G2 checkpoint abrogators as anticancer drugs von Kawabe, Takumi

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Involvement of the Interaction between p21 and Proliferating Cell Nuclear Antigen for the Maintenance of G2/M Arrest after DNA Damage von Ando, T, Kawabe, T, Ohara, H, Ducommun, B, Itoh, M, Okamoto, T

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CBP501-calmodulin binding contributes to sensitizing tumor cells to cisplatin and bleomycin von Mine, Naoki, Yamamoto, Sayaka, Saito, Naoya, Yamazaki, Satoshi, Suda, Chikako, Ishigaki, Machiyo, Kufe, Donald W, Von Hoff, Daniel D, Kawabe, Takumi

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Screening of a library of T7 phage-displayed peptides identifies alphaC helix in 14-3-3 protein as a CBP501-binding site von Matsumoto, Yuki, Shindo, Yosuke, Takakusagi, Yoichi, Takakusagi, Kaori, Tsukuda, Senko, Kusayanagi, Tomoe, Sato, Hitoshi, Kawabe, Takumi, Sugawara, Fumio, Sakaguchi, Kengo

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Cdc25C interacts with PCNA at G2/M transition von Kawabe, Takumi, Suganuma, Masashi, Ando, Tomoaki, Kimura, Mayumi, Hori, Haruna, Okamoto, Takashi

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Demonstration of carbon-nanotube tip preparation by Local melting method von Kawabe, Takumi, Takeuchi, Takahiro, Akiyama, Kouzirou, Shiraki, Ichiro

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Identi fi cation of U83836E as a gamma-glutamylcyclotransferase inhibitor that suppresses MCF7 breast cancer xenograft growth von Ii, Hiromi, Nohara, Yukie, Yoshiya, Taku, Masuda, Shun, Tsuda, Shugo, Oishi, Shinya, Friedman, Jonathan, Kawabe, Takumi, Nakata, Susumu

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NF-κB subunit p65 binds to 53BP2 and inhibits cell death induced by 53BP2 von YANG, J.-P, HORI, M, TAKAHASHI, N, KAWABE, T, KATO, H, OKAMOTO, T

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Identification of U83836E as a γ-glutamylcyclotransferase inhibitor that suppresses MCF7 breast cancer xenograft growth von Ii, Hiromi, Nohara, Yukie, Yoshiya, Taku, Masuda, Shun, Tsuda, Shugo, Oishi, Shinya, Friedman, Jonathan, Kawabe, Takumi, Nakata, Susumu

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G2 checkpoint abrogation as a cancer specific, cell cycle disruption von Kawabe, Takumi

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CBS9106 is a novel reversible oral CRM1 inhibitor with CRM1 degrading activity von Sakakibara, Keiichi, Saito, Naoya, Sato, Takuji, Suzuki, Atsushi, Hasegawa, Yoko, Friedman, Jonathan M., Kufe, Donald W., VonHoff, Daniel D., Iwami, Tadahiko, Kawabe, Takumi

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Abstract CT228: Phase Ib clinical study of CBP501, cisplatin and nivolumab administered every 3 weeks in patients with advanced refractory tumors. Dose escalation cohort von Matrana, Marc, Tsai, Frank, Satti, Suma, Cleary, James, Estes, Jacob, Do, Khanh, Kolmakov, Valentin, Kawabe, Takumi, Shapiro, Geoffrey I.

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Boromycin Abrogates Bleomycin-induced G2 Checkpoint von ARAI, MASAYOSHI, KOIZUMI, YUKIO, SATO, HITOSHI, KAWABE, TAKUMI, SUGANUMA, MASASHI, KOBAYASHI, HIDETAKA, TOMODA, HIROSHI, OMURA, SATOSHI

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CBP501 inhibits EGF-dependent cell migration, invasion and epithelial-to-mesenchymal transition of non-small cell lung cancer cells by blocking KRas to calmodulin binding von Saito, Naoya, Mine, Naoki, Kufe, Donald W, Von Hoff, Daniel D, Kawabe, Takumi

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Phase Ib clinical study of CBP501, cisplatin, and nivolumab administered every three weeks in patients with advanced refractory tumors: Efficacy in dose-escalation and expansion co... von Matrana, Marc Ryan, Tsai, Frank, Cleary, James M., Satti, Suma, Borazanci, Erkut, Estes, Jacob, Moser, Justin, Do, Khanh Tu, Du, Lingling, Sharma, Sunil, Khemka, Vivek, Kolmakov, Valentin, Kawabe, Takumi, Shapiro, Geoffrey

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CBP501 induces immunogenic tumor cell death and CD8 T cell infiltration into tumors in combination with platinum, and increases the efficacy of immune checkpoint inhibitors against... von Sakakibara, Keiichi, Sato, Takuji, Kufe, Donald W, VonHoff, Daniel D, Kawabe, Takumi

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CBS9106-induced CRM1 degradation is mediated by cullin ring ligase activity and the neddylation pathway von Saito, Naoya, Sakakibara, Keiichi, Sato, Takuji, Friedman, Jonathan M, Kufe, Donald W, VonHoff, Daniel D, Kawabe, Takumi

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Abstract A110: CBP501 suppresses cell migration, invasion and epithelial-mesenchymal transition (EMT) in non-small cell lung carcinoma von Saito, Naoya, Mine, Naoki, Kufe, Donald W., Von Hoff, Daniel D., Kawabe, Takumi

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Abstract C106: CBP501 potentiates the appearance of cisplatin-induced indicators of immunogenic cell death and promotes anti-tumor effects in an immuno-competent mouse model von Sakakibara, Keiichi, Sato, Takuji, Kufe, Donald W., Von Hoff, Daniel D., Kawabe, Takumi

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Activation of Nrf2 pathways correlates with resistance of NSCLC cell lines to CBP501 in vitro von Mine, Naoki, Yamamoto, Sayaka, Kufe, Donald W, Von Hoff, Daniel D, Kawabe, Takumi

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