Efficient 1H NMR chiral discrimination of sulfoxides caused by the dynamic nature of (R,R)-3′,3″-biBINOL von Kawanami, Toshio, Ishizuka, Kentaro, Furuno, Hiroshi, Shiota, Yoshihito, Yoshizawa, Kazunari, Inanaga, Junji

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Discovery and Characterization of Allosteric WNK Kinase Inhibitors von Yamada, Ken, Zhang, Ji-Hu, Xie, Xiaoling, Reinhardt, Juergen, Xie, Amy Qiongshu, LaSala, Daniel, Kohls, Darcy, Yowe, David, Burdick, Debra, Yoshisue, Hajime, Wakai, Hiromichi, Schmidt, Isabel, Gunawan, Jason, Yasoshima, Kayo, Yue, Q. Kimberley, Kato, Mitsunori, Mogi, Muneto, Idamakanti, Neeraja, Kreder, Natasha, Drueckes, Peter, Pandey, Pramod, Kawanami, Toshio, Huang, Waanjeng, Yagi, Yukiko I, Deng, Zhan, Park, Hyi-Man

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Synthesis and reactions of 5-tributylstannyl-4-fluoro-1H-pyrazole von Hanamoto, Takeshi, Suetake, Takao, Koga, Yukinori, Kawanami, Toshio, Furuno, Hiroshi, Inanaga, Junji

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Crystal Structure of a Dewar Benzene Derivative Formed from Fluoro(triisopropylsilyl)acetylene von Hanamoto, Takeshi, Koga, Yukinori, Kawanami, Toshio, Furuno, Hiroshi, Inanaga, Junji

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Paradoxical Increase of Permeability and Lipophilicity with the Increasing Topological Polar Surface Area within a Series of PRMT5 Inhibitors von Argikar, Upendra, Blatter, Markus, Bednarczyk, Dallas, Chen, Zhuoliang, Cho, Young Shin, Doré, Michaël, Dumouchel, Jennifer L., Ho, Samuel, Hoegenauer, Klemens, Kawanami, Toshio, Mathieu, Simon, Meredith, Erik, Möbitz, Henrik, Murphy, Stephen K., Parthasarathy, Saravanan, Soldermann, Carole Pissot, Santos, Jobette, Silver, Serena, Skolnik, Suzanne, Stojanovic, Aleksandar

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Synthesis and crystal structure of 1,2,4-trifluoro-3,5,6-tris(triisopropylsilyl)benzene von Hanamoto, Takeshi, Koga, Yukinori, Kawanami, Toshio, Furuno, Hiroshi, Inanaga, Junji

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Discovery of 4-((2 S ,4 S )-4-Ethoxy-1-((5-methoxy-7-methyl-1 H -indol-4-yl)methyl)piperidin-2-yl)benzoic Acid (LNP023), a Factor B Inhibitor Specifically Designed To Be Applicable... von Mainolfi, Nello, Ehara, Takeru, Karki, Rajeshri G, Anderson, Karen, Mac Sweeney, Aengus, Liao, Sha-Mei, Argikar, Upendra A, Jendza, Keith, Zhang, Chun, Powers, James, Klosowski, Daniel W, Crowley, Maura, Kawanami, Toshio, Ding, Jian, April, Myriam, Forster, Cornelia, Serrano-Wu, Michael, Capparelli, Michael, Ramqaj, Rrezarta, Solovay, Catherine, Cumin, Frederic, Smith, Thomas M, Ferrara, Luciana, Lee, Wendy, Long, Debby, Prentiss, Melissa, De Erkenez, Andrea, Yang, Louis, Liu, Fang, Sellner, Holger, Sirockin, Finton, Valeur, Eric, Erbel, Paulus, Ostermeier, Daniela, Ramage, Paul, Gerhartz, Bernd, Schubart, Anna, Flohr, Stefanie, Gradoux, Nathalie, Feifel, Roland, Vogg, Barbara, Wiesmann, Christian, Maibaum, Jürgen, Eder, Jörg, Sedrani, Richard, Harrison, Richard A, Mogi, Muneto, Jaffee, Bruce D, Adams, Christopher M

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A novel diclofenac-hydrogel conjugate system for intraarticular sustained release: Development of 2-pyridylamino-substituted 1-phenylethanol (PAPE) and its derivatives as tunable t... von Kawanami, Toshio, LaBonte, Laura R., Amin, Jakal, Thibodeaux, Stefan J., Lee, Cameron C., Argintaru, O. Andreea, Adams, Christopher M.

