Identification and Validation of an Anthracycline/ Cyclophosphamide-Based Chemotherapy Response Assay in Breast Cancer von MULLIGAN, Jude M, HILL, Laura A, QUINN, Jennifer E, LINDOR, Noralane M, MULLAN, Paul B, JAMES, Colin R, WALKER, Steven M, KERR, Peter, JAMES, Jacqueline, DAVISON, Timothy S, PROUTSKI, Vitali, SALTO-TELLEZ, Manuel, DEHARO, Steve, JOHNSTON, Patrick G, COUCH, Fergus J, HARKIN, D. Paul, KENNEDY, Richard D, IRWIN, Gareth, BOYLE, David, KEATING, Katherine E, RAJI, Olaide Y, MCDYER, Fionnuala A, O'BRIEN, Eamonn, BYLESJO, Max

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Cross-laboratory validation of the OncoScan® FFPE Assay, a multiplex tool for whole genome tumour profiling von Foster, Joseph M, Oumie, Assa, Togneri, Fiona S, Vasques, Fabiana Ramos, Hau, Debra, Taylor, Morag, Tinkler-Hundal, Emma, Southward, Katie, Medlow, Paul, McGreeghan-Crosby, Keith, Halfpenny, Iris, McMullan, Dominic J, Quirke, Phil, Keating, Katherine E, Griffiths, Mike, Spink, Karen G, Brew, Fiona

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ATM associates with and phosphorylates p53: mapping the region of interaction von Khanna, Kum Kum, Keating, Katherine E, Kozlov, Sergei, Scott, Shaun, Gatei, Magtouf, Hobson, Karen, Taya, Yoichi, Gabrielli, Brian, Chan, Doug, Lees-Miller, Susan P, Lavin, Martin F

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Analytical Performance of a 15-Gene Prognostic Assay for Early-Stage Non–Small-Cell Lung Carcinoma Using RNA-Stabilized Tissue von Huang, Shuguang, Reitze, Nicholas J, Ewing, Amy L, McCreary, Suzanne, Uihlein, Arlette H, Brower, Stacey L, Wang, Dakun, Wang, Tianhua, Gabrin, Michael J, Keating, Katherine E, Mulligan, Jude, Wilson, Claire, Davison, Timothy, McKenzie, Stuart, Tsao, Ming-Sound, Shepherd, Frances A, Plamadeala, Victoria

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Transcriptional downregulation of ATM by EGF is defective in ataxia-telangiectasia cells expressing mutant protein von KEATING, Katherine E, GUEVEN, Nuri, WATTERS, Dianne, RODEMANN, H. Peter, LAVIN, Martin F

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Epidermal Growth Factor Sensitizes Cells to Ionizing Radiation by Down-regulating Protein Mutated in Ataxia-Telangiectasia von Gueven, Nuri, Keating, Katherine E., Chen, Philip, Fukao, Toshiyuki, Khanna, Kum Kum, Watters, Dianne, Rodemann, Peter H., Lavin, Martin F.

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Abstract MIP-055: IDENTIFICATION OF A MOLECULAR SUBTYPE OF HIGH GRADE SEROUS OVARIAN CANCER REPRESENTING MAPK PATHWAY ACTIVATION AND PLATINUM RESISTANCE von El-Helali, Aya, McCabe, Nuala, Gourley, Charlie, McCavigan, Andrena, Michie, Caroline O., Price, Bethanie, McGivern, Niamh, Churchman, Michael, El-Helai, Aya, O'Brien, Eamonn J., Hill, Laura, Davison, Timothy S, Williams, Alistair, McCluggage, W Glenn, Keating, Katherine E, Harkin, Denis P, Kennedy, Richard

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Abstract 626: Cross-site reproducibility and orthogonal validation of copy number and somatic mutation calls of OncoScan® FFPE Assay Kit in solid tumors von Foster, Joseph M., Oumie, Assa, Togneri, Fiona S., Taylor, Morag, Alyas, Sofia, Wojtowicz, Paula, Wood, Henry, Tinkler-Hundal, Emma, Southward, Katie, McMullan, Dominic, Quirke, Phil, Keating, Katherine E., Griffiths, Mike, Spink, Karen G., Brew, Fiona, Fung, Eric, Schmidt, Jeanette

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Performance of a prognostic genomic signature for early-stage NSCLC in matched fresh frozen and RNA-stabilized tissue von Huang, Shuguang, Ewing, Amy L, Reitze, Nicholas J, Uihlein, Arlette H, Wang, Dakun, Gabrin, Michael J, Keating, Katherine E., Mulligan, Jude, Wilson, Claire, Davison, Timothy, McKenzie, Stuart, Tsao, Ming-Sound, Shepherd, Frances A., Brower, Stacey L

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Molecular subgroup of high-grade serous ovarian cancer (HGSOC) as a predictor of outcome following bevacizumab von Gourley, Charlie, McCavigan, Andrena, Perren, Timothy, Paul, James, Michie, Caroline Ogilvie, Churchman, Michael, Williams, Alistair, McCluggage, W. Glenn, Parmar, Mahesh, Kaplan, Richard S., Hill, Laura A., Halfpenny, Iris A, O'Brien, Eamonn J., Raji, Olaide, Deharo, Steve, Davison, Timothy, Johnston, Patrick, Keating, Katherine E., Harkin, D. Paul, Kennedy, Richard D.

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Identification and validation of an assay predictive of response and prognosis following anthracycline-based chemotherapy for early breast cancer von Mulligan, Jude M., Hill, Laura A., Deharo, Steve, Keating, Katherine E., Raji, Olaide, McDyer, Fionnuala A., James, Jacqueline, Irwin, Gareth, Boyle, David, Quinn, Jennifer E., Mullan, Paul B., James, Colin R., Salto-Tellez, Manuel, Davison, Timothy S., Johnston, Patrick, Couch, Fergus J., Harkin, D. Paul, Kennedy, Richard D.

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teste de diagnóstico molecular para prever resposta às drogas antiangiogênicas e prognóstico de câncer von SINEAD DONEGAN, TIMOTHY DAVISON, KATHERINE E. KEATING, STEVE DEHARO, GERA JELLEMA, ANDRENA MCCAVIGAN, FIONNUALA PATTERSON, CHARLIE GOURLEY, DENIS PAUL HARKIN, RICHARD KENNEDY, LAURA A. HILL

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teste de diagnóstico molecular para câncer von Richard Kennedy, Laura A. Hill, Vitali Proutski, Max Bylesjo, Katherine E. Keating, Steve Deharo, Fionnuala McDyer, Nicolas Goffard, Paul Denis Harkin, Timothy Davison, Jude O'Donnell

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Detection of a novel common mutation in the ryanodine receptor gene in malignant hyperthermia: implications for diagnosis and heterogeneity studies von Quane, Kathleen A., Keating, Katherine E., Manning, Bernadette M., Healy, J.M.Sandra, Monsleurs, Koen, Heffron, James J.A., Lehane, Mary, Heytens, Luc, Krivosic-Horber, Renee, Adnet, Pascal, Ellis, F.Richard, Monnler, Nicole, Lunardl, Joel, McCarthy, Tommie V.

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Detection of a novel RYR1 mutation in four malignant hyperthermia pedigrees von Keating, Katherine E., Quane, Kathleen A., Manning, Bernadette M., Lehane, Mary, Hartung, Edmund, Censier, Kathrin, Urwyler, Albert, Klausnitzer, Monika, Muller, Clemens R., Heffron, James J.A., McCarthy, Tommie V.

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MOLECULAR DIAGNOSTIC TEST FOR CANCER von BYLESJO, MAX, HARKIN, DENIS, PAUL, DAVISON, TIMOTHY, O'DONNELL, JUDE, DEHARO, STEVE, KENNEDY, RICHARD, KEATING, KATHERINE, E, MCDYER, FIONNUALA, PROUTSKI, VITALI, GOFFARD NICOLAS, HILL, LAURA, A

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MOLECULAR DIAGNOSTIC TEST FOR CANCER von O'DONNELL, Jude, DAVISON, Timothy, HILL, Laura A, HARKIN, Denis Paul, KENNEDY, Richard, KEATING, Katherine E

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Mutation Screening of the RYR1 Gene in Malignant Hyperthermia: Detection of a Novel Tyr to Ser Mutation in a Pedigree with Associated Central Cores von Quane, Kathleen A., Keating, Katherine E., Healy, J.M.Sandra, Manning, Bernadette M., Krivosic-Horber, Renee, Krivosic, I., Monnier, Nicole, Lunardi, Joel, McCarthy, Tommie V.

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Detection of a novel mutation in the ryanodine receptor gene in an Irish malignant hyperthermia pedigree: correlation of the IVCT response with the affected and unaffected haplotyp... von Keating, K E, Giblin, L, Lynch, P J, Quane, K A, Lehane, M, Heffron, J J, McCarthy, T V

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MOLECULAR DIAGNOSTIC TEST FOR CANCER von EAMONN J. O'BRIEN, KATHERINE E. KEATING, MAX BYLESJO, STEVE DEHARO, ANDRENA MCCAVIGAN, DENNIS PAUL HARKIN, CLAIRE TRINDER, VITALI PROUTSKI, TIMOTHY DAVISON, ANDREAS WINTER, FIONNUALA PATTERSON, CAROLINE MICHIE, JUDE O'DONNELL, CHARLIE GOURLEY, RICHARD KENNEDY, LAURA A. HILL

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