Monitoring protease activity in biological tissues using antibody prodrugs as sensing probes von Vasiljeva, Olga, Menendez, Elizabeth, Nguyen, Margaret, Craik, Charles S., Michael Kavanaugh, W.

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The pathogenic biomarker alcohol dehydrogenase protein is involved in Bacillus cereus virulence and survival against host innate defence von Kavanaugh, Devon W, Porrini, Constance, Dervyn, Rozenn, Ramarao, Nalini

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Exposure of Bifidobacterium longum subsp. infantis to Milk Oligosaccharides Increases Adhesion to Epithelial Cells and Induces a Substantial Transcriptional Response von Kavanaugh, Devon W, O'Callaghan, John, Buttó, Ludovica F, Slattery, Helen, Lane, Jonathan, Clyne, Marguerite, Kane, Marian, Joshi, Lokesh, Hickey, Rita M

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Molecular basis for intestinal mucin recognition by galectin‐3 and C‐type lectins von Leclaire, Charlotte, Lecointe, Karine, Gunning, Patrick A., Tribolo, Sandra, Kavanaugh, Devon W., Wittmann, Alexandra, Latousakis, Dimitrios, MacKenzie, Donald A., Kawasaki, Norihito, Juge, Nathalie

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A phase I, first in human study of FP-1039 (GSK3052230), a novel FGF ligand trap, in patients with advanced solid tumors von Tolcher, A.W., Papadopoulos, K.P., Patnaik, A., Wilson, K., Thayer, S., Zanghi, J., Gemo, A.T., Kavanaugh, W.M., Keer, H.N., LoRusso, P.M.

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A Probody T Cell-Engaging Bispecific Antibody Targeting EGFR and CD3 Inhibits Colon Cancer Growth with Limited Toxicity von Boustany, Leila M, LaPorte, Sherry L, Wong, Laurie, White, Clayton, Vinod, Veena, Shen, Joel, Yu, Wendy, Koditek, David, Winter, Michael B, Moore, Stephen J, Mei, Li, Diep, Linnea, Huang, Yuanhui, Liu, Shouchun, Vasiljeva, Olga, West, Jim, Richardson, Jennifer, Irving, Bryan, Belvin, Marcia, Kavanaugh, W Michael

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Muscle-Specific Deletion of Toll-like Receptor 4 Impairs Metabolic Adaptation to Wheel Running in Mice von ALI, MOSTAFA M., MCMILLAN, RYAN P., FAUSNACHT, DANE W., KAVANAUGH, JOHN W., HARVEY, MORDECAI M., STEVENS, JOSEPH R., WU, YARU, MYNATT, RANDALL L., HULVER, MATTHEW W.

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Quantitative Systems Pharmacology Model of a Masked, Tumor‐Activated Antibody von Stroh, Mark, Sagert, Jason, Burke, John M., Apgar, Joshua F., Lin, Lin, Millard, Bjorn L., Michael Kavanaugh, W.

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Identification of a New Pathogenicity Island Within the Large pAH187_270 Plasmid Involved in Bacillus cereus Virulence von Dervyn, Rozenn, Kavanaugh, Devon W, Cormontagne, Delphine, Glasset, Benjamin, Ramarao, Nalini

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Nonclinical Efficacy and Safety of CX-2029, an Anti-CD71 Probody-Drug Conjugate von Singh, Shweta, Serwer, Laura, DuPage, Amy, Elkins, Kristi, Chauhan, Niharika, Ravn, Matthew, Buchanan, Fritz, Wang, Leyu, Krimm, Michael, Wong, Ken, Sagert, Jason, Tipton, Kimberly, Moore, Stephen J, Huang, Yuanhui, Jang, Andrew, Ureno, Eric, Miller, Adam, Patrick, Sarah, Duvur, Shanti, Liu, Shouchun, Vasiljeva, Olga, Li, Yingchun, Henriques, Tracy, Badagnani, Ilaria, Jeffries, Shawn, Schleyer, Siew, Leanna, Rob, Krebber, Claus, Viswanathan, Sridhar, Desnoyers, Luc, Terrett, Jonathan, Belvin, Marcia, Morgan-Lappe, Susan, Kavanaugh, W Michael, Richardson, Jennifer

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Deorphanization of the human leukocyte tyrosine kinase (LTK) receptor by a signaling screen of the extracellular proteome von Zhang, Hongbing, Pao, Lily I., Zhou, Aileen, Brace, Arthur D., Halenbeck, Robert, Hsu, Amy W., Bray, Thomas L., Hestir, Kevin, Bosch, Elizabeth, Lee, Ernestine, Wang, Gang, Liu, Haixia, Wong, Brian R., Kavanaugh, W. Michael, Williams, Lewis T.

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Model‐Informed Drug Development of the Masked Anti‑PD‑L1 Antibody CX‐072 von Stroh, Mark, Green, Michelle, Millard, Bjorn L., Apgar, Joshua F., Burke, John M., Garner, Will, Lu, Hong, Lyman, Susan K., Desnoyers, Luc R., Richardson, Jennifer, Hannah, Alison, Kavanaugh, W. Michael

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An Alternative to SH2 Domains for Binding Tyrosine-Phosphorylated Proteins von Kavanaugh, W. Michael, Williams, Lewis T.

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In vivo imaging of protease activity by Probody therapeutic activation von Wong, Kenneth R., Menendez, Elizabeth, Craik, Charles S., Kavanaugh, W. Michael, Vasiljeva, Olga

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A specific product of phosphatidylinositol 3-kinase directly activates the protein kinase Akt through its pleckstrin homology domain von Klippel, Anke, Kavanaugh, W. Michael, Pot, David, Williams, Lewis T.

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Conditional PD-1/PD-L1 Probody Therapeutics Induce Comparable Antitumor Immunity but Reduced Systemic Toxicity Compared with Traditional Anti-PD-1/PD-L1 Agents von Assi, Hikmat H, Wong, Chihunt, Tipton, Kimberly A, Mei, Li, Wong, Ken, Razo, Jennifer, Chan, Chanty, Howng, Bruce, Sagert, Jason, Krimm, Michael, Diep, Linnea, Jang, Andrew, Nguyen, Margaret T, Lapuyade, Nicole, Singson, Victoria, Villanueva, Ruth, Paidhungat, Madan, Liu, Shouchun, Rangan, Vangipuram, Vasiljeva, Olga, West, James W, Richardson, Jennifer H, Irving, Bryan, Daniel, Dylan, Belvin, Marcia, Kavanaugh, W Michael

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Membrane localization of phosphatidylinositol 3-kinase is sufficient to activate multiple signal-transducing kinase pathways von Klippel, Anke, Reinhard, Christoph, Kavanaugh, W. Michael, Apell, Gerald, Escobedo, Maria-Amelia, Williams, Lewis T.

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New genetic biomarkers to differentiate non-pathogenic from clinically relevant Bacillus cereus strains von Kavanaugh, Devon W., Glasset, Benjamin, Dervyn, Rozenn, Guérin, Cyprien, Plancade, Sandra, Herbin, Sabine, Brisabois, Anne, Nicolas, Pierre, Ramarao, Nalini

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A Pilot Screen of a Novel Peptide Hormone Library Identified Candidate GPR83 Ligands von Sallee, Nathan A., Lee, Ernestine, Leffert, Atossa, Ramirez, Silvia, Brace, Arthur D., Halenbeck, Robert, Kavanaugh, W. Michael, Sullivan, Kathleen M. C.

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Activation of Phosphatidylinositol 3-Kinase Is Sufficient for Cell Cycle Entry and Promotes Cellular Changes Characteristic of Oncogenic Transformation von Klippel, Anke, Escobedo, Maria-Amelia, Wachowicz, Matthew S., Apell, Gerald, Brown, Timothy W., Giedlin, Martin A., Kavanaugh, W. Michael, Williams, Lewis T.

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