PLOZASIRAN (ARO-APOC3), AN INVESTIGATIONAL RNAI, DEMONSTRATES DEEP AND DURABLE TG REDUCTIONS IN PATIENTS WITH SHTG, SHASTA-2 FINAL RESULTS von Kertesz, Nathalie

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Advances and limitations for the treatment of spinal muscular atrophy von Day, John W, Howell, Kelly, Place, Amy, Long, Kimberly, Rossello, Jose, Kertesz, Nathalie, Nomikos, George

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Blockade of XBP1 splicing by inhibition of IRE1α is a promising therapeutic option in multiple myeloma von Mimura, Naoya, Fulciniti, Mariateresa, Gorgun, Gullu, Tai, Yu-Tzu, Cirstea, Diana, Santo, Loredana, Hu, Yiguo, Fabre, Claire, Minami, Jiro, Ohguchi, Hiroto, Kiziltepe, Tanyel, Ikeda, Hiroshi, Kawano, Yutaka, French, Maureen, Blumenthal, Martina, Tam, Victor, Kertesz, Nathalie L., Malyankar, Uriel M., Hokenson, Mark, Pham, Tuan, Zeng, Qingping, Patterson, John B., Richardson, Paul G., Munshi, Nikhil C., Anderson, Kenneth C.

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A Critical Role of Erythropoietin Receptor in Neurogenesis and Post-Stroke Recovery von Tsai, Peter T, Ohab, John J, Kertesz, Nathalie, Groszer, Matthias, Matter, Cheryl, Gao, Jing, Liu, Xin, Wu, Hong, Carmichael, S. Thomas

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The role of erythropoietin in regulating angiogenesis von Kertesz, Nathalie, Wu, Jun, Chen, Tim H.-P., Sucov, Henry M., Wu, Hong

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The soluble extracellular domain of EphB4 (sEphB4) antagonizes EphB4-EphrinB2 interaction, modulates angiogenesis, and inhibits tumor growth von Kertesz, Nathalie, Krasnoperov, Valery, Reddy, Ramachandra, Leshanski, Lucy, Kumar, S. Ram, Zozulya, Sergey, Gill, Parkash S.

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Genetic background controls tumor development in PTEN-deficient mice von Freeman, Dan, Lesche, Ralf, Kertesz, Nathalie, Wang, Shungyou, Li, Gang, Gao, Jing, Groszer, Matthias, Martinez-Diaz, Hilda, Rozengurt, Nora, Thomas, George, Liu, Xin, Wu, Hong

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Treatment Effects Among Patients with Type 2 and Type 3 SMA Directly Reported by Patients and Caregivers from the TOPAZ Clinical Trial (P2-8.010) von Pokrzywinski, Robin, Cutts, Katelyn, Shah, Hemal, Kertesz, Nathalie, Lesh, Sabrina, Sadanowicz, Mara, Song, Guochen, O’Neil, Janet, Barrett, Doreen, Barnobi, Erin, Baver, Scott

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Erythropoietin (Epo) and EpoR expression and 2 waves of erythropoiesis von Lee, Robert, Kertesz, Nathalie, Joseph, Sean B., Jegalian, Armin, Wu, Hong

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Apitegromab in Spinal Muscular Atrophy (SMA): An Analysis of Multiple Efficacy Endpoints in the TOPAZ Trial (P15-5.005) von Crawford, Thomas, Darras, Basil, Day, John, Song, Guochen, Nomikos, George, Place, Amy, Barrett, Doreen, Bilic, Sanela, O‘Neil, Janet, Kertesz, Nathalie, Cote, Shaun, Patel, Jagdish, Chyung, Yung

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Safety and Efficacy of Apitegromab in Patients With Spinal Muscular Atrophy Types 2 and 3: The Phase 2 TOPAZ Study von Crawford, Thomas O, Darras, Basil T, Day, John W, Dunaway Young, Sally, Duong, Tina, Nelson, Leslie L, Barrett, Doreen, Song, Guochen, Bilic, Sanela, Cote, Shaun, Sadanowicz, Mara, Iarrobino, Ryan, Xu, Tiina J, O'Neil, Janet, Rossello, José, Place, Amy, Kertesz, Nathalie, Nomikos, George, Chyung, Yung

