The role of IL-22 in intestinal health and disease von Keir, Mary, Yi, Tangsheng, Lu, Timothy, Ghilardi, Nico

Volltext

PD-1 and its ligands in tolerance and immunity von Keir, Mary E, Butte, Manish J, Freeman, Gordon J, Sharpe, Arlene H

Volltext

Discrepancies between patient-reported outcomes, and endoscopic and histological appearance in UC von Colombel, Jean-Frédéric, Keir, Mary E, Scherl, Alexis, Zhao, Rui, de Hertogh, Gert, Faubion, William A, Lu, Timothy T

Volltext

IL-22 alters gut microbiota composition and function to increase aryl hydrocarbon receptor activity in mice and humans von Mar, Jordan S, Ota, Naruhisa, Pokorzynski, Nick D, Peng, Yutian, Jaochico, Allan, Sangaraju, Dewakar, Skippington, Elizabeth, Lekkerkerker, Annemarie N, Rothenberg, Michael E, Tan, Man-Wah, Yi, Tangsheng, Keir, Mary E

Volltext

Programmed Death-1 Ligand 1 Interacts Specifically with the B7-1 Costimulatory Molecule to Inhibit T Cell Responses von Butte, Manish J., Keir, Mary E., Phamduy, Theresa B., Sharpe, Arlene H., Freeman, Gordon J.

Volltext

Ulcerative colitis is characterized by a plasmablast-skewed humoral response associated with disease activity von Uzzan, Mathieu, Martin, Jerome C., Mesin, Luka, Livanos, Alexandra E., Castro-Dopico, Tomas, Huang, Ruiqi, Petralia, Francesca, Magri, Giuliana, Kumar, Shashi, Zhao, Qing, Rosenstein, Adam K., Tokuyama, Minami, Sharma, Keshav, Ungaro, Ryan, Kosoy, Roman, Jha, Divya, Fischer, Jeremy, Singh, Harpriya, Keir, Mary E., Ramamoorthi, Nandhini, O’Gorman, William E., Cohen, Benjamin L., Rahman, Adeeb, Cossarini, Francesca, Seki, Akihiro, Leyre, Louise, Vaquero, Sonia Tejedor, Gurunathan, Sakteesh, Grasset, Emilie K., Losic, Bojan, Dubinsky, Marla, Greenstein, Alexander J., Gottlieb, Zoe, Legnani, Peter, George, James, Irizar, Haritz, Stojmirovic, Aleksandar, Brodmerkel, Carrie, Kasarkis, Andrew, Sands, Bruce E., Furtado, Glaucia, Lira, Sergio A., Tuong, Zewen K., Ko, Huaibin M., Cerutti, Andrea, Elson, Charles O., Clatworthy, Menna R., Merad, Miriam, Suárez-Fariñas, Mayte, Argmann, Carmen, Hackney, Jason A., Victora, Gabriel D., Randolph, Gwendalyn J., Kenigsberg, Ephraim, Colombel, Jean Frederic, Mehandru, Saurabh

Volltext

PD-1 and its ligands in T-cell immunity von Keir, Mary E, Francisco, Loise M, Sharpe, Arlene H

Volltext

Gut-Selective Integrin-Targeted Therapies for Inflammatory Bowel Disease von Lamb, Christopher A, O'Byrne, Sharon, Keir, Mary E, Butcher, Eugene C

Volltext

Selective autophagy of the adaptor TRIF regulates innate inflammatory signaling von Samie, Mohammad, Lim, Junghyun, Verschueren, Erik, Baughman, Joshua M., Peng, Ivan, Wong, Aaron, Kwon, Youngsu, Senbabaoglu, Yasin, Hackney, Jason A., Keir, Mary, Mckenzie, Brent, Kirkpatrick, Donald S., van Lookeren Campagne, Menno, Murthy, Aditya

Volltext

PD-1 Regulates Self-Reactive CD8+ T Cell Responses to Antigen in Lymph Nodes and Tissues von Keir, Mary E, Freeman, Gordon J, Sharpe, Arlene H

Volltext

Etrolizumab as induction therapy for ulcerative colitis: a randomised, controlled, phase 2 trial von Vermeire, Séverine, Dr, O'Byrne, Sharon, MD, Keir, Mary, PhD, Williams, Marna, PhD, Lu, Timothy T, MD, Mansfield, John C, MD, Lamb, Christopher A, MD, Feagan, Brian G, MD, Panes, Julian, MD, Salas, Azucena, PhD, Baumgart, Daniel C, MD, Schreiber, Stefan, MD, Dotan, Iris, MD, Sandborn, William J, MD, Tew, Gaik W, MSc, Luca, Diana, PhD, Tang, Meina T, PhD, Diehl, Lauri, DVM, Eastham-Anderson, Jeffrey, MS, De Hertogh, Gert, MD, Perrier, Clementine, PhD, Egen, Jackson G, PhD, Kirby, John A, PhD, van Assche, Gert, MD, Rutgeerts, Paul, MD

Volltext

Regulation and Role of αE Integrin and Gut Homing Integrins in Migration and Retention of Intestinal Lymphocytes during Inflammatory Bowel Disease von Keir, Mary E., Fuh, Franklin, Ichikawa, Ryan, Acres, Meghan, Hackney, Jason A., Hulme, Gillian, Carey, Christopher D., Palmer, Jeremy, Jones, Claire J., Long, Anna K., Jiang, Jenny, Klabunde, Sha, Mansfield, John C., Looney, Cary M., Faubion, William A., Filby, Andrew, Kirby, John A., McBride, Jacqueline, Lamb, Christopher A.

Volltext

Association Between Response to Etrolizumab and Expression of Integrin αE and Granzyme A in Colon Biopsies of Patients With Ulcerative Colitis von Tew, Gaik W, Hackney, Jason A, Gibbons, Deena, Lamb, Christopher A, Luca, Diana, Egen, Jackson G, Diehl, Lauri, Eastham Anderson, Jeff, Vermeire, Severine, Mansfield, John C, Feagan, Brian G, Panes, Julian, Baumgart, Daniel C, Schreiber, Stefan, Dotan, Iris, Sandborn, William J, Kirby, John A, Irving, Peter M, De Hertogh, Gert, Van Assche, Gert A, Rutgeerts, Paul, O’Byrne, Sharon, Hayday, Adrian, Keir, Mary E

Volltext

Tissue expression of PD-L1 mediates peripheral T cell tolerance von Keir, Mary E, Liang, Spencer C, Guleria, Indira, Latchman, Yvette E, Qipo, Andi, Albacker, Lee A, Koulmanda, Maria, Freeman, Gordon J, Sayegh, Mohamed H, Sharpe, Arlene H

Volltext

CD28 costimulation regulates genome-wide effects on alternative splicing von Butte, Manish J, Lee, Sun Jung, Jesneck, Jonathan, Keir, Mary E, Haining, W Nicholas, Sharpe, Arlene H

Volltext

The programmed death-1 ligand 1:B7-1 pathway restrains diabetogenic effector T cells in vivo von Paterson, Alison M, Brown, Keturah E, Keir, Mary E, Vanguri, Vijay K, Riella, Leonardo V, Chandraker, Anil, Sayegh, Mohamed H, Blazar, Bruce R, Freeman, Gordon J, Sharpe, Arlene H

Volltext

Gut Microbial Species and Endotypes Associate with Remission in Ulcerative Colitis Patients Treated with Anti-TNF or Anti-integrin Therapy von Tamburini, Fiona B, Tripathi, Anupriya, Gold, Maxwell P, Yang, Julianne C, Biancalani, Tommaso, McBride, Jacqueline M, Keir, Mary E, GARDENIA Study Group

Volltext

Endothelial programmed death-1 ligand 1 (PD-L1) regulates CD8+ T-cell mediated injury in the heart von Grabie, Nir, Gotsman, Israel, DaCosta, Rosa, Pang, Hong, Stavrakis, George, Butte, Manish J, Keir, Mary E, Freeman, Gordon J, Sharpe, Arlene H, Lichtman, Andrew H

Volltext

The B7/CD28 costimulatory family in autoimmunity von Keir, Mary E., Sharpe, Arlene H.

Volltext

PD-L1 has distinct functions in hematopoietic and nonhematopoietic cells in regulating T cell responses during chronic infection in mice von Mueller, Scott N, Vanguri, Vijay K, Ha, Sang-Jun, West, Erin E, Keir, Mary E, Glickman, Jonathan N, Sharpe, Arlene H, Ahmed, Rafi

Volltext