A Randomized Trial of Genotype-Guided Dosing of Warfarin von Pirmohamed, Munir, Burnside, Girvan, Eriksson, Niclas, Jorgensen, Andrea L, Toh, Cheng Hock, Nicholson, Toby, Kesteven, Patrick, Christersson, Christina, Wahlström, Bengt, Stafberg, Christina, Zhang, J. Eunice, Leathart, Julian B, Kohnke, Hugo, Maitland-van der Zee, Anke H, Williamson, Paula R, Daly, Ann K, Avery, Peter, Kamali, Farhad, Wadelius, Mia

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Oral direct thrombin inhibitors or oral factor Xa inhibitors for the treatment of deep vein thrombosis von Robertson, Lindsay, Kesteven, Patrick, McCaslin, James E, Robertson, Lindsay

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Association of polymorphisms in the cytochrome P450 CYP2C9 with warfarin dose requirement and risk of bleeding complications von Aithal, Guruprasad P, Day, Christopher P, Kesteven, Patrick JL, Daly, Ann K

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The impact of CYP2C9 and VKORC1 genetic polymorphism and patient characteristics upon warfarin dose requirements: proposal for a new dosing regimen von Sconce, Elizabeth A., Khan, Tayyaba I., Wynne, Hilary A., Avery, Peter, Monkhouse, Louise, King, Barry P., Wood, Peter, Kesteven, Patrick, Daly, Ann K., Kamali, Farhad

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Contribution of age, body size, and CYP2C9 genotype to anticoagulant response to warfarin von Kamali, Farhad, Khan, Tayyaba Irfan, King, Barry P., Frearson, Richard, Kesteven, Patrick, Wood, Peter, Daly, Ann K., Wynne, Hilary

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Oral direct thrombin inhibitors or oral factor Xa inhibitors for the treatment of pulmonary embolism von Robertson, Lindsay, Kesteven, Patrick, McCaslin, James E, Robertson, Lindsay

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Comparison of D-dimer point of care test (POCT) against current laboratory test in patients with suspected venous thromboembolism (VTE) presenting to the emergency department (ED) von Sen, Basav, Kesteven, Patrick, Avery, Peter

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Impact of age on long‐term anticoagulation and how gender and monitoring setting affect it: implications for decision making and patient management von Abohelaika, Salah, Wynne, Hilary, Avery, Peter, Robinson, Brian, Kesteven, Patrick, Kamali, Farhad

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Tissue factor expression in monocyte subsets during human immunothrombosis, endotoxemia and sepsis von Musgrave, Kathryn M., Scott, Jonathan, Sendama, Wezi, Gardner, Aaron I., Dewar, Fiona, Lake, Cameron J., Spronk, Henri M.H., van Oerle, Rene, Visser, Mayken, ten Cate, Hugo, Kesteven, Patrick, Fuller, Andrew, McDonald, David, Knill, Carly, Hulme, Gillian, Filby, Andrew, Wright, Stephen E., Roy, Alistair I., Ruchaud-Sparagano, Marie-Hélène, Simpson, A. John, Rostron, Anthony J.

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The role of strain gauge plethysmography in the assessment of patients with suspected deep vein thrombosis von Robinson, Brian J., Kesteven, Patrick J. L., Elliott, Simon T.