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Safety and Efficacy of Apitegromab in Patients With Spinal Muscular Atrophy Types 2 and 3: The Phase 2 TOPAZ Study

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Relationship of pharmacokinetics and pharmacodynamics to apitegromab efficacy in patients with later-onset spinal muscular atrophy (Types 2 and 3 SMA): Results from the TOPAZ study von Crawford, Thomas, Place, Amy, Barrett, Doreen, Cote, Shaun, Nomikos, George, Song, Guochen, Bilic, Sanela, Kalra, Ashish, Sadanowicz, Mara, O'Neil, Janet, Iarrobino, Ryan, Kertesz, Nathalie, Chyung, Yung

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PTEN tumor suppressor regulates p53 protein levels and activity through phosphatase-dependent and -independent mechanisms von Freeman, Daniel J., Li, Andrew G., Wei, Gang, Li, Heng-Hong, Kertesz, Nathalie, Lesche, Ralf, Whale, Andrew D., Martinez-Diaz, Hilda, Rozengurt, Nora, Cardiff, Robert D., Liu, Xuan, Wu, Hong

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Small Molecule Inhibitor of ITK Disrupts TCR Signaling and Demonstrates Anti-Tumor Efficacy von Faris, Mary, Malyankar, Uriel M, Zeng, Qingping, Flynn, Gary A, Feuer, Gerold, Kertesz, Nathalie L, Vuga, Danka, Lee, Sandra, Rosario, Darlene, Bot, Adrian

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Blockade of XBP1 splicing by inhibition of IRE la is a promising therapeutic option in multiple myeloma von MIMURA, Naoya, FULCINITI, Mariateresa, KIZILTEPE, Tanyel, IKEDA, Hiroshi, KAWANO, Yutaka, FRENCH, Maureen, BLUMENTHAL, Martina, TAM, Victor, KERTESZ, Nathalie L, MALYANKAR, Uriel M, HOKENSON, Mark, PHAM, Tuan, GORGUN, Gullu, QINGPING ZENG, PATTERSON, John B, RICHARDSON, Paul G, MUNSHI, Nikhil C, ANDERSON, Kenneth C, TAI, Yu-Tzu, CIRSTEA, Diana, SANTO, Loredana, YIGUO HU, FABRE, Claire, MINAMI, Jiro, OHGUCHI, Hiroto

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Blockade of XBP1 Splicing by Inhibition of IRE1α Is a Promising Therapeutic Option in Multiple Myeloma von Mimura, Naoya, Fulciniti, Mariateresa, Gorgun, Gullu, Tai, Yu-Tzu, Cirstea, Diana D., Santo, Loredana, Hu, Yiguo, Fabre, Claire, Minami, Jiro, Ohguchi, Hiroto, Kiziltepe, Tanyel, Ikeda, Hiroshi, Kawano, Yutaka, Blumenthal, Martina, Tam, Victor, Kertesz, Nathalie L., Hokenson, Mark, Zeng, Qingping, Patterson, John B., Richardson, Paul G., Munshi, Nikhil C., Anderson, Kenneth C.

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Targeting IRE1α-XBP1 Pathway Is a Novel Therapeutic Strategy In Multiple Myeloma von Mimura, Naoya, Hideshima, Teru, Gorgun, Gullu, Cirstea, Diana, Santo, Loredana, Hu, Yiguo, Fabre, Claire, Blumenthal, Martina, Tam, Victor, Kertesz, Nathalie L., Zeng, Qingping, Patterson, John B., Munshi, Nikhil C., Richardson, Paul, Anderson, Kenneth C.

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USE OF MYOSTATIN INHIBITOR FOR TREATING SPINAL MUSCULAR ATROPHY von NOMIKOS, George, SONG, Guochen, KERTESZ, Nathalie, WEBSTER, Micah T, CHYUNG, Yung

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USE OF MYOSTATIN INHIBITOR FOR TREATING SPINAL MUSCULAR ATROPHY von NOMIKOS, George, SONG, Guochen, KERTESZ, Nathalie, WEBSTER, Micah T, CHYUNG, Yung

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