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Optimization of Allosteric With-No-Lysine (WNK) Kinase Inhibitors and Efficacy in Rodent Hypertension Models von Yamada, Ken, Levell, Julian, Yoon, Taeyong, Kohls, Darcy, Yowe, David, Rigel, Dean F, Imase, Hidetomo, Yuan, Jun, Yasoshima, Kayo, DiPetrillo, Keith, Monovich, Lauren, Xu, Lingfei, Zhu, Meicheng, Kato, Mitsunori, Jain, Monish, Idamakanti, Neeraja, Taslimi, Paul, Kawanami, Toshio, Argikar, Upendra A, Kunjathoor, Vidya, Xie, Xiaoling, Yagi, Yukiko I, Iwaki, Yuki, Robinson, Zachary, Park, Hyi-Man

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Discovery of a Novel Piperidine-Based Inhibitor of Cholesteryl Ester Transfer Protein (CETP) That Retains Activity in Hypertriglyceridemic Plasma von Yamada, Ken, Brousseau, Margaret, Honma, Wataru, Iimura, Akiko, Imase, Hidetomo, Iwaki, Yuki, Kawanami, Toshio, LaSala, Daniel, Liang, Guiqing, Mitani, Hironobu, Nonomura, Kazuhiko, Ohmori, Osamu, Pan, Meihui, Rigel, Dean F, Umemura, Ichiro, Yasoshima, Kayo, Zhu, Guoming, Mogi, Muneto

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Efficient preparation of Ellmanas imines from trifluoromethyl ketones promoted by zirconium(IV) tert-butoxide von Kawanami, Toshio, Karns, Alexander, Adams, Christopher, Serrano-Wu, Michael

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Structure based design of nicotinamide phosphoribosyltransferase (NAMPT) inhibitors from a phenotypic screen von Palacios, Daniel S., Meredith, Erik, Kawanami, Toshio, Adams, Christopher, Chen, Xin, Darsigny, Veronique, Geno, Erin, Palermo, Mark, Baird, Daniel, Boynton, Geoffrey, Busby, Scott A., George, Elizabeth L., Guy, Chantale, Hewett, Jeffrey, Tierney, Laryssa, Thigale, Sachin, Weihofen, Wilhelm, Wang, Louis, White, Nicole, Yin, Ming, Argikar, Upendra A.

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Efficient preparation of Ellman’s imines from trifluoromethyl ketones promoted by zirconium(IV) tert-butoxide von Kawanami, Toshio, Karns, Alexander S., Adams, Christopher M., Serrano-Wu, Michael

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Remarkable effect of tris(4-fluorophenyl)phosphine oxide on the stabilization of chiral lanthanum complex catalysts. A new and practical protocol for the highly enantioselective ep... von Kino, Rie, Daikai, Kazuhiro, Kawanami, Toshio, Furuno, Hiroshi, Inanaga, Junji

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Microstructure and Crystal Phase Development of Y2O3-Stabilized ZrO2 Polycrystal Fabricated by the Solid Phase Mixing and Sintering Method von OHNISHI, Hiroshi, FUKUHARA, Tetsurou, KAWANAMI, Toshio, SEKINO, Tohru, IKUHARA, Yuichi, NIIHARA, Koichi

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Scaffold Morphing Identifies 3‑Pyridyl Azetidine Ureas as Inhibitors of Nicotinamide Phosphoribosyltransferase (NAMPT) von Palacios, Daniel S, Meredith, Erik L, Kawanami, Toshio, Adams, Christopher M, Chen, Xin, Darsigny, Veronique, Palermo, Mark, Baird, Daniel, George, Elizabeth L, Guy, Chantale, Hewett, Jeffrey, Tierney, Laryssa, Thigale, Sachin, Wang, Louis, Weihofen, Wilhelm A

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Structure-Guided Design of Substituted Biphenyl Butanoic Acid Derivatives as Neprilysin Inhibitors von Kawanami, Toshio, Karki, Rajeshri G, Cody, Emma, Liu, Qian, Liang, Guiqing, Ksander, Gary M, Rigel, Dean F, Schiering, Nikolaus, Gong, Yongjin, Coppola, Gary M, Iwaki, Yuki, Sun, Robert, Neubert, Alan, Fan, Li, Ingles, Sara, D’Arcy, Allan, Villard, Frederic, Ramage, Paul, Jeng, Arco Y, Leung-Chu, Jennifer, Liu, Jing, Beil, Michael, Fu, Fumin, Chen, Wei, Cumin, Frederic, Wiesmann, Christian, Mogi, Muneto

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Unique hydrogen bonding in the acetone‐mediated helical structure of (R,R)‐3,3′‐bisBINOL von Kawanami, Toshio, Ishizuka, Kentaro, Furuno, Hiroshi, Inanaga, Junji

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Remarkable effect of tris(4-fluorophenyl)phosphine oxide on the stabilization of chiral lanthanum complex catalysts. A new and practical protocol for the highly enantioselective ep... von Kino, Rie, Daikai, Kazuhiro, Kawanami, Toshio, Furuno, Hiroshi, Inanaga, Junji

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Palladium catalyzed cross-coupling reaction of 5-tributylstannyl-4-fluoropyrazole von Hanamoto, Takeshi, Koga, Yukinori, Kido, Eisaku, Kawanami, Toshio, Furuno, Hiroshi, Inanaga, Junji

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