Examining crosstalk between CD44 and integrins and its effects on cell migration and traction force in glioblastoma von Kelly, Marcus D.

Volltext

CRISPR screens in cancer spheroids identify 3D growth-specific vulnerabilities von Han, Kyuho, Pierce, Sarah E., Li, Amy, Spees, Kaitlyn, Anderson, Gray R., Seoane, Jose A., Lo, Yuan-Hung, Dubreuil, Michael, Olivas, Micah, Kamber, Roarke A., Wainberg, Michael, Kostyrko, Kaja, Kelly, Marcus R., Yousefi, Maryam, Simpkins, Scott W., Yao, David, Lee, Keonil, Kuo, Calvin J., Jackson, Peter K., Sweet-Cordero, Alejandro, Kundaje, Anshul, Gentles, Andrew J., Curtis, Christina, Winslow, Monte M., Bassik, Michael C.

Volltext

The ciliopathy-associated CPLANE proteins direct basal body recruitment of intraflagellar transport machinery von Toriyama, Michinori, Lee, Chanjae, Taylor, S Paige, Duran, Ivan, Cohn, Daniel H, Bruel, Ange-Line, Tabler, Jacqueline M, Drew, Kevin, Kelly, Marcus R, Kim, Sukyoung, Park, Tae Joo, Braun, Daniela A, Pierquin, Ghislaine, Biver, Armand, Wagner, Kerstin, Malfroot, Anne, Panigrahi, Inusha, Franco, Brunella, Al-lami, Hadeel Adel, Yeung, Yvonne, Choi, Yeon Ja, Duffourd, Yannis, Faivre, Laurence, Rivière, Jean-Baptiste, Chen, Jiang, Liu, Karen J, Marcotte, Edward M, Hildebrandt, Friedhelm, Thauvin-Robinet, Christel, Krakow, Deborah, Jackson, Peter K, Wallingford, John B

Volltext

Bispecific Antibodies and Antibody-Drug Conjugates (ADCs) Bridging HER2 and Prolactin Receptor Improve Efficacy of HER2 ADCs von Andreev, Julian, Thambi, Nithya, Perez Bay, Andres E, Delfino, Frank, Martin, Joel, Kelly, Marcus P, Kirshner, Jessica R, Rafique, Ashique, Kunz, Arthur, Nittoli, Thomas, MacDonald, Douglas, Daly, Christopher, Olson, William, Thurston, Gavin

Volltext

UHRF1 is a mediator of KRAS driven oncogenesis in lung adenocarcinoma von Kostyrko, Kaja, Román, Marta, Lee, Alex G., Simpson, David R., Dinh, Phuong T., Leung, Stanley G., Marini, Kieren D., Kelly, Marcus R., Broyde, Joshua, Califano, Andrea, Jackson, Peter K., Sweet-Cordero, E. Alejandro

Volltext

RAD-TGTs: high-throughput measurement of cellular mechanotype via rupture and delivery of DNA tension probes von Pawlak, Matthew R., Smiley, Adam T., Ramirez, Maria Paz, Kelly, Marcus D., Shamsan, Ghaidan A., Anderson, Sarah M., Smeester, Branden A., Largaespada, David A., Odde, David J., Gordon, Wendy R.

Volltext

Comparative Proteomics Reveals Strain-Specific β-TrCP Degradation via Rotavirus NSP1 Hijacking a Host Cullin-3-Rbx1 Complex von Ding, Siyuan, Mooney, Nancie, Li, Bin, Kelly, Marcus R, Feng, Ningguo, Loktev, Alexander V, Sen, Adrish, Patton, John T, Jackson, Peter K, Greenberg, Harry B

Volltext

Drebrin restricts rotavirus entry by inhibiting dynamin-mediated endocytosis von Li, Bin, Ding, Siyuan, Feng, Ningguo, Mooney, Nancie, Ooi, Yaw Shin, Ren, Lili, Diep, Jonathan, Kelly, Marcus R., Yasukawa, Linda L., Patton, John T., Yamazaki, Hiroyuki, Shirao, Tomoaki, Jackson, Peter K., Greenberg, Harry B.

Volltext

A multi-scale map of cell structure fusing protein images and interactions von Qin, Yue, Huttlin, Edward L., Winsnes, Casper F., Gosztyla, Maya L., Wacheul, Ludivine, Kelly, Marcus R., Blue, Steven M., Zheng, Fan, Chen, Michael, Schaffer, Leah V., Licon, Katherine, Bäckström, Anna, Vaites, Laura Pontano, Lee, John J., Ouyang, Wei, Liu, Sophie N., Zhang, Tian, Silva, Erica, Park, Jisoo, Pitea, Adriana, Kreisberg, Jason F., Gygi, Steven P., Ma, Jianzhu, Harper, J. Wade, Yeo, Gene W., Lafontaine, Denis L. J., Lundberg, Emma, Ideker, Trey

Volltext

Dystrophin missense mutations alter focal adhesion tension and mechanotransduction von Ramirez, Maria Paz, Anderson, Michael J M, Kelly, Marcus D, Sundby, Lauren J, Hagerty, Anthony R, Wenthe, Sophia J, Odde, David J, Ervasti, James M, Gordon, Wendy R

Volltext

A Biparatopic Antibody-Drug Conjugate to Treat MET-Expressing Cancers, Including Those that Are Unresponsive to MET Pathway Blockade von DaSilva, John O., Yang, Katie, Surriga, Oliver, Nittoli, Thomas, Kunz, Arthur, Franklin, Matthew C., Delfino, Frank J., Mao, Shu, Zhao, Feng, Giurleo, Jason T., Kelly, Marcus P., Makonnen, Sosina, Hickey, Carlos, Krueger, Pamela, Foster, Randi, Chen, Zhaoyuan, Retter, Marc W., Slim, Rabih, Young, Tara M., Olson, William C., Thurston, Gavin, Daly, Christopher

Volltext

Combined Proteomic and Genetic Interaction Mapping Reveals New RAS Effector Pathways and Susceptibilities von Kelly, Marcus R., Kostyrko, Kaja, Han, Kyuho, Mooney, Nancie A., Jeng, Edwin E., Spees, Kaitlyn, Dinh, Phuong T., Abbott, Keene L., Gwinn, Dana M., Sweet-Cordero, E. Alejandro, Bassik, Michael C., Jackson, Peter K.

