Cancer-associated fibroblasts suppress SOX2-induced dysplasia in a lung squamous cancer coculture von Chen, Shuang, Giannakou, Andreas, Wyman, Sarah, Gruzas, Janet, Golas, Jonathon, Zhong, Wenyan, Loreth, Christine, Sridharan, Latha, Yamin, Ting-Ting, Damelin, Marc, Geles, Kenneth G.

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Intra-Tumoral Activation of Endosomal TLR Pathways Reveals a Distinct Role for TLR3 Agonist Dependent Type-1 Interferons in Shaping the Tumor Immune Microenvironment von Thomas, Graham, Micci, Luca, Yang, Wenjing, Katakowski, Joseph, Oderup, Cecilia, Sundar, Purnima, Wang, Xiao, Geles, Kenneth G., Potluri, Shobha, Salek-Ardakani, Shahram

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Maintenance of spermatogenesis requires TAF4b, a gonad-specific subunit of TFIID von Falender, Allison E, Freiman, Richard N, Geles, Kenneth G, Lo, Kirk C, Hwang, KeumSil, Lamb, Dolores J, Morris, Patricia L, Tjian, Robert, Richards, JoAnne S

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Tumour-initiating cells: challenges and opportunities for anticancer drug discovery von Zhou, Bin-Bing S, Grindley, Justin C, Zhang, Haiying, Damelin, Marc, Geles, Kenneth G, Dirks, Peter B

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NOTCH3-targeted antibody drug conjugates regress tumors by inducing apoptosis in receptor cells and through transendocytosis into ligand cells von Geles, Kenneth G., Gao, Yijie, Giannakou, Andreas, Sridharan, Latha, Yamin, Ting-Ting, Zhang, Jing, Karim, Riyez, Bard, Joel, Piche-Nicholas, Nicole, Charati, Manoj, Maderna, Andreas, Lucas, Judy, Golas, Jonathon, Guffroy, Magali, Pirie-Shepherd, Steven, Roy, Marc, Qian, Jessie, Franks, Tania, Zhong, Wenyan, O’Donnell, Christopher J., Tchistiakova, Lioudmila, Gerber, Hans-Peter, Sapra, Puja

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Upregulation of RNA Processing Factors in Poorly Differentiated Lung Cancer Cells von Geles, Kenneth G, Zhong, Wenyan, O’Brien, Siobhan K, Baxter, Michelle, Loreth, Christine, Pallares, Diego, Damelin, Marc

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Multidimensional Coculture System to Model Lung Squamous Carcinoma Progression von Chen, Shuang, Giannakou, Andreas, Golas, Jonathon, Geles, Kenneth G.

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Codependent Activators Direct Myoblast-Specific MyoD Transcription von Hu, Ping, Geles, Kenneth G., Paik, Ji-Hye, DePinho, Ronald A., Tjian, Robert

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Reciprocal regulation of amino acid import and epigenetic state through Lat1 and EZH2 von Dann, Stephen G, Ryskin, Michael, Barsotti, Anthony M, Golas, Jonathon, Shi, Celine, Miranda, Miriam, Hosselet, Christine, Lemon, Luanna, Lucas, Judy, Karnoub, Maha, Wang, Fang, Myers, Jeremy S, Garza, Scott J, Follettie, Maximillian T, Geles, Kenneth G, Klippel, Anke, Rollins, Robert A, Fantin, Valeria R

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Cell-Type-Selective Induction of C-Jun by TAF4b Directs Ovarian-Specific Transcription Networks von Geles, Kenneth G., Freiman, Richard N., Liu, Wei-Li, Zheng, Shuang, Voronina, Ekaterina, Tjian, Robert

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Long-term tumor regression induced by an antibody-drug conjugate that targets 5T4, an oncofetal antigen expressed on tumor-initiating cells von Sapra, Puja, Damelin, Marc, Dijoseph, John, Marquette, Kimberly, Geles, Kenneth G, Golas, Jonathon, Dougher, Maureen, Narayanan, Bitha, Giannakou, Andreas, Khandke, Kiran, Dushin, Russell, Ernstoff, Elana, Lucas, Judy, Leal, Mauricio, Hu, George, O'Donnell, Christopher J, Tchistiakova, Lioudmila, Abraham, Robert T, Gerber, Hans-Peter

