Current advances in humanized mouse models von Ito, Ryoji, Takahashi, Takeshi, Katano, Ikumi, Ito, Mamoru

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Antitumor Effect of Programmed Death-1 (PD-1) Blockade in Humanized the NOG-MHC Double Knockout Mouse von Ashizawa, Tadashi, Iizuka, Akira, Nonomura, Chizu, Kondou, Ryota, Maeda, Chie, Miyata, Haruo, Sugino, Takashi, Mitsuya, Koichi, Hayashi, Nakamasa, Nakasu, Yoko, Maruyama, Kouji, Yamaguchi, Ken, Katano, Ikumi, Ito, Mamoru, Akiyama, Yasuto

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Development of a novel humanized mouse model for improved evaluation of in vivo anti-cancer effects of anti-PD-1 antibody von Katano, Ikumi, Hanazawa, Asami, Otsuka, Iyo, Yamaguchi, Takuya, Mochizuki, Misa, Kawai, Kenji, Ito, Ryoji, Goto, Motohito, Kagawa, Takahiro, Takahashi, Takeshi

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Improved Detection of in vivo Human NK Cell-Mediated Antibody-Dependent Cellular Cytotoxicity Using a Novel NOG-FcγR-Deficient Human IL-15 Transgenic Mouse von Katano, Ikumi, Ito, Ryoji, Kawai, Kenji, Takahashi, Takeshi

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Generation of a Nonhuman Primate Model of Severe Combined Immunodeficiency Using Highly Efficient Genome Editing von Sato, Kenya, Oiwa, Ryo, Kumita, Wakako, Henry, Rachel, Sakuma, Tetsushi, Ito, Ryoji, Nozu, Ryoko, Inoue, Takashi, Katano, Ikumi, Sato, Kengo, Okahara, Norio, Okahara, Junko, Shimizu, Yoshihisa, Yamamoto, Masafumi, Hanazawa, Kisaburo, Kawakami, Takao, Kametani, Yoshie, Suzuki, Ryuji, Takahashi, Takeshi, Weinstein, Edward J., Yamamoto, Takashi, Sakakibara, Yasubumi, Habu, Sonoko, Hata, Jun-ichi, Okano, Hideyuki, Sasaki, Erika

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Report of the use of patient‐derived xenograft models in the development of anticancer drugs in Japan von Tsumura, Ryo, Koga, Yoshikatsu, Hamada, Akinobu, Kuwata, Takeshi, Sasaki, Hiroki, Doi, Toshihiko, Aikawa, Katsuji, Ohashi, Akihiro, Katano, Ikumi, Ikarashi, Yoshinori, Ito, Mamoru, Ochiai, Atsushi

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Establishment of a human allergy model using human IL-3/GM-CSF-transgenic NOG mice von Ito, Ryoji, Takahashi, Takeshi, Katano, Ikumi, Kawai, Kenji, Kamisako, Tsutomu, Ogura, Tomoyuki, Ida-Tanaka, Miyuki, Suemizu, Hiroshi, Nunomura, Satoshi, Ra, Chisei, Mori, Akio, Aiso, Sadakazu, Ito, Mamoru

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Long-term maintenance of peripheral blood derived human NK cells in a novel human IL-15- transgenic NOG mouse von Katano, Ikumi, Nishime, Chiyoko, Ito, Ryoji, Kamisako, Tsutomu, Mizusawa, Takuma, Ka, Yuyo, Ogura, Tomoyuki, Suemizu, Hiroshi, Kawakami, Yutaka, Ito, Mamoru, Takahashi, Takeshi

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Human Interleukin-34 facilitates microglia-like cell differentiation and persistent HIV-1 infection in humanized mice von Mathews, Saumi, Branch Woods, Amanda, Katano, Ikumi, Makarov, Edward, Thomas, Midhun B, Gendelman, Howard E, Poluektova, Larisa Y, Ito, Mamoru, Gorantla, Santhi

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Predominant development of mature and functional human NK cells in a novel human IL-2-producing transgenic NOG mouse von Katano, Ikumi, Takahashi, Takeshi, Ito, Ryoji, Kamisako, Tsutomu, Mizusawa, Takuma, Ka, Yuyo, Ogura, Tomoyuki, Suemizu, Hiroshi, Kawakami, Yutaka, Ito, Mamoru