Volltext

Interpretation of cancer mutations using a multiscale map of protein systems von Zheng, Fan, Kelly, Marcus R., Ramms, Dana J., Heintschel, Marissa L., Tao, Kai, Tutuncuoglu, Beril, Lee, John J., Ono, Keiichiro, Foussard, Helene, Chen, Michael, Herrington, Kari A., Silva, Erica, Liu, Sophie N., Chen, Jing, Churas, Christopher, Wilson, Nicholas, Kratz, Anton, Pillich, Rudolf T., Patel, Devin N., Park, Jisoo, Kuenzi, Brent, Yu, Michael K., Licon, Katherine, Pratt, Dexter, Kreisberg, Jason F., Kim, Minkyu, Swaney, Danielle L., Nan, Xiaolin, Fraley, Stephanie, Gutkind, J. Silvio, Krogan, Nevan J., Ideker, Trey

Volltext

Antibody-targeted NY-ESO-1 to mannose receptor or DEC-205 in vitro elicits dual human CD8+ and CD4+ T cell responses with broad antigen specificity von Tsuji, Takemasa, Matsuzaki, Junko, Kelly, Marcus P, Ramakrishna, Venky, Vitale, Laura, He, Li-Zhen, Keler, Tibor, Odunsi, Kunle, Old, Lloyd J, Ritter, Gerd, Gnjatic, Sacha

Volltext

WRN inhibition leads to its chromatin-associated degradation via the PIAS4-RNF4-p97/VCP axis von Rodríguez Pérez, Fernando, Natwick, Dean, Schiff, Lauren, McSwiggen, David, Heckert, Alec, Huey, Melina, Morrison, Huntly, Loo, Mandy, Miranda, Rafael G., Filbin, John, Ortega, Jose, Van Buren, Kayla, Murnock, Danny, Tao, Arnold, Butler, Renee, Cheng, Kylie, Tarvestad, William, Zhang, Zhengjian, Gonzalez, Eric, Miller, Rand M., Kelly, Marcus, Tang, Yangzhong, Ho, Jaclyn, Anderson, Daniel, Bashore, Charlene, Basham, Stephen

Volltext

Mutual antagonism between CD44 and integrins in glioblastoma cell traction and migration von Kelly, Marcus D., Pawlak, Matthew R., Zhan, Kevin H., Shamsan, Ghaidan A., Gordon, Wendy R., Odde, David J.

Volltext

The OTX2 Gene Induces Tumor Growth and Triggers Leptomeningeal Metastasis by Regulating the mTORC2 Signaling Pathway in Group 3 Medulloblastomas von Ampudia-Mesias, Elisabet, Cameron, Charles S, Yoo, Eunjae, Kelly, Marcus, Anderson, Sarah M, Manning, Riley, Abrahante Lloréns, Juan E, Moertel, Christopher L, Yim, Hyungshin, Odde, David J, Saydam, Nurten, Saydam, Okay

Volltext

Antibody drug conjugates of cleavable amino-alkyl and aryl maytansinoids von Nittoli, Thomas, Kelly, Marcus P., Delfino, Frank, Rudge, John, Kunz, Arthur, Markotan, Thomas, Spink, Jan, Chen, Zhaoyuan, Shan, Jing, Navarro, Elizabeth, Tait, Michele, Provoncha, Kathleen, Giurleo, Jason, Zhao, Feng, Jiang, Xiaobo, Hylton, Donna, Makonnen, Sosina, Hickey, Carlos, Kirshner, Jessica R., Thurston, Gavin, Papadopoulos, Nicholas

Volltext

A multi-scale map of protein assemblies in the DNA damage response von Kratz, Anton, Kim, Minkyu, Kelly, Marcus R., Zheng, Fan, Koczor, Christopher A., Li, Jianfeng, Ono, Keiichiro, Qin, Yue, Churas, Christopher, Chen, Jing, Pillich, Rudolf T., Park, Jisoo, Modak, Maya, Collier, Rachel, Licon, Kate, Pratt, Dexter, Sobol, Robert W., Krogan, Nevan J., Ideker, Trey

Volltext

Preclinical Activity of the Novel Anti-Prolactin Receptor (PRLR) Antibody-Drug Conjugate REGN2878-DM1 in PRLR-Positive Breast Cancers von Kelly, Marcus P, Hickey, Carlos, Makonnen, Sosina, Coetzee, Sandra, Jalal, Sumreen, Wang, Yu, Delfino, Frank, Shan, Jing, Potocky, Terra B, Chatterjee, Ishita, Andreev, Julian, Kunz, Arthur, D'Souza, Christopher, Giurleo, Jason T, Nittoli, Thomas, Trail, Pamela A, Thurston, Gavin, Kirshner, Jessica R

Volltext