Low-Level Viremia Persists for at Least 7 Years in Patients on Suppressive Antiretroviral Therapy von Palmer, Sarah, Maldarelli, Frank, Wiegand, Ann, Bernstein, Barry, Hanna, George J., Brun, Scott C., Kempf, Dale J., Mellors, John W., Coffin, John M., King, Martin S.

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Identification of Highly Potent Human Immunodeficiency Virus Type‑1 Protease Inhibitors against Lopinavir and Darunavir Resistant Viruses from Allophenylnorstatine-Based Peptidomim... von Hidaka, Koushi, Kimura, Tooru, Sankaranarayanan, Rajesh, Wang, Jun, McDaniel, Keith F, Kempf, Dale J, Kameoka, Masanori, Adachi, Motoyasu, Kuroki, Ryota, Nguyen, Jeffrey-Tri, Hayashi, Yoshio, Kiso, Yoshiaki

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ART suppresses plasma HIV-1 RNA to a stable set point predicted by pretherapy viremia von Maldarelli, Frank, Palmer, Sarah, King, Martin S, Wiegand, Ann, Polis, Michael A, Mican, JoAnn, Kovacs, Joseph A, Davey, Richard T, Rock-Kress, Diane, Dewar, Robin, Liu, Shuying, Metcalf, Julia A, Rehm, Catherine, Brun, Scott C, Hanna, George J, Kempf, Dale J, Coffin, John M, Mellors, John W

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In vivo kinetics of Wolbachia depletion by ABBV-4083 in L. sigmodontis adult worms and microfilariae von Hübner, Marc P, Koschel, Marianne, Struever, Dominique, Nikolov, Venelin, Frohberger, Stefan J, Ehrens, Alexandra, Fendler, Martina, Johannes, Iliana, von Geldern, Thomas W, Marsh, Kennan, Turner, Joseph D, Taylor, Mark J, Ward, Stephen A, Pfarr, Kenneth, Kempf, Dale J, Hoerauf, Achim

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A Specific Inhibitor of PfCDPK4 Blocks Malaria Transmission: Chemical-genetic Validation von Ojo, Kayode K., Eastman, Richard T., Vidadala, RamaSubbaRao, Zhang, Zhongsheng, Rivas, Kasey L., Choi, Ryan, Lutz, Justin D., Reid, Molly C., Fox, Anna M. W., Hulverson, Matthew A., Kennedy, Mark, Isoherranen, Nina, Kim, Laura M., Comess, Kenneth M., Kempf, Dale J., Verlinde, Christophe L. M. J., Su, Xin-zhuan, Kappe, Stefan H. I., Maly, Dustin J., Fan, Erkang, Van Voorhis, Wesley C.

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Discovery of ABBV-4083, a novel analog of Tylosin A that has potent anti-Wolbachia and anti-filarial activity von von Geldern, Thomas W, Morton, Howard E, Clark, Rick F, Brown, Brian S, Johnston, Kelly L, Ford, Louise, Specht, Sabine, Carr, Robert A, Stolarik, Deanne F, Ma, Junli, Rieser, Matthew J, Struever, Dominique, Frohberger, Stefan J, Koschel, Marianne, Ehrens, Alexandra, Turner, Joseph D, Hübner, Marc P, Hoerauf, Achim, Taylor, Mark J, Ward, Stephen A, Marsh, Kennan, Kempf, Dale J

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Incidence of Resistance in a Double-Blind Study Comparing Lopinavir/Ritonavir Plus Stavudine and Lamivudine to Nelfinavir plus Stavudine and Lamivudine von Kempf, Dale J., King, Martin S., Bernstein, Barry, Cernohous, Paul, Bauer, Eric, Moseley, Jennifer, Gu, Kai, Hsu, Ann, Brun, Scott, Sun, Eugene

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Relative Replication Capacity and Selective Advantage Profiles of Protease Inhibitor-Resistant Hepatitis C Virus (HCV) NS3 Protease Mutants in the HCV Genotype 1b Replicon System von YUPENG HE, KING, Martin S, KEMPF, Dale J, LIANGJUN LU, HOCK BEN LIM, KRISHNAN, Preethi, KATI, Warren, MIDDLETON, Timothy, MOLLA, Akhteruzzaman

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Prevalence, Mutation Patterns, and Effects on Protease Inhibitor Susceptibility of the L76V Mutation in HIV-1 Protease von YOUNG, Thomas P, PARKIN, Neil T, STAWISKI, Eric, PILOT-MATIAS, Tami, TRINH, Roger, KEMPF, Dale J, NORTON, Michael

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Relationship between Adherence and the Development of Resistance in Antiretroviral-Naive, HIV-1—Infected Patients Receiving Lopinavir/Ritonavir or Nelfinavir von King, Martin S., Brun, Scott C., Kempf, Dale J.

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Crystal structure of full‐length Zika virus NS5 protein reveals a conformation similar to Japanese encephalitis virus NS5 von Upadhyay, Anup K., Cyr, Matthew, Longenecker, Kenton, Tripathi, Rakesh, Sun, Chaohong, Kempf, Dale J.

