Discovery of the Clinical Candidate IDOR-1117-2520: A Potent and Selective Antagonist of CCR6 for Autoimmune Diseases von Meyer, Emmanuel A., Croxford, Andrew L., Gnerre, Carmela, Kulig, Paulina, Murphy, Mark J., Jacob, Elise M., Schäfer, Gabriel, Richard-Bildstein, Sylvia, Aissaoui, Hamed, Bouis, Patrick, Ertel, Eric A., de Kanter, Ruben, Keller, Marcel P., Lüthi, Urs, Caroff, Eva

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Discovery of Clinical Candidate ACT-777991, a Potent CXCR3 Antagonist for Antigen-Driven and Inflammatory Pathologies von Meyer, Emmanuel A., Äänismaa, Päivi, Ertel, Eric A., Hühn, Eva, Strasser, Daniel S., Rey, Markus, Murphy, Mark J., Martinic, Marianne M., Pouzol, Laetitia, Froidevaux, Sylvie, Keller, Marcel P., Caroff, Eva

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In Vitro Characterization of Sphingosine 1-Phosphate Receptor 1 (S1P1) Expression and Mediated Migration of Primary Human T and B Cells in the Context of Cenerimod, a Novel, Select... von Schlicher, Lisa, Kulig, Paulina, von Münchow, Audrey, Murphy, Mark J., Keller, Marcel P.

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Immunoaffinity Targeted Mass Spectrometry Analysis of Human Plasma Samples Reveals an Imbalance of Active and Inactive CXCL10 in Primary Sjögren's Syndrome Disease Patients von Schmidt, Alexander, Farine, Hervé, Keller, Marcel P, Sebastian, Agata, Kozera, Lukasz, Welford, Richard W D, Strasser, Daniel S

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Autoimmune Polyendocrine Syndrome Type 1 and NALP5, a Parathyroid Autoantigen von Alimohammadi, Mohammad, Björklund, Peyman, Hallgren, Åsa, Pöntynen, Nora, Szinnai, Gabor, Shikama, Noriko, Keller, Marcel P, Ekwall, Olov, Kinkel, Sarah A, Husebye, Eystein S, Gustafsson, Jan, Rorsman, Fredrik, Peltonen, Leena, Betterle, Corrado, Perheentupa, Jaakko, Åkerström, Göran, Westin, Gunnar, Scott, Hamish S, Holländer, Georg A, Kämpe, Olle

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Keratinocyte growth factor (KGF) enhances postnatal T-cell development via enhancements in proliferation and function of thymic epithelial cells von Rossi, Simona W., Jeker, Lukas T., Ueno, Tomoo, Kuse, Sachiyo, Keller, Marcel P., Zuklys, Saulius, Gudkov, Andrei V., Takahama, Yousuke, Krenger, Werner, Blazar, Bruce R., Holländer, Georg A.

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Preclinical to clinical translation of cenerimod, a novel S1P 1 receptor modulator, in systemic lupus erythematosus von Strasser, Daniel S, Froidevaux, Sylvie, Sippel, Virginie, Gerossier, Estelle, Grieder, Ursula, Pierlot, Gabin M, Kieninger-Graefitsch, Andrea, Vezzali, Enrico, Stalder, Anna K, Renault, Bérengère, Ryge, Jesper, Hart, Aaron, Mentzel, Ulrich, Groenen, Peter M A, Keller, Marcel P, Trendelenburg, Marten, Martinic, Marianne M, Murphy, Mark J

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Donor T-cell alloreactivity against host thymic epithelium limits T-cell development after bone marrow transplantation von Hauri-Hohl, Mathias M., Keller, Marcel P., Gill, Jason, Hafen, Katrin, Pachlatko, Esther, Boulay, Thomas, Peter, Annick, Holländer, Georg A., Krenger, Werner

