Novel oral SPT inhibitor CH5169356 inhibits hepatic stellate cell activation and ameliorates hepatic fibrosis in mouse models of non‐alcoholic steatohepatitis (NASH) von Hada, Natsuko, Katsume, Asao, Kenichi, Kawasaki, Endo, Chihiro, Horiba, Naoshi, Sudoh, Masayuki

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Pathogenesis of Hepatitis C Virus Infection in Tupaia belangeri von AMAKO, Yutaka, TSUKIYAMA-KOHARA, Kyoko, KOHARA, Michinori, KATSUME, Asao, HIRATA, Yuichi, SEKIGUCHI, Satoshi, TOBITA, Yoshimi, HAYASHI, Yukiko, HISHIMA, Tsunekazu, FUNATA, Nobuaki, YONEKAWA, Hiromichi

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Self-enhancement of hepatitis C virus replication by promotion of specific sphingolipid biosynthesis von Hirata, Yuichi, Ikeda, Kazutaka, Sudoh, Masayuki, Tokunaga, Yuko, Suzuki, Akemi, Weng, Leiyun, Ohta, Masatoshi, Tobita, Yoshimi, Okano, Ken, Ozeki, Kazuhisa, Kawasaki, Kenichi, Tsukuda, Takuo, Katsume, Asao, Aoki, Yuko, Umehara, Takuya, Sekiguchi, Satoshi, Toyoda, Tetsuya, Shimotohno, Kunitada, Soga, Tomoyoshi, Nishijima, Masahiro, Taguchi, Ryo, Kohara, Michinori

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Host sphingolipid biosynthesis as a target for hepatitis C virus therapy von Sakamoto, Hiroshi, Okamoto, Koichi, Aoki, Masahiro, Kato, Hideyuki, Katsume, Asao, Ohta, Atsunori, Tsukuda, Takuo, Shimma, Nobuo, Aoki, Yuko, Arisawa, Mikio, Kohara, Michinori, Sudoh, Masayuki

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A Serine Palmitoyltransferase Inhibitor Blocks Hepatitis C Virus Replication in Human Hepatocytes von Katsume, Asao, Tokunaga, Yuko, Hirata, Yuichi, Munakata, Tsubasa, Saito, Makoto, Hayashi, Hitohisa, Okamoto, Koichi, Ohmori, Yusuke, Kusanagi, Isamu, Fujiwara, Shinya, Tsukuda, Takuo, Aoki, Yuko, Klumpp, Klaus, Tsukiyama–Kohara, Kyoko, El–Gohary, Ahmed, Sudoh, Masayuki, Kohara, Michinori

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Adipose tissue reduction in mice lacking the translational inhibitor 4E-BP1 von Tsukiyama-Kohara, Kyoko, Poulin, Francis, Kohara, Michinori, DeMaria, Christine T., Cheng, Alan, Wu, Zhidan, Gingras, Anne-Claude, Katsume, Asao, Elchebly, Mounib, Spiegelman, Bruce M., Harper, Mary-Ellen, Tremblay, Michel L., Sonenberg, Nahum

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An orally available, small-molecule interferon inhibits viral replication von Konishi, Hideyuki, Okamoto, Koichi, Ohmori, Yusuke, Yoshino, Hitoshi, Ohmori, Hiroshi, Ashihara, Motooki, Hirata, Yuichi, Ohta, Atsunori, Sakamoto, Hiroshi, Hada, Natsuko, Katsume, Asao, Kohara, Michinori, Morikawa, Kazumi, Tsukuda, Takuo, Shimma, Nobuo, Foster, Graham R., Alazawi, William, Aoki, Yuko, Arisawa, Mikio, Sudoh, Masayuki

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4E‐BP1 regulates the differentiation of white adipose tissue von Tsukiyama‐Kohara, Kyoko, Katsume, Asao, Kimura, Kazuhiro, Saito, Masayuki, Kohara, Michinori

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ANTI-INTERLEUKIN 6 (IL-6) RECEPTOR ANTIBODY SUPPRESSES CASTLEMAN'S DISEASE LIKE SYMPTOMS EMERGED IN IL-6 TRANSGENIC MICE von Katsume, Asao, Saito, Hiroyuki, Yamada, Yoshiki, Yorozu, Keigo, Ueda, Otoya, Akamatsu, Ken-Ichi, Nishimoto, Norihiro, Kishimoto, Tadamitsu, Yoshizaki, Kazuyuki, Ohsugi, Yoshiyuki

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An improved mouse model that rapidly develops fibrosis in non-alcoholic steatohepatitis von Matsumoto, Masahiko, Hada, Natsuko, Sakamaki, Yoshiyuki, Uno, Akiko, Shiga, Toshihiko, Tanaka, Chiaki, Ito, Tsuneo, Katsume, Asao, Sudoh, Masayuki

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Enantioselective synthesis of derivatives and structure–activity relationship study in the development of NA255 as a novel host-targeting anti-HCV agent von Kawasaki, Ken-ichi, Masubuchi, Miyako, Hayase, Tadakatsu, Komiyama, Susumu, Watanabe, Fumio, Fukuda, Hiroshi, Murata, Takeshi, Matsubara, Yasuaki, Koyama, Kouhei, Shindoh, Hidetoshi, Sakamoto, Hiroshi, Okamato, Kohichi, Ohta, Atsunori, Katsume, Asao, Aoki, Masahiro, Aoki, Yuko, Shimma, Nobuo, Sudoh, Masayuki, Tsukuda, Takuo

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Activation of the CKI-CDK-Rb-E2F Pathway in Full Genome Hepatitis C Virus-expressing Cells von Tsukiyama-Kohara, Kyoko, Toné, Shigenobu, Maruyama, Isao, Inoue, Kazuaki, Katsume, Asao, Nuriya, Hideko, Ohmori, Hiroshi, Ohkawa, Jun, Taira, Kazunari, Hoshikawa, Yutaka, Shibasaki, Futoshi, Reth, Michael, Minatogawa, Yohsuke, Kohara, Michinori

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Efficient Conditional Transgene Expression in Hepatitis C Virus cDNA Transgenic Mice Mediated by the Cre/loxP System von Wakita, Takaji, Taya, Choji, Katsume, Asao, Kato, Junko, Yonekawa, Hiromichi, Kanegae, Yumi, Saito, Izumu, Hayashi, Yukiko, Koike, Morio, Kohara, Michinori

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Pax6 Controls the Expression of Lewis x Epitope in the Embryonic Forebrain by Regulating α1,3-Fucosyltransferase IX Expression von Shimoda, Yasushi, Tajima, Youichi, Osanai, Taka, Katsume, Asao, Kohara, Michinori, Kudo, Takashi, Narimatsu, Hisashi, Takashima, Noriko, Ishii, Yasuo, Nakamura, Shun, Osumi, Noriko, Sanai, Yutaka

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4E‐ BP 1 regulates the differentiation of white adipose tissue von Tsukiyama‐Kohara, Kyoko, Katsume, Asao, Kimura, Kazuhiro, Saito, Masayuki, Kohara, Michinori

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Real-time detection system for quantification of hepatitis C virus genome von Takeuchi, Tomoko, Katsume, Asao, Tanaka, Takeshi, Abe, Aki, Inoue, Kazuaki, Tsukiyama-Kohara, Kyoko, Kawaguchi, Ryuji, Tanaka, Satoshi, Kohara, Michinori

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Interleukin 6 receptor antibody inhibits muscle atrophy and modulates proteolytic systems in interleukin 6 transgenic mice von Tsujinaka, T, Fujita, J, Ebisui, C, Yano, M, Kominami, E, Suzuki, K, Tanaka, K, Katsume, A, Ohsugi, Y, Shiozaki, H, Monden, M

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Cytomedical therapy for IgG1 plasmacytosis in human interleukin-6 transgenic mice using hybridoma cells microencapsulated in alginate-poly( l) lysine-alginate membrane von Okada, Naoki, Miyamoto, Hajime, Yoshioka, Tatsunobu, Katsume, Asao, Saito, Hiroyuki, Yorozu, Keigo, Ueda, Otoya, Itoh, Norio, Mizuguchi, Hiroyuki, Nakagawa, Shinsaku, Ohsugi, Yoshiyuki, Mayumi, Tadanori

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Prolongation of the Effective Duration of Cytomedical Therapy by Re-injecting SK2 Hybridoma Cells Microencapsulated within Alginate-Poly(L)lysine-Alginate Membranes into Human Inte... von MIYAMOTO, Hajime, OKADA, Naoki, YOSHIOKA, Tatsunobu, SUZUKI, Ryo, SAKAMOTO, Kayoko, KATSUME, Asao, SAITO, Hiroyuki, TSUTSUMI, Yasuo, KUBO, Kazuyoshi, NAKAGAWA, Shinsaku, OHSUGI, Yoshiyuki, MAYUMI, Tadanori

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Medical application of microencapsulating hybridoma cells in agarose microbeads `cytomedicine': therapeutic effect on IgG1 plasmacytosis and mesangio-proliferative glomerulonephrit... von Okada, Naoki, Miyamoto, Hajime, Kaneda, Yoshihisa, Yamamoto, Yoko, Katsume, Asao, Saito, Hiroyuki, Yorozu, Keigo, Ueda, Otoya, Tsutsumi, Yasuo, Nakagawa, Shinsaku, Ohsugi, Yoshiyuki, Mayumi, Tadanori

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