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Delineation of a Cellular Hierarchy in Lung Cancer Reveals an Oncofetal Antigen Expressed on Tumor-Initiating Cells von DAMELIN, Marc, GELES, Kenneth G, BEHRENS, Carmen, CHOE, Sung E, RIOS, Carol, GRUZAS, Janet, SRIDHARAN, Latha, DOUGHER, Maureen, KUNZ, Arthur, HAMANN, Philip R, EVANS, Deborah, ARMELLINO, Douglas, FOLLETTIE, Maximillian T, KHANDKE, Kiran, MARQUETTE, Kimberly, TCHISTIAKOVA, Lioudmila, BOGHAERT, Erwin R, ABRAHAM, Robert T, WISTUBA, Ignacio I, ZHOU, Bin-Bing S, PING YUAN, BAXTER, Michelle, GOLAS, Jonathon, DIJOSEPH, John F, KARNOUB, Maha, SHUGUANG HUANG, DIESL, Veronica

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Structural Changes in TAF4b-TFIID Correlate with Promoter Selectivity von Liu, Wei-Li, Coleman, Robert A., Grob, Patricia, King, David S., Florens, Laurence, Washburn, Michael P., Geles, Kenneth G., Yang, Joyce L., Ramey, Vincent, Nogales, Eva, Tjian, Robert

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Germline and developmental roles of the nuclear transport factor importin α3 in C. elegans von Geles, Kenneth G., Adam, Stephen A.

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A role for Caenorhabditis elegans importin IMA-2 in germ line and embryonic mitosis von Geles, Kenneth G, Johnson, Jeffrey J, Jong, Sena, Adam, Stephen A

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Multidimensional Coculture System to Model Lung Squamous Carcinoma Progression von Chen, Shuang, Giannakou, Andreas, Golas, Jonathon, Geles, Kenneth G.

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Abstract 4905: Novel gene expression profiles of poorly differentiated lung cancer are enriched in stem cell factors and predictive of worse clinical outcome von Damelin, Marc Isaac, Zhong, Wenyan, Diesl, Veronica K., Follettie, Maximillian T., Geles, Kenneth G.

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Abstract 1697: Therapeutic targeting the NOTCH3 receptor with antibody drug conjugates von Geles, Kenneth G., Gao, Yijie, Sridharan, Latha, Giannakou, Andreas, Yamin, Ting-Ting, Golas, Jonathan, Lucas, Judy, Charati, Manoj, Li, Xiantang, Guffroy, Magali, Nichols, Tim, Wang, Kai, Follettie, Max, Maderna, Andreas, Tchistiakova, Lioudmila, Gerber, Hans-Peter, Sapra, Puja

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Reciprocal regulation of amino acid import and epigenetic state through Lat1 and EZH 2 von Dann, Stephen G, Ryskin, Michael, Barsotti, Anthony M, Golas, Jonathon, Shi, Celine, Miranda, Miriam, Hosselet, Christine, Lemon, Luanna, Lucas, Judy, Karnoub, Maha, Wang, Fang, Myers, Jeremy S, Garza, Scott J, Follettie, Maximillian T, Geles, Kenneth G, Klippel, Anke, Rollins, Robert A, Fantin, Valeria R

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Abstract 5471: Notch-antibody drug conjugates have a different mechanism of action than Notch signaling inhibitors and induce tumor regression von Geles, Kenneth G., Gao, Yijie, Sridharan, Latha, Giannakou, Andreas, Yamin, Ting-Ting, Golas, Jonathan, Charati, Manoj, Khandke, Kiran, Lucas, Judy, Maderna, Andreas, O'Donnell, Christopher J., Tchistiakova, Lioudmila, Gerber, Hans-Peter, Sapra, Puja

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