2-Acyl-tetrahydroisoquinoline-3-carboxylic Acids: Lead Compounds with Triple Actions, Peroxisome Proliferator-Activated Receptor α/γ Agonist and Protein-Tyrosine Phosphatase 1B Inh... von Otake, Kazuya, Azukizawa, Satoru, Takahashi, Kenji, Fukui, Masaki, Shibabayashi, Michiko, Kamemoto, Hikaru, Kasai, Masayasu, Shirahase, Hiroaki

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Novel prodrugs of meropenem with two lipophilic promoieties: synthesis and pharmacokinetics von Tanaka, Shunkichi, Matsui, Hiroshi, Kasai, Masayasu, Kunishiro, Kazuyoshi, Kakeya, Nobuharu, Shirahase, Hiroaki

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Novel Acyl-CoA: Cholesterol Acyltransferase Inhibitor: Indoline-Based Sulfamide Derivatives with Low Lipophilicity and Protein Binding Ratio von Takahashi, Kenji, Ohta, Masaru, Shoji, Yoshimichi, Kasai, Masayasu, Kunishiro, Kazuyoshi, Miike, Tomohiro, Kanda, Mamoru, Shirahase, Hiroaki

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A Novel Series of (S)-2,7-Substituted-1,2,3,4-tetrahydroisoquinoline-3-carboxylic Acids: Peroxisome Proliferator-Activated Receptor α/γ Dual Agonists with Protein-Tyrosine Phosphat... von Otake, Kazuya, Azukizawa, Satoru, Fukui, Masaki, Shibabayashi, Michiko, Kamemoto, Hikaru, Miike, Tomohiro, Kunishiro, Kazuyoshi, Kasai, Masayasu, Shirahase, Hiroaki

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Novel Tetrahydroisoquinoline Derivatives with Inhibitory Activities against Acyl-CoA: Cholesterol Acyltransferase and Lipid Peroxidation von Ohta, Masaru, Takahashi, Kenji, Kasai, Masayasu, Shoji, Yoshimichi, Kunishiro, Kazuyoshi, Miike, Tomohiro, Kanda, Mamoru, Mukai, Chisato, Shirahase, Hiroaki

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Synthesis and Biological Evaluation of (S)-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic Acids: A Novel Series of PPARγ Agonists von Azukizawa, Satoru, Kasai, Masayasu, Takahashi, Kenji, Miike, Tomohiro, Kunishiro, Kazuyoshi, Kanda, Mamoru, Mukai, Chisato, Shirahase, Hiroaki

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Synthesis and Biological Evaluation of (S)-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic Acids: A Novel Series of PPAR.GAMMA. Agonists von Azukizawa, Satoru, Kasai, Masayasu, Takahashi, Kenji, Miike, Tomohiro, Kunishiro, Kazuyoshi, Kanda, Mamoru, Mukai, Chisato, Shirahase, Hiroaki

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Novel (S)-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acids: Peroxisome proliferator-activated receptor γ selective agonists with protein-tyrosine phosphatase 1B inhibition von Otake, Kazuya, Azukizawa, Satoru, Fukui, Masaki, Kunishiro, Kazuyoshi, Kamemoto, Hikaru, Kanda, Mamoru, Miike, Tomohiro, Kasai, Masayasu, Shirahase, Hiroaki

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Novel Indoline-Based Acyl-CoA:Cholesterol Acyltransferase Inhibitor with Antiperoxidative Activity: Improvement of Physicochemical Properties and Biological Activities by Introduct... von Takahashi, Kenji, Kasai, Masayasu, Ohta, Masaru, Shoji, Yoshimichi, Kunishiro, Kazuyoshi, Kanda, Mamoru, Kurahashi, Kazuyoshi, Shirahase, Hiroaki

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Novel Acyl-CoA: Cholesterol Acyltransferase Inhibitor: Indoline-Based Sulfamide Derivatives with Low Lipophilicity and Protein Binding Ratio von Kenji TAKAHASHI, Masaru OHTA, Yoshimichi SHOJI, Masayasu KASAI, Kazuyoshi KUNISHIRO, Tomohiro MIIKE, Mamoru KANDA, Hiroaki SHIRAHASE

