High-throughput sequencing of mGluR signaling pathway genes reveals enrichment of rare variants in autism von Kelleher, 3rd, Raymond J, Geigenmüller, Ute, Hovhannisyan, Hayk, Trautman, Edwin, Pinard, Robert, Rathmell, Barbara, Carpenter, Randall, Margulies, David

Volltext

presenilin hypothesis of Alzheimer's disease: Evidence for a loss-of-function pathogenic mechanism von Shen, Jie, Kelleher, Raymond J. III

Volltext

Loss of leucine-rich repeat kinase 2 causes impairment of protein degradation pathways, accumulation of α-synuclein, and apoptotic cell death in aged mice von Tong, Youren, Yamaguchi, Hiroo, Giaime, Emilie, Boyle, Scott, Kopan, Raphael, Kelleher, Raymond J. III, Shen, Jie

Volltext

Developing a Gene Therapy for the Treatment of Autosomal Dominant Alzheimer's Disease von Moore, Benjamin, Sharma, Apurwa, Goulet, Martin, Suter, Tracey, Pelletier, Carolyn, Hu, Ruoxi, Schaeffer, Eric, Kelleher, 3rd, Raymond J

Volltext

Tsx produces a long noncoding RNA and has general functions in the germline, stem cells, and brain von Anguera, Montserrat C, Ma, Weiyuan, Clift, Danielle, Namekawa, Satoshi, Kelleher, 3rd, Raymond J, Lee, Jeannie T

Volltext

Indirect Regulation of Presenilins in CREB-mediated Transcription von Watanabe, Hirotaka, Smith, Miriam J., Heilig, Elizabeth, Beglopoulos, Vassilios, Kelleher, Raymond J., Shen, Jie

Volltext

Loss of Presenilin Function Causes Impairments of Memory and Synaptic Plasticity Followed by Age-Dependent Neurodegeneration von Saura, Carlos A, Choi, Se-Young, Beglopoulos, Vassilios, Malkani, Seema, Zhang, Dawei, Rao, B.S.Shankaranarayana, Chattarji, Sumantra, Kelleher, Raymond J, Kandel, Eric R, Duff, Karen, Kirkwood, Alfredo, Shen, Jie

Volltext

Discovery of NVP-LEQ506, a Second-Generation Inhibitor of Smoothened von Peukert, Stefan, He, Feng, Dai, Miao, Zhang, Rui, Sun, Yingchuan, Miller-Moslin, Karen, McEwan, Michael, Lagu, Bharat, Wang, Kate, Yusuff, Naeem, Bourret, Aaron, Ramamurthy, Arun, Maniara, Wieslawa, Amaral, Adam, Vattay, Anthony, Wang, Anlai, Guo, Ribo, Yuan, Jing, Green, John, Williams, Juliet, Buonamici, Silvia, Kelleher III, Joseph F., Dorsch, Marion

Volltext

Tsx Produces a Long Noncoding RNA and Has General Functions in the Germline, Stem Cells, and Brain: e1002248 von Anguera, Montserrat C, Ma, Weiyuan, Clift, Danielle, Namekawa, Satoshi, Kelleher III, Raymond J, Lee, Jeannie T

Volltext

A Presenilin-1 Mutation Identified in Familial Alzheimer Disease with Cotton Wool Plaques Causes a Nearly Complete Loss of γ-Secretase Activity von Heilig, Elizabeth A., Xia, Weiming, Shen, Jie, Kelleher, Raymond J.

Volltext

Cover Picture: Discovery of NVP-LEQ506, a Second-Generation Inhibitor of Smoothened (ChemMedChem 8/2013) von Peukert, Stefan, He, Feng, Dai, Miao, Zhang, Rui, Sun, Yingchuan, Miller-Moslin, Karen, McEwan, Michael, Lagu, Bharat, Wang, Kate, Yusuff, Naeem, Bourret, Aaron, Ramamurthy, Arun, Maniara, Wieslawa, Amaral, Adam, Vattay, Anthony, Wang, Anlai, Guo, Ribo, Yuan, Jing, Green, John, Williams, Juliet, Buonamici, Silvia, Kelleher III, Joseph F., Dorsch, Marion

Volltext

Effects of activation-defective TBP mutations on transcription initiation in yeast von Kim, T.K, Hashimoto, S, Kelleher, R.J. III, Flanagan, P.M, Kornberg, R.D, Horikoshi, M, Roeder, R.G

Volltext

GENE THERAPY FOR ALZHEIMER'S DISEASE von SHEN, Jie, KELLEHER III, Raymond J

Volltext bestellen

GENE THERAPY FOR ALZHEIMER`S DISEASE von KELLEHER, III, Raymond J, SHEN, Jie

Volltext bestellen

GENE THERAPY FOR ALZHEIMER'S DISEASE von SHEN, Jie, KELLEHER III, Raymond J

Volltext bestellen

GENE THERAPY FOR ALZHEIMER'S DISEASE von SHEN, Jie, KELLEHER III, Raymond J

Volltext bestellen

Gene therapy for alzheimer's disease von SHEN, Jie, KELLEHER III, Raymond J

Volltext bestellen

GENE THERAPY FOR ALZHEIMER`S DISEASE von Shen, Jie, Kelleher, III, Raymond J

Volltext bestellen

GENE THERAPY FOR ALZHEIMER'S DISEASE von SHEN, Jie, KELLEHER III, Raymond J

Volltext bestellen

GENE THERAPY FOR ALZHEIMER'S DISEASE von SHEN, Jie, KELLEHER III, Raymond J

Volltext bestellen