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Rare missense variants in Tropomyosin‐4 (TPM4) are associated with platelet dysfunction, cytoskeletal defects, and excessive bleeding von Stapley, Rachel J., Poulter, Natalie S., Khan, Abdullah O., Smith, Christopher W., Bignell, Patricia, Fratter, Carl, Lester, Will, Lowe, Gillian, Morgan, Neil V., Morgan, Neil, Watson, Steve, Harrison, Paul, Lordkipanidze, Marie, Mumford, Andrew D., Mundell, Stuart J., Gissen, Paul, Daly, Martina E., Clark, Justin, Williams, Mike, Motwani, Jayashree, Marshall, Dianne, Lawson, Natalie, Nyatanga, Priscilla, Mann, Pat, Kirwan, Julie, Percy, Charles, Green, Pam, Hupston, Helen, Nagapachetty, Koomaravel, Dwenger, Elizabeth, Rourke, Ann O, Pope, Martin, Edmead, Camillia, Greenway, April, Makris, Michael, Payne, Jeanette, Pavord, Sue, Gooding, Richard, Dattani, Rashesh, Grimley, Gerry Dolan, Charlotte, Stokley, Simone, Astwood, Emma, Longmuir, Karyn, Chang, Cherry, Foros, Merri, Kightley, Michelle, Trower, Linda, Thachil, Jecko, Bolton Maggs, Paula, Hay, Charlie, Pike, Gill, Will, Andrew, Grainger, John, Foulkes, Matt, Fareh, Mona, Talks, Kate, Biss, Tina, Kesteven, Patrick, Hanley, John, Vowles, Julie, Basey, Lesley, Knaggs, Kevin, Barnes, Michelle, Collins, Peter, Rayment, Rachel, Alikhan, Raza, Rebecca Morris, Ana Guerrero, Mansell, Dianne, Toh, Cheng Hock, Martlew, Vanessa, Murphy, Elaine, Lachmann, Robin, Rose, Peter, Chapman, Oliver, Lokare, Anand, Marshall, Kathryn, Khan, Naseem, Keeling, David, Giangrande, Paul, Austin, Steve, Bevan, David, Alamelu, Jayanthi, Allsup, David, Fletcher, Andrew, Gladstone, Katherine, Fenwick, Jeanette, Woods, Philippa, Camp, Darren, James, Beki, Preston, Suzie, Spencer, Collette, Pike, Alexandra, Thomas, Angela, Myers, Bethan, Evans, Gillian, Davies, Karen, Graham, Charlotte, Foad, Miranda, Smith, Jacqueline, Morgan, Neil

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The value of education and self‐monitoring in the management of warfarin therapy in older patients with unstable control of anticoagulation von Khan, Tayyaba Irfan, Kamali, Farhad, Kesteven, Patrick, Avery, Peter, Wynne, Hilary

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Characterization of multiple platelet activation pathways in patients with bleeding as a high-throughput screening option: use of 96-well Optimul assay von Lordkipanidzé, Marie, Lowe, Gillian C., Kirkby, Nicholas S., Chan, Melissa V., Lundberg, Martina H., Morgan, Neil V., Bem, Danai, Nisar, Shaista P., Leo, Vincenzo C., Jones, Matthew L., Mundell, Stuart J., Daly, Martina E., Mumford, Andrew D., Warner, Timothy D., Watson, Steve P.

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Anticoagulation control and cost of monitoring of older patients on chronic warfarin therapy in three settings in North East England von Abohelaika, Salah, Kamali, Farhad, Avery, Peter, Robinson, Brian, Kesteven, Patrick, Wynne, Hilary

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Superficial Thrombophlebitis followed by Pulmonary Embolism von Kesteven, Patrick, Robinson, Brian

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Serial D-Dimer Measurements Are Useful in Predicting the Recurrence of Venous Thromboembolism after Discontinuation of Anticoagulation von Briz, Montserrat, Marr, Helen, Talks, Kate, Hanley, John, Kesteven, Patrick

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A Randomized Trial Comparing Genotype-Guided Dosing of Warfarin to Standard Dosing: The EU Pharmacogenetics of Anticoagulant Therapy (EU-PACT) Warfarin Study von Pirmohamed, Munir, Burnside, Girvan, Stoddern, Jenni, Prince, Clare, Toh, Cheng Hok, Nicholson, Toby, Kesteven, Patrick, Jorgensen, Andrea, Daly, Ann, Maitland-van der Zee, Anke-Hilse, Williamson, Paula, Eriksson, Niclas, Avery, Peter, Kamali, Farhad, Wadelius, Mia

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Platelet Function following Acute Cerebral Ischemia von Smout, Jonathan, Dyker, Alexander, Cleanthis, Marcus, Ford, Gary, Kesteven, Patrick, Stansby, Gererd

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Use of surgical embolectomy von Peng, Ed W K, Simpson, John, Thirugnanasothy, Logan, Kesteven, Patrick, Dark, John H

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Surgical embolectomy is underused von Peng, Ed W K, Simpson, John, Thirugnanasothy, Logan, Kesteven, Patrick, Dark, John H

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