High glucose couples DJ-1 with PTEN to activate PDGFRβ for renal proximal tubular cell injury von Das, Falguni, Ghosh-Choudhury, Nandini, Kasinath, Balakuntalam S., Sharma, Kumar, Choudhury, Goutam Ghosh

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TGFβ-stimulated microRNA-21 utilizes PTEN to orchestrate AKT/mTORC1 signaling for mesangial cell hypertrophy and matrix expansion von Dey, Nirmalya, Ghosh-Choudhury, Nandini, Kasinath, Balakuntalam S, Choudhury, Goutam Ghosh

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AMP-activated Protein Kinase (AMPK) Negatively Regulates Nox4-dependent Activation of p53 and Epithelial Cell Apoptosis in Diabetes von Eid, Assaad A., Ford, Bridget M., Block, Karen, Kasinath, Balakuntalam S., Gorin, Yves, Ghosh-Choudhury, Goutam, Barnes, Jeffrey L., Abboud, Hanna E.

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Knockout of Toll-Like Receptor-2 Attenuates Both the Proinflammatory State of Diabetes and Incipient Diabetic Nephropathy von Devaraj, Sridevi, Tobias, Peter, Kasinath, Balakuntalam S, Ramsamooj, Rajendra, Afify, Alaa, Jialal, Ishwarlal

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Disease drivers of aging von Hodes, Richard J., Sierra, Felipe, Austad, Steven N., Epel, Elissa, Neigh, Gretchen N., Erlandson, Kristine M., Schafer, Marissa J., LeBrasseur, Nathan K., Wiley, Christopher, Campisi, Judith, Sehl, Mary E., Scalia, Rosario, Eguchi, Satoru, Kasinath, Balakuntalam S., Halter, Jeffrey B., Cohen, Harvey Jay, Demark-Wahnefried, Wendy, Ahles, Tim A., Barzilai, Nir, Hurria, Arti, Hunt, Peter W.

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Deacetylation of S6 kinase promotes high glucose–induced glomerular mesangial cell hypertrophy and matrix protein accumulation von Das, Falguni, Maity, Soumya, Ghosh-Choudhury, Nandini, Kasinath, Balakuntalam S., Ghosh Choudhury, Goutam

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Tryptophan metabolites and anemia in patients with diabetic kidney disease von Debnath, Subrata, Thomas, Nimmy, Saliba, Afaf, Kottewar, Saket, Grant, Sheena, Kasinath, Balakuntalam S., Sharma, Kumar, Lorenzo, Carlos

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Akt2 causes TGFβ-induced deptor downregulation facilitating mTOR to drive podocyte hypertrophy and matrix protein expression von Das, Falguni, Ghosh-Choudhury, Nandini, Lee, Doug Yoon, Gorin, Yves, Kasinath, Balakuntalam S, Choudhury, Goutam Ghosh

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Fatigue characteristics on dialysis and non-dialysis days in patients with chronic kidney failure on maintenance hemodialysis von Debnath, Subrata, Rueda, Rain, Bansal, Shweta, Kasinath, Balakuntalam S, Sharma, Kumar, Lorenzo, Carlos

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MicroRNA-214 Reduces Insulin-like Growth Factor-1 (IGF-1) Receptor Expression and Downstream mTORC1 Signaling in Renal Carcinoma Cells von Das, Falguni, Dey, Nirmalya, Bera, Amit, Kasinath, Balakuntalam S., Ghosh-Choudhury, Nandini, Choudhury, Goutam Ghosh

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Hydrogen Sulfide Inhibits High Glucose-induced Matrix Protein Synthesis by Activating AMP-activated Protein Kinase in Renal Epithelial Cells von Lee, Hak Joo, Mariappan, Meenalakshmi M., Feliers, Denis, Cavaglieri, Rita C., Sataranatarajan, Kavithalakshmi, Abboud, Hanna E., Choudhury, Goutam Ghosh, Kasinath, Balakuntalam S.

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Symmetric dimethylarginine alters endothelial nitric oxide activity in glomerular endothelial cells von Feliers, Denis, Lee, Duck-Yoon, Gorin, Yves, Kasinath, Balakuntalam S.

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microRNA-21 governs TORC1 activation in renal cancer cell proliferation and invasion von Dey, Nirmalya, Das, Falguni, Ghosh-Choudhury, Nandini, Mandal, Chandi Charan, Parekh, Dipen J, Block, Karen, Kasinath, Balakuntalam S, Abboud, Hanna E, Choudhury, Goutam Ghosh

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A role for AMP-activated protein kinase in diabetes-induced renal hypertrophy von Lee, Myung-Ja, Feliers, Denis, Mariappan, Meenalakshmi M, Sataranatarajan, Kavithalakshmi, Mahimainathan, Lenin, Musi, Nicolas, Foretz, Marc, Viollet, Benoit, Weinberg, Joel M, Choudhury, Goutam Ghosh, Kasinath, Balakuntalam S

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TGFβ-induced deptor suppression recruits mTORC1 and not mTORC2 to enhance collagen I (α2) gene expression von Das, Falguni, Bera, Amit, Ghosh-Choudhury, Nandini, Abboud, Hanna E, Kasinath, Balakuntalam S, Choudhury, Goutam Ghosh

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The tumor suppressor TMEM127 regulates insulin sensitivity in a tissue-specific manner von Srikantan, Subramanya, Deng, Yilun, Cheng, Zi-Ming, Luo, Anqi, Qin, Yuejuan, Gao, Qing, Sande-Docor, Glaiza-Mae, Tao, Sifan, Zhang, Xingyu, Harper, Nathan, Shannon, Chris E., Fourcaudot, Marcel, Li, Zhi, Kasinath, Balakuntalam S., Harrison, Stephen, Ahuja, Sunil, Reddick, Robert L., Dong, Lily Q., Abdul-Ghani, Muhammad, Norton, Luke, Aguiar, Ricardo C. T., Dahia, Patricia L. M.

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Hydrogen Sulfide in Renal Physiology and Disease von Feliers, Denis, Lee, Hak Joo, Kasinath, Balakuntalam S

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TGFβ acts through PDGFRβ to activate mTORC1 via the Akt/PRAS40 axis and causes glomerular mesangial cell hypertrophy and matrix protein expression von Maity, Soumya, Das, Falguni, Kasinath, Balakuntalam S., Ghosh-Choudhury, Nandini, Ghosh Choudhury, Goutam

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High glucose upregulation of early-onset Parkinson's disease protein DJ-1 integrates the PRAS40/TORC1 axis to mesangial cell hypertrophy von Das, Falguni, Dey, Nirmalya, Venkatesan, Balachandar, Kasinath, Balakuntalam S., Ghosh-Choudhury, Nandini, Choudhury, Goutam Ghosh

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High glucose-induced downregulation of PTEN-Long is sufficient for proximal tubular cell injury in diabetic kidney disease von Das, Falguni, Ghosh-Choudhury, Nandini, Kasinath, Balakuntalam S., Sharma, Kumar, Choudhury, Goutam Ghosh

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