ICH E14-Compatible Holter Bin Method and its Equivalence to Individual Heart Rate Correction in the Assessment of Drug-Induced QT Changes von MALIK, MAREK, HNATKOVA, KATERINA, KOWALSKI, DONNA, KEIRNS, JAMES J., GELDEREN, E. MARCEL VAN

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The Pharmacokinetics and Pharmacodynamics of Micafungin in Experimental Hematogenous Candida Meningoencephalitis: Implications for Echinocandin Therapy in Neonates von Hope, William W., Mickiene, Diana, Petraitis, Vidmantas, Petraitiene, Ruta, Kelaher, Amy M., Hughes, Joanna E., Cotton, Margaret P., Bacher, John, Keirns, James J., Buell, Donald, Heresi, Gloria, Benjamin, Daniel K., Groll, Andreas H., Drusano, George L., Walsh, Thomas J.

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Assessment of Tacrolimus Absorption From the Human Intestinal Tract: Open-Label, Randomized, 4-Way Crossover Study von Tsunashima, Daisuke, Kawamura, Akio, PhD, Murakami, Manabu, MS, Sawamoto, Taiji, PhD, Undre, Nas, PhD, Brown, Malcolm, MD, Groenewoud, Albert, MD, PhD, Keirns, James J., PhD, Holman, John, MD, PhD, Connor, Alyson, PhD, Wylde, Hannah, PhD, Wilding, Ian, PhD, Ogawara, Ken-ichi, PhD, Sako, Kazuhiro, PhD, Higaki, Kazutaka, PhD, First, Roy, MD

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Pharmacokinetics and Safety of Amenamevir in Healthy Subjects: Analysis of Four Randomized Phase 1 Studies von Kusawake, Tomohiro, Keirns, James J., Kowalski, Donna, den Adel, Martin, Groenendaal-van de Meent, Dorien, Takada, Akitsugu, Ohtsu, Yoshiaki, Katashima, Masataka

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The Influence of Hepatic and Renal Impairment on the Pharmacokinetics of a Treatment for Herpes Zoster, Amenamevir (ASP2151): Phase 1, Open-Label, Single-Dose, Parallel-Group Studi... von Kusawake, Tomohiro, Kowalski, Donna, Takada, Akitsugu, Kato, Kota, Katashima, Masataka, Keirns, James J., Lewand, Michaelene, Lasseter, Kenneth C., Marbury, Thomas C., Preston, Richard A.

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Population Pharmacokinetics of Micafungin in Pediatric Patients and Implications for Antifungal Dosing von HOPE, William W, SEIBEL, Nita L, DRUSANO, George L, WALSH, Thomas J, SCHWARTZ, Cindy L, ARRIETA, Antonio, FLYNN, Patricia, SHAD, Aziza, ALBANO, Edythe, KEIRNS, James J, BUELL, Donald N, GUMBO, Tawanda

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QTc changes after meal intake: Sex differences and correlates von Hnatkova, Katerina, PhD, Kowalski, Donna, MSc, Keirns, James J., PhD, van Gelderen, E. Marcel, PhD, Malik, Marek, PhD, MD

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Reproducibility of QTc interval changes after meal intake von Hnatkova, Katerina, PhD, Kowalski, Donna, MSc, Keirns, James J., PhD, van Gelderen, E. Marcel, PhD, Malik, Marek, PhD, MD

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Importance of subject-specific QT/RR curvatures in the design of individual heart rate corrections of the QT interval von Malik, Marek, PhD, MD, Hnatkova, Katerina, PhD, Kowalski, Donna, MS, Keirns, James J., PhD, van Gelderen, E. Marcel, PhD

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Relationship of QT interval variability to heart rate and RR interval variability von Hnatkova, Katerina, PhD, Kowalski, Donna, MS, Keirns, James J., PhD, van Gelderen, E. Marcel, PhD, Malik, Marek, PhD, MD

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Are QTc interval changes after meal intake a reasonable method to prove assay sensitivity in thorough QT studies? von Hnatkova, Katerina, PhD, Kowalski, Donna, MSc, Keirns, James J., PhD, van Gelderen, E. Marcel, PhD, Malik, Marek, PhD, MD

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QT/RR curvatures in healthy subjects: sex differences and covariates von Malik, Marek, Hnatkova, Katerina, Kowalski, Donna, Keirns, James J, van Gelderen, E Marcel

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Have individual QT/RR curvatures value in QT correction? von Malik, Marek, PhD, MD, Hnatkova, Katerina, PhD, Kowalski, Donna, MS, Keirns, James J., PhD, van Gelderen, E. Marcel, PhD

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The Pharmacokinetics and Safety of Micafungin, a Novel Echinocandin, in Premature Infants von Heresi, Gloria P, Gerstmann, Dale R, Reed, Michael D, van den Anker, John N, Blumer, Jeffrey L, Kovanda, Laura, Keirns, James J, Buell, Donald N, Kearns, Gregory L

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Population pharmacokinetics of micafungin in adult patients von Gumbo, Tawanda, Hiemenz, John, Ma, Lei, Keirns, James J, N. Buell, Donald, Drusano, George L

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Pharmacokinetics of Intravenous Conivaptan in Subjects With Hepatic or Renal Impairment von Roy, Michael J., Erdman, Keith A., Abeyratne, Anura T., Plumb, Lisa C., Lasseter, Kenneth, Riff, Dennis S., Keirns, James J.

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Population pharmacokinetic–pharmacodynamic analysis of vernakalant hydrochloride injection (RSD1235) in atrial fibrillation or atrial flutter von Mao, Zhongping, Wheeler, Jeff J., Townsend, Robert, Gao, Yuying, Kshirsagar, Smita, Keirns, James J.

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Lipid-Based Delivery Systems for Improving the Bioavailability and Lymphatic Transport of a Poorly Water-Soluble LTB4 Inhibitor von Hauss, David J., Fogal, Steven E., Ficorilli, James V., Price, Caswall A., Roy, Tapon, Jayaraj, Andrew A., Keirns, James J.

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Link between rhodopsin and disk membrane cyclic nucleotide phosphodiesterase. Action spectrum and sensitivity to illumination von Keirns, James J, Miki, Naomasa, Bitensky, Mark W, Keirns, Mary

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Regulation of Cyclic Nucleotide Concentrations in Photoreceptors: An ATP-Dependent Stimulation of Cyclic Nucleotide Phosphodiesterase by Light von Miki, Naomasa, Keirns, James J., Marcus, Frederick R., Freeman, Jenny, Bitensky, Mark W.

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