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Stabilized beta-catenin in thymic epithelial cells blocks thymus development and function von Zuklys, Saulius, Gill, Jason, Keller, Marcel P, Hauri-Hohl, Mathias, Zhanybekova, Saule, Balciunaite, Gina, Na, Kyung-Jae, Jeker, Lukas T, Hafen, Katrin, Tsukamoto, Noriyuki, Amagai, Takashi, Taketo, Makoto M, Krenger, Werner, Holländer, Georg A

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A subpopulation of CD103posICOSpos Treg cells occurs at high frequency in lymphopenic mice and represents a lymph node specific differentiation stage von Barthlott, Thomas, Bosch, Angela J. T., Berkemeier, Caroline, Nogales‐Cadenas, Rubén, Jeker, Lukas T., Keller, Marcel P., Pascual‐Montano, Alberto, Holländer, Georg A.

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TGF-β signaling in thymic epithelial cells regulates thymic involution and postirradiation reconstitution von Hauri-Hohl, Mathias M., Zuklys, Saulius, Keller, Marcel P., Jeker, Lukas T., Barthlott, Thomas, Moon, Anne M., Roes, Jürgen, Holländer, Georg A.

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Preclinical to clinical translation of cenerimod, a novel S1P1 receptor modulator, in systemic lupus erythematosus von Strasser, Daniel S, Froidevaux, Sylvie, Sippel, Virginie, Gerossier, Estelle, Grieder, Ursula, Pierlot, Gabin M, Kieninger-Graefitsch, Andrea, Vezzali, Enrico, Stalder, Anna K, Renault, Bérengère, Ryge, Jesper, Hart, Aaron, Mentzel, Ulrich, Groenen, Peter M A, Keller, Marcel P, Trendelenburg, Marten, Martinic, Marianne M, Murphy, Mark J

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Maintenance of a normal thymic microenvironment and T-cell homeostasis require Smad4-mediated signaling in thymic epithelial cells von Jeker, Lukas T., Barthlott, Thomas, Keller, Marcel P., Zuklys, Saulius, Hauri-Hohl, Mathias, Deng, Chu-Xia, Holländer, Georg A.

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Wnt glycoproteins regulate the expression of FoxN1, the gene defective in nude mice von Holländer, Georg A, Balciunaite, Gina, Keller, Marcel P, Balciunaite, Egle, Piali, Luca, Zuklys, Saulius, Mathieu, Yves D, Gill, Jason, Boyd, Richard, Sussman, Daniel J

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A short primer on early molecular and cellular events in thymus organogenesis and replacement von Barthlott, Thomas, Keller, Marcel P, Krenger, Werner, Holländer, Georg A

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A short primer on early molecular and cellular events in thymus organogenesis and replacement von Barthlott, Thomas, Keller, Marcel P, Krenger, Werner, Holländer, Georg A

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In Vitro Characterization of Sphingosine 1-Phosphate Receptor 1 (S1P 1 ) Expression and Mediated Migration of Primary Human T and B Cells in the Context of Cenerimod, a Novel, Sele... von Schlicher, Lisa, Kulig, Paulina, von Münchow, Audrey, Murphy, Mark J, Keller, Marcel P

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Inherited Neuropathies: From Gene to Disease von Keller, Marcel P., Chance, Phillip F.

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A subpopulation of CD103 super(pos)ICOS super(pos) Treg cells occurs at high frequency in lymphopenic mice and represents a lymph node specific differentiation stage von Barthlott, Thomas, Bosch, Angela JT, Berkemeier, Caroline, Nogales-Cadenas, Ruben, Jeker, Lukas T, Keller, Marcel P, Pascual-Montano, Alberto, Hollaender, Georg A

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A subpopulation of CD103 pos ICOS pos Treg cells occurs at high frequency in lymphopenic mice and represents a lymph node specific differentiation stage von Barthlott, Thomas, Bosch, Angela J. T., Berkemeier, Caroline, Nogales‐Cadenas, Rubén, Jeker, Lukas T., Keller, Marcel P., Pascual‐Montano, Alberto, Holländer, Georg A.

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