Suneja, Gita, Dent, Susan F, Hwang, E Shelley, Patierno, Steven R, Marcom, P Kelly

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Cannabinoids Exacerbate Alcohol Teratogenesis by a CB1-Hedgehog Interaction von Fish, Eric W., Murdaugh, Laura B., Zhang, Chengjin, Boschen, Karen E., Boa-Amponsem, Oswald, Mendoza-Romero, Haley N., Tarpley, Michael, Chdid, Lhoucine, Mukhopadhyay, Somnath, Cole, Gregory J., Williams, Kevin P., Parnell, Scott E.

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Development and validation of a hedgehog heparin-binding assay for high-throughput screening von Lamson, David R., Hughes, Mark A., Adcock, Audrey F., Smith, Ginger R., Williams, Kevin P.

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An innovative educational program for addressing health disparities in translational cancer research von Oldham, Carla E, Gathings, M J, Devi, Gayathri R, Patierno, Steven R, Williams, Kevin P, Hough, Holly J, Barrett, Nadine J

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Differential effects of arsenic trioxide on chemosensitization in human hepatic tumor and stellate cell lines von Rangwala, Fatima, Williams, Kevin P, Smith, Ginger R, Thomas, Zainab, Allensworth, Jennifer L, Lyerly, H Kim, Diehl, Anna Mae, Morse, Michael A, Devi, Gayathri R

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Ethanol and Cannabinoids Regulate Zebrafish GABAergic Neuron Development and Behavior in a Sonic Hedgehog and Fibroblast Growth Factor‐Dependent Mechanism von Boa‐Amponsem, Oswald, Zhang, Chengjin, Burton, Derek, Williams, Kevin P., Cole, Gregory J.

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Antibody blockade of the Cripto CFC domain suppresses tumor cell growth in vivo von Adkins, Heather B, Bianco, Caterina, Schiffer, Susan G, Rayhorn, Paul, Zafari, Mohammad, Cheung, Anne E, Orozco, Olivia, Olson, Dian, De Luca, Antonella, Chen, Ling Ling, Miatkowski, Konrad, Benjamin, Chris, Normanno, Nicola, Williams, Kevin P, Jarpe, Matthew, LePage, Doreen, Salomon, David, Sanicola, Michele

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Maximizing binding capacity for protein A chromatography von Ghose, Sanchayita, Zhang, Jennifer, Conley, Lynn, Caple, Ryan, Williams, Kevin P., Cecchini, Douglas

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Identification of harmine and β-carboline analogs from a high-throughput screen of an approved drug collection; profiling as differential inhibitors of DYRK1A and monoamine oxidase... von Tarpley, Michael, Oladapo, Helen O., Strepay, Dillon, Caligan, Thomas B., Chdid, Lhoucine, Shehata, Hassan, Roques, Jose R., Thomas, Rhashad, Laudeman, Christopher P., Onyenwoke, Rob U., Darr, David B., Williams, Kevin P.

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Lapatinib-induced annexin A6 upregulation as an adaptive response of triple-negative breast cancer cells to EGFR tyrosine kinase inhibitors von Widatalla, Sarrah E, Korolkova, Olga Y, Whalen, Diva S, Goodwin, J Shawn, Williams, Kevin P, Ochieng, Josiah, Sakwe, Amos M

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