Pharmacokinetic and metabolomic studies with a BIO 300 Oral Powder formulation in nonhuman primates von Li, Yaoxiang, Girgis, Michael, Jayatilake, Meth, Serebrenik, Artur A., Cheema, Amrita K., Kaytor, Michael D., Singh, Vijay K.

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Pharmacokinetic and Metabolomic Studies with BIO 300, a Nanosuspension of Genistein, in a Nonhuman Primate Model von Cheema, Amrita K, Mehta, Khyati Y, Santiago, Paola T, Fatanmi, Oluseyi O, Kaytor, Michael D, Singh, Vijay K

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BIO 300 Attenuates Whole Blood Transcriptome Changes in Mice Exposed to Total-Body Radiation von Serebrenik, Artur A, Fatanmi, Oluseyi O, Wise, Stephen Y, Petrus, Sarah A, Kaytor, Michael D, Singh, Vijay K

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Targeted Metabolomics Identifies Pharmacodynamic Biomarkers for BIO 300 Mitigation of Radiation-Induced Lung Injury von Jones, Jace W., Jackson, Isabel L., Vujaskovic, Zeljko, Kaytor, Michael D., Kane, Maureen A.

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Mechanism and therapeutic window of a genistein nanosuspension to protect against hematopoietic-acute radiation syndrome von Landauer, Michael R, Harvey, Adam J, Kaytor, Michael D, Day, Regina M

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Novel Vector Design and Hexosaminidase Variant Enabling Self-Complementary Adeno-Associated Virus for the Treatment of Tay-Sachs Disease von Karumuthil-Melethil, Subha, Nagabhushan Kalburgi, Sahana, Thompson, Patrick, Tropak, Michael, Kaytor, Michael D, Keimel, John G, Mark, Brian L, Mahuran, Don, Walia, Jagdeep S, Gray, Steven J

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Microbiome study in irradiated mice treated with BIO 300, a promising radiation countermeasure von Cheema, Amrita K., Li, Yaoxiang, Singh, Jatinder, Johnson, Ryan, Girgis, Michael, Wise, Stephen Y., Fatanmi, Oluseyi O., Kaytor, Michael D., Singh, Vijay K.

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Serine 776 of Ataxin-1 Is Critical for Polyglutamine-Induced Disease in SCA1 Transgenic Mice von Emamian, Effat S., Kaytor, Michael D., Duvick, Lisa A., Zu, Tao, Tousey, Susan K., Zoghbi, Huda Y., Clark, H.Brent, Orr, Harry T.

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BIO 300, a nanosuspension of genistein, mitigates pneumonitis/fibrosis following high‐dose radiation exposure in the C57L/J murine model von Jackson, Isabel L, Zodda, Andrew, Gurung, Ganga, Pavlovic, Radmila, Kaytor, Michael D, Kuskowski, Michael A, Vujaskovic, Zeljko

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Multicenter Phase 1b/2a Clinical Trial of Radioprotectant BIO 300 Oral Suspension for Patients With Non-Small Cell Lung Cancer Receiving Concurrent Chemoradiotherapy von Simone, 2nd, Charles B, Serebrenik, Artur A, Gore, Elizabeth M, Mohindra, Pranshu, Brown, Stephen L, Wang, Ding, Chetty, Indrin J, Vujaskovic, Zeljko, Menon, Smitha, Thompson, Jonathan, Fine, Gil, Kaytor, Michael D, Movsas, Benjamin

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BIO 300, a Nanosuspension of Genistein, Mitigates Radiation-Induced Erectile Dysfunction and Sensitizes Human Prostate Cancer Xenografts to Radiation Therapy von Jackson, Isabel L., Pavlovic, Rada, Alexander, Allen A., Connors, Caroline Q., Newman, Diana, Mahmood, Javed, Eley, John, Harvey, Adam J., Kaytor, Michael D., Vujaskovic, Zeljko

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Comparative proteomic analysis of serum from nonhuman primates administered BIO 300: a promising radiation countermeasure von Girgis, Michael, Li, Yaoxiang, Ma, Junfeng, Sanda, Miloslav, Wise, Stephen Y., Fatanmi, Oluseyi O., Kaytor, Michael D., Cheema, Amrita K., Singh, Vijay K.

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BIO 300: A Prophylactic Radiation Countermeasure for Acute Radiation Syndrome von Singh, Vijay K, Serebrenik, Artur A, Wise, Stephen Y, Petrus, Sarah A, Fatanmi, Oluseyi O, Kaytor, Michael D

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Six-month partial suppression of Huntingtin is well tolerated in the adult rhesus striatum von GRONDIN, Richard, KAYTOR, Michael D, KAEMMERER, William F, YI AI, NELSON, Peter T, THAKKER, Deepak R, HEISEL, Jennifer, WEATHERSPOON, Marcy R, BLUM, Janelle L, BURRIGHT, Eric N, ZHIMING ZHANG

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Safety, Pharmacokinetics, and Biomarkers of an Amorphous Solid Dispersion of Genistein, a Radioprotectant, in Healthy Volunteers von Serebrenik, Artur A., Verduyn, Carin W., Kaytor, Michael D.

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DNA Nanoparticles: Detection of Long-Term Transgene Activity in Brain using Bioluminescence Imaging von Yurek, David M., Fletcher, Anita M., McShane, Matthew, Kowalczyk, Tomasz H., Padegimas, Linas, Weatherspoon, Marcy R., Kaytor, Michael D., Cooper, Mark J., Ziady, Assem G.

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Recovery from Polyglutamine-Induced Neurodegeneration in Conditional SCA1 Transgenic Mice von Zu, Tao, Duvick, Lisa A, Kaytor, Michael D, Berlinger, Michael S, Zoghbi, Huda Y, Clark, H. Brent, Orr, Harry T

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The GSK3 β signaling cascade and neurodegenerative disease von Kaytor, Michael D, Orr, Harry T

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Modulating huntingtin half‐life alters polyglutamine‐dependent aggregate formation and cell toxicity von Kaytor, Michael D., Wilkinson, Keith D., Warren, Stephen T.

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Interaction of Akt-Phosphorylated Ataxin-1 with 14-3-3 Mediates Neurodegeneration in Spinocerebellar Ataxia Type 1 von Chen, Hung-Kai, Fernandez-Funez, Pedro, Acevedo, Summer F., Lam, Yung C., Kaytor, Michael D., Fernandez, Michael H., Aitken, Alastair, Skoulakis, Efthimios M.C., Orr, Harry T., Botas, Juan, Zoghbi, Huda Y.

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