Discovering the first microRNA-targeted drug von Lindow, Morten, Kauppinen, Sakari

Volltext

Development of microRNA therapeutics is coming of age von van Rooij, Eva, Kauppinen, Sakari

Volltext

Treatment of HCV Infection by Targeting MicroRNA von Janssen, Harry L.A, Reesink, Hendrik W, Lawitz, Eric J, Zeuzem, Stefan, Rodriguez-Torres, Maribel, Patel, Keyur, van der Meer, Adriaan J, Patick, Amy K, Chen, Alice, Zhou, Yi, Persson, Robert, King, Barney D, Kauppinen, Sakari, Levin, Arthur A, Hodges, Michael R

Volltext

Intragenic antagonistic roles of protein and circRNA in tumorigenesis von Guarnerio, Jlenia, Zhang, Yang, Cheloni, Giulia, Panella, Riccardo, Mae Katon, Jesse, Simpson, Mark, Matsumoto, Akinobu, Papa, Antonella, Loretelli, Cristian, Petri, Andreas, Kauppinen, Sakari, Garbutt, Cassandra, Nielsen, Gunnlaugur Petur, Deshpande, Vikram, Castillo-Martin, Mireia, Cordon-Cardo, Carlos, Dimitrios, Spentzos, Clohessy, John G., Batish, Mona, Pandolfi, Pier Paolo

Volltext

Clinical advances of RNA therapeutics for treatment of neurological and neuromuscular diseases von Holm, Anja, Hansen, Stine N., Klitgaard, Henrik, Kauppinen, Sakari

Volltext

Inhibition of microRNA function by antimiR oligonucleotides von Stenvang, Jan, Petri, Andreas, Lindow, Morten, Obad, Susanna, Kauppinen, Sakari

Volltext

microRNA-9 targets the long non-coding RNA MALAT1 for degradation in the nucleus von Leucci, Eleonora, Patella, Francesca, Waage, Johannes, Holmstrøm, Kim, Lindow, Morten, Porse, Bo, Kauppinen, Sakari, Lund, Anders H.

Volltext

MicroRNA-138 regulates osteogenic differentiation of human stromal (mesenchymal) stem cells in vivo von Eskildsen, Tilde, Taipaleenmäki, Hanna, Stenvang, Jan, Abdallah, Basem M, Ditzel, Nicholas, Nossent, Anne Yael, Bak, Mads, Kauppinen, Sakari, Kassem, Moustapha

Volltext

Silencing of microRNA families by seed-targeting tiny LNAs von Obad, Susanna, dos Santos, Camila O, Petri, Andreas, Heidenblad, Markus, Broom, Oliver, Ruse, Cristian, Fu, Cexiong, Lindow, Morten, Stenvang, Jan, Straarup, Ellen Marie, Hansen, Henrik Frydenlund, Koch, Troels, Pappin, Darryl, Hannon, Gregory J, Kauppinen, Sakari

Volltext

Loss of microRNA cluster miR-29a/b-1 in sporadic Alzheimer's disease correlates with increased BACE1/β-secretase expression von Hébert, Sébastien S, Horré, Katrien, Nicolaï, Laura, Papadopoulou, Aikaterini S, Mandemakers, Wim, Silahtaroglu, Asli N, Kauppinen, Sakari, Delacourte, André, De Strooper, Bart

Volltext

Therapeutic inhibition of the miR-34 family attenuates pathological cardiac remodeling and improves heart function von Bernardo, Bianca C, Gao, Xiao-Ming, Winbanks, Catherine E, Boey, Esther J. H, Tham, Yow Keat, Kiriazis, Helen, Gregorevic, Paul, Obad, Susanna, Kauppinen, Sakari, Du, Xiao-Jun, Lin, Ruby C. Y, McMullen, Julie R

Volltext

Silencing of the miR-17∼92 Cluster Family Inhibits Medulloblastoma Progression von MURPHY, Brian L, OBAD, Susanna, BIHANNIC, Laure, AYRAULT, Olivier, ZINDY, Frederique, KAUPPINEN, Sakari, ROUSSEL, Martine F