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Novel Tetrahydroisoquinoline Derivatives with Inhibitory Activities against Acyl-CoA: Cholesterol Acyltransferase and Lipid Peroxidation von Masaru OHTAa, b, Kenji TAKAHASHIa, Masayasu KASAIa, Yoshimichi SHOJIa, Kazuyoshi KUNISHIROa, Tomohiro MIIKEa, Mamoru KANDAa, Chisato MUKAIb, Hiroaki SHIRAHASEa

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A Novel Series of Thromboxane A2 Synthetase Inhibitors with Free Radical Scavenging and Anti-peroxidative Activities von KAMIYA, Shoji, SHIRAHASE, Hiroaki, NAKAMURA, Shohei, KANDA, Mamoru, MATSUI, Hiroshi, YOSHIMI, Akihisa, KASAI, Masayasu, TAKAHASHI, Kenji, KURAHASHI, Kazuyoshi

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Bioavailable Acyl-CoA : Cholesterol Acyltransferase Inhibitor with Anti-peroxidative Activity : Synthesis and Biological Activity of Novel Indolinyl Amide and Urea Derivatives von KAMIYA, Shoji, SHIRAHASE, Hiroaki, YOSHIMI, Akihisa, NAKAMURA, Shohei, KANDA, Mamoru, MATSUI, Hiroshi, KASAI, Masayasu, TAKAHASHI, Kenji, KURAHASHI, Kazuyoshi

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Novel (S)-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acids: Peroxisome proliferator-activated receptor γ selective agonists with protein-tyrosine phosphatase 1B inhibition: Sympos... von OTAKE, Kazuya, AZUKIZAWA, Satoru, FUKUI, Masaki, KUNISHIRO, Kazuyoshi, KAMEMOTO, Hikaru, KANDA, Mamoru, MIIKE, Tomohiro, KASAI, Masayasu, SHIRAHASE, Hiroaki

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2-Acyl-tetrahydroisoquinoline-3-carboxylic Acids von Otake, Kazuya, Azukizawa, Satoru, Takahashi, Kenji, Fukui, Masaki, Shibabayashi, Michiko, Kamemoto, Hikaru, Kasai, Masayasu, Shirahase, Hiroaki

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Novel indoline-based acyl-CoA: cholesterol acyltransferase inhibitor: Effects of introducing a methanesulfonamide group on physicochemical properties and biological activities von Shoji, Yoshimichi, Takahashi, Kenji, Ohta, Masaru, Kasai, Masayasu, Kunishiro, Kazuyoshi, Kanda, Mamoru, Yogai, Satoko, Takeuchi, Yasuo, Shirahase, Hiroaki

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AS-924, a Novel Orally Active Bifunctional Prodrug of Ceftizoxime. Synthesis and Relationship between Physicochemical Properties and Oral Absorption von KASAI, Masayasu, HATANO, Satoru, KITAGAWA, Meiko, YOSHIMI, Akihisa, NISHIMURA, Ken-ichi, MORI, Nobuhiro, SAKAI, Atsushi, SUGIHARA, Taisuke

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A Novel Series of (S)-2,7-Substituted-1,2,3,4-tetrahydroisoquinoline-3-carboxylic Acids von Otake, Kazuya, Azukizawa, Satoru, Fukui, Masaki, Shibabayashi, Michiko, Kamemoto, Hikaru, Miike, Tomohiro, Kunishiro, Kazuyoshi, Kasai, Masayasu, Shirahase, Hiroaki

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Novel Acyl-CoA: Cholesterol Acyltransferase Inhibitor von Takahashi, Kenji, Ohta, Masaru, Shoji, Yoshimichi, Kasai, Masayasu, Kunishiro, Kazuyoshi, Miike, Tomohiro, Kanda, Mamoru, Shirahase, Hiroaki

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Novel Tetrahydroisoquinoline Derivatives with Inhibitory Activities against Acyl-CoA von Ohta, Masaru, Takahashi, Kenji, Kasai, Masayasu, Shoji, Yoshimichi, Kunishiro, Kazuyoshi, Miike, Tomohiro, Kanda, Mamoru, Mukai, Chisato, Shirahase, Hiroaki

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