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Pharmacokinetic-Pharmacodynamic Analysis of Lopinavir-Ritonavir in Combination with Efavirenz and Two Nucleoside Reverse Transcriptase Inhibitors in Extensively Pretreated Human Im... von ANN HSU, ISAACSON, Jeffrey, RODE, Richard, KEMPF, Dale J, GRANNEMAN, G. Richard, SUN, Eugene, BRUN, Scott, BERNSTEIN, Barry, LAM, Wayne, BERTZ, Richard, FOIT, Cheryl, RYNKIEWICZ, Karen, RICHARDS, Bruce, KING, Martin

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Selection of Resistance in Protease Inhibitor-Experienced, Human Immunodeficiency Virus Type 1-Infected Subjects Failing Lopinavir- and Ritonavir-Based Therapy: Mutation Patterns a... von HONGMEI MO, KING, Martin S, KING, Kathryn, MOLLA, Akhteruzzaman, BRUN, Scott, KEMPF, Dale J

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Development of an Orally Available and Central Nervous System (CNS) Penetrant Toxoplasma gondii Calcium-Dependent Protein Kinase 1 (TgCDPK1) Inhibitor with Minimal Human Ether-a-go... von Vidadala, Rama Subba Rao, Rivas, Kasey L, Ojo, Kayode K, Hulverson, Matthew A, Zambriski, Jennifer A, Bruzual, Igor, Schultz, Tracey L, Huang, Wenlin, Zhang, Zhongsheng, Scheele, Suzanne, DeRocher, Amy E, Choi, Ryan, Barrett, Lynn K, Siddaramaiah, Latha Kallur, Hol, Wim G. J, Fan, Erkang, Merritt, Ethan A, Parsons, Marilyn, Freiberg, Gail, Marsh, Kennan, Kempf, Dale J, Carruthers, Vern B, Isoherranen, Nina, Doggett, J. Stone, Van Voorhis, Wesley C, Maly, Dustin J

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Ordered accumulation of mutations in HIV protease confers resistance to ritonavir von Molla, Akhteruzzaman, Korneyeva, Marina, Gao, Qing, Vasavanonda, Sudthida, Schipper, Paaline J, Mo, Hong-Mei, Markowitz, Martin, Chernyavskiy, Tatyana, Niu, Ping, Lyons, Nicholas, Hsu, Ann, Granneman, G. Richard, Ho, David D, Boucher, Charles A.B, Leonard, John M, Norbeck, Daniel W, Kempf, Dale J

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Activity of a Potent Hepatitis C Virus Polymerase Inhibitor in the Chimpanzee Model von Chen, Chih-Ming, He, Yupeng, Lu, Liangjun, Lim, Hock Ben, Tripathi, Rakesh L, Middleton, Tim, Hernandez, Lisa E, Beno, David W A, Long, Michelle A, Kati, Warren M, Bosse, Todd D, Larson, Daniel P, Wagner, Rolf, Lanford, Robert E, Kohlbrenner, William E, Kempf, Dale J, Pilot-Matias, Tami J, Molla, Akhteruzzaman

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The Tuberculosis Drug Accelerator at year 10: what have we learned? von Aldridge, Bree B., Barros-Aguirre, David, Barry, Clifton E., Bates, Robert H., Berthel, Steven J., Boshoff, Helena I., Chibale, Kelly, Chu, Xin-Jie, Cooper, Christopher B., Dartois, Véronique, Duncan, Ken, Fotouhi, Nader, Gusovsky, Fabian, Hipskind, Philip A., Kempf, Dale J., Lelièvre, Joël, Lenaerts, Anne J., McNamara, Case W., Mizrahi, Valerie, Nathan, Carl, Olsen, David B., Parish, Tanya, Petrassi, H. Michael, Pym, Alexander, Rhee, Kyu Y., Robertson, Gregory T., Rock, Jeremy Michael, Rubin, Eric J., Russell, Betsy, Russell, David G., Sacchettini, James C., Schnappinger, Dirk, Schrimpf, Michael, Upton, Anna M., Warner, Peter, Wyatt, Paul Graham, Yuan, Ying

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Bumped Kinase Inhibitors as therapy for apicomplexan parasitic diseases: lessons learned von Choi, Ryan, Hulverson, Matthew A., Huang, Wenlin, Vidadala, Rama S.R., Whitman, Grant R., Barrett, Lynn K., Schaefer, Deborah A., Betzer, Dana P., Riggs, Michael W., Doggett, J. Stone, Hemphill, Andrew, Ortega-Mora, Luis Miguel, McCloskey, Molly C., Arnold, Samuel L.M., Hackman, Robert C., Marsh, Kennan C., Lynch, James J., Freiberg, Gail M., Leroy, Bruce E., Kempf, Dale J., Choy, Robert K.M., de Hostos, Eugenio L., Maly, Dustin J., Fan, Erkang, Ojo, Kayode K., Van Voorhis, Wesley C.

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Predictive Genotypic Algorithm for Virologic Response to Lopinavir-Ritonavir in Protease Inhibitor-Experienced Patients von KING, Martin S, RODE, Richard, COHEN-CODAR, Isabelle, CALVEZ, Vincent, MARCELIN, Anne-Geneviève, HANNA, George J, KEMPF, Dale J

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Assembling Pharma Resources to Tackle Diseases of Underserved Populations von Kempf, Dale J., Marsh, Kennan C.

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