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Generation of Human Immunosuppressive Myeloid Cell Populations in Human Interleukin-6 Transgenic NOG Mice von Hanazawa, Asami, Ito, Ryoji, Katano, Ikumi, Kawai, Kenji, Goto, Motohito, Suemizu, Hiroshi, Kawakami, Yutaka, Ito, Mamoru, Takahashi, Takeshi

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Bovine β-lactoglobulin-induced passive systemic anaphylaxis model using humanized NOG hIL-3/hGM-CSF transgenic mice von Ito, Ryoji, Katano, Ikumi, Otsuka, Iyo, Takahashi, Takeshi, Suemizu, Hiroshi, Ito, Mamoru, Simons, Peter J

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Generation of Novel Human Red Blood Cell-Bearing Humanized Mouse Models Based on C3-Deficient NOG Mice von Yamaguchi, Takuya, Katano, Ikumi, Otsuka, Iyo, Ito, Ryoji, Mochizuki, Misa, Goto, Motohito, Takahashi, Takeshi

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Recent Advances in Allergy Research Using Humanized Mice von Ito, Ryoji, Maruoka, Shuichiro, Gon, Yasuhiro, Katano, Ikumi, Takahashi, Takeshi, Ito, Mamoru, Izuhara, Kenji, Nunomura, Satoshi

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The analysis of the functions of human B and T cells in humanized NOD/shi-scid/γcnull (NOG) mice (hu-HSC NOG mice) von Watanabe, Yohei, Takahashi, Takeshi, Okajima, Akira, Shiokawa, Miho, Ishii, Naoto, Katano, Ikumi, Ito, Ryoji, Ito, Mamoru, Minegishi, Masayoshi, Minegishi, Naoko, Tsuchiya, Shigeru, Sugamura, Kazuo

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Induction of human humoral immune responses in a novel HLA-DR-expressing transgenic NOD/Shi-scid/γcnull mouse von Suzuki, Makiko, Takahashi, Takeshi, Katano, Ikumi, Ito, Ryoji, Ito, Mamoru, Harigae, Hideo, Ishii, Naoto, Sugamura, Kazuo

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Improved engraftment of human peripheral blood mononuclear cells in NOG MHC double knockout mice generated using CRISPR/Cas9 von Ka, Yuyo, Katano, Ikumi, Nishinaka, Eiko, Welcker, Jochen, Mochizuki, Misa, Kawai, Kenji, Goto, Motohito, Tomiyama, Kayo, Ogura, Tomoyuki, Yamamoto, Taichi, Ito, Mamoru, Ito, Ryoji, Takahashi, Riichi

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Enhanced Antibody Responses in a Novel NOG Transgenic Mouse with Restored Lymph Node Organogenesis von Takahashi, Takeshi, Katano, Ikumi, Ito, Ryoji, Goto, Motohito, Abe, Hayato, Mizuno, Seiya, Kawai, Kenji, Sugiyama, Fumihiro, Ito, Mamoru

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NOG-hIL-4-Tg, a new humanized mouse model for producing tumor antigen-specific IgG antibody by peptide vaccination von Kametani, Yoshie, Katano, Ikumi, Miyamoto, Asuka, Kikuchi, Yusuke, Ito, Ryoji, Muguruma, Yukari, Tsuda, Banri, Habu, Sonoko, Tokuda, Yutaka, Ando, Kiyoshi, Ito, Mamoru

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A humanized mouse model to study asthmatic airway inflammation via the human IL-33/IL-13 axis von Ito, Ryoji, Maruoka, Shuichiro, Soda, Kaori, Katano, Ikumi, Kawai, Kenji, Yagoto, Mika, Hanazawa, Asami, Takahashi, Takeshi, Ogura, Tomoyuki, Goto, Motohito, Takahashi, Riichi, Toyoshima, Shota, Okayama, Yoshimichi, Izuhara, Kenji, Gon, Yasuhiro, Hashimoto, Shu, Ito, Mamoru, Nunomura, Satoshi

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