Volltext

LNA-mediated microRNA silencing in non-human primates von Elmén, Joacim, Lindow, Morten, Schütz, Sylvia, Lawrence, Matthew, Petri, Andreas, Obad, Susanna, Lindholm, Marie, Hedtjärn, Maj, Hansen, Henrik Frydenlund, Berger, Urs, Gullans, Steven, Kearney, Phil, Sarnow, Peter, Straarup, Ellen Marie, Kauppinen, Sakari

Volltext

The long non-coding RNA HOXB-AS3 regulates ribosomal RNA transcription in NPM1-mutated acute myeloid leukemia von Papaioannou, Dimitrios, Petri, Andreas, Dovey, Oliver M., Terreri, Sara, Wang, Eric, Collins, Frances A., Woodward, Lauren A., Walker, Allison E., Nicolet, Deedra, Pepe, Felice, Kumchala, Prasanthi, Bill, Marius, Walker, Christopher J., Karunasiri, Malith, Mrózek, Krzysztof, Gardner, Miranda L., Camilotto, Virginia, Zitzer, Nina, Cooper, Jonathan L., Cai, Xiongwei, Rong-Mullins, Xiaoqing, Kohlschmidt, Jessica, Archer, Kellie J., Freitas, Michael A., Zheng, Yi, Lee, Robert J., Aifantis, Iannis, Vassiliou, George, Singh, Guramrit, Kauppinen, Sakari, Bloomfield, Clara D., Dorrance, Adrienne M., Garzon, Ramiro

Volltext

MicroRNA expression in the adult mouse central nervous system von Bak, Mads, Silahtaroglu, Asli, Møller, Morten, Christensen, Mette, Rath, Martin F, Skryabin, Boris, Tommerup, Niels, Kauppinen, Sakari

Volltext

Antagonism of microRNA-122 in mice by systemically administered LNA-antimiR leads to up-regulation of a large set of predicted target mRNAs in the liver von Elmén, Joacim, Lindow, Morten, Silahtaroglu, Asli, Bak, Mads, Christensen, Mette, Lind-Thomsen, Allan, Hedtjärn, Maj, Hansen, Jens Bo, Hansen, Henrik Frydenlund, Straarup, Ellen Marie, McCullagh, Keith, Kearney, Phil, Kauppinen, Sakari

Volltext

An intranasal ASO therapeutic targeting SARS-CoV-2 von Zhu, Chi, Lee, Justin Y., Woo, Jia Z., Xu, Lei, Nguyenla, Xammy, Yamashiro, Livia H., Ji, Fei, Biering, Scott B., Van Dis, Erik, Gonzalez, Federico, Fox, Douglas, Wehri, Eddie, Rustagi, Arjun, Pinsky, Benjamin A., Schaletzky, Julia, Blish, Catherine A., Chiu, Charles, Harris, Eva, Sadreyev, Ruslan I., Stanley, Sarah, Kauppinen, Sakari, Rouskin, Silvi, Näär, Anders M.

Volltext

Altered MicroRNA Expression Confined to Specific Epithelial Cell Subpopulations in Breast Cancer von SEMPERE, Lorenzo F, CHRISTENSEN, Mette, SILAHTAROGLU, Asli, BAK, Mads, HEATH, Catherine V, SCHWARTZ, Gary, WELLS, Wendy, KAUPPINEN, Sakari, COLE, Charles N

Volltext

Long Non-Coding RNAs in Liver Cancer and Nonalcoholic Steatohepatitis von Uchida, Shizuka, Kauppinen, Sakari

Volltext

In situ detection of miRNAs in animal embryos using LNA-modified oligonucleotide probes von Kloosterman, Wigard P, Wienholds, Erno, de Bruijn, Ewart, Kauppinen, Sakari, Plasterk, Ronald